Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YFL005W
Length:
215
Number of sequences:
5887
Description:
YFL005W SEC4 SGDID:S000001889, Chr VI from 130334-130981, Genome Release 64-1-1, Verified ORF, "Rab family GTPase essential for vesicle-mediated exocytic secretion and autophagy; associates with the exocyst component Sec15p and may regulate polarized delivery of transport vesicles to the exocyst at the plasma membrane"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
391P93267    207   RAB7_MESCR Ras-related protein Rab7A OS=cryst...1678e-32     120     40     61GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
392Q9C820    206   RAG3D_ARATH Ras-related protein RABG3d OS=Ara...1671e-31     120     39     62GO:0005794; C:Golgi apparatus; IDA:TAIR.::GO:0005886; C:plasma membrane; IDA:TAIR.::GO:0005774; C:vacuolar membrane; IDA:TAIR.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
393Q3T0F5    207   RAB7A_BOVIN Ras-related protein Rab-7a OS=Bos...1641e-31     120     37     60GO:0005770; C:late endosome; ISS:UniProtKB.::GO:0005764; C:lysosome; IEA:UniProtKB-SubCell.::GO:0042470; C:melanosome; IEA:UniProtKB-SubCell.::GO:0045335; C:phagocytic vesicle; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0045022; P:early endosome to late endosome transport; ISS:UniProtKB.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
394P35288    237   RAB23_MOUSE Ras-related protein Rab-23 OS=Mus...2002e-31     120     37     55GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
395Q9HDY0    208   YPT71_SCHPO GTP-binding protein ypt71 OS=Schi...2033e-31     119     35     60GO:0005829; C:cytosol; IDA:PomBase.::GO:0005744; C:mitochondrial inner membrane presequence translocase complex; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.::GO:0005773; C:vacuole; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IC:PomBase.::GO:0003924; F:GTPase activity; ISS:PomBase.
GO:0006897; P:endocytosis; ISS:PomBase.::GO:0006896; P:Golgi to vacuole transport; ISS:PomBase.::GO:0006886; P:intracellular protein transport; IC:PomBase.::GO:0061192; P:negative regulation of vacuole fusion, non-autophagic; IMP:PomBase.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
396Q9LW76    206   RAG3C_ARATH Ras-related protein RABG3c OS=Ara...1673e-31     118     39     63GO:0005794; C:Golgi apparatus; IDA:TAIR.::GO:0005634; C:nucleus; IDA:TAIR.::GO:0005886; C:plasma membrane; IDA:TAIR.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
397O24461    207   RAB7_PRUAR Ras-related protein Rab7 OS=Prunus...1675e-31     118     38     61GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
398Q54G48    218   RABO_DICDI Ras-related protein RabO OS=Dictyo...1712e-30     117     37     60GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
399Q8VEA8    199   RAB7B_MOUSE Ras-related protein Rab-7b OS=Mus...2002e-30     116     35     54GO:0005794; C:Golgi apparatus; ISS:UniProtKB.::GO:0005770; C:late endosome; IDA:UniProtKB.::GO:0005764; C:lysosome; IDA:UniProtKB.::GO:0005802; C:trans-Golgi network; ISS:UniProtKB.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0034499; P:late endosome to Golgi transport; ISS:UniProtKB.::GO:0034144; P:negative regulation of toll-like receptor 4 signaling pathway; IMP:UniProtKB.::GO:0034164; P:negative regulation of toll-like receptor 9 signaling pathway; IMP:UniProtKB.::GO:0032755; P:positive regulation of interleukin-6 production; ISS:UniProtKB.::GO:0045654; P:positive regulation of megakaryocyte differentiation; ISS:UniProtKB.::GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; ISS:UniProtKB.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
400Q9XI98    206   RAG3E_ARATH Ras-related protein RABG3e OS=Ara...1662e-30     116     37     60GO:0005794; C:Golgi apparatus; IDA:TAIR.::GO:0005886; C:plasma membrane; IDA:TAIR.::GO:0005774; C:vacuolar membrane; IDA:TAIR.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0006979; P:response to oxidative stress; IEP:TAIR.::GO:0009651; P:response to salt stress; IMP:TAIR.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
401Q9XER8    207   RAB7_GOSHI Ras-related protein Rab7 OS=Gossyp...1675e-30     115     37     62GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
402Q96AH8    199   RAB7B_HUMAN Ras-related protein Rab-7b OS=Hom...1988e-30     115     34     54GO:0005794; C:Golgi apparatus; IDA:UniProtKB.::GO:0005770; C:late endosome; IDA:UniProtKB.::GO:0005764; C:lysosome; IDA:UniProtKB.::GO:0005802; C:trans-Golgi network; IDA:UniProtKB.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0034499; P:late endosome to Golgi transport; IMP:UniProtKB.::GO:0034144; P:negative regulation of toll-like receptor 4 signaling pathway; ISS:UniProtKB.::GO:0034164; P:negative regulation of toll-like receptor 9 signaling pathway; ISS:UniProtKB.::GO:0032755; P:positive regulation of interleukin-6 production; IMP:UniProtKB.::GO:0045654; P:positive regulation of megakaryocyte differentiation; IMP:UniProtKB.::GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; IMP:UniProtKB.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
403Q5R4B8    206   RALB_PONAB Ras-related protein Ral-B OS=Pongo...1864e-29     113     33     62GO:0030496; C:midbody; ISS:UniProtKB.::GO:0005886; C:plasma membrane; ISS:UniProtKB.
GO:0005525; F:GTP binding; ISS:UniProtKB.::GO:0003924; F:GTPase activity; ISS:UniProtKB.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0000910; P:cytokinesis; ISS:UniProtKB.::GO:0001928; P:regulation of exocyst assembly; ISS:UniProtKB.::GO:0060178; P:regulation of exocyst localization; ISS:UniProtKB.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
404P11234    206   RALB_HUMAN Ras-related protein Ral-B OS=Homo ...1864e-29     113     33     62GO:0030496; C:midbody; IDA:UniProtKB.::GO:0005886; C:plasma membrane; IDA:UniProtKB.
GO:0005525; F:GTP binding; IDA:UniProtKB.::GO:0003924; F:GTPase activity; IDA:UniProtKB.::GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0000910; P:cytokinesis; IDA:UniProtKB.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0007265; P:Ras protein signal transduction; TAS:Reactome.::GO:0001928; P:regulation of exocyst assembly; ISS:UniProtKB.::GO:0060178; P:regulation of exocyst localization; ISS:UniProtKB.
405Q9H0N0    254   RAB6C_HUMAN Ras-related protein Rab-6C OS=Hom...1585e-29     114     36     59GO:0005813; C:centrosome; IDA:UniProtKB.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IDA:UniProtKB.
GO:0022402; P:cell cycle process; IMP:UniProtKB.::GO:0015031; P:protein transport; IEA:InterPro.::GO:0010824; P:regulation of centrosome duplication; IMP:UniProtKB.::GO:0042493; P:response to drug; IDA:UniProtKB.::GO:0007264; P:small GTPase mediated signal transduction; TAS:UniProtKB.
406Q4R379    206   RALB_MACFA Ras-related protein Ral-B OS=Macac...1865e-29     112     33     62GO:0030496; C:midbody; ISS:UniProtKB.::GO:0005886; C:plasma membrane; ISS:UniProtKB.
GO:0005525; F:GTP binding; ISS:UniProtKB.::GO:0003924; F:GTPase activity; ISS:UniProtKB.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0000910; P:cytokinesis; ISS:UniProtKB.::GO:0001928; P:regulation of exocyst assembly; ISS:UniProtKB.::GO:0060178; P:regulation of exocyst localization; ISS:UniProtKB.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
407P22124    206   RAL_DISOM Ras-related protein O-RAL OS=Discop...2127e-29     112     30     58GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
408Q8CAM5    267   RAB36_MOUSE Ras-related protein Rab-36 OS=Mus...2291e-28     113     31     49GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
409P41925    209   RYL2_YARLI Ras-like GTP-binding protein RYL2 ...2041e-28     112     34     53GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
410Q9JIW9    206   RALB_MOUSE Ras-related protein Ral-B OS=Mus m...2111e-28     112     33     57GO:0030496; C:midbody; ISS:UniProtKB.::GO:0005886; C:plasma membrane; ISS:UniProtKB.
GO:0005525; F:GTP binding; ISS:UniProtKB.::GO:0003924; F:GTPase activity; ISS:UniProtKB.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0000910; P:cytokinesis; ISS:UniProtKB.::GO:0001928; P:regulation of exocyst assembly; ISS:UniProtKB.::GO:0060178; P:regulation of exocyst localization; ISS:UniProtKB.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
411Q54K69    197   RAB7B_DICDI Ras-related protein Rab-7B OS=Dic...2032e-28     111     35     58
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
412P36018    234   YPT52_YEAST GTP-binding protein YPT52 OS=Sacc...2312e-28     112     31     52GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.::GO:0005770; C:late endosome; IMP:SGD.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IDA:SGD.::GO:0005515; F:protein binding; IPI:IntAct.
GO:0006897; P:endocytosis; IMP:SGD.::GO:0006623; P:protein targeting to vacuole; IMP:SGD.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
413Q948K6    204   RABG1_ARATH Ras-related protein RABG1 OS=Arab...1662e-28     111     39     58GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
414P36860    206   RALB_RAT Ras-related protein Ral-B OS=Rattus ...1856e-28     110     34     62GO:0005829; C:cytosol; TAS:Reactome.::GO:0030496; C:midbody; ISS:UniProtKB.::GO:0005886; C:plasma membrane; ISS:UniProtKB.
GO:0005525; F:GTP binding; ISS:UniProtKB.::GO:0003924; F:GTPase activity; ISS:UniProtKB.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0000910; P:cytokinesis; ISS:UniProtKB.::GO:0001928; P:regulation of exocyst assembly; IDA:UniProtKB.::GO:0060178; P:regulation of exocyst localization; IDA:UniProtKB.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
415Q9YH09    206   RALBA_XENLA Ras-related protein ralB-A OS=Xen...1866e-28     110     33     61GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.::GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0030036; P:actin cytoskeleton organization; IMP:UniProtKB.::GO:0008543; P:fibroblast growth factor receptor signaling pathway; IDA:UniProtKB.::GO:0007265; P:Ras protein signal transduction; IDA:UniProtKB.::GO:0048070; P:regulation of developmental pigmentation; IMP:UniProtKB.
416Q6IP71    206   RALBB_XENLA Ras-related protein ralB-B OS=Xen...1861e-27     109     33     61GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.
GO:0030036; P:actin cytoskeleton organization; ISS:UniProtKB.::GO:0008543; P:fibroblast growth factor receptor signaling pathway; ISS:UniProtKB.::GO:0007265; P:Ras protein signal transduction; ISS:UniProtKB.::GO:0048070; P:regulation of developmental pigmentation; ISS:UniProtKB.
417P48555    201   RALA_DROME Ras-related protein Ral-a OS=Droso...1811e-27     108     31     60GO:0005886; C:plasma membrane; IDA:FlyBase.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IDA:FlyBase.::GO:0030165; F:PDZ domain binding; IPI:FlyBase.
GO:0007298; P:border follicle cell migration; IMP:FlyBase.::GO:0007391; P:dorsal closure; NAS:FlyBase.::GO:0045087; P:innate immune response; IDA:FlyBase.::GO:0046329; P:negative regulation of JNK cascade; IGI:FlyBase.::GO:0007464; P:R3/R4 cell fate commitment; IMP:FlyBase.::GO:0022604; P:regulation of cell morphogenesis; IMP:FlyBase.::GO:0008593; P:regulation of Notch signaling pathway; IGI:FlyBase.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
418Q92963    219   RIT1_HUMAN GTP-binding protein Rit1 OS=Homo s...1842e-27     109     32     55GO:0005886; C:plasma membrane; TAS:ProtInc.
GO:0005516; F:calmodulin binding; TAS:ProtInc.::GO:0005525; F:GTP binding; TAS:ProtInc.::GO:0003924; F:GTPase activity; IEA:InterPro.
GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.
419P23175    189   RASH_MSVNS GTPase HRas OS=Murine sarcoma viru...1622e-27     108     33     59GO:0020002; C:host cell plasma membrane; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-KW.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
420Q8MXQ2    224   RB32C_DICDI Ras-related protein Rab-32C OS=Di...1713e-27     108     35     54
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0015031; P:protein transport; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
421P70426    219   RIT1_MOUSE GTP-binding protein Rit1 OS=Mus mu...1843e-27     108     31     57GO:0005886; C:plasma membrane; IDA:MGI.
GO:0005525; F:GTP binding; IDA:MGI.::GO:0003924; F:GTPase activity; IEA:InterPro.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
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