Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YFL005W
Length:
215
Number of sequences:
5887
Description:
YFL005W SEC4 SGDID:S000001889, Chr VI from 130334-130981, Genome Release 64-1-1, Verified ORF, "Rab family GTPase essential for vesicle-mediated exocytic secretion and autophagy; associates with the exocyst component Sec15p and may regulate polarized delivery of transport vesicles to the exocyst at the plasma membrane"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
451P62836    184   RAP1A_RAT Ras-related protein Rap-1A OS=Rattu...1654e-25     102     37     60GO:0005829; C:cytosol; TAS:Reactome.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
452P62835    184   RAP1A_MOUSE Ras-related protein Rap-1A OS=Mus...1654e-25     102     37     60GO:0032045; C:guanyl-nucleotide exchange factor complex; IDA:MGI.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IDA:MGI.::GO:0017016; F:Ras GTPase binding; IPI:MGI.
GO:0007264; P:small GTPase mediated signal transduction; IDA:MGI.
453P62834    184   RAP1A_HUMAN Ras-related protein Rap-1A OS=Hom...1654e-25     102     37     60GO:0005829; C:cytosol; TAS:Reactome.::GO:0005886; C:plasma membrane; TAS:Reactome.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; TAS:ProtInc.
GO:0000186; P:activation of MAPKK activity; TAS:Reactome.::GO:0006112; P:energy reserve metabolic process; TAS:Reactome.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0030168; P:platelet activation; TAS:Reactome.::GO:0050796; P:regulation of insulin secretion; TAS:Reactome.
454P62833    184   RAP1A_BOVIN Ras-related protein Rap-1A OS=Bos...1654e-25     102     37     60GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
455Q06AU5    226   RAB32_PIG Ras-related protein Rab-32 OS=Sus s...2094e-25     103     30     55GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0015031; P:protein transport; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
456P22123    184   RAPA_DISOM Ras-related protein O-Krev OS=Disc...1705e-25     101     36     58GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
457Q6IMM1    273   DJC27_CHICK DnaJ homolog subfamily C member 2...1886e-25     103     30     53
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0031072; F:heat shock protein binding; IEA:InterPro.::GO:0051082; F:unfolded protein binding; IEA:InterPro.
GO:0006457; P:protein folding; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
458Q5UQ27    215   RABL_MIMIV Probable Rab-related GTPase OS=Aca...1559e-25     101     36     60GO:0020002; C:host cell plasma membrane; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-KW.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
459P18613    186   RAPA_DICDI Ras-related protein rapA OS=Dictyo...1661e-24     100     35     58GO:0045335; C:phagocytic vesicle; IDA:dictyBase.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IDA:dictyBase.::GO:0003924; F:GTPase activity; IDA:dictyBase.::GO:0017160; F:Ral GTPase binding; IDA:dictyBase.
GO:0031289; P:actin phosphorylation; IMP:dictyBase.::GO:0006935; P:chemotaxis; IMP:dictyBase.::GO:0006972; P:hyperosmotic response; IMP:dictyBase.::GO:0030838; P:positive regulation of actin filament polymerization; IEP:dictyBase.::GO:0031284; P:positive regulation of guanylate cyclase activity; IMP:dictyBase.::GO:0043520; P:regulation of myosin II filament assembly; IMP:dictyBase.::GO:0046578; P:regulation of Ras protein signal transduction; IDA:dictyBase.::GO:0009409; P:response to cold; IEP:dictyBase.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
460P11233    206   RALA_HUMAN Ras-related protein Ral-A OS=Homo ...1791e-24     101     31     60GO:0009986; C:cell surface; IDA:UniProtKB.::GO:0032154; C:cleavage furrow; IDA:UniProtKB.::GO:0030496; C:midbody; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IDA:UniProtKB.
GO:0031755; F:Edg-2 lysophosphatidic acid receptor binding; IDA:UniProtKB.::GO:0005525; F:GTP binding; TAS:ProtInc.::GO:0003924; F:GTPase activity; IEA:InterPro.
GO:0031532; P:actin cytoskeleton reorganization; IDA:BHF-UCL.::GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0006935; P:chemotaxis; TAS:ProtInc.::GO:0000910; P:cytokinesis; IDA:UniProtKB.::GO:0006887; P:exocytosis; IEA:UniProtKB-KW.::GO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW.::GO:0051665; P:membrane raft localization; IDA:UniProtKB.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0051491; P:positive regulation of filopodium assembly; IDA:BHF-UCL.::GO:0007265; P:Ras protein signal transduction; TAS:Reactome.::GO:0017157; P:regulation of exocytosis; IDA:UniProtKB.
461P18262    178   RAS_ARTSA Ras-like protein OS=Artemia salina ...1542e-24     100     34     59GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
462P63320    206   RALA_SAGOE Ras-related protein Ral-A OS=Sagui...1792e-24     100     31     59GO:0009986; C:cell surface; IEA:UniProtKB-SubCell.::GO:0032154; C:cleavage furrow; ISS:UniProtKB.::GO:0030496; C:midbody; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; ISS:UniProtKB.
GO:0031755; F:Edg-2 lysophosphatidic acid receptor binding; ISS:UniProtKB.::GO:0005525; F:GTP binding; IDA:UniProtKB.::GO:0003924; F:GTPase activity; IEA:InterPro.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0000910; P:cytokinesis; ISS:UniProtKB.::GO:0006887; P:exocytosis; IEA:UniProtKB-KW.::GO:0051665; P:membrane raft localization; ISS:UniProtKB.::GO:0017157; P:regulation of exocytosis; ISS:UniProtKB.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
463P63322    206   RALA_RAT Ras-related protein Ral-A OS=Rattus ...1792e-24     100     31     59GO:0009986; C:cell surface; IEA:UniProtKB-SubCell.::GO:0032154; C:cleavage furrow; ISS:UniProtKB.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0030496; C:midbody; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; ISS:UniProtKB.
GO:0031755; F:Edg-2 lysophosphatidic acid receptor binding; ISS:UniProtKB.::GO:0005525; F:GTP binding; NAS:RGD.::GO:0003924; F:GTPase activity; IEA:InterPro.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0000910; P:cytokinesis; ISS:UniProtKB.::GO:0006887; P:exocytosis; IEA:UniProtKB-KW.::GO:0051665; P:membrane raft localization; ISS:UniProtKB.::GO:0017157; P:regulation of exocytosis; ISS:UniProtKB.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
464P63321    206   RALA_MOUSE Ras-related protein Ral-A OS=Mus m...1792e-24     100     31     59GO:0009986; C:cell surface; IEA:UniProtKB-SubCell.::GO:0032154; C:cleavage furrow; ISS:UniProtKB.::GO:0030496; C:midbody; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; ISS:UniProtKB.
GO:0031755; F:Edg-2 lysophosphatidic acid receptor binding; ISS:UniProtKB.::GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0000910; P:cytokinesis; ISS:UniProtKB.::GO:0006887; P:exocytosis; IEA:UniProtKB-KW.::GO:0051665; P:membrane raft localization; IDA:UniProtKB.::GO:0017157; P:regulation of exocytosis; IDA:UniProtKB.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
465Q99KL7    221   RAB28_MOUSE Ras-related protein Rab-28 OS=Mus...2173e-24     100     33     52GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0019003; F:GDP binding; ISS:UniProtKB.::GO:0005525; F:GTP binding; ISS:UniProtKB.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
466O82480    209   RAC7_ARATH Rac-like GTP-binding protein ARAC7...1795e-24     99.8     32     54GO:0005622; C:intracellular; IEA:InterPro.::GO:0005886; C:plasma membrane; IDA:TAIR.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0009738; P:abscisic acid mediated signaling pathway; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
467P51158    221   RAB28_RAT Ras-related protein Rab-28 OS=Rattu...2176e-24     99.8     32     52GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0019003; F:GDP binding; ISS:UniProtKB.::GO:0005525; F:GTP binding; ISS:UniProtKB.::GO:0003924; F:GTPase activity; TAS:RGD.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
468Q13637    225   RAB32_HUMAN Ras-related protein Rab-32 OS=Hom...1777e-24     99.8     32     57GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0015031; P:protein transport; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
469Q9UBK7    228   RBL2A_HUMAN Rab-like protein 2A OS=Homo sapie...1758e-24     99.8     33     54
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; TAS:ProtInc.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
470Q9UNT1    228   RBL2B_HUMAN Rab-like protein 2B OS=Homo sapie...1569e-24     99.4     33     54
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; TAS:ProtInc.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
471Q9CZE3    223   RAB32_MOUSE Ras-related protein Rab-32 OS=Mus...1711e-23     98.6     30     58GO:0005739; C:mitochondrion; IDA:MGI.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0015031; P:protein transport; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
472Q5F352    189   RASN_CHICK GTPase NRas OS=Gallus gallus (Chic...1612e-23     97.8     34     57GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
473P84096    191   RHOG_MOUSE Rho-related GTP-binding protein Rh...1682e-23     97.4     30     52GO:0005622; C:intracellular; IEA:InterPro.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:MGI.
GO:0032863; P:activation of Rac GTPase activity; ISS:UniProtKB.::GO:0060326; P:cell chemotaxis; ISS:UniProtKB.::GO:0090004; P:positive regulation of establishment of protein localization in plasma membrane; ISS:UniProtKB.
474P84095    191   RHOG_HUMAN Rho-related GTP-binding protein Rh...1682e-23     97.4     30     52GO:0005829; C:cytosol; TAS:Reactome.::GO:0005886; C:plasma membrane; TAS:Reactome.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IDA:MGI.::GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0030036; P:actin cytoskeleton organization; IDA:MGI.::GO:0032863; P:activation of Rac GTPase activity; IMP:UniProtKB.::GO:0007411; P:axon guidance; TAS:Reactome.::GO:0060326; P:cell chemotaxis; IMP:UniProtKB.::GO:0030168; P:platelet activation; TAS:Reactome.::GO:0008284; P:positive regulation of cell proliferation; TAS:ProtInc.::GO:0090004; P:positive regulation of establishment of protein localization in plasma membrane; IMP:UniProtKB.::GO:0045893; P:positive regulation of transcription, DNA-dependent; IDA:MGI.::GO:0016601; P:Rac protein signal transduction; IDA:MGI.::GO:0007266; P:Rho protein signal transduction; IDA:MGI.
475P84097    191   RHOG_CRICR Rho-related GTP-binding protein Rh...1682e-23     97.4     30     52GO:0005622; C:intracellular; IEA:InterPro.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0032863; P:activation of Rac GTPase activity; ISS:UniProtKB.::GO:0060326; P:cell chemotaxis; ISS:UniProtKB.::GO:0090004; P:positive regulation of establishment of protein localization in plasma membrane; ISS:UniProtKB.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
476Q5RDE5    273   DJC27_PONAB DnaJ homolog subfamily C member 2...1622e-23     99     31     56
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0031072; F:heat shock protein binding; IEA:InterPro.::GO:0051082; F:unfolded protein binding; IEA:InterPro.
GO:0006457; P:protein folding; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
477Q5RD87    189   RASN_PONAB GTPase NRas OS=Pongo abelii (Sumat...1513e-23     97.4     34     57GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
478Q95ME4    189   RASN_MONDO GTPase NRas OS=Monodelphis domesti...1743e-23     97.4     32     54GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
479Q01387    229   RAS2_NEUCR Protein ras-2 OS=1257 / FGSC 987)....1853e-23     98.2     30     53GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
480Q9NZQ0    273   DJC27_HUMAN DnaJ homolog subfamily C member 2...1623e-23     98.6     31     56
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0031072; F:heat shock protein binding; IEA:InterPro.::GO:0051082; F:unfolded protein binding; IEA:InterPro.
GO:0006457; P:protein folding; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
481P12825    189   RASN_CAVPO GTPase NRas OS=Cavia porcellus (Gu...1604e-23     97.1     34     56GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
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