Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YFL005W
Length:
215
Number of sequences:
5887
Description:
YFL005W SEC4 SGDID:S000001889, Chr VI from 130334-130981, Genome Release 64-1-1, Verified ORF, "Rab family GTPase essential for vesicle-mediated exocytic secretion and autophagy; associates with the exocyst component Sec15p and may regulate polarized delivery of transport vesicles to the exocyst at the plasma membrane"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
361P36586    211   YPT5_SCHPO GTP-binding protein ypt5 OS=Schizo...1978e-34     125     39     57GO:0005829; C:cytosol; IDA:PomBase.::GO:0005770; C:late endosome; ISS:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IDA:PomBase.::GO:0003924; F:GTPase activity; ISS:PomBase.
GO:0006897; P:endocytosis; ISS:PomBase.::GO:0070314; P:G1 to G0 transition; IMP:PomBase.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0033157; P:regulation of intracellular protein transport; IC:PomBase.::GO:0031338; P:regulation of vesicle fusion; IMP:PomBase.::GO:0007264; P:small GTPase mediated signal transduction; IC:PomBase.
362Q96S21    281   RB40C_HUMAN Ras-related protein Rab-40C OS=Ho...1679e-34     127     41     62GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0015031; P:protein transport; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
363Q8VHQ4    281   RB40C_MOUSE Ras-related protein Rab-40C OS=Mu...1671e-33     127     41     62GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0015031; P:protein transport; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
364P31022    206   RAB7_PEA Ras-related protein Rab7 OS=Pisum sa...1681e-33     125     40     61GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
365P34142    212   RAB21_DICDI Ras-related protein Rab-21 OS=Dic...1592e-33     125     37     60GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.
GO:0030866; P:cortical actin cytoskeleton organization; IMP:dictyBase.::GO:0046847; P:filopodium assembly; IMP:dictyBase.::GO:0006909; P:phagocytosis; IEA:UniProtKB-KW.::GO:0050766; P:positive regulation of phagocytosis; IMP:dictyBase.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
366Q9ULC3    237   RAB23_HUMAN Ras-related protein Rab-23 OS=Hom...1982e-33     125     38     56GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
367O04157    203   RAG3B_ARATH Ras-related protein RABG3b OS=Ara...1692e-33     124     38     63GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0005773; C:vacuole; IDA:TAIR.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0048102; P:autophagic cell death; IMP:TAIR.::GO:0010623; P:developmental programmed cell death; IMP:TAIR.::GO:0010508; P:positive regulation of autophagy; IMP:UniProtKB.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.::GO:0010089; P:xylem development; IMP:UniProtKB.
368Q5JT25    222   RAB41_HUMAN Ras-related protein Rab-41 OS=Hom...1603e-33     124     39     64
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0015031; P:protein transport; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
369Q41640    206   RAB7_VIGAC Ras-related protein Rab7 OS=Vigna ...1683e-33     124     38     62GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
370O97572    207   RAB7A_RABIT Ras-related protein Rab-7a OS=Ory...1644e-33     124     38     62GO:0005770; C:late endosome; ISS:UniProtKB.::GO:0005764; C:lysosome; IEA:UniProtKB-SubCell.::GO:0042470; C:melanosome; IEA:UniProtKB-SubCell.::GO:0045335; C:phagocytic vesicle; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0045022; P:early endosome to late endosome transport; ISS:UniProtKB.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
371Q9LS94    206   RAG3F_ARATH Ras-related protein RABG3f OS=Ara...1685e-33     123     39     61GO:0005794; C:Golgi apparatus; IDA:TAIR.::GO:0005634; C:nucleus; IDA:TAIR.::GO:0005886; C:plasma membrane; IDA:TAIR.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
372Q7Z6P3    723   RAB44_HUMAN Ras-related protein Rab-44 OS=Hom...1889e-33     129     36     59GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0015031; P:protein transport; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
373O95755    333   RAB36_HUMAN Ras-related protein Rab-36 OS=Hom...2129e-33     125     35     54GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
374Q55E31    260   RB32B_DICDI Ras-related protein Rab-32B OS=Di...2041e-32     124     37     55
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0015031; P:protein transport; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
375Q5R7A4    203   RAB7L_PONAB Ras-related protein Rab-7L1 OS=Po...2061e-32     122     33     58GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
376O14966    203   RAB7L_HUMAN Ras-related protein Rab-7L1 OS=Ho...2061e-32     122     33     58GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; TAS:ProtInc.
GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
377Q40787    206   RAB7_CENCI Ras-related protein Rab7 OS=Cenchr...1682e-32     122     39     61GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
378Q20365    307   RAB33_CAEEL Ras-related protein Rab-33 OS=Cae...1912e-32     124     34     57GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0015031; P:protein transport; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
379Q5R9Y4    207   RAB7A_PONAB Ras-related protein Rab-7a OS=Pon...1642e-32     122     38     61GO:0005770; C:late endosome; ISS:UniProtKB.::GO:0005764; C:lysosome; IEA:UniProtKB-SubCell.::GO:0042470; C:melanosome; IEA:UniProtKB-SubCell.::GO:0045335; C:phagocytic vesicle; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0045022; P:early endosome to late endosome transport; ISS:UniProtKB.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
380P09527    207   RAB7A_RAT Ras-related protein Rab-7a OS=Rattu...1642e-32     122     38     61GO:0097208; C:alveolar lamellar body; IDA:RGD.::GO:0005770; C:late endosome; IDA:RGD.::GO:0005764; C:lysosome; IEA:UniProtKB-SubCell.::GO:0042470; C:melanosome; IEA:UniProtKB-SubCell.::GO:0045335; C:phagocytic vesicle; IEA:UniProtKB-SubCell.
GO:0019003; F:GDP binding; IDA:RGD.::GO:0005525; F:GTP binding; IDA:RGD.::GO:0003924; F:GTPase activity; TAS:RGD.::GO:0048365; F:Rac GTPase binding; IPI:RGD.
GO:0045453; P:bone resorption; IMP:RGD.::GO:0045022; P:early endosome to late endosome transport; ISS:UniProtKB.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
381P51150    207   RAB7A_MOUSE Ras-related protein Rab-7a OS=Mus...1642e-32     122     38     61GO:0005794; C:Golgi apparatus; IDA:MGI.::GO:0005770; C:late endosome; IDA:MGI.::GO:0005764; C:lysosome; IEA:UniProtKB-SubCell.::GO:0042470; C:melanosome; IEA:UniProtKB-SubCell.::GO:0045335; C:phagocytic vesicle; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0045022; P:early endosome to late endosome transport; ISS:UniProtKB.::GO:0006886; P:intracellular protein transport; TAS:MGI.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
382P51149    207   RAB7A_HUMAN Ras-related protein Rab-7a OS=Hom...1642e-32     122     38     61GO:0005794; C:Golgi apparatus; IDA:HPA.::GO:0005770; C:late endosome; IDA:UniProtKB.::GO:0005764; C:lysosome; IDA:MGI.::GO:0042470; C:melanosome; IEA:UniProtKB-SubCell.::GO:0045335; C:phagocytic vesicle; IEA:UniProtKB-SubCell.
GO:0019003; F:GDP binding; IDA:BHF-UCL.::GO:0005525; F:GTP binding; IDA:BHF-UCL.::GO:0003924; F:GTPase activity; IDA:BHF-UCL.::GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0045022; P:early endosome to late endosome transport; IMP:UniProtKB.::GO:0006897; P:endocytosis; TAS:ProtInc.::GO:0008333; P:endosome to lysosome transport; IMP:BHF-UCL.::GO:0007174; P:epidermal growth factor catabolic process; IMP:BHF-UCL.::GO:0090382; P:phagosome maturation; TAS:UniProtKB.::GO:0015031; P:protein transport; TAS:UniProtKB.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
383P36411    203   RAB7A_DICDI Ras-related protein Rab-7A OS=Dic...1652e-32     122     38     61GO:0005615; C:extracellular space; IDA:dictyBase.::GO:0005764; C:lysosome; IDA:dictyBase.::GO:0045335; C:phagocytic vesicle; IDA:dictyBase.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0006909; P:phagocytosis; IMP:dictyBase.::GO:0015031; P:protein transport; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
384P18067    207   RAB7A_CANFA Ras-related protein Rab-7a OS=Can...1642e-32     122     38     61GO:0005770; C:late endosome; ISS:UniProtKB.::GO:0005764; C:lysosome; IEA:UniProtKB-SubCell.::GO:0042470; C:melanosome; IEA:UniProtKB-SubCell.::GO:0045335; C:phagocytic vesicle; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0045022; P:early endosome to late endosome transport; IMP:UniProtKB.::GO:0007174; P:epidermal growth factor catabolic process; IMP:UniProtKB.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
385P36019    220   YPT53_YEAST GTP-binding protein YPT53 OS=Sacc...1672e-32     122     37     59GO:0005770; C:late endosome; IMP:SGD.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IDA:SGD.::GO:0005515; F:protein binding; IPI:IntAct.
GO:0006897; P:endocytosis; IMP:SGD.::GO:0006623; P:protein targeting to vacuole; IMP:SGD.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
386Q39573    206   YPTC5_CHLRE GTP-binding protein YPTC5 OS=Chla...2063e-32     121     33     57GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
387Q8CB87    725   RAB44_MOUSE Ras-related protein Rab-44 OS=Mus...1724e-32     127     37     58GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0015031; P:protein transport; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
388P36864    205   YPTV5_VOLCA GTP-binding protein yptV5 OS=Volv...1664e-32     121     39     61GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
389Q08DE8    200   RAB7B_BOVIN Ras-related protein Rab-7b OS=Bos...2025e-32     120     35     53GO:0005794; C:Golgi apparatus; ISS:UniProtKB.::GO:0005770; C:late endosome; ISS:UniProtKB.::GO:0005764; C:lysosome; ISS:UniProtKB.::GO:0005802; C:trans-Golgi network; ISS:UniProtKB.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0034499; P:late endosome to Golgi transport; ISS:UniProtKB.::GO:0034144; P:negative regulation of toll-like receptor 4 signaling pathway; ISS:UniProtKB.::GO:0034164; P:negative regulation of toll-like receptor 9 signaling pathway; ISS:UniProtKB.::GO:0032755; P:positive regulation of interleukin-6 production; ISS:UniProtKB.::GO:0045654; P:positive regulation of megakaryocyte differentiation; ISS:UniProtKB.::GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; ISS:UniProtKB.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
390Q86JC8    198   RABH_DICDI Ras-related protein RabH OS=Dictyo...1587e-32     120     39     61GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0015031; P:protein transport; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
391P93267    207   RAB7_MESCR Ras-related protein Rab7A OS=cryst...1678e-32     120     40     61GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
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