Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
Home About FGC Use Cases Species List

UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YER174C
Length:
244
Number of sequences:
5887
Description:
YER174C GRX4 SGDID:S000000976, Chr V from 539168-538434, Genome Release 64-1-1, reverse complement, Verified ORF, "Hydroperoxide and superoxide-radical responsive glutathione-dependent oxidoreductase; monothiol glutaredoxin subfamily member along with Grx3p and Grx5p; protects cells from oxidative damage; mutant has increased aneuploidy tolerance"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
1P32642    244   GLRX4_YEAST Monothiol glutaredoxin-4 OS=Sacch...2441e-179     500     100     100GO:0005634; C:nucleus; IGI:SGD.
GO:0051537; F:2 iron, 2 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
GO:0030036; P:actin cytoskeleton organization; IMP:SGD.::GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0006879; P:cellular iron ion homeostasis; IGI:SGD.::GO:0034599; P:cellular response to oxidative stress; IMP:SGD.
2Q03835    285   GLRX3_YEAST Monothiol glutaredoxin-3 OS=Sacch...2494e-112     330     66     80GO:0005829; C:cytosol; IDA:SGD.::GO:0005634; C:nucleus; IDA:SGD.
GO:0051537; F:2 iron, 2 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
GO:0030036; P:actin cytoskeleton organization; IMP:SGD.::GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0006879; P:cellular iron ion homeostasis; IPI:SGD.::GO:0034599; P:cellular response to oxidative stress; IMP:SGD.
3O74790    244   GLRX4_SCHPO Monothiol glutaredoxin-4 OS=Schiz...2356e-59     193     42     64GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.
GO:0051537; F:2 iron, 2 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0008794; F:arsenate reductase (glutaredoxin) activity; TAS:PomBase.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0015035; F:protein disulfide oxidoreductase activity; NAS:PomBase.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0019430; P:removal of superoxide radicals; IC:PomBase.
4Q28ID3    326   GLRX3_XENTR Glutaredoxin-3 OS=Xenopus tropica...1311e-27     112     47     57GO:0005938; C:cell cortex; IEA:UniProtKB-SubCell.
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.
5Q9ZPH2    488   GRS17_ARATH Monothiol glutaredoxin-S17 OS=Ara...1247e-29     117     48     60GO:0005829; C:cytosol; IDA:TAIR.
GO:0051537; F:2 iron, 2 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
GO:0009926; P:auxin polar transport; IMP:TAIR.::GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0072593; P:reactive oxygen species metabolic process; IMP:TAIR.::GO:0051726; P:regulation of cell cycle; IEP:TAIR.::GO:0009408; P:response to heat; IMP:TAIR.
6O76003    335   GLRX3_HUMAN Glutaredoxin-3 OS=Homo sapiens (H...871e-25     106     55     70GO:0005938; C:cell cortex; IEA:UniProtKB-SubCell.::GO:0030018; C:Z disc; IEA:UniProtKB-SubCell.
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0051536; F:iron-sulfur cluster binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0010614; P:negative regulation of cardiac muscle hypertrophy; ISS:UniProtKB.::GO:0002026; P:regulation of the force of heart contraction; ISS:UniProtKB.
7Q5XJ54    326   GLRX3_DANRE Glutaredoxin 3 OS=Danio rerio (Ze...865e-27     110     56     72GO:0005938; C:cell cortex; IEA:UniProtKB-SubCell.
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.
8Q9JLZ1    337   GLRX3_RAT Glutaredoxin-3 OS=Rattus norvegicus...872e-25     106     55     70GO:0005938; C:cell cortex; IEA:UniProtKB-SubCell.::GO:0030018; C:Z disc; IEA:UniProtKB-SubCell.
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0051536; F:iron-sulfur cluster binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.::GO:0005080; F:protein kinase C binding; IDA:RGD.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.
9Q58DA7    334   GLRX3_BOVIN Glutaredoxin-3 OS=Bos taurus (Bov...1312e-26     108     45     56GO:0005938; C:cell cortex; IEA:UniProtKB-SubCell.::GO:0030018; C:Z disc; IEA:UniProtKB-SubCell.
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0051536; F:iron-sulfur cluster binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0010614; P:negative regulation of cardiac muscle hypertrophy; ISS:UniProtKB.::GO:0002026; P:regulation of the force of heart contraction; ISS:UniProtKB.
10Q9CQM9    337   GLRX3_MOUSE Glutaredoxin-3 OS=Mus musculus (M...872e-25     106     55     70GO:0005938; C:cell cortex; IEA:UniProtKB-SubCell.::GO:0030018; C:Z disc; IDA:UniProtKB.
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0051536; F:iron-sulfur cluster binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0010614; P:negative regulation of cardiac muscle hypertrophy; IMP:UniProtKB.::GO:0002026; P:regulation of the force of heart contraction; IMP:UniProtKB.
11Q86H62    240   GLRX3_DICDI Glutaredoxin-3 homolog OS=Dictyos...2163e-45     157     38     61GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.
12Q0IWL9    491   GRS11_ORYSJ Monothiol glutaredoxin-S11 OS=Ory...1152e-26     110     49     64GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0051537; F:2 iron, 2 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.
13P73056    107   YC64L_SYNY3 Uncharacterized monothiol glutare...872e-23     96.3     51     68
GO:0051537; F:2 iron, 2 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.
14Q68W05    111   GLRX2_RICTY Probable monothiol glutaredoxin-2...782e-23     96.3     54     71
GO:0051537; F:2 iron, 2 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.
15Q02784    150   GLRX5_YEAST Monothiol glutaredoxin-5, mitocho...883e-23     96.7     47     69GO:0005759; C:mitochondrial matrix; IDA:SGD.
GO:0051537; F:2 iron, 2 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0034599; P:cellular response to oxidative stress; IMP:SGD.::GO:0016226; P:iron-sulfur cluster assembly; TAS:SGD.::GO:0006970; P:response to osmotic stress; IMP:SGD.
16Q1XDA3    107   YCF64_PORYE Uncharacterized monothiol glutare...921e-22     94     46     65GO:0009507; C:chloroplast; IEA:UniProtKB-SubCell.
GO:0051537; F:2 iron, 2 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.
17Q851Y7    168   GRXS7_ORYSJ Monothiol glutaredoxin-S7, chloro...841e-22     95.5     54     70GO:0009507; C:chloroplast; IEA:UniProtKB-SubCell.
GO:0051537; F:2 iron, 2 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.
18Q6PBM1    155   GLRX5_DANRE Glutaredoxin-related protein 5, m...813e-22     94     48     74GO:0005739; C:mitochondrion; IDA:ZFIN.
GO:0051537; F:2 iron, 2 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0030097; P:hemopoiesis; IMP:ZFIN.::GO:0016226; P:iron-sulfur cluster assembly; IMP:ZFIN.
19Q86SX6    157   GLRX5_HUMAN Glutaredoxin-related protein 5, m...826e-22     93.6     48     73GO:0005739; C:mitochondrion; ISS:UniProtKB.::GO:0005634; C:nucleus; IDA:HPA.
GO:0051537; F:2 iron, 2 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0030097; P:hemopoiesis; ISS:UniProtKB.
20Q80Y14    152   GLRX5_MOUSE Glutaredoxin-related protein 5, m...827e-22     93.2     48     73GO:0005739; C:mitochondrion; IDA:UniProtKB.
GO:0051537; F:2 iron, 2 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0030097; P:hemopoiesis; ISS:UniProtKB.
21O30824    107   GLRX4_HAEDU Glutaredoxin-4 OS=Haemophilus duc...788e-22     91.7     49     71GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0051537; F:2 iron, 2 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.
22Q48833    89   GLRXA_LEGPH Probable monothiol glutaredoxin g...769e-22     91.3     50     68
GO:0051537; F:2 iron, 2 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.
23P0AC72    115   GLRX4_SHIFL Glutaredoxin-4 OS=Shigella flexne...741e-21     91.7     50     70GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0051537; F:2 iron, 2 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.
24P0AC69    115   GLRX4_ECOLI Glutaredoxin-4 OS=Escherichia col...741e-21     91.7     50     70GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0051537; F:2 iron, 2 sulfur cluster binding; IDA:EcoCyc.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.
25P0AC70    115   GLRX4_ECOL6 Glutaredoxin-4 OS=Escherichia col...741e-21     91.7     50     70GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0051537; F:2 iron, 2 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.
26P0AC71    115   GLRX4_ECO57 Glutaredoxin-4 OS=Escherichia col...741e-21     91.7     50     70GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0051537; F:2 iron, 2 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.
27O05957    107   GLRX2_RICPR Probable monothiol glutaredoxin-2...781e-21     91.3     53     67
GO:0051537; F:2 iron, 2 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.
28Q89AR8    108   GLRX4_BUCBP Glutaredoxin-4 OS=Buchnera aphidi...782e-21     90.9     45     69GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0051537; F:2 iron, 2 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.
29Q6YFE4    143   GLRX5_LACKL Monothiol glutaredoxin-5, mitocho...792e-21     91.7     46     73GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell.
GO:0051537; F:2 iron, 2 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.
30Q84Y95    173   GRS14_ARATH Monothiol glutaredoxin-S14, chlor...853e-21     92     52     68GO:0009941; C:chloroplast envelope; IDA:TAIR.::GO:0009570; C:chloroplast stroma; IDA:TAIR.
GO:0051537; F:2 iron, 2 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0015297; F:antiporter activity; IDA:TAIR.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0015038; F:glutathione disulfide oxidoreductase activity; IGI:TAIR.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
GO:0006812; P:cation transport; IDA:TAIR.::GO:0045454; P:cell redox homeostasis; IEA:InterPro.
31Q92GH5    107   GLRX2_RICCN Probable monothiol glutaredoxin-2...783e-21     90.1     53     67
GO:0051537; F:2 iron, 2 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.
records
Previous ‹‹ ›› Next Total records: 337 1 - 30
Elimate unknown annotation:
Filter for keyword on hit description:
Select upper E value:
Select lower bit score:
Select lower %idenity value:
Select lower %positive value:
Taxonomic division:
Lower limit on hit length:
Lower limit on alignment length::