UniProt_SwissProt BLAST: Single locus

Species:

Saccharomyces cerevisiae S288C

Locus:

YFL005W

Length:

215

Number of sequences:

5887

Description:

YFL005W SEC4 SGDID:S000001889, Chr VI from 130334-130981, Genome Release 64-1-1, Verified ORF, "Rab family GTPase essential for vesicle-mediated exocytic secretion and autophagy; associates with the exocyst component Sec15p and may regulate polarized delivery of transport vesicles to the exocyst at the plasma membrane"

rec.	Subject	Hit Length	Description	Align.Len	E value	Bit score	% ident.	% pos.	GO associations
151	P34143	196	RABC_DICDI Ras-related protein RabC OS=Dictyo...	199	3e-51	171	43	67	GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
									GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0019901; F:protein kinase binding; IPI:dictyBase.
									GO:0015031; P:protein transport; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
152	P36409	207	RAB2A_DICDI Ras-related protein Rab-2A OS=Dic...	169	5e-51	170	47	67	GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
									GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
									GO:0015031; P:protein transport; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
153	P35284	197	RAB12_RAT Ras-related protein Rab-12 OS=Rattu...	161	6e-51	169	51	75	GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0030141; C:secretory granule; IDA:RGD.
									GO:0005525; F:GTP binding; TAS:RGD.
									GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
154	Q40723	217	RLGP2_ORYSJ Ras-related protein RGP2 OS=Oryza...	210	6e-51	170	41	64	GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
									GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
									GO:0015031; P:protein transport; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
155	Q9LNW1	214	RAA2B_ARATH Ras-related protein RABA2b OS=Ara...	204	8e-51	170	42	63	GO:0009504; C:cell plate; IDA:TAIR.::GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.::GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IDA:TAIR.
									GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
									GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
156	P38555	223	YPT31_YEAST GTP-binding protein YPT31/YPT8 OS...	177	2e-50	169	44	69	GO:0005768; C:endosome; IDA:SGD.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0005741; C:mitochondrial outer membrane; IDA:SGD.
									GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IDA:SGD.::GO:0005515; F:protein binding; IPI:IntAct.
									GO:0034498; P:early endosome to Golgi transport; IGI:SGD.::GO:0006887; P:exocytosis; IMP:SGD.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
157	P22129	218	RB11B_DISOM Ras-related protein Rab-11B OS=Di...	158	2e-50	169	48	72	GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
									GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
									GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
158	P46638	218	RB11B_MOUSE Ras-related protein Rab-11B OS=Mu...	158	4e-50	168	48	71	GO:0005739; C:mitochondrion; IDA:MGI.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
									GO:0019003; F:GDP binding; ISS:UniProtKB.::GO:0005525; F:GTP binding; ISS:UniProtKB.::GO:0003924; F:GTPase activity; ISS:UniProtKB.
									GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
159	O49841	210	RAC2A_ARATH Ras-related protein RABC2a OS=Ara...	176	4e-50	168	53	66	GO:0005777; C:peroxisome; IDA:TAIR.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
									GO:0005524; F:ATP binding; IEA:InterPro.::GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0030742; F:GTP-dependent protein binding; IPI:TAIR.::GO:0080115; F:myosin XI tail binding; IPI:TAIR.::GO:0008134; F:transcription factor binding; IEA:InterPro.
									GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
160	O35509	218	RB11B_RAT Ras-related protein Rab-11B OS=Ratt...	158	4e-50	168	48	71	GO:0016023; C:cytoplasmic membrane-bounded vesicle; IDA:MGI.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
									GO:0019003; F:GDP binding; ISS:UniProtKB.::GO:0005525; F:GTP binding; ISS:UniProtKB.::GO:0003924; F:GTPase activity; ISS:UniProtKB.
									GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0006928; P:cellular component movement; NAS:RGD.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
161	Q15907	218	RB11B_HUMAN Ras-related protein Rab-11B OS=Ho...	158	4e-50	168	48	71	GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
									GO:0019003; F:GDP binding; IDA:UniProtKB.::GO:0005525; F:GTP binding; IDA:UniProtKB.::GO:0003924; F:GTPase activity; IDA:UniProtKB.
									GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
162	Q3MHP2	218	RB11B_BOVIN Ras-related protein Rab-11B OS=Bo...	158	4e-50	168	48	71	GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
									GO:0019003; F:GDP binding; ISS:UniProtKB.::GO:0005525; F:GTP binding; ISS:UniProtKB.::GO:0003924; F:GTPase activity; ISS:UniProtKB.
									GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
163	P51996	222	YPT32_YEAST GTP-binding protein YPT32/YPT11 O...	216	5e-50	168	42	60	GO:0005768; C:endosome; IDA:SGD.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0005741; C:mitochondrial outer membrane; IDA:SGD.
									GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IDA:SGD.::GO:0005515; F:protein binding; IPI:IntAct.
									GO:0034498; P:early endosome to Golgi transport; IGI:SGD.::GO:0006887; P:exocytosis; IMP:SGD.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
164	Q9SRS5	217	RAA5B_ARATH Ras-related protein RABA5b OS=Ara...	212	2e-49	166	43	66	GO:0005886; C:plasma membrane; IDA:TAIR.
									GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
									GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
165	P28187	214	RAA5C_ARATH Ras-related protein RABA5c OS=Ara...	177	4e-49	165	44	69	GO:0005829; C:cytosol; IDA:TAIR.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0005795; C:Golgi stack; IDA:TAIR.::GO:0005798; C:Golgi-associated vesicle; IDA:TAIR.::GO:0005886; C:plasma membrane; IDA:TAIR.::GO:0005802; C:trans-Golgi network; IDA:TAIR.
									GO:0005525; F:GTP binding; IDA:UniProtKB.::GO:0003924; F:GTPase activity; IDA:UniProtKB.
									GO:0048219; P:inter-Golgi cisterna vesicle-mediated transport; TAS:TAIR.::GO:0015031; P:protein transport; IEA:InterPro.::GO:0009408; P:response to heat; IEP:TAIR.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
166	Q39222	216	RAA1B_ARATH Ras-related protein RABA1b OS=Ara...	190	6e-49	165	45	66	GO:0005886; C:plasma membrane; IDA:TAIR.::GO:0005774; C:vacuolar membrane; IDA:TAIR.
									GO:0005525; F:GTP binding; IDA:TAIR.
									GO:0006886; P:intracellular protein transport; TAS:TAIR.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
167	Q39572	216	YPTC6_CHLRE Ras-related protein YPTC6 OS=Chla...	210	7e-49	165	41	62	GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
									GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
									GO:0015031; P:protein transport; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
168	Q9FIF9	217	RAA2D_ARATH Ras-related protein RABA2d OS=Ara...	212	1e-48	164	41	60	GO:0009504; C:cell plate; IDA:TAIR.::GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.::GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IDA:TAIR.
									GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
									GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
169	Q96283	217	RAA2C_ARATH Ras-related protein RABA2c OS=Ara...	163	1e-48	164	46	70	GO:0009504; C:cell plate; IDA:TAIR.::GO:0005829; C:cytosol; IDA:TAIR.::GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.::GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IDA:TAIR.::GO:0009506; C:plasmodesma; IDA:TAIR.
									GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
									GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
170	Q9SMQ6	224	RAA4B_ARATH Ras-related protein RABA4b OS=Ara...	207	1e-48	164	41	60	GO:0031901; C:early endosome membrane; IDA:UniProtKB.::GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IDA:TAIR.::GO:0032588; C:trans-Golgi network membrane; IDA:UniProtKB.
									GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0019900; F:kinase binding; IPI:UniProtKB.
									GO:0032456; P:endocytic recycling; IDA:TAIR.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
171	Q5ZLG1	206	RAB18_CHICK Ras-related protein Rab-18 OS=Gal...	187	2e-48	164	48	64
									GO:0005524; F:ATP binding; IEA:InterPro.::GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0008134; F:transcription factor binding; IEA:InterPro.
									GO:0007420; P:brain development; ISS:UniProtKB.::GO:0001654; P:eye development; ISS:UniProtKB.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
172	Q4LE85	221	RB27A_PIG Ras-related protein Rab-27A OS=Sus ...	181	2e-48	164	45	67	GO:0005764; C:lysosome; IEA:UniProtKB-SubCell.::GO:0042470; C:melanosome; IEA:UniProtKB-SubCell.
									GO:0005525; F:GTP binding; ISS:UniProtKB.::GO:0003924; F:GTPase activity; ISS:UniProtKB.
									GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
173	P51159	221	RB27A_HUMAN Ras-related protein Rab-27A OS=Ho...	181	2e-48	164	44	68	GO:0030425; C:dendrite; IDA:UniProtKB.::GO:0070382; C:exocytic vesicle; IDA:UniProtKB.::GO:0005764; C:lysosome; IDA:UniProtKB.::GO:0042470; C:melanosome; IDA:UniProtKB.::GO:0032585; C:multivesicular body membrane; IDA:UniProtKB.
									GO:0005525; F:GTP binding; ISS:UniProtKB.::GO:0003924; F:GTPase activity; ISS:UniProtKB.
									GO:0071985; P:multivesicular body sorting pathway; IMP:UniProtKB.::GO:0045921; P:positive regulation of exocytosis; IMP:UniProtKB.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
174	Q6DHC1	205	RB18B_DANRE Ras-related protein Rab-18-B OS=D...	164	2e-48	163	50	68	GO:0005622; C:intracellular; IEA:InterPro.
									GO:0005524; F:ATP binding; IEA:InterPro.::GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0008134; F:transcription factor binding; IEA:InterPro.
									GO:0007420; P:brain development; IMP:UniProtKB.::GO:0009790; P:embryo development; IMP:ZFIN.::GO:0001654; P:eye development; IMP:UniProtKB.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
175	P90726	202	RAB18_CAEBR Ras-related protein Rab-18 OS=Cae...	173	2e-48	163	48	66	GO:0005622; C:intracellular; IEA:InterPro.
									GO:0005524; F:ATP binding; IEA:InterPro.::GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0008134; F:transcription factor binding; IEA:InterPro.
									GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
176	Q5R8Z8	215	RAB14_PONAB Ras-related protein Rab-14 OS=Pon...	174	2e-48	163	44	64	GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
									GO:0019003; F:GDP binding; ISS:UniProtKB.::GO:0005525; F:GTP binding; ISS:UniProtKB.::GO:0003924; F:GTPase activity; ISS:UniProtKB.
									GO:0009790; P:embryo development; ISS:UniProtKB.::GO:0008543; P:fibroblast growth factor receptor signaling pathway; ISS:UniProtKB.::GO:0006895; P:Golgi to endosome transport; ISS:UniProtKB.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
177	Q91V41	215	RAB14_MOUSE Ras-related protein Rab-14 OS=Mus...	174	2e-48	163	44	64	GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
									GO:0019003; F:GDP binding; ISS:UniProtKB.::GO:0005525; F:GTP binding; ISS:UniProtKB.::GO:0003924; F:GTPase activity; ISS:UniProtKB.
									GO:0009790; P:embryo development; IMP:UniProtKB.::GO:0008543; P:fibroblast growth factor receptor signaling pathway; IMP:UniProtKB.::GO:0006895; P:Golgi to endosome transport; IMP:UniProtKB.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
178	P61106	215	RAB14_HUMAN Ras-related protein Rab-14 OS=Hom...	174	2e-48	163	44	64	GO:0005829; C:cytosol; ISS:UniProtKB.::GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0005795; C:Golgi stack; ISS:UniProtKB.::GO:0005770; C:late endosome; ISS:UniProtKB.::GO:0005764; C:lysosome; ISS:UniProtKB.::GO:0005624; C:membrane fraction; ISS:UniProtKB.::GO:0042175; C:nuclear outer membrane-endoplasmic reticulum membrane network; ISS:UniProtKB.::GO:0048471; C:perinuclear region of cytoplasm; ISS:UniProtKB.::GO:0005791; C:rough endoplasmic reticulum; ISS:UniProtKB.::GO:0030140; C:trans-Golgi network transport vesicle; ISS:UniProtKB.
									GO:0019003; F:GDP binding; IDA:UniProtKB.::GO:0005525; F:GTP binding; IDA:UniProtKB.::GO:0003924; F:GTPase activity; IDA:UniProtKB.
									GO:0009790; P:embryo development; ISS:UniProtKB.::GO:0008543; P:fibroblast growth factor receptor signaling pathway; ISS:UniProtKB.::GO:0006895; P:Golgi to endosome transport; ISS:UniProtKB.::GO:0007269; P:neurotransmitter secretion; NAS:UniProtKB.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; NAS:UniProtKB.
179	Q5ZKU5	215	RAB14_CHICK Ras-related protein Rab-14 OS=Gal...	174	2e-48	163	44	64	GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
									GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
									GO:0009790; P:embryo development; ISS:UniProtKB.::GO:0008543; P:fibroblast growth factor receptor signaling pathway; ISS:UniProtKB.::GO:0006895; P:Golgi to endosome transport; ISS:UniProtKB.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
180	P61107	215	RAB14_RAT Ras-related protein Rab-14 OS=Rattu...	174	3e-48	163	44	64	GO:0097208; C:alveolar lamellar body; IDA:RGD.::GO:0016324; C:apical plasma membrane; IDA:RGD.::GO:0005829; C:cytosol; IDA:UniProtKB.::GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0005795; C:Golgi stack; IDA:UniProtKB.::GO:0005770; C:late endosome; IDA:UniProtKB.::GO:0005764; C:lysosome; IDA:UniProtKB.::GO:0005624; C:membrane fraction; IDA:UniProtKB.::GO:0042175; C:nuclear outer membrane-endoplasmic reticulum membrane network; IDA:UniProtKB.::GO:0048471; C:perinuclear region of cytoplasm; IDA:UniProtKB.::GO:0005791; C:rough endoplasmic reticulum; IDA:UniProtKB.::GO:0030140; C:trans-Golgi network transport vesicle; IDA:UniProtKB.
									GO:0019003; F:GDP binding; ISS:UniProtKB.::GO:0001948; F:glycoprotein binding; IDA:RGD.::GO:0005525; F:GTP binding; ISS:UniProtKB.::GO:0003924; F:GTPase activity; ISS:UniProtKB.
									GO:0045176; P:apical protein localization; IDA:RGD.::GO:0007589; P:body fluid secretion; IMP:RGD.::GO:0009790; P:embryo development; ISS:UniProtKB.::GO:0008543; P:fibroblast growth factor receptor signaling pathway; ISS:UniProtKB.::GO:0006895; P:Golgi to endosome transport; ISS:UniProtKB.::GO:0007269; P:neurotransmitter secretion; NAS:UniProtKB.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0032880; P:regulation of protein localization; IDA:RGD.::GO:0007264; P:small GTPase mediated signal transduction; NAS:UniProtKB.
181	Q52NJ6	215	RAB14_PIG Ras-related protein Rab-14 OS=Sus s...	174	3e-48	163	44	64	GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell.::GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
									GO:0019003; F:GDP binding; ISS:UniProtKB.::GO:0005525; F:GTP binding; ISS:UniProtKB.::GO:0003924; F:GTPase activity; ISS:UniProtKB.
									GO:0009790; P:embryo development; ISS:UniProtKB.::GO:0008543; P:fibroblast growth factor receptor signaling pathway; ISS:UniProtKB.::GO:0006895; P:Golgi to endosome transport; ISS:UniProtKB.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.

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