Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YER178W
Length:
420
Number of sequences:
5887
Description:
YER178W PDA1 SGDID:S000000980, Chr V from 546817-548079, Genome Release 64-1-1, Verified ORF, "E1 alpha subunit of the pyruvate dehydrogenase (PDH) complex, catalyzes the direct oxidative decarboxylation of pyruvate to acetyl-CoA; phosphorylated; regulated by glucose"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
61Q54JE4    1013   ODO1_DICDI 2-oxoglutarate dehydrogenase, mito...1360.00005     49.3     29     47GO:0009353; C:mitochondrial oxoglutarate dehydrogenase complex; ISS:dictyBase.
GO:0004591; F:oxoglutarate dehydrogenase (succinyl-transferring) activity; IEA:EC.::GO:0030976; F:thiamine pyrophosphate binding; IEA:InterPro.
GO:0006096; P:glycolysis; IEA:UniProtKB-KW.::GO:0006099; P:tricarboxylic acid cycle; IEA:InterPro.
62Q623T0    1027   ODO1_CAEBR 2-oxoglutarate dehydrogenase, mito...2260.0001     48.1     26     41GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell.::GO:0031966; C:mitochondrial membrane; ISS:UniProtKB.
GO:0004591; F:oxoglutarate dehydrogenase (succinyl-transferring) activity; ISS:UniProtKB.::GO:0030976; F:thiamine pyrophosphate binding; IEA:InterPro.
GO:0006096; P:glycolysis; IEA:UniProtKB-KW.::GO:0006099; P:tricarboxylic acid cycle; IEA:InterPro.
63O61199    1029   ODO1_CAEEL 2-oxoglutarate dehydrogenase, mito...2260.0002     47.8     26     41GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell.::GO:0031966; C:mitochondrial membrane; ISS:UniProtKB.
GO:0004591; F:oxoglutarate dehydrogenase (succinyl-transferring) activity; ISS:UniProtKB.::GO:0030976; F:thiamine pyrophosphate binding; IEA:InterPro.
GO:0008340; P:determination of adult lifespan; IMP:WormBase.::GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0006096; P:glycolysis; IEA:UniProtKB-KW.::GO:0040007; P:growth; IMP:WormBase.::GO:0002119; P:nematode larval development; IMP:WormBase.::GO:0040010; P:positive regulation of growth rate; IMP:WormBase.::GO:0006099; P:tricarboxylic acid cycle; IEA:InterPro.
64P23129    944   ODO1_BACSU 2-oxoglutarate dehydrogenase E1 co...1680.0003     47     27     44
GO:0004591; F:oxoglutarate dehydrogenase (succinyl-transferring) activity; IEA:EC.::GO:0030976; F:thiamine pyrophosphate binding; IEA:InterPro.
GO:0006096; P:glycolysis; IEA:UniProtKB-KW.::GO:0006099; P:tricarboxylic acid cycle; IEA:InterPro.
65P20707    943   ODO1_AZOVI 2-oxoglutarate dehydrogenase E1 co...1180.0003     46.6     29     47
GO:0004591; F:oxoglutarate dehydrogenase (succinyl-transferring) activity; IEA:EC.::GO:0030976; F:thiamine pyrophosphate binding; IEA:InterPro.
GO:0006096; P:glycolysis; IEA:UniProtKB-KW.::GO:0006099; P:tricarboxylic acid cycle; IEA:InterPro.
66Q9VA02    919   DHTK1_DROME Probable 2-oxoglutarate dehydroge...1810.0003     46.6     26     42GO:0031966; C:mitochondrial membrane; ISS:UniProtKB.
GO:0004591; F:oxoglutarate dehydrogenase (succinyl-transferring) activity; ISS:UniProtKB.::GO:0030976; F:thiamine pyrophosphate binding; IEA:InterPro.
GO:0006096; P:glycolysis; IEA:UniProtKB-KW.::GO:0006099; P:tricarboxylic acid cycle; IEA:InterPro.
67O74378    1009   ODO1_SCHPO 2-oxoglutarate dehydrogenase, mito...1920.0005     46.2     26     43GO:0042645; C:mitochondrial nucleoid; ISS:PomBase.::GO:0009353; C:mitochondrial oxoglutarate dehydrogenase complex; ISS:PomBase.
GO:0004591; F:oxoglutarate dehydrogenase (succinyl-transferring) activity; IEA:EC.::GO:0030976; F:thiamine pyrophosphate binding; IEA:InterPro.
GO:0006103; P:2-oxoglutarate metabolic process; ISS:PomBase.::GO:0006099; P:tricarboxylic acid cycle; ISS:PomBase.
68Q9CC97    1238   KGD_MYCLE 2-oxoglutarate decarboxylase OS=Myc...2700.002     44.7     27     38
GO:0008683; F:2-oxoglutarate decarboxylase activity; IEA:EC.::GO:0004591; F:oxoglutarate dehydrogenase (succinyl-transferring) activity; IEA:InterPro.::GO:0030976; F:thiamine pyrophosphate binding; IEA:InterPro.::GO:0016746; F:transferase activity, transferring acyl groups; IEA:InterPro.
GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW.
69A8FE66    944   ODO1_BACP2 2-oxoglutarate dehydrogenase E1 co...1220.002     44.3     30     47
GO:0004591; F:oxoglutarate dehydrogenase (succinyl-transferring) activity; IEA:EC.::GO:0030976; F:thiamine pyrophosphate binding; IEA:InterPro.
GO:0006096; P:glycolysis; IEA:UniProtKB-KW.::GO:0006099; P:tricarboxylic acid cycle; IEA:InterPro.
70Q148N0    1023   ODO1_BOVIN 2-oxoglutarate dehydrogenase, mito...1620.002     44.3     28     43GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell.
GO:0004591; F:oxoglutarate dehydrogenase (succinyl-transferring) activity; IEA:EC.::GO:0030976; F:thiamine pyrophosphate binding; IEA:InterPro.
GO:0006096; P:glycolysis; IEA:UniProtKB-KW.::GO:0006099; P:tricarboxylic acid cycle; IEA:InterPro.
71Q5RCB8    1023   ODO1_PONAB 2-oxoglutarate dehydrogenase, mito...1620.002     44.3     28     43GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell.::GO:0031966; C:mitochondrial membrane; ISS:UniProtKB.
GO:0004591; F:oxoglutarate dehydrogenase (succinyl-transferring) activity; ISS:UniProtKB.::GO:0030976; F:thiamine pyrophosphate binding; IEA:InterPro.
GO:0006096; P:glycolysis; IEA:UniProtKB-KW.::GO:0006099; P:tricarboxylic acid cycle; IEA:InterPro.
72Q02218    1023   ODO1_HUMAN 2-oxoglutarate dehydrogenase, mito...1620.002     44.3     28     43GO:0005759; C:mitochondrial matrix; TAS:Reactome.::GO:0031966; C:mitochondrial membrane; ISS:UniProtKB.::GO:0005739; C:mitochondrion; IDA:HPA.
GO:0004591; F:oxoglutarate dehydrogenase (succinyl-transferring) activity; ISS:UniProtKB.::GO:0030976; F:thiamine pyrophosphate binding; IEA:InterPro.
GO:0006096; P:glycolysis; IEA:UniProtKB-KW.::GO:0006554; P:lysine catabolic process; TAS:Reactome.::GO:0006099; P:tricarboxylic acid cycle; TAS:Reactome.
73Q60HE2    1023   ODO1_MACFA 2-oxoglutarate dehydrogenase, mito...1620.002     44.3     28     43GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell.::GO:0031966; C:mitochondrial membrane; ISS:UniProtKB.
GO:0004591; F:oxoglutarate dehydrogenase (succinyl-transferring) activity; ISS:UniProtKB.::GO:0030976; F:thiamine pyrophosphate binding; IEA:InterPro.
GO:0006096; P:glycolysis; IEA:UniProtKB-KW.::GO:0006099; P:tricarboxylic acid cycle; IEA:InterPro.
74Q5XI78    1023   ODO1_RAT 2-oxoglutarate dehydrogenase, mitoch...1620.002     43.9     28     43GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell.::GO:0031966; C:mitochondrial membrane; ISS:UniProtKB.::GO:0045252; C:oxoglutarate dehydrogenase complex; IDA:RGD.
GO:0051087; F:chaperone binding; IPI:RGD.::GO:0031072; F:heat shock protein binding; IPI:RGD.::GO:0004591; F:oxoglutarate dehydrogenase (succinyl-transferring) activity; ISS:UniProtKB.::GO:0030976; F:thiamine pyrophosphate binding; IEA:InterPro.
GO:0006103; P:2-oxoglutarate metabolic process; IDA:RGD.::GO:0006096; P:glycolysis; IEA:UniProtKB-KW.::GO:0006734; P:NADH metabolic process; IDA:RGD.::GO:0006104; P:succinyl-CoA metabolic process; IDA:RGD.::GO:0006099; P:tricarboxylic acid cycle; IDA:RGD.
75Q60597    1023   ODO1_MOUSE 2-oxoglutarate dehydrogenase, mito...1620.002     43.9     28     43GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell.::GO:0031966; C:mitochondrial membrane; ISS:UniProtKB.
GO:0034602; F:oxoglutarate dehydrogenase (NAD+) activity; IDA:MGI.::GO:0004591; F:oxoglutarate dehydrogenase (succinyl-transferring) activity; ISS:UniProtKB.::GO:0030976; F:thiamine pyrophosphate binding; IEA:InterPro.
GO:0021695; P:cerebellar cortex development; IEP:UniProtKB.::GO:0006096; P:glycolysis; IEA:UniProtKB-KW.::GO:0021766; P:hippocampus development; IEP:UniProtKB.::GO:0061034; P:olfactory bulb mitral cell layer development; IEP:UniProtKB.::GO:0021860; P:pyramidal neuron development; IEP:UniProtKB.::GO:0021756; P:striatum development; IEP:UniProtKB.::GO:0022028; P:tangential migration from the subventricular zone to the olfactory bulb; IEP:UniProtKB.::GO:0021794; P:thalamus development; IEP:UniProtKB.::GO:0006099; P:tricarboxylic acid cycle; IEA:InterPro.
76Q1RHI4    927   ODO1_RICBR 2-oxoglutarate dehydrogenase E1 co...1360.003     43.5     31     48
GO:0004591; F:oxoglutarate dehydrogenase (succinyl-transferring) activity; IEA:EC.::GO:0030976; F:thiamine pyrophosphate binding; IEA:InterPro.
GO:0006096; P:glycolysis; IEA:UniProtKB-KW.::GO:0006099; P:tricarboxylic acid cycle; IEA:InterPro.
77Q8F6S7    920   ODO1_LEPIN 2-oxoglutarate dehydrogenase E1 co...1100.005     43.1     30     45
GO:0004591; F:oxoglutarate dehydrogenase (succinyl-transferring) activity; IEA:EC.::GO:0030976; F:thiamine pyrophosphate binding; IEA:InterPro.
GO:0006096; P:glycolysis; IEA:UniProtKB-KW.::GO:0006099; P:tricarboxylic acid cycle; IEA:InterPro.
78Q72PJ7    920   ODO1_LEPIC 2-oxoglutarate dehydrogenase E1 co...1100.005     43.1     30     45
GO:0004591; F:oxoglutarate dehydrogenase (succinyl-transferring) activity; IEA:EC.::GO:0030976; F:thiamine pyrophosphate binding; IEA:InterPro.
GO:0006096; P:glycolysis; IEA:UniProtKB-KW.::GO:0006099; P:tricarboxylic acid cycle; IEA:InterPro.
79Q68XI7    933   ODO1_RICTY 2-oxoglutarate dehydrogenase E1 co...1100.005     42.7     34     51
GO:0004591; F:oxoglutarate dehydrogenase (succinyl-transferring) activity; IEA:EC.::GO:0030976; F:thiamine pyrophosphate binding; IEA:InterPro.
GO:0006096; P:glycolysis; IEA:UniProtKB-KW.::GO:0006099; P:tricarboxylic acid cycle; IEA:InterPro.
80A7Z5J9    944   ODO1_BACA2 2-oxoglutarate dehydrogenase E1 co...1200.007     42.4     29     46
GO:0004591; F:oxoglutarate dehydrogenase (succinyl-transferring) activity; IEA:EC.::GO:0030976; F:thiamine pyrophosphate binding; IEA:InterPro.
GO:0006096; P:glycolysis; IEA:UniProtKB-KW.::GO:0006099; P:tricarboxylic acid cycle; IEA:InterPro.
81Q6P286    927   DHTK1_XENLA Probable 2-oxoglutarate dehydroge...2060.008     42.4     22     42GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.
GO:0004591; F:oxoglutarate dehydrogenase (succinyl-transferring) activity; IEA:EC.::GO:0030976; F:thiamine pyrophosphate binding; IEA:InterPro.
GO:0006096; P:glycolysis; IEA:UniProtKB-KW.::GO:0006099; P:tricarboxylic acid cycle; IEA:InterPro.
82O50463    1231   KGD_MYCTU 2-oxoglutarate decarboxylase OS=Myc...1170.008     42.4     32     44GO:0005886; C:plasma membrane; IDA:MTBBASE.::GO:0045254; C:pyruvate dehydrogenase complex; IDA:MTBBASE.
GO:0008683; F:2-oxoglutarate decarboxylase activity; IDA:MTBBASE.::GO:0009055; F:electron carrier activity; IDA:MTBBASE.::GO:0000287; F:magnesium ion binding; IDA:MTBBASE.::GO:0016624; F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor; IEA:InterPro.::GO:0005515; F:protein binding; IPI:MTBBASE.::GO:0030976; F:thiamine pyrophosphate binding; IEA:InterPro.::GO:0016746; F:transferase activity, transferring acyl groups; IEA:InterPro.
GO:0040007; P:growth; IMP:MTBBASE.::GO:0006099; P:tricarboxylic acid cycle; IDA:MTBBASE.
83A5U1U6    1231   KGD_MYCTA 2-oxoglutarate decarboxylase OS=Myc...1170.008     42.4     32     44
GO:0008683; F:2-oxoglutarate decarboxylase activity; IEA:EC.::GO:0004591; F:oxoglutarate dehydrogenase (succinyl-transferring) activity; IEA:InterPro.::GO:0030976; F:thiamine pyrophosphate binding; IEA:InterPro.::GO:0016746; F:transferase activity, transferring acyl groups; IEA:InterPro.
GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW.
84A1KI36    1231   KGD_MYCBP 2-oxoglutarate decarboxylase OS=Myc...1170.009     42.4     32     44
GO:0008683; F:2-oxoglutarate decarboxylase activity; IEA:EC.::GO:0004591; F:oxoglutarate dehydrogenase (succinyl-transferring) activity; IEA:InterPro.::GO:0030976; F:thiamine pyrophosphate binding; IEA:InterPro.::GO:0016746; F:transferase activity, transferring acyl groups; IEA:InterPro.
GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW.
85Q7U0A6    1231   KGD_MYCBO 2-oxoglutarate decarboxylase OS=Myc...1170.009     42.4     32     44
GO:0008683; F:2-oxoglutarate decarboxylase activity; IEA:EC.::GO:0004591; F:oxoglutarate dehydrogenase (succinyl-transferring) activity; IEA:InterPro.::GO:0030976; F:thiamine pyrophosphate binding; IEA:InterPro.::GO:0016746; F:transferase activity, transferring acyl groups; IEA:InterPro.
GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW.
86Q8XX95    636   DXS_RALSO 1-deoxy-D-xylulose-5-phosphate synt...1110.011     41.6     29     46
GO:0008661; F:1-deoxy-D-xylulose-5-phosphate synthase activity; IEA:EC.
GO:0016114; P:terpenoid biosynthetic process; IEA:InterPro.::GO:0009228; P:thiamine biosynthetic process; IEA:UniProtKB-KW.
87Q6P6Z8    1021   ODO1_XENLA 2-oxoglutarate dehydrogenase, mito...1620.012     41.6     28     42GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell.
GO:0004591; F:oxoglutarate dehydrogenase (succinyl-transferring) activity; IEA:EC.::GO:0030976; F:thiamine pyrophosphate binding; IEA:InterPro.
GO:0006096; P:glycolysis; IEA:UniProtKB-KW.::GO:0006099; P:tricarboxylic acid cycle; IEA:InterPro.
88Q9ZDY3    936   ODO1_RICPR 2-oxoglutarate dehydrogenase E1 co...1100.014     41.6     33     51
GO:0004591; F:oxoglutarate dehydrogenase (succinyl-transferring) activity; IEA:EC.::GO:0030976; F:thiamine pyrophosphate binding; IEA:InterPro.
GO:0006096; P:glycolysis; IEA:UniProtKB-KW.::GO:0006099; P:tricarboxylic acid cycle; IEA:InterPro.
89Q5R9L8    1010   OGDHL_PONAB 2-oxoglutarate dehydrogenase-like...1410.018     41.2     29     43GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell.
GO:0004591; F:oxoglutarate dehydrogenase (succinyl-transferring) activity; IEA:InterPro.::GO:0030976; F:thiamine pyrophosphate binding; IEA:InterPro.
GO:0006096; P:glycolysis; IEA:UniProtKB-KW.::GO:0006099; P:tricarboxylic acid cycle; IEA:InterPro.
90Q9ULD0    1010   OGDHL_HUMAN 2-oxoglutarate dehydrogenase-like...1410.018     41.2     29     43GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell.
GO:0004591; F:oxoglutarate dehydrogenase (succinyl-transferring) activity; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0030976; F:thiamine pyrophosphate binding; IEA:InterPro.
GO:0006096; P:glycolysis; IEA:UniProtKB-KW.::GO:0006099; P:tricarboxylic acid cycle; IEA:InterPro.
91Q5WG56    943   ODO1_BACSK 2-oxoglutarate dehydrogenase E1 co...1200.021     40.8     31     46
GO:0004591; F:oxoglutarate dehydrogenase (succinyl-transferring) activity; IEA:EC.::GO:0030976; F:thiamine pyrophosphate binding; IEA:InterPro.
GO:0006096; P:glycolysis; IEA:UniProtKB-KW.::GO:0006099; P:tricarboxylic acid cycle; IEA:InterPro.
records
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