UniProt_SwissProt BLAST: Single locus

Species:

Saccharomyces cerevisiae S288C

Locus:

YFL003C

Length:

878

Number of sequences:

5887

Description:

YFL003C MSH4 SGDID:S000001891, Chr VI from 137157-134521, Genome Release 64-1-1, reverse complement, Verified ORF, "Protein involved in meiotic recombination, required for normal levels of crossing over, colocalizes with Zip2p to discrete foci on meiotic chromosomes, has homology to bacterial MutS protein"

rec.	Subject	Hit Length	Description	Align.Len	E value	Bit score	% ident.	% pos.	GO associations
631	Q4FV41	1058	MUTS_PSYA2 DNA mismatch repair protein MutS O...	604	1e-26	121	23	42
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0030983; F:mismatched DNA binding; IEA:InterPro.
									GO:0006298; P:mismatch repair; IEA:InterPro.
632	P43248	917	MSH2_DROME DNA mismatch repair protein spellc...	737	1e-26	120	23	44	GO:0032301; C:MutSalpha complex; IBA:RefGenome.::GO:0032302; C:MutSbeta complex; IBA:RefGenome.::GO:0000228; C:nuclear chromosome; IBA:RefGenome.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003684; F:damaged DNA binding; IBA:RefGenome.::GO:0008094; F:DNA-dependent ATPase activity; IBA:RefGenome.::GO:0000406; F:double-strand/single-strand DNA junction binding; IBA:RefGenome.::GO:0000400; F:four-way junction DNA binding; IBA:RefGenome.::GO:0032137; F:guanine/thymine mispair binding; IBA:RefGenome.::GO:0000404; F:loop DNA binding; IBA:RefGenome.::GO:0032138; F:single base insertion or deletion binding; IBA:RefGenome.::GO:0000403; F:Y-form DNA binding; IBA:RefGenome.
									GO:0042771; P:DNA damage response, signal transduction by p53 class mediator resulting in induction of apoptosis; IBA:RefGenome.::GO:0006302; P:double-strand break repair; IBA:RefGenome.::GO:0031573; P:intra-S DNA damage checkpoint; IBA:RefGenome.::GO:0043570; P:maintenance of DNA repeat elements; IMP:FlyBase.::GO:0006311; P:meiotic gene conversion; IBA:RefGenome.::GO:0000710; P:meiotic mismatch repair; IBA:RefGenome.::GO:0045128; P:negative regulation of reciprocal meiotic recombination; IBA:RefGenome.::GO:0006301; P:postreplication repair; ISS:UniProtKB.::GO:0010224; P:response to UV-B; IBA:RefGenome.::GO:0010165; P:response to X-ray; IBA:RefGenome.
633	Q4US90	873	MUTS_XANC8 DNA mismatch repair protein MutS O...	587	1e-26	120	26	46
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0030983; F:mismatched DNA binding; IEA:InterPro.
									GO:0006298; P:mismatch repair; IEA:InterPro.
634	Q8PBB5	891	MUTS_XANCP DNA mismatch repair protein MutS O...	587	2e-26	120	26	46
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0030983; F:mismatched DNA binding; IEA:InterPro.
									GO:0006298; P:mismatch repair; IEA:InterPro.
635	Q2IIJ3	882	MUTS_ANADE DNA mismatch repair protein MutS O...	112	0.0004	47.8	35	50
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0030983; F:mismatched DNA binding; IEA:InterPro.
									GO:0006298; P:mismatch repair; IEA:InterPro.
636	B8JA66	882	MUTS_ANAD2 DNA mismatch repair protein MutS O...	112	0.00002	52	37	52
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0030983; F:mismatched DNA binding; IEA:InterPro.
									GO:0006298; P:mismatch repair; IEA:InterPro.
637	Q6MG62	831	MSH5_RAT MutS protein homolog 5 OS=Rattus nor...	579	2e-26	119	23	46	GO:0000795; C:synaptonemal complex; IBA:RefGenome.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008094; F:DNA-dependent ATPase activity; IBA:RefGenome.::GO:0030983; F:mismatched DNA binding; IBA:RefGenome.
									GO:0051026; P:chiasma assembly; IBA:RefGenome.::GO:0045143; P:homologous chromosome segregation; IBA:RefGenome.::GO:0006298; P:mismatch repair; IEA:InterPro.::GO:0007131; P:reciprocal meiotic recombination; IBA:RefGenome.
638	B4UCY7	882	MUTS_ANASK DNA mismatch repair protein MutS O...	112	0.00002	52	37	52
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0030983; F:mismatched DNA binding; IEA:InterPro.
									GO:0006298; P:mismatch repair; IEA:InterPro.
639	O04716	1324	MSH6_ARATH DNA mismatch repair protein Msh6-1...	769	8e-26	118	23	42
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003684; F:damaged DNA binding; IDA:TAIR.::GO:0030983; F:mismatched DNA binding; IEA:InterPro.
									GO:0006298; P:mismatch repair; ISS:TAIR.::GO:0006290; P:pyrimidine dimer repair; IMP:TAIR.
640	Q7UA23	900	MUTS_SYNPX DNA mismatch repair protein MutS O...	534	9e-26	117	25	44
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0030983; F:mismatched DNA binding; IEA:InterPro.
									GO:0006298; P:mismatch repair; IEA:InterPro.
641	A1WXK9	868	MUTS_HALHL DNA mismatch repair protein MutS O...	549	1e-25	117	24	44
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0030983; F:mismatched DNA binding; IEA:InterPro.
									GO:0006298; P:mismatch repair; IEA:InterPro.
642	P52701	1360	MSH6_HUMAN DNA mismatch repair protein Msh6 O...	729	1e-25	117	23	41	GO:0032301; C:MutSalpha complex; IDA:HGNC.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008094; F:DNA-dependent ATPase activity; IBA:RefGenome.::GO:0005515; F:protein binding; IPI:UniProtKB.
									GO:0008340; P:determination of adult lifespan; ISS:BHF-UCL.::GO:0008630; P:DNA damage response, signal transduction resulting in induction of apoptosis; ISS:BHF-UCL.::GO:0045190; P:isotype switching; ISS:BHF-UCL.::GO:0000710; P:meiotic mismatch repair; ISS:BHF-UCL.::GO:0045910; P:negative regulation of DNA recombination; IDA:BHF-UCL.::GO:0051096; P:positive regulation of helicase activity; IDA:BHF-UCL.::GO:0007131; P:reciprocal meiotic recombination; IBA:RefGenome.::GO:0009411; P:response to UV; ISS:BHF-UCL.::GO:0016446; P:somatic hypermutation of immunoglobulin genes; ISS:BHF-UCL.
643	Q5B6T1	1105	MSH3_EMENI DNA mismatch repair protein msh3 O...	259	2e-25	117	32	53	GO:0032302; C:MutSbeta complex; IBA:RefGenome.::GO:0000228; C:nuclear chromosome; IBA:RefGenome.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003684; F:damaged DNA binding; IBA:RefGenome.::GO:0008094; F:DNA-dependent ATPase activity; IBA:RefGenome.::GO:0000406; F:double-strand/single-strand DNA junction binding; IBA:RefGenome.::GO:0000404; F:loop DNA binding; IBA:RefGenome.::GO:0000403; F:Y-form DNA binding; IBA:RefGenome.
									GO:0043570; P:maintenance of DNA repeat elements; IBA:RefGenome.::GO:0000710; P:meiotic mismatch repair; IBA:RefGenome.::GO:0007131; P:reciprocal meiotic recombination; IBA:RefGenome.::GO:0000735; P:removal of nonhomologous ends; IBA:RefGenome.
644	P25847	964	MSH2_YEAST DNA mismatch repair protein MSH2 O...	601	2e-25	117	24	45	GO:0032301; C:MutSalpha complex; IPI:SGD.::GO:0032302; C:MutSbeta complex; IPI:SGD.::GO:0000228; C:nuclear chromosome; IDA:SGD.
									GO:0005524; F:ATP binding; IDA:SGD.::GO:0003684; F:damaged DNA binding; IBA:RefGenome.::GO:0008094; F:DNA-dependent ATPase activity; IBA:RefGenome.::GO:0000406; F:double-strand/single-strand DNA junction binding; IDA:SGD.::GO:0000400; F:four-way junction DNA binding; IDA:SGD.::GO:0030983; F:mismatched DNA binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct.
									GO:0030466; P:chromatin silencing at silent mating-type cassette; IGI:SGD.::GO:0043570; P:maintenance of DNA repeat elements; IBA:RefGenome.::GO:0006311; P:meiotic gene conversion; IMP:SGD.::GO:0000710; P:meiotic mismatch repair; IMP:SGD.::GO:0045128; P:negative regulation of reciprocal meiotic recombination; IBA:RefGenome.::GO:0006301; P:postreplication repair; IBA:RefGenome.::GO:0000735; P:removal of nonhomologous ends; IMP:SGD.
645	P0CO92	1191	MSH3_CRYNJ DNA mismatch repair protein MSH3 O...	319	0.0000000008	66.6	24	43	GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0030983; F:mismatched DNA binding; IEA:InterPro.
									GO:0006298; P:mismatch repair; IEA:InterPro.
646	P0CO93	1191	MSH3_CRYNB DNA mismatch repair protein MSH3 O...	319	0.000000001	66.2	24	43	GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0030983; F:mismatched DNA binding; IEA:InterPro.
									GO:0006298; P:mismatch repair; IEA:InterPro.
647	P54276	1358	MSH6_MOUSE DNA mismatch repair protein Msh6 O...	736	3e-25	116	24	42	GO:0032301; C:MutSalpha complex; IDA:MGI.::GO:0000790; C:nuclear chromatin; IDA:MGI.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003682; F:chromatin binding; IDA:MGI.::GO:0008094; F:DNA-dependent ATPase activity; IBA:RefGenome.::GO:0000400; F:four-way junction DNA binding; IBA:RefGenome.::GO:0032137; F:guanine/thymine mispair binding; IDA:MGI.
									GO:0008340; P:determination of adult lifespan; IMP:MGI.::GO:0008630; P:DNA damage response, signal transduction resulting in induction of apoptosis; IMP:MGI.::GO:0045190; P:isotype switching; IMP:MGI.::GO:0043570; P:maintenance of DNA repeat elements; IBA:RefGenome.::GO:0000710; P:meiotic mismatch repair; IBA:RefGenome.::GO:0045910; P:negative regulation of DNA recombination; IMP:MGI.::GO:0007131; P:reciprocal meiotic recombination; IBA:RefGenome.::GO:0009411; P:response to UV; IMP:MGI.::GO:0016446; P:somatic hypermutation of immunoglobulin genes; IMP:MGI.
648	Q3ANH5	903	MUTS_SYNSC DNA mismatch repair protein MutS O...	283	6e-25	115	29	51
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0030983; F:mismatched DNA binding; IEA:InterPro.
									GO:0006298; P:mismatch repair; IEA:InterPro.
649	A3LU10	1025	MSH3_PICST DNA mismatch repair protein MSH3 O...	765	6e-25	115	23	46	GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0030983; F:mismatched DNA binding; IEA:InterPro.
									GO:0006298; P:mismatch repair; IEA:InterPro.
650	P25846	959	MSH1_YEAST DNA mismatch repair protein MSH1, ...	735	8e-25	115	24	41	GO:0032300; C:mismatch repair complex; IBA:RefGenome.::GO:0005739; C:mitochondrion; IDA:SGD.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003684; F:damaged DNA binding; IBA:RefGenome.::GO:0032139; F:dinucleotide insertion or deletion binding; IDA:SGD.::GO:0008094; F:DNA-dependent ATPase activity; IDA:SGD.::GO:0032137; F:guanine/thymine mispair binding; IDA:SGD.
									GO:0006298; P:mismatch repair; IMP:SGD.::GO:0043504; P:mitochondrial DNA repair; IMP:SGD.
651	A6RPB6	1133	MSH3_BOTFB DNA mismatch repair protein msh3 O...	289	0.00000001	62.8	24	43	GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0030983; F:mismatched DNA binding; IEA:InterPro.
									GO:0006298; P:mismatch repair; IEA:InterPro.
652	O13921	941	MSH1_SCHPO MutS protein homolog 1 OS=Schizosa...	764	2e-23	110	24	43	GO:0032300; C:mismatch repair complex; ISS:RefGenome.::GO:0005739; C:mitochondrion; IDA:PomBase.::GO:0000228; C:nuclear chromosome; ISS:RefGenome.
									GO:0005524; F:ATP binding; ISS:PomBase.::GO:0003684; F:damaged DNA binding; ISS:RefGenome.::GO:0032139; F:dinucleotide insertion or deletion binding; ISS:RefGenome.::GO:0008094; F:DNA-dependent ATPase activity; ISS:PomBase.::GO:0032137; F:guanine/thymine mispair binding; ISS:RefGenome.::GO:0000404; F:loop DNA binding; ISS:RefGenome.
									GO:0043570; P:maintenance of DNA repeat elements; ISS:RefGenome.::GO:0000710; P:meiotic mismatch repair; ISS:RefGenome.::GO:0043504; P:mitochondrial DNA repair; ISS:PomBase.::GO:0007131; P:reciprocal meiotic recombination; ISS:RefGenome.
653	Q9VUM0	1190	MSH6_DROME Probable DNA mismatch repair prote...	663	3e-23	110	23	41	GO:0032301; C:MutSalpha complex; IBA:RefGenome.::GO:0000228; C:nuclear chromosome; IBA:RefGenome.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003684; F:damaged DNA binding; IBA:RefGenome.::GO:0008094; F:DNA-dependent ATPase activity; IBA:RefGenome.::GO:0000400; F:four-way junction DNA binding; IBA:RefGenome.::GO:0032137; F:guanine/thymine mispair binding; IBA:RefGenome.::GO:0032138; F:single base insertion or deletion binding; IBA:RefGenome.
									GO:0008630; P:DNA damage response, signal transduction resulting in induction of apoptosis; IBA:RefGenome.::GO:0043570; P:maintenance of DNA repeat elements; IBA:RefGenome.::GO:0000710; P:meiotic mismatch repair; IMP:FlyBase.::GO:0045910; P:negative regulation of DNA recombination; IBA:RefGenome.::GO:0007131; P:reciprocal meiotic recombination; IBA:RefGenome.::GO:0009411; P:response to UV; IBA:RefGenome.
654	Q9K8A0	785	MUTS2_BACHD MutS2 protein OS=9153 / C-125). G...	208	2e-22	107	32	54
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003684; F:damaged DNA binding; IEA:InterPro.::GO:0030983; F:mismatched DNA binding; IEA:InterPro.
									GO:0045005; P:maintenance of fidelity involved in DNA-dependent DNA replication; IEA:InterPro.::GO:0006298; P:mismatch repair; IEA:InterPro.
655	Q59Y41	1037	MSH3_CANAL DNA mismatch repair protein MSH3 O...	301	4e-22	106	28	51	GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0030983; F:mismatched DNA binding; IEA:InterPro.
									GO:0006298; P:mismatch repair; IEA:InterPro.
656	O74502	1254	MSH6_SCHPO DNA mismatch repair protein msh6 O...	293	0.00003	51.6	22	43	GO:0005829; C:cytosol; IDA:PomBase.::GO:0032301; C:MutSalpha complex; ISS:RefGenome.::GO:0000228; C:nuclear chromosome; ISS:RefGenome.
									GO:0005524; F:ATP binding; ISS:PomBase.::GO:0003684; F:damaged DNA binding; ISS:RefGenome.::GO:0008094; F:DNA-dependent ATPase activity; ISS:RefGenome.::GO:0000400; F:four-way junction DNA binding; ISS:RefGenome.::GO:0032137; F:guanine/thymine mispair binding; ISS:PomBase.::GO:0032138; F:single base insertion or deletion binding; ISS:RefGenome.
									GO:0043570; P:maintenance of DNA repeat elements; IMP:PomBase.::GO:0000710; P:meiotic mismatch repair; ISS:RefGenome.::GO:0045910; P:negative regulation of DNA recombination; ISS:RefGenome.::GO:0007131; P:reciprocal meiotic recombination; ISS:RefGenome.::GO:0009411; P:response to UV; ISS:RefGenome.
657	Q5WEK0	787	MUTS2_BACSK MutS2 protein OS=Bacillus clausii...	208	5e-21	102	30	53
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003684; F:damaged DNA binding; IEA:InterPro.::GO:0030983; F:mismatched DNA binding; IEA:InterPro.
									GO:0045005; P:maintenance of fidelity involved in DNA-dependent DNA replication; IEA:InterPro.::GO:0006298; P:mismatch repair; IEA:InterPro.
658	C5D5Q8	784	MUTS2_GEOSW MutS2 protein OS=Geobacillus sp. ...	224	1e-19	98.2	30	53
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003684; F:damaged DNA binding; IEA:InterPro.::GO:0030983; F:mismatched DNA binding; IEA:InterPro.
									GO:0045005; P:maintenance of fidelity involved in DNA-dependent DNA replication; IEA:InterPro.::GO:0006298; P:mismatch repair; IEA:InterPro.
659	Q5FLW2	785	MUTS2_LACAC MutS2 protein OS=Lactobacillus ac...	212	2e-19	97.4	30	57
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003684; F:damaged DNA binding; IEA:InterPro.::GO:0030983; F:mismatched DNA binding; IEA:InterPro.
									GO:0045005; P:maintenance of fidelity involved in DNA-dependent DNA replication; IEA:InterPro.::GO:0006298; P:mismatch repair; IEA:InterPro.
660	A4IRL1	784	MUTS2_GEOTN MutS2 protein OS=Geobacillus ther...	242	2e-19	97.1	30	48
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003684; F:damaged DNA binding; IEA:InterPro.::GO:0030983; F:mismatched DNA binding; IEA:InterPro.
									GO:0045005; P:maintenance of fidelity involved in DNA-dependent DNA replication; IEA:InterPro.::GO:0006298; P:mismatch repair; IEA:InterPro.
661	A7Z7E7	785	MUTS2_BACA2 MutS2 protein OS=Bacillus amyloli...	220	2e-19	97.1	32	51
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003684; F:damaged DNA binding; IEA:InterPro.::GO:0030983; F:mismatched DNA binding; IEA:InterPro.
									GO:0045005; P:maintenance of fidelity involved in DNA-dependent DNA replication; IEA:InterPro.::GO:0006298; P:mismatch repair; IEA:InterPro.

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