UniProt_SwissProt BLAST: Single locus

Species:

Saccharomyces cerevisiae S288C

Locus:

YER174C

Length:

244

Number of sequences:

5887

Description:

YER174C GRX4 SGDID:S000000976, Chr V from 539168-538434, Genome Release 64-1-1, reverse complement, Verified ORF, "Hydroperoxide and superoxide-radical responsive glutathione-dependent oxidoreductase; monothiol glutaredoxin subfamily member along with Grx3p and Grx5p; protects cells from oxidative damage; mutant has increased aneuploidy tolerance"

rec.	Subject	Hit Length	Description	Align.Len	E value	Bit score	% ident.	% pos.	GO associations
121	Q8IFW4	157	THIOT_DROME Thioredoxin-T OS=Drosophila melan...	104	0.0000008	50.8	26	55	GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0000806; C:Y chromosome; IDA:UniProtKB.
									GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
									GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0006457; P:protein folding; IDA:FlyBase.::GO:0006974; P:response to DNA damage stimulus; IMP:FlyBase.::GO:0006810; P:transport; IEA:UniProtKB-KW.
122	O65049	125	TRXH_PICMA Thioredoxin H-type OS=Picea marian...	75	0.0000008	50.4	29	59	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
									GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0006810; P:transport; IEA:UniProtKB-KW.
123	P68176	123	TRXH_BRAOL Thioredoxin H-type OS=Brassica ole...	78	0.0000008	50.4	31	56	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
									GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0006810; P:transport; IEA:UniProtKB-KW.
124	P68177	123	TRXH1_BRANA Thioredoxin H-type 1 OS=Brassica ...	78	0.0000008	50.4	31	56	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
									GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0006810; P:transport; IEA:UniProtKB-KW.
125	Q5JMR9	168	TRXY_ORYSJ Thioredoxin Y, chloroplastic OS=Or...	76	0.000001	50.8	30	58
									GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
									GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0006810; P:transport; IEA:UniProtKB-KW.
126	Q9Z7P5	102	THIO_CHLPN Thioredoxin OS=Chlamydia pneumonia...	103	0.000001	49.7	23	55
									GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
									GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0006810; P:transport; IEA:UniProtKB-KW.
127	Q05739	107	THIO_STRCL Thioredoxin OS=Streptomyces clavul...	77	0.000001	49.7	29	56
									GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
									GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0006810; P:transport; IEA:UniProtKB-KW.
128	Q655X0	174	TRXO_ORYSJ Thioredoxin O, mitochondrial OS=Or...	109	0.000001	50.4	29	51	GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.
									GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
									GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0006810; P:transport; IEA:UniProtKB-KW.
129	Q8LDI5	118	CXXS1_ARATH Thioredoxin-like protein CXXS1 OS...	105	0.000001	49.7	29	52	GO:0005829; C:cytosol; IDA:TAIR.
									GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0003756; F:protein disulfide isomerase activity; IDA:TAIR.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
									GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0006467; P:protein thiol-disulfide exchange; IDA:TAIR.
130	Q96419	116	TRXH_FAGES Thioredoxin H-type OS=Fagopyrum es...	93	0.000002	49.3	26	55	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
									GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0006810; P:transport; IEA:UniProtKB-KW.
131	P97615	166	THIOM_RAT Thioredoxin, mitochondrial OS=Rattu...	66	0.000002	50.1	35	59	GO:0030425; C:dendrite; IDA:RGD.::GO:0005739; C:mitochondrion; IDA:RGD.::GO:0043025; C:neuronal cell body; IDA:RGD.
									GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0005515; F:protein binding; IPI:RGD.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
									GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0031669; P:cellular response to nutrient levels; IEP:RGD.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0048678; P:response to axon injury; IEP:RGD.::GO:0042493; P:response to drug; IEP:RGD.::GO:0009749; P:response to glucose stimulus; IEP:RGD.::GO:0009725; P:response to hormone stimulus; IEP:RGD.::GO:0001666; P:response to hypoxia; IEP:RGD.::GO:0007584; P:response to nutrient; IEP:RGD.::GO:0014070; P:response to organic cyclic compound; IEP:RGD.::GO:0006979; P:response to oxidative stress; IEP:RGD.::GO:0006810; P:transport; IEA:UniProtKB-KW.
132	P97493	166	THIOM_MOUSE Thioredoxin, mitochondrial OS=Mus...	66	0.000002	50.1	35	59	GO:0005739; C:mitochondrion; IDA:MGI.
									GO:0009055; F:electron carrier activity; IEA:InterPro.
									GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0006810; P:transport; IEA:UniProtKB-KW.
133	Q6P902	515	TXND2_MOUSE Thioredoxin domain-containing pro...	91	0.000002	52	32	55	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0009434; C:microtubule-based flagellum; IDA:MGI.
									GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
									GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0006467; P:protein thiol-disulfide exchange; IDA:MGI.::GO:0007283; P:spermatogenesis; IEA:UniProtKB-KW.
134	Q8L7S9	167	TRXY2_ARATH Thioredoxin Y2, chloroplastic OS=...	78	0.000002	50.1	27	59	GO:0009570; C:chloroplast stroma; IDA:TAIR.
									GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0008047; F:enzyme activator activity; IDA:UniProtKB.::GO:0016671; F:oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor; IDA:UniProtKB.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
									GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0009416; P:response to light stimulus; IEP:UniProtKB.::GO:0006810; P:transport; IEA:UniProtKB-KW.
135	Q6NPF9	172	TRXY1_ARATH Thioredoxin Y1, chloroplastic OS=...	86	0.000002	50.1	31	59	GO:0009570; C:chloroplast stroma; IDA:TAIR.
									GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0008047; F:enzyme activator activity; IDA:UniProtKB.::GO:0016671; F:oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor; IDA:UniProtKB.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
									GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0006810; P:transport; IEA:UniProtKB-KW.
136	Q86VQ3	553	TXND2_HUMAN Thioredoxin domain-containing pro...	77	0.000002	51.6	36	51	GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0005730; C:nucleolus; IDA:HPA.
									GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0045735; F:nutrient reservoir activity; IEA:InterPro.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.::GO:0004791; F:thioredoxin-disulfide reductase activity; IDA:UniProtKB.
									GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0045454; P:cell redox homeostasis; NAS:UniProtKB.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0007283; P:spermatogenesis; NAS:UniProtKB.
137	P10472	108	THIO_CHLLT Thioredoxin OS=Chlorobium limicola...	82	0.000002	48.9	24	55
									GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
									GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0006810; P:transport; IEA:UniProtKB-KW.
138	Q95108	166	THIOM_BOVIN Thioredoxin, mitochondrial OS=Bos...	66	0.000003	49.7	35	59	GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.
									GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
									GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0006810; P:transport; IEA:UniProtKB-KW.
139	O22022	102	THIO_CYAME Thioredoxin OS=Cyanidioschyzon mer...	80	0.000003	48.5	24	56	GO:0009507; C:chloroplast; IEA:UniProtKB-SubCell.
									GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
									GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0006810; P:transport; IEA:UniProtKB-KW.
140	Q9XFH9	185	TRXF2_ARATH Thioredoxin F2, chloroplastic OS=...	89	0.000003	50.1	31	56	GO:0009570; C:chloroplast stroma; IDA:TAIR.::GO:0005829; C:cytosol; IDA:TAIR.
									GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0008047; F:enzyme activator activity; IDA:TAIR.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
									GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0006810; P:transport; IEA:UniProtKB-KW.
141	Q9LXZ8	154	TRH10_ARATH Putative thioredoxin H10 OS=Arabi...	90	0.000003	49.3	28	53	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
									GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0006810; P:transport; IEA:UniProtKB-KW.
142	Q19297	146	YZ73_CAEEL Uncharacterized monothiol glutared...	108	0.000003	48.9	33	56
									GO:0051537; F:2 iron, 2 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
									GO:0045454; P:cell redox homeostasis; IEA:InterPro.
143	Q1RKN1	105	THIO_RICBR Thioredoxin OS=Rickettsia bellii (...	63	0.000003	48.1	29	63
									GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
									GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0006810; P:transport; IEA:UniProtKB-KW.
144	P51225	107	THIO_PORPU Thioredoxin OS=Porphyra purpurea. ...	84	0.000004	48.1	30	58	GO:0009507; C:chloroplast; IEA:UniProtKB-SubCell.
									GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
									GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0006810; P:transport; IEA:UniProtKB-KW.
145	Q99757	166	THIOM_HUMAN Thioredoxin, mitochondrial OS=Hom...	66	0.000005	48.9	33	59	GO:0005739; C:mitochondrion; IDA:HPA.::GO:0005730; C:nucleolus; IDA:HPA.
									GO:0009055; F:electron carrier activity; IEA:InterPro.
									GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0006810; P:transport; IEA:UniProtKB-KW.
146	P52230	110	THIO_STRCO Thioredoxin OS=Streptomyces coelic...	100	0.000005	47.8	27	51
									GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
									GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0006810; P:transport; IEA:UniProtKB-KW.
147	P00275	105	THIO1_CORNE Thioredoxin C-1 OS=Corynebacteriu...	75	0.000006	47.8	25	59
									GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
									GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0006810; P:transport; IEA:UniProtKB-KW.
148	P33791	106	THIO_STRAU Thioredoxin OS=Streptomyces aureof...	79	0.000006	47.8	22	58
									GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
									GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0006810; P:transport; IEA:UniProtKB-KW.
149	P08058	106	THIO_RHOSH Thioredoxin OS=Rhodobacter sphaero...	75	0.000006	47.4	28	53
									GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
									GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0006810; P:transport; IEA:UniProtKB-KW.
150	P14949	104	THIO_BACSU Thioredoxin OS=Bacillus subtilis (...	100	0.000007	47.4	25	55
									GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
									GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0006810; P:transport; IEA:UniProtKB-KW.
151	Q4UNK3	105	THIO_RICFE Thioredoxin OS=Rickettsia felis (s...	63	0.000007	47.4	27	65
									GO:0009055; F:electron carrier activity; IEA:InterPro.::GO:0015035; F:protein disulfide oxidoreductase activity; IEA:InterPro.
									GO:0045454; P:cell redox homeostasis; IEA:InterPro.::GO:0022900; P:electron transport chain; IEA:UniProtKB-KW.::GO:0006662; P:glycerol ether metabolic process; IEA:InterPro.::GO:0006810; P:transport; IEA:UniProtKB-KW.

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