Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YFL005W
Length:
215
Number of sequences:
5887
Description:
YFL005W SEC4 SGDID:S000001889, Chr VI from 130334-130981, Genome Release 64-1-1, Verified ORF, "Rab family GTPase essential for vesicle-mediated exocytic secretion and autophagy; associates with the exocyst component Sec15p and may regulate polarized delivery of transport vesicles to the exocyst at the plasma membrane"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
181Q52NJ6    215   RAB14_PIG Ras-related protein Rab-14 OS=Sus s...1743e-48     163     44     64GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
GO:0019003; F:GDP binding; ISS:UniProtKB.::GO:0005525; F:GTP binding; ISS:UniProtKB.::GO:0003924; F:GTPase activity; ISS:UniProtKB.
GO:0009790; P:embryo development; ISS:UniProtKB.::GO:0008543; P:fibroblast growth factor receptor signaling pathway; ISS:UniProtKB.::GO:0006895; P:Golgi to endosome transport; ISS:UniProtKB.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
182Q558I0    190   RABF1_DICDI Ras-related protein RabF1 OS=Dict...1913e-48     162     43     63GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0015031; P:protein transport; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
183Q8MXS1    203   RAB18_CAEEL Ras-related protein Rab-18 OS=Cae...1734e-48     162     48     66GO:0005622; C:intracellular; IEA:InterPro.
GO:0005524; F:ATP binding; IEA:InterPro.::GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0008134; F:transcription factor binding; IEA:InterPro.
GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0040022; P:feminization of hermaphroditic germ-line; IMP:WormBase.::GO:0007281; P:germ cell development; IMP:WormBase.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0042127; P:regulation of cell proliferation; IMP:WormBase.::GO:0040020; P:regulation of meiosis; IMP:WormBase.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
184O00194    218   RB27B_HUMAN Ras-related protein Rab-27B OS=Ho...1824e-48     163     44     66GO:0005795; C:Golgi stack; IDA:UniProtKB.::GO:0032585; C:multivesicular body membrane; IDA:UniProtKB.::GO:0030140; C:trans-Golgi network transport vesicle; IDA:UniProtKB.
GO:0005525; F:GTP binding; ISS:UniProtKB.::GO:0003924; F:GTPase activity; ISS:UniProtKB.::GO:0019904; F:protein domain specific binding; IPI:UniProtKB.
GO:0071985; P:multivesicular body sorting pathway; IMP:UniProtKB.::GO:0045921; P:positive regulation of exocytosis; IMP:UniProtKB.::GO:0015031; P:protein transport; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
185Q01111    218   YPT3_NICPL Ras-related protein YPT3 OS=Nicoti...2084e-48     163     43     63GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
186P35293    206   RAB18_MOUSE Ras-related protein Rab-18 OS=Mus...1665e-48     162     51     67GO:0016324; C:apical plasma membrane; IEA:UniProtKB-SubCell.::GO:0009925; C:basal plasma membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:InterPro.::GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0008134; F:transcription factor binding; IEA:InterPro.
GO:0007420; P:brain development; ISS:UniProtKB.::GO:0001654; P:eye development; ISS:UniProtKB.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
187Q5EB77    206   RAB18_RAT Ras-related protein Rab-18 OS=Rattu...1666e-48     162     51     67
GO:0005524; F:ATP binding; IEA:InterPro.::GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0008134; F:transcription factor binding; IEA:InterPro.
GO:0007420; P:brain development; ISS:UniProtKB.::GO:0001654; P:eye development; ISS:UniProtKB.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
188Q5R5H5    206   RAB18_PONAB Ras-related protein Rab-18 OS=Pon...1667e-48     162     51     67
GO:0005524; F:ATP binding; IEA:InterPro.::GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0008134; F:transcription factor binding; IEA:InterPro.
GO:0007420; P:brain development; ISS:UniProtKB.::GO:0001654; P:eye development; ISS:UniProtKB.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
189Q9NP72    206   RAB18_HUMAN Ras-related protein Rab-18 OS=Hom...1667e-48     162     51     67GO:0005622; C:intracellular; IDA:LIFEdb.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:InterPro.::GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; NAS:UniProtKB.::GO:0008134; F:transcription factor binding; IEA:InterPro.
GO:0007420; P:brain development; ISS:UniProtKB.::GO:0006897; P:endocytosis; NAS:UniProtKB.::GO:0001654; P:eye development; ISS:UniProtKB.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; NAS:UniProtKB.
190Q1HE58    221   RB27A_CANFA Ras-related protein Rab-27A OS=Ca...1817e-48     162     44     67GO:0005764; C:lysosome; IEA:UniProtKB-SubCell.::GO:0042470; C:melanosome; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; ISS:UniProtKB.::GO:0003924; F:GTPase activity; ISS:UniProtKB.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
191Q0WQN4    229   RAA6B_ARATH Ras-related protein RABA6b OS=Ara...2178e-48     162     41     59GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
192Q0IIG8    206   RAB18_BOVIN Ras-related protein Rab-18 OS=Bos...1668e-48     162     51     67GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:InterPro.::GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0008134; F:transcription factor binding; IEA:InterPro.
GO:0007420; P:brain development; ISS:UniProtKB.::GO:0001654; P:eye development; ISS:UniProtKB.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
193P36412    214   RB11A_DICDI Ras-related protein Rab-11A OS=Di...2201e-47     162     39     61GO:0031164; C:contractile vacuolar membrane; IDA:UniProtKB.::GO:0045335; C:phagocytic vesicle; IDA:dictyBase.
GO:0005525; F:GTP binding; IDA:UniProtKB.::GO:0032794; F:GTPase activating protein binding; IPI:dictyBase.
GO:0007231; P:osmosensory signaling pathway; IMP:UniProtKB.::GO:0034394; P:protein localization at cell surface; IMP:dictyBase.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IDA:UniProtKB.
194Q99P58    218   RB27B_MOUSE Ras-related protein Rab-27B OS=Mu...1811e-47     162     45     67
GO:0005525; F:GTP binding; IDA:UniProtKB.::GO:0003924; F:GTPase activity; IDA:UniProtKB.
GO:0015031; P:protein transport; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
195Q99P74    218   RB27B_RAT Ras-related protein Rab-27B OS=Ratt...1811e-47     162     45     67GO:0016324; C:apical plasma membrane; IDA:RGD.::GO:0042589; C:zymogen granule membrane; IDA:RGD.
GO:0005525; F:GTP binding; ISS:UniProtKB.::GO:0003924; F:GTPase activity; ISS:UniProtKB.
GO:0015031; P:protein transport; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
196P23640    221   RB27A_RAT Ras-related protein Rab-27A OS=Ratt...1811e-47     162     43     67GO:0016324; C:apical plasma membrane; IDA:RGD.::GO:0005764; C:lysosome; IEA:UniProtKB-SubCell.::GO:0042470; C:melanosome; IEA:UniProtKB-SubCell.::GO:0030667; C:secretory granule membrane; IDA:RGD.
GO:0005525; F:GTP binding; ISS:UniProtKB.::GO:0003924; F:GTPase activity; ISS:UniProtKB.::GO:0019904; F:protein domain specific binding; IPI:UniProtKB.
GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
197Q40195    218   RB11E_LOTJA Ras-related protein Rab11E OS=Lot...2082e-47     161     41     62GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0015031; P:protein transport; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
198Q8HZJ5    218   RB27B_BOVIN Ras-related protein Rab-27B OS=Bo...1822e-47     161     43     66
GO:0005525; F:GTP binding; ISS:UniProtKB.::GO:0003924; F:GTPase activity; ISS:UniProtKB.
GO:0015031; P:protein transport; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
199Q9C9U7    233   RAA6A_ARATH Ras-related protein RABA6a OS=Ara...1682e-47     161     48     67GO:0005886; C:plasma membrane; IDA:TAIR.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
200Q9ERI2    221   RB27A_MOUSE Ras-related protein Rab-27A OS=Mu...1812e-47     161     43     66GO:0005829; C:cytosol; TAS:Reactome.::GO:0005794; C:Golgi apparatus; IDA:MGI.::GO:0005764; C:lysosome; IEA:UniProtKB-SubCell.::GO:0042470; C:melanosome; IDA:UniProtKB.::GO:0001750; C:photoreceptor outer segment; IDA:UniProtKB.
GO:0005525; F:GTP binding; IDA:UniProtKB.::GO:0003924; F:GTPase activity; IDA:UniProtKB.::GO:0031489; F:myosin V binding; IPI:MGI.
GO:0007596; P:blood coagulation; IMP:MGI.::GO:0043316; P:cytotoxic T cell degranulation; IMP:MGI.::GO:0030318; P:melanocyte differentiation; IMP:MGI.::GO:0032402; P:melanosome transport; IMP:MGI.::GO:0043320; P:natural killer cell degranulation; IMP:MGI.::GO:0006605; P:protein targeting; IMP:MGI.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
201Q40523    216   RB11A_TOBAC Ras-related protein Rab11A OS=Nic...2094e-47     160     41     61GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0015031; P:protein transport; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
202P25766    226   RLGP1_ORYSJ Ras-related protein RGP1 OS=Oryza...2134e-47     160     38     60GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0015031; P:protein transport; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
203Q9FJN8    226   RAA4A_ARATH Ras-related protein RABA4a OS=Ara...2097e-47     160     40     61GO:0005886; C:plasma membrane; IDA:TAIR.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
204Q40194    218   RB11D_LOTJA Ras-related protein Rab11D OS=Lot...2089e-47     159     41     61GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0015031; P:protein transport; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
205Q40522    222   RB11D_TOBAC Ras-related protein Rab11D OS=Nic...2191e-46     159     38     59GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0015031; P:protein transport; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
206Q68EK7    213   RAB4B_DANRE Ras-related protein Rab-4B OS=Dan...2091e-46     159     40     58GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
207P61018    213   RAB4B_HUMAN Ras-related protein Rab-4B OS=Hom...1771e-46     159     44     64GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; NAS:UniProtKB.
GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.::GO:0016192; P:vesicle-mediated transport; NAS:UniProtKB.
208P61017    213   RAB4B_CANFA Ras-related protein Rab-4B OS=Can...1771e-46     159     44     64GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
209P51146    213   RAB4B_RAT Ras-related protein Rab-4B OS=Rattu...1931e-46     159     43     64GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
210Q91ZR1    213   RAB4B_MOUSE Ras-related protein Rab-4B OS=Mus...1931e-46     159     43     64GO:0005739; C:mitochondrion; IDA:MGI.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
211P46629    213   RAB25_RABIT Ras-related protein Rab-25 OS=Ory...2152e-46     158     40     60GO:0031410; C:cytoplasmic vesicle; ISS:UniProtKB.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0031143; C:pseudopodium; ISS:UniProtKB.
GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
GO:0008284; P:positive regulation of cell proliferation; ISS:UniProtKB.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0031268; P:pseudopodium organization; ISS:UniProtKB.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
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