Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YFL005W
Length:
215
Number of sequences:
5887
Description:
YFL005W SEC4 SGDID:S000001889, Chr VI from 130334-130981, Genome Release 64-1-1, Verified ORF, "Rab family GTPase essential for vesicle-mediated exocytic secretion and autophagy; associates with the exocyst component Sec15p and may regulate polarized delivery of transport vesicles to the exocyst at the plasma membrane"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
271P61020    215   RAB5B_HUMAN Ras-related protein Rab-5B OS=Hom...2128e-41     144     36     59GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell.::GO:0042470; C:melanosome; IEA:UniProtKB-SubCell.::GO:0005624; C:membrane fraction; TAS:ProtInc.::GO:0005886; C:plasma membrane; TAS:ProtInc.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0030742; F:GTP-dependent protein binding; IDA:UniProtKB.::GO:0003924; F:GTPase activity; TAS:ProtInc.
GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
272P29687    200   RAB5_TOBAC Ras-related protein Rab5 OS=Nicoti...1951e-40     143     37     58GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
273Q9GP33    223   RAB4A_ECHMU Probable Ras-related protein Rab-...1931e-40     144     37     62GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
274Q9UL26    194   RB22A_HUMAN Ras-related protein Rab-22A OS=Ho...1611e-40     143     42     61GO:0005769; C:early endosome; IDA:UniProtKB.::GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IDA:UniProtKB.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; TAS:UniProtKB.::GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0006897; P:endocytosis; IDA:UniProtKB.::GO:0007032; P:endosome organization; IEP:UniProtKB.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
275Q5R7L7    216   RAB5C_PONAB Ras-related protein Rab-5C OS=Pon...1962e-40     143     38     59GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
276P51148    216   RAB5C_HUMAN Ras-related protein Rab-5C OS=Hom...1962e-40     143     38     59GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell.::GO:0005811; C:lipid particle; IDA:UniProtKB.::GO:0042470; C:melanosome; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; TAS:ProtInc.
GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
277Q5ZHW4    215   RAB5B_CHICK Ras-related protein Rab-5B OS=Gal...2112e-40     143     36     60GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
278P35282    222   RAB21_MOUSE Ras-related protein Rab-21 OS=Mus...2022e-40     143     38     55GO:0030659; C:cytoplasmic vesicle membrane; IEA:UniProtKB-SubCell.::GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell.::GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
GO:0019003; F:GDP binding; ISS:UniProtKB.::GO:0005525; F:GTP binding; ISS:UniProtKB.::GO:0003924; F:GTPase activity; ISS:UniProtKB.::GO:0005515; F:protein binding; IPI:IntAct.
GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
279Q9H082    229   RB33B_HUMAN Ras-related protein Rab-33B OS=Ho...2022e-40     143     38     58GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
280P51147    216   RAB5C_CANFA Ras-related protein Rab-5C OS=Can...1963e-40     142     38     59GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell.::GO:0042470; C:melanosome; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
281Q98932    216   RAB5C_CHICK Ras-related protein Rab-5C OS=Gal...1963e-40     142     38     58GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
282P17608    201   RYH1_SCHPO GTP-binding protein ryh1 OS=Schizo...1604e-40     142     43     68GO:0005829; C:cytosol; IDA:PomBase.::GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IDA:PomBase.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; TAS:PomBase.::GO:0003924; F:GTPase activity; ISS:PomBase.
GO:0071470; P:cellular response to osmotic stress; IMP:PomBase.::GO:0006886; P:intracellular protein transport; ISS:PomBase.::GO:0042147; P:retrograde transport, endosome to Golgi; ISS:PomBase.::GO:0007264; P:small GTPase mediated signal transduction; IC:PomBase.
283P35278    216   RAB5C_MOUSE Ras-related protein Rab-5C OS=Mus...1964e-40     142     38     59GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell.::GO:0030139; C:endocytic vesicle; IDA:MGI.::GO:0042470; C:melanosome; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; TAS:MGI.::GO:0005515; F:protein binding; IPI:MGI.
GO:0007032; P:endosome organization; IDA:MGI.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0030100; P:regulation of endocytosis; IDA:MGI.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
284Q5RI75    627   RASEF_MOUSE Ras and EF-hand domain-containing...2066e-40     148     38     62GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0015031; P:protein transport; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
285P51154    194   RB22A_CANFA Ras-related protein Rab-22A OS=Ca...1726e-40     141     41     59GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
286Q5R615    229   RB33B_PONAB Ras-related protein Rab-33B OS=Po...2021e-39     141     37     58GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
287Q9CB01    202   RABF1_ARATH Ras-related protein RABF1 OS=Arab...1691e-39     140     40     64GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell.::GO:0010009; C:external side of endosome membrane; IDA:TAIR.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IDA:TAIR.::GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0045022; P:early endosome to late endosome transport; IMP:TAIR.::GO:0006897; P:endocytosis; IEA:UniProtKB-KW.::GO:0015031; P:protein transport; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
288P36017    210   VPS21_YEAST Vacuolar protein sorting-associat...2021e-39     140     37     60GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.::GO:0005770; C:late endosome; IMP:SGD.::GO:0005741; C:mitochondrial outer membrane; IDA:SGD.
GO:0005525; F:GTP binding; IDA:SGD.::GO:0003924; F:GTPase activity; IDA:SGD.::GO:0005515; F:protein binding; IPI:IntAct.
GO:0006897; P:endocytosis; IMP:SGD.::GO:0006623; P:protein targeting to vacuole; IMP:SGD.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.::GO:0000011; P:vacuole inheritance; IMP:SGD.
289Q55FK2    208   RAB6_DICDI Ras-related protein Rab-6 OS=Dicty...2041e-39     140     39     60
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
290Q9CQD1    215   RAB5A_MOUSE Ras-related protein Rab-5A OS=Mus...1962e-39     140     36     58GO:0015629; C:actin cytoskeleton; IDA:MGI.::GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell.::GO:0030139; C:endocytic vesicle; IDA:MGI.::GO:0042470; C:melanosome; IEA:UniProtKB-SubCell.::GO:0045121; C:membrane raft; IDA:MGI.::GO:0005886; C:plasma membrane; IDA:MGI.::GO:0001726; C:ruffle; IDA:MGI.
GO:0019003; F:GDP binding; ISS:UniProtKB.::GO:0005525; F:GTP binding; ISS:UniProtKB.::GO:0003924; F:GTPase activity; ISS:UniProtKB.::GO:0005515; F:protein binding; IPI:MGI.
GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0007399; P:nervous system development; IEA:UniProtKB-KW.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
291Q13636    194   RAB31_HUMAN Ras-related protein Rab-31 OS=Hom...1952e-39     139     35     58GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; TAS:ProtInc.
GO:0015031; P:protein transport; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
292Q17R06    222   RAB21_BOVIN Ras-related protein Rab-21 OS=Bos...1632e-39     140     42     63GO:0030659; C:cytoplasmic vesicle membrane; IEA:UniProtKB-SubCell.::GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell.::GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
GO:0019003; F:GDP binding; ISS:UniProtKB.::GO:0005525; F:GTP binding; ISS:UniProtKB.::GO:0003924; F:GTPase activity; ISS:UniProtKB.
GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
293Q9UL25    225   RAB21_HUMAN Ras-related protein Rab-21 OS=Hom...2033e-39     140     37     56GO:0032154; C:cleavage furrow; IEA:UniProtKB-SubCell.::GO:0030659; C:cytoplasmic vesicle membrane; IEA:UniProtKB-SubCell.::GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell.::GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
GO:0019003; F:GDP binding; IDA:UniProtKB.::GO:0005525; F:GTP binding; IDA:UniProtKB.::GO:0003924; F:GTPase activity; IDA:UniProtKB.::GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
294Q06AU6    215   RAB5A_PIG Ras-related protein Rab-5A OS=Sus s...1963e-39     140     36     59GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell.::GO:0042470; C:melanosome; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0019003; F:GDP binding; ISS:UniProtKB.::GO:0005525; F:GTP binding; ISS:UniProtKB.::GO:0003924; F:GTPase activity; ISS:UniProtKB.
GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0006897; P:endocytosis; ISS:UniProtKB.::GO:0007399; P:nervous system development; IEA:UniProtKB-KW.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
295P61271    215   RAB5A_MACFA Ras-related protein Rab-5A OS=Mac...1964e-39     139     36     59GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell.::GO:0042470; C:melanosome; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0019003; F:GDP binding; ISS:UniProtKB.::GO:0005525; F:GTP binding; ISS:UniProtKB.::GO:0003924; F:GTPase activity; ISS:UniProtKB.
GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0006897; P:endocytosis; ISS:UniProtKB.::GO:0007399; P:nervous system development; IEA:UniProtKB-KW.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
296P18066    215   RAB5A_CANFA Ras-related protein Rab-5A OS=Can...1964e-39     139     36     59GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell.::GO:0005811; C:lipid particle; IDA:UniProtKB.::GO:0042470; C:melanosome; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0019003; F:GDP binding; ISS:UniProtKB.::GO:0005525; F:GTP binding; ISS:UniProtKB.::GO:0003924; F:GTPase activity; ISS:UniProtKB.
GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0007399; P:nervous system development; IEA:UniProtKB-KW.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
297Q6AXT5    223   RAB21_RAT Ras-related protein Rab-21 OS=Rattu...1634e-39     140     42     63GO:0030659; C:cytoplasmic vesicle membrane; IEA:UniProtKB-SubCell.::GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell.::GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
GO:0019003; F:GDP binding; ISS:UniProtKB.::GO:0005525; F:GTP binding; ISS:UniProtKB.::GO:0003924; F:GTPase activity; ISS:UniProtKB.
GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
298Q9SMR4    214   RAH1C_ARATH Ras-related protein RABH1c OS=Ara...1594e-39     139     43     67GO:0005829; C:cytosol; IDA:UniProtKB.::GO:0000139; C:Golgi membrane; IDA:UniProtKB.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:TAIR.
GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.::GO:0016192; P:vesicle-mediated transport; IEA:UniProtKB-KW.
299Q6GQP4    194   RAB31_RAT Ras-related protein Rab-31 OS=Rattu...1965e-39     139     36     58GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0048193; P:Golgi vesicle transport; IMP:RGD.::GO:0015031; P:protein transport; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
300P55745    223   RAB21_CANFA Ras-related protein Rab-21 OS=Can...1637e-39     139     42     63GO:0030659; C:cytoplasmic vesicle membrane; IEA:UniProtKB-SubCell.::GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell.::GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
GO:0019003; F:GDP binding; ISS:UniProtKB.::GO:0005525; F:GTP binding; ISS:UniProtKB.::GO:0003924; F:GTPase activity; ISS:UniProtKB.
GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
301Q921E2    194   RAB31_MOUSE Ras-related protein Rab-31 OS=Mus...1958e-39     138     36     57GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0015031; P:protein transport; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
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