Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YER174C
Length:
244
Number of sequences:
5887
Description:
YER174C GRX4 SGDID:S000000976, Chr V from 539168-538434, Genome Release 64-1-1, reverse complement, Verified ORF, "Hydroperoxide and superoxide-radical responsive glutathione-dependent oxidoreductase; monothiol glutaredoxin subfamily member along with Grx3p and Grx5p; protects cells from oxidative damage; mutant has increased aneuploidy tolerance"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
271Q10M18    279   TRL12_ORYSJ Thioredoxin-like 1-2, chloroplast...710.16     36.2     23     51
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0006810; P:transport; IEA:UniProtKB-KW.
272P04785    509   PDIA1_RAT Protein disulfide-isomerase OS=Ratt...1090.17     36.6     23     45GO:0005788; C:endoplasmic reticulum lumen; IEA:UniProtKB-SubCell.::GO:0042470; C:melanosome; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0003756; F:protein disulfide isomerase activity; IMP:RGD.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.::GO:0046982; F:protein heterodimerization activity; IPI:RGD.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.
273Q9D1Q6    406   ERP44_MOUSE Endoplasmic reticulum resident pr...680.17     36.6     25     49GO:0005788; C:endoplasmic reticulum lumen; ISS:UniProtKB.::GO:0005789; C:endoplasmic reticulum membrane; ISS:UniProtKB.
GO:0005515; F:protein binding; IPI:IntAct.::GO:0003756; F:protein disulfide isomerase activity; ISS:UniProtKB.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0009100; P:glycoprotein metabolic process; ISS:UniProtKB.::GO:0006457; P:protein folding; ISS:UniProtKB.::GO:0006986; P:response to unfolded protein; ISS:UniProtKB.
274Q8R4U2    509   PDIA1_CRIGR Protein disulfide-isomerase OS=Cr...1160.17     36.6     22     46GO:0005788; C:endoplasmic reticulum lumen; IEA:UniProtKB-SubCell.::GO:0042470; C:melanosome; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0003756; F:protein disulfide isomerase activity; IEA:EC.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.
275P77395    284   YBBN_ECOLI Uncharacterized protein ybbN OS=Es...810.18     36.2     22     49
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0003756; F:protein disulfide isomerase activity; IDA:EcoliWiki.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.::GO:0051082; F:unfolded protein binding; IDA:EcoliWiki.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.
276Q6NRT6    796   DJC10_XENLA DnaJ homolog subfamily C member 1...1020.19     36.6     24     44GO:0005788; C:endoplasmic reticulum lumen; IEA:UniProtKB-SubCell.::GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0031072; F:heat shock protein binding; IEA:InterPro.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.::GO:0051082; F:unfolded protein binding; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0006457; P:protein folding; IEA:InterPro.
277Q9BS26    406   ERP44_HUMAN Endoplasmic reticulum resident pr...680.2     36.2     25     49GO:0005788; C:endoplasmic reticulum lumen; IDA:UniProtKB.::GO:0005789; C:endoplasmic reticulum membrane; IDA:UniProtKB.::GO:0005793; C:endoplasmic reticulum-Golgi intermediate compartment; IDA:UniProtKB.
GO:0003756; F:protein disulfide isomerase activity; IDA:UniProtKB.
GO:0045454; P:cell redox homeostasis; TAS:UniProtKB.::GO:0009100; P:glycoprotein metabolic process; IDA:UniProtKB.::GO:0006457; P:protein folding; IDA:UniProtKB.::GO:0006986; P:response to unfolded protein; IDA:UniProtKB.
278Q6FMI2    142   DIB1_CANGA Spliceosomal protein DIB1 OS=NRRL ...530.29     34.7     34     58GO:0005681; C:spliceosomal complex; IEA:InterPro.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
279Q3T0L2    406   ERP44_BOVIN Endoplasmic reticulum resident pr...680.3     35.8     25     47GO:0005788; C:endoplasmic reticulum lumen; IEA:UniProtKB-SubCell.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.
280Q8L8T2    125   GRXC1_ARATH Glutaredoxin-C1 OS=Arabidopsis th...970.34     34.3     24     53GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW.
281O34342    80   YOSR_BACSU SPBc2 prophage-derived thioredoxin...510.34     33.5     27     53
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.
282Q7M1B9    110   THIO_CHLAA Thioredoxin OS=Chloroflexus aurant...810.34     33.9     19     48
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0006810; P:transport; IEA:UniProtKB-KW.
283Q1ZXE0    104   THIO4_DICDI Putative thioredoxin-4 OS=Dictyos...820.34     33.9     23     45
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0006467; P:protein thiol-disulfide exchange; ISS:dictyBase.::GO:0006810; P:transport; IEA:UniProtKB-KW.
284Q8KEA4    101   THIO1_CHLTE Thioredoxin-1 OS=Chlorobium tepid...720.35     33.5     18     49
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0006810; P:transport; IEA:UniProtKB-KW.
285D3Z6P0    527   PDIA2_MOUSE Protein disulfide-isomerase A2 OS...1181     34.3     29     44GO:0005788; C:endoplasmic reticulum lumen; IEA:UniProtKB-SubCell.
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0003756; F:protein disulfide isomerase activity; TAS:MGI.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.::GO:0005496; F:steroid binding; IEA:UniProtKB-KW.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.
286F4IXE4    730   TTL2_ARATH TPR repeat-containing thioredoxin ...700.39     35.4     31     56
GO:0005488; F:binding; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.
287Q43116    498   PDI_RICCO Protein disulfide-isomerase OS=Rici...642.7     32.7     27     50GO:0005788; C:endoplasmic reticulum lumen; IDA:UniProtKB.
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0003756; F:protein disulfide isomerase activity; IEA:EC.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.
288Q9H3N1    280   TMX1_HUMAN Thioredoxin-related transmembrane ...740.49     34.7     24     42GO:0005789; C:endoplasmic reticulum membrane; IDA:UniProtKB.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005624; C:membrane fraction; IDA:UniProtKB.
GO:0030612; F:arsenate reductase (thioredoxin) activity; NAS:UniProtKB.::GO:0015036; F:disulfide oxidoreductase activity; IDA:UniProtKB.
GO:0006916; P:anti-apoptosis; IDA:UniProtKB.::GO:0008283; P:cell proliferation; NAS:UniProtKB.::GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0006260; P:DNA replication; NAS:UniProtKB.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006888; P:ER to Golgi vesicle-mediated transport; TAS:UniProtKB.::GO:0045321; P:leukocyte activation; NAS:UniProtKB.::GO:0045927; P:positive regulation of growth; NAS:UniProtKB.::GO:0045893; P:positive regulation of transcription, DNA-dependent; NAS:UniProtKB.::GO:0006950; P:response to stress; NAS:UniProtKB.::GO:0007165; P:signal transduction; NAS:UniProtKB.
289P54399    496   PDI_DROME Protein disulfide-isomerase OS=Dros...890.51     35     21     51GO:0060187; C:cell pole; IDA:FlyBase.::GO:0005788; C:endoplasmic reticulum lumen; IEA:UniProtKB-SubCell.::GO:0005615; C:extracellular space; IDA:FlyBase.::GO:0045169; C:fusome; IDA:FlyBase.::GO:0005811; C:lipid particle; IDA:FlyBase.::GO:0043025; C:neuronal cell body; IDA:FlyBase.::GO:0005635; C:nuclear envelope; IDA:FlyBase.::GO:0048471; C:perinuclear region of cytoplasm; IDA:FlyBase.::GO:0005791; C:rough endoplasmic reticulum; IDA:FlyBase.::GO:0070732; C:spindle envelope; IDA:FlyBase.
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0003756; F:protein disulfide isomerase activity; IEA:EC.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.
290Q6Z4N3    279   TRL11_ORYSJ Thioredoxin-like 1-1, chloroplast...680.55     34.7     24     51
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0006810; P:transport; IEA:UniProtKB-KW.
291Q6GI31    1257   ATL_STAAR Bifunctional autolysin OS=Staphyloc...570.58     35     35     54GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
GO:0004040; F:amidase activity; IEA:InterPro.::GO:0033925; F:mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase activity; IEA:EC.::GO:0008745; F:N-acetylmuramoyl-L-alanine amidase activity; IEA:EC.
GO:0010382; P:cellular cell wall macromolecule metabolic process; IEA:InterPro.::GO:0007047; P:cellular cell wall organization; IEA:UniProtKB-KW.::GO:0009253; P:peptidoglycan catabolic process; IEA:InterPro.
292O77404    144   TYPX_TRYBB Tryparedoxin OS=Trypanosoma brucei...470.69     33.5     34     49
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW.
293Q503L9    418   NXN_DANRE Nucleoredoxin OS=Danio rerio (Zebra...700.79     34.3     29     49GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0047134; F:protein-disulfide reductase activity; IEA:EC.
GO:0072358; P:cardiovascular system development; ISS:UniProtKB.::GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0031397; P:negative regulation of protein ubiquitination; ISS:UniProtKB.::GO:0030178; P:negative regulation of Wnt receptor signaling pathway; ISS:UniProtKB.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
294Q0Z7W6    278   TMX1_BOVIN Thioredoxin-related transmembrane ...740.8     34.3     24     42GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW.
295Q9MAU6    447   PDI22_ARATH Protein disulfide-isomerase like ...1390.8     34.3     23     43GO:0005788; C:endoplasmic reticulum lumen; IEA:UniProtKB-SubCell.::GO:0009505; C:plant-type cell wall; IDA:TAIR.
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0003756; F:protein disulfide isomerase activity; ISS:TAIR.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0034976; P:response to endoplasmic reticulum stress; IEP:TAIR.
296P12865    497   BS2_TRYBB Bloodstream-specific protein 2 OS=T...640.82     34.3     25     48
GO:0016853; F:isomerase activity; IEA:UniProtKB-KW.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.
297Q8VBT0    278   TMX1_MOUSE Thioredoxin-related transmembrane ...740.88     33.9     23     43GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW.
298Q8H2V6    189   CITRX_ORYSJ Thioredoxin-like protein CITRX, c...590.94     33.5     24     54GO:0009507; C:chloroplast; IEA:UniProtKB-SubCell.
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0006810; P:transport; IEA:UniProtKB-KW.
299P80028    113   TRXH_CHLRE Thioredoxin H-type OS=Chlamydomona...960.94     32.7     28     49GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0006810; P:transport; IEA:UniProtKB-KW.
300Q6DFS0    287   TMX2_XENTR Thioredoxin-related transmembrane ...541.2     33.9     24     52GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.
301O80763    578   NRX1_ARATH Probable nucleoredoxin 1 OS=Arabid...1064.5     32.3     26     41GO:0005829; C:cytosol; IDA:TAIR.
GO:0047134; F:protein-disulfide reductase activity; IEA:EC.
GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0009860; P:pollen tube growth; IMP:TAIR.::GO:0010183; P:pollen tube guidance; IMP:TAIR.::GO:0080092; P:regulation of pollen tube growth; IMP:UniProtKB.::GO:0046686; P:response to cadmium ion; IEP:TAIR.
records
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