Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YER174C
Length:
244
Number of sequences:
5887
Description:
YER174C GRX4 SGDID:S000000976, Chr V from 539168-538434, Genome Release 64-1-1, reverse complement, Verified ORF, "Hydroperoxide and superoxide-radical responsive glutathione-dependent oxidoreductase; monothiol glutaredoxin subfamily member along with Grx3p and Grx5p; protects cells from oxidative damage; mutant has increased aneuploidy tolerance"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
301O80763    578   NRX1_ARATH Probable nucleoredoxin 1 OS=Arabid...1064.5     32.3     26     41GO:0005829; C:cytosol; IDA:TAIR.
GO:0047134; F:protein-disulfide reductase activity; IEA:EC.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0009860; P:pollen tube growth; IMP:TAIR.::GO:0010183; P:pollen tube guidance; IMP:TAIR.::GO:0080092; P:regulation of pollen tube growth; IMP:UniProtKB.::GO:0046686; P:response to cadmium ion; IEP:TAIR.
302Q5UQ14    106   GLRX_MIMIV Probable glutaredoxin OS=Acanthamo...761.3     32     25     50GO:0019012; C:virion; IEA:UniProtKB-SubCell.
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW.
303Q6DKJ4    435   NXN_HUMAN Nucleoredoxin OS=Homo sapiens (Huma...1791.4     33.9     21     42GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0047134; F:protein-disulfide reductase activity; IEA:EC.
GO:0072358; P:cardiovascular system development; ISS:UniProtKB.::GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0031397; P:negative regulation of protein ubiquitination; ISS:UniProtKB.::GO:0030178; P:negative regulation of Wnt receptor signaling pathway; ISS:UniProtKB.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
304P96132    91   THIO_THIRO Thioredoxin OS=Thiocapsa roseopers...591.5     31.6     20     51
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0006810; P:transport; IEA:UniProtKB-KW.
305Q7Y0F2    581   NRX12_ORYSJ Probable nucleoredoxin 1-2 OS=Ory...451.5     33.5     38     62
GO:0047134; F:protein-disulfide reductase activity; IEA:EC.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.
306Q8CXF3    192   RESA_OCEIH Thiol-disulfide oxidoreductase res...1021.5     33.1     22     44GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0016209; F:antioxidant activity; IEA:InterPro.::GO:0015036; F:disulfide oxidoreductase activity; IEA:InterPro.
GO:0017004; P:cytochrome complex assembly; IEA:UniProtKB-KW.
307Q8BUH1    149   TXN4B_MOUSE Thioredoxin-like protein 4B OS=Mu...891.6     32.7     27     45GO:0005681; C:spliceosomal complex; IEA:InterPro.
GO:0007067; P:mitosis; IEA:InterPro.::GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
308Q715T0    586   TXND3_MOUSE Thioredoxin domain-containing pro...2251.7     33.5     21     39GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:InterPro.::GO:0004550; F:nucleoside diphosphate kinase activity; IEA:InterPro.
GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0006241; P:CTP biosynthetic process; IEA:InterPro.::GO:0006183; P:GTP biosynthetic process; IEA:InterPro.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0007283; P:spermatogenesis; IEA:UniProtKB-KW.::GO:0006228; P:UTP biosynthetic process; IEA:InterPro.
309Q2KIL5    521   PDIA5_BOVIN Protein disulfide-isomerase A5 OS...831.9     33.5     24     46GO:0005788; C:endoplasmic reticulum lumen; IEA:UniProtKB-SubCell.
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0003756; F:protein disulfide isomerase activity; IEA:EC.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.
310Q8L8Z8    102   GRXS2_ARATH Monothiol glutaredoxin-S2 OS=Arab...791.9     31.6     25     44GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0051537; F:2 iron, 2 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.
311O48773    440   PDI23_ARATH Protein disulfide-isomerase 2-3 O...992     33.1     25     41GO:0005788; C:endoplasmic reticulum lumen; IEA:UniProtKB-SubCell.::GO:0005794; C:Golgi apparatus; IDA:TAIR.::GO:0005886; C:plasma membrane; IDA:TAIR.::GO:0005773; C:vacuole; IDA:TAIR.
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0003756; F:protein disulfide isomerase activity; ISS:TAIR.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0034976; P:response to endoplasmic reticulum stress; IEP:TAIR.
312Q04004    230   PLP1_YEAST Phosducin-like protein 1 OS=Saccha...642     32.7     23     55GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0031683; F:G-protein beta/gamma-subunit complex binding; IDA:SGD.
GO:0009968; P:negative regulation of signal transduction; IEA:UniProtKB-KW.::GO:0007329; P:positive regulation of transcription from RNA polymerase II promoter by pheromones; IPI:SGD.::GO:0006457; P:protein folding; IGI:SGD.
313P52589    515   PDI_WHEAT Protein disulfide-isomerase OS=Trit...822.1     33.1     28     46GO:0005788; C:endoplasmic reticulum lumen; IEA:UniProtKB-SubCell.
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0003756; F:protein disulfide isomerase activity; IEA:EC.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.
314Q54NX2    126   THIOD_DICDI Thioredoxin domain-containing pro...732.2     32     25     53GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.
315Q8N427    588   TXND3_HUMAN Thioredoxin domain-containing pro...742.4     33.1     20     46GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0015630; C:microtubule cytoskeleton; IDA:HPA.
GO:0005524; F:ATP binding; IEA:InterPro.::GO:0004550; F:nucleoside diphosphate kinase activity; IEA:InterPro.
GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0006241; P:CTP biosynthetic process; IEA:InterPro.::GO:0006183; P:GTP biosynthetic process; IEA:InterPro.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0007283; P:spermatogenesis; IEA:UniProtKB-KW.::GO:0006228; P:UTP biosynthetic process; IEA:InterPro.
316Q58E26    287   TMX2_XENLA Thioredoxin-related transmembrane ...512.4     32.7     25     51GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.
317Q7Y0E8    569   NRX11_ORYSJ Probable nucleoredoxin 1-1 OS=Ory...1123.7     32.3     21     41
GO:0047134; F:protein-disulfide reductase activity; IEA:EC.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.
318Q9XF61    507   PDI_DATGL Protein disulfide-isomerase OS=Dati...648.1     31.2     25     48GO:0005788; C:endoplasmic reticulum lumen; IEA:UniProtKB-SubCell.
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0003756; F:protein disulfide isomerase activity; IEA:EC.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.
319P80284    513   PDI_HORVU Protein disulfide-isomerase OS=Hord...652.8     32.7     28     52GO:0005788; C:endoplasmic reticulum lumen; IEA:UniProtKB-SubCell.
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0003756; F:protein disulfide isomerase activity; IEA:EC.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.
320Q9NX01    149   TXN4B_HUMAN Thioredoxin-like protein 4B OS=Ho...893.3     31.6     26     47GO:0005681; C:spliceosomal complex; IEA:InterPro.
GO:0007067; P:mitosis; IEA:InterPro.::GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
321A6QLU8    435   NXN_BOVIN Nucleoredoxin OS=Bos taurus (Bovine...343.4     32.3     29     62GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0047134; F:protein-disulfide reductase activity; IEA:EC.
GO:0072358; P:cardiovascular system development; ISS:UniProtKB.::GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0031397; P:negative regulation of protein ubiquitination; ISS:UniProtKB.::GO:0030178; P:negative regulation of Wnt receptor signaling pathway; ISS:UniProtKB.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
322Q71A37    184   PHLP3_DICDI Phosducin-like protein 3 OS=Dicty...863.6     32     26     47
GO:0045454; P:cell redox homeostasis; IEA:InterPro.
323Q5I0H9    517   PDIA5_RAT Protein disulfide-isomerase A5 OS=R...663.9     32.3     24     48GO:0005788; C:endoplasmic reticulum lumen; IEA:UniProtKB-SubCell.
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0003756; F:protein disulfide isomerase activity; IEA:EC.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0006950; P:response to stress; ISS:UniProtKB.
324P97346    435   NXN_MOUSE Nucleoredoxin OS=Mus musculus (Mous...1794.1     32.3     21     41GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IDA:MGI.
GO:0005515; F:protein binding; IPI:BHF-UCL.::GO:0047134; F:protein-disulfide reductase activity; IEA:EC.::GO:0004791; F:thioredoxin-disulfide reductase activity; IDA:MGI.
GO:0072358; P:cardiovascular system development; IMP:UniProtKB.::GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0031397; P:negative regulation of protein ubiquitination; IMP:UniProtKB.::GO:0030178; P:negative regulation of Wnt receptor signaling pathway; IMP:UniProtKB.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
325Q6GM16    414   NXN_XENLA Nucleoredoxin OS=Xenopus laevis (Af...324.8     32     31     63GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0047134; F:protein-disulfide reductase activity; IEA:EC.
GO:0072358; P:cardiovascular system development; ISS:UniProtKB.::GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0031397; P:negative regulation of protein ubiquitination; ISS:UniProtKB.::GO:0030178; P:negative regulation of Wnt receptor signaling pathway; ISS:UniProtKB.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
326Q5RCH2    525   PDIA2_PONAB Protein disulfide-isomerase A2 OS...895     32     29     46GO:0005788; C:endoplasmic reticulum lumen; IEA:UniProtKB-SubCell.
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0003756; F:protein disulfide isomerase activity; IEA:EC.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.::GO:0005496; F:steroid binding; IEA:UniProtKB-KW.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.
327Q9M7X9    183   CITRX_ARATH Thioredoxin-like protein CITRX, c...605.1     31.2     25     50GO:0009507; C:chloroplast; IDA:TAIR.::GO:0009295; C:nucleoid; IDA:TAIR.::GO:0009579; C:thylakoid; IDA:TAIR.
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0015035; F:protein disulfide oxidoreductase activity; IDA:TAIR.::GO:0047134; F:protein-disulfide reductase activity; IDA:TAIR.
GO:0045454; P:cell redox homeostasis; IMP:TAIR.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0009657; P:plastid organization; IMP:TAIR.::GO:0006810; P:transport; IEA:UniProtKB-KW.
328Q921X9    517   PDIA5_MOUSE Protein disulfide-isomerase A5 OS...665.2     32     24     47GO:0005788; C:endoplasmic reticulum lumen; IEA:UniProtKB-SubCell.
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0003756; F:protein disulfide isomerase activity; IEA:EC.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0006950; P:response to stress; IDA:UniProtKB.
329Q13087    525   PDIA2_HUMAN Protein disulfide-isomerase A2 OS...895.5     32     28     47GO:0005788; C:endoplasmic reticulum lumen; IEA:UniProtKB-SubCell.
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0003756; F:protein disulfide isomerase activity; TAS:ProtInc.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.::GO:0005496; F:steroid binding; IEA:UniProtKB-KW.
GO:0006915; P:apoptotic process; IMP:HGNC.::GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0006457; P:protein folding; TAS:ProtInc.::GO:0006621; P:protein retention in ER lumen; TAS:ProtInc.::GO:0001666; P:response to hypoxia; IMP:HGNC.
330Q69ST6    545   PID13_ORYSJ Protein disulfide isomerase-like ...685.6     32     28     49GO:0005788; C:endoplasmic reticulum lumen; IEA:UniProtKB-SubCell.
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0003756; F:protein disulfide isomerase activity; IEA:EC.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.
331P29828    512   PDI_MEDSA Protein disulfide-isomerase OS=Medi...1185.6     32     19     44GO:0005788; C:endoplasmic reticulum lumen; IEA:UniProtKB-SubCell.
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0003756; F:protein disulfide isomerase activity; IEA:EC.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.
records
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