UniProt_SwissProt BLAST: Single locus

Species:

Saccharomyces cerevisiae S288C

Locus:

YER174C

Length:

244

Number of sequences:

5887

Description:

YER174C GRX4 SGDID:S000000976, Chr V from 539168-538434, Genome Release 64-1-1, reverse complement, Verified ORF, "Hydroperoxide and superoxide-radical responsive glutathione-dependent oxidoreductase; monothiol glutaredoxin subfamily member along with Grx3p and Grx5p; protects cells from oxidative damage; mutant has increased aneuploidy tolerance"

rec.	Subject	Hit Length	Description	Align.Len	E value	Bit score	% ident.	% pos.	GO associations
31	Q92GH5	107	GLRX2_RICCN Probable monothiol glutaredoxin-2...	78	3e-21	90.1	53	67
									GO:0051537; F:2 iron, 2 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
									GO:0045454; P:cell redox homeostasis; IEA:InterPro.
32	Q9CMN5	109	GLRX4_PASMU Glutaredoxin-4 OS=Pasteurella mul...	87	4e-21	89.7	41	67	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0051537; F:2 iron, 2 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
									GO:0045454; P:cell redox homeostasis; IEA:InterPro.
33	Q9HDW8	146	GLRX5_SCHPO Monothiol glutaredoxin-5 OS=Schiz...	79	2e-20	89	47	71	GO:0005759; C:mitochondrial matrix; ISS:PomBase.
									GO:0051537; F:2 iron, 2 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0008794; F:arsenate reductase (glutaredoxin) activity; TAS:PomBase.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0015035; F:protein disulfide oxidoreductase activity; ISS:PomBase.
									GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0071473; P:cellular response to cation stress; IEP:PomBase.::GO:0016226; P:iron-sulfur cluster assembly; ISS:PomBase.::GO:0019430; P:removal of superoxide radicals; IC:PomBase.::GO:0051409; P:response to nitrosative stress; TAS:PomBase.
34	Q4QLD2	107	GLRX4_HAEI8 Glutaredoxin-4 OS=Haemophilus inf...	83	3e-20	87.4	42	65	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0051537; F:2 iron, 2 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
									GO:0045454; P:cell redox homeostasis; IEA:InterPro.
35	P51384	107	YCF64_PORPU Uncharacterized monothiol glutare...	77	4e-20	87	51	66	GO:0009507; C:chloroplast; IEA:UniProtKB-SubCell.
									GO:0051537; F:2 iron, 2 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
									GO:0045454; P:cell redox homeostasis; IEA:InterPro.
36	Q8LBK6	169	GRS15_ARATH Monothiol glutaredoxin-S15, mitoc...	76	9e-20	87.8	47	70	GO:0005739; C:mitochondrion; IDA:TAIR.
									GO:0051537; F:2 iron, 2 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0046872; F:metal ion binding; IDA:TAIR.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
									GO:0045454; P:cell redox homeostasis; IEA:InterPro.
37	P45085	107	GLRX4_HAEIN Glutaredoxin-4 OS=Haemophilus inf...	83	2e-19	85.5	41	64	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0051537; F:2 iron, 2 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
									GO:0045454; P:cell redox homeostasis; IEA:InterPro.
38	Q2QX01	285	GRS12_ORYSJ Monothiol glutaredoxin-S12, chlor...	87	2e-19	88.6	45	70
									GO:0051537; F:2 iron, 2 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
									GO:0045454; P:cell redox homeostasis; IEA:InterPro.
39	Q555C8	143	GLRX5_DICDI Monothiol glutaredoxin-5, mitocho...	76	2e-19	86.3	45	70	GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.
									GO:0051537; F:2 iron, 2 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
									GO:0045454; P:cell redox homeostasis; IEA:InterPro.
40	Q8H7F6	293	GRS16_ARATH Monothiol glutaredoxin-S16, chlor...	86	4e-19	87.8	44	69	GO:0009570; C:chloroplast stroma; IDA:TAIR.
									GO:0051537; F:2 iron, 2 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
									GO:0006812; P:cation transport; IDA:TAIR.::GO:0045454; P:cell redox homeostasis; IEA:InterPro.
41	P57284	108	GLRX4_BUCAI Glutaredoxin-4 OS=(Acyrthosiphon ...	86	8e-19	83.6	42	65	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0051537; F:2 iron, 2 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
									GO:0045454; P:cell redox homeostasis; IEA:InterPro.
42	Q0JM76	185	GRXS4_ORYSJ Monothiol glutaredoxin-S4, mitoch...	125	8e-19	85.5	34	55	GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.
									GO:0051537; F:2 iron, 2 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
									GO:0045454; P:cell redox homeostasis; IEA:InterPro.
43	Q8K9V6	107	GLRX4_BUCAP Glutaredoxin-4 OS=Buchnera aphidi...	76	9e-19	83.2	45	67	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0051537; F:2 iron, 2 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
									GO:0045454; P:cell redox homeostasis; IEA:InterPro.
44	Q4UK94	104	GLRX2_RICFE Probable monothiol glutaredoxin-2...	78	5e-18	81.3	47	63
									GO:0051537; F:2 iron, 2 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
									GO:0045454; P:cell redox homeostasis; IEA:InterPro.
45	Q0JQ97	185	GRXS1_ORYSJ Monothiol glutaredoxin-S1, mitoch...	76	8e-17	79.7	43	66	GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.
									GO:0051537; F:2 iron, 2 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
									GO:0045454; P:cell redox homeostasis; IEA:InterPro.
46	Q6ES52	317	TDX_ORYSJ TPR repeat-containing thioredoxin T...	96	0.000000000006	67.4	33	61
									GO:0005488; F:binding; IEA:InterPro.
									GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW.
47	Q9DGI3	107	THIO_ICTPU Thioredoxin OS=Ictalurus punctatus...	95	0.00000000001	63.5	33	57	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
									GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0043388; P:positive regulation of DNA binding; ISS:UniProtKB.::GO:0033158; P:regulation of protein import into nucleus, translocation; ISS:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0009314; P:response to radiation; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW.
48	Q9XIF4	129	TRXH7_ARATH Thioredoxin H7 OS=Arabidopsis tha...	105	0.00000000001	63.5	31	52	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
									GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0006810; P:transport; IEA:UniProtKB-KW.
49	Q6Z4I3	138	TRH21_ORYSJ Thioredoxin H2-1 OS=Oryza sativa ...	104	0.00000000002	63.5	34	53	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
									GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0006810; P:transport; IEA:UniProtKB-KW.
50	Q38879	133	TRXH2_ARATH Thioredoxin H2 OS=Arabidopsis tha...	88	0.00000000005	62	33	57	GO:0005829; C:cytosol; IDA:UniProtKB.::GO:0005739; C:mitochondrion; IDA:UniProtKB.::GO:0005886; C:plasma membrane; IDA:TAIR.
									GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0016671; F:oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor; IDA:TAIR.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
									GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0000103; P:sulfate assimilation; IGI:TAIR.::GO:0006810; P:transport; IEA:UniProtKB-KW.
51	O64394	127	TRXH_WHEAT Thioredoxin H-type OS=Triticum aes...	100	0.00000000007	61.6	32	56	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
									GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0006810; P:transport; IEA:UniProtKB-KW.
52	Q9V429	114	THIO2_DROME Thioredoxin-2 OS=Drosophila melan...	84	0.00000000007	61.2	38	61	GO:0005634; C:nucleus; IDA:FlyBase.
									GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
									GO:0045454; P:cell redox homeostasis; IDA:UniProtKB.::GO:0008340; P:determination of adult lifespan; IMP:FlyBase.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0006974; P:response to DNA damage stimulus; IMP:FlyBase.::GO:0006979; P:response to oxidative stress; IMP:FlyBase.::GO:0006810; P:transport; IEA:UniProtKB-KW.
53	Q42403	118	TRXH3_ARATH Thioredoxin H3 OS=Arabidopsis tha...	98	0.0000000001	60.5	32	57	GO:0005618; C:cell wall; IDA:TAIR.::GO:0009570; C:chloroplast stroma; IDA:TAIR.::GO:0005829; C:cytosol; IDA:UniProtKB.::GO:0005794; C:Golgi apparatus; IDA:TAIR.::GO:0005739; C:mitochondrion; IDA:TAIR.::GO:0005886; C:plasma membrane; IDA:TAIR.::GO:0009506; C:plasmodesma; IDA:TAIR.::GO:0005773; C:vacuole; IDA:TAIR.
									GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0016671; F:oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor; IDA:UniProtKB.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
									GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0050832; P:defense response to fungus; IMP:TAIR.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0010286; P:heat acclimation; IMP:UniProtKB.::GO:0006457; P:protein folding; IDA:UniProtKB.::GO:0051259; P:protein oligomerization; IDA:UniProtKB.::GO:0042542; P:response to hydrogen peroxide; IGI:TAIR.::GO:0010188; P:response to microbial phytotoxin; IMP:TAIR.::GO:0006810; P:transport; IEA:UniProtKB-KW.
54	Q9UW02	106	THIO_COPCM Thioredoxin OS=Coprinus comatus (S...	93	0.0000000001	60.1	32	56
									GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
									GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0006810; P:transport; IEA:UniProtKB-KW.
55	Q6XHI1	106	THIO2_DROYA Thioredoxin-2 OS=Drosophila yakub...	84	0.0000000003	59.7	37	60
									GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
									GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0006810; P:transport; IEA:UniProtKB-KW.
56	P60226	107	THIO1_DROYA Thioredoxin-1 OS=Drosophila yakub...	92	0.0000000005	58.9	33	55	GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
									GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0006810; P:transport; IEA:UniProtKB-KW.
57	Q39239	119	TRXH4_ARATH Thioredoxin H4 OS=Arabidopsis tha...	100	0.0000000009	58.5	30	55	GO:0005829; C:cytosol; TAS:TAIR.
									GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0016671; F:oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor; IDA:TAIR.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
									GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0006810; P:transport; IEA:UniProtKB-KW.
58	Q39362	119	TRXH2_BRANA Thioredoxin H-type 2 OS=Brassica ...	84	0.0000000009	58.5	33	56	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
									GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0006810; P:transport; IEA:UniProtKB-KW.
59	P25372	127	TRX3_YEAST Thioredoxin-3, mitochondrial OS=Sa...	110	0.000000001	58.5	32	50	GO:0005739; C:mitochondrion; IDA:SGD.
									GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
									GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0034599; P:cellular response to oxidative stress; IMP:SGD.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0006810; P:transport; IEA:UniProtKB-KW.
60	Q9BDJ3	105	THIO_CALJA Thioredoxin OS=Callithrix jacchus ...	95	0.000000001	57.8	35	54	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
									GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0043388; P:positive regulation of DNA binding; ISS:UniProtKB.::GO:0033158; P:regulation of protein import into nucleus, translocation; ISS:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0009314; P:response to radiation; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW.
61	Q9R6P9	100	THIO_MYCGA Thioredoxin OS=Mycoplasma gallisep...	101	0.000000001	57.4	32	54
									GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
									GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0006810; P:transport; IEA:UniProtKB-KW.

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