Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YER172C
Length:
2163
Number of sequences:
5887
Description:
YER172C BRR2 SGDID:S000000974, Chr V from 536021-529530, Genome Release 64-1-1, reverse complement, Verified ORF, "RNA-dependent ATPase RNA helicase (DEIH box); required for disruption of U4/U6 base-pairing in native snRNPs to activate the spliceosome for catalysis; homologous to human U5-200kD"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
1P32639    2163   BRR2_YEAST Pre-mRNA-splicing helicase BRR2 OS...21630     4470     100     100GO:0005681; C:spliceosomal complex; IEA:UniProtKB-KW.::GO:0046540; C:U4/U6 x U5 tri-snRNP complex; IDA:SGD.::GO:0005682; C:U5 snRNP; IDA:SGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004004; F:ATP-dependent RNA helicase activity; IMP:SGD.::GO:0003676; F:nucleic acid binding; IEA:InterPro.
GO:0000388; P:spliceosome conformational change to release U4 (or U4atac) and U1 (or U11); IMP:SGD.
2Q9UT24    2176   BRR2_SCHPO Pre-mRNA-splicing factor brr2 OS=S...22050     1667     42     62GO:0005829; C:cytosol; IDA:PomBase.::GO:0005681; C:spliceosomal complex; IDA:PomBase.::GO:0046540; C:U4/U6 x U5 tri-snRNP complex; ISS:PomBase.::GO:0005682; C:U5 snRNP; ISS:PomBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004004; F:ATP-dependent RNA helicase activity; ISS:PomBase.::GO:0003676; F:nucleic acid binding; IEA:InterPro.
GO:0000393; P:spliceosomal conformational changes to generate catalytic conformation; IGI:PomBase.
3Q9VUV9    2142   U520_DROME Putative U5 small nuclear ribonucl...21930     1525     40     59GO:0071013; C:catalytic step 2 spliceosome; IDA:FlyBase.::GO:0071011; C:precatalytic spliceosome; IDA:FlyBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004004; F:ATP-dependent RNA helicase activity; ISS:FlyBase.::GO:0003676; F:nucleic acid binding; IEA:InterPro.
GO:0007067; P:mitosis; IMP:FlyBase.::GO:0000398; P:nuclear mRNA splicing, via spliceosome; IC:FlyBase.::GO:0000381; P:regulation of alternative nuclear mRNA splicing, via spliceosome; IMP:FlyBase.
4O75643    2136   U520_HUMAN U5 small nuclear ribonucleoprotein...21910     1519     39     59GO:0071013; C:catalytic step 2 spliceosome; IDA:UniProtKB.::GO:0005654; C:nucleoplasm; TAS:Reactome.::GO:0005682; C:U5 snRNP; IDA:HGNC.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IDA:HGNC.::GO:0003676; F:nucleic acid binding; IEA:InterPro.
GO:0000354; P:cis assembly of pre-catalytic spliceosome; IC:HGNC.
5Q9U2G0    2145   U520_CAEEL Putative U5 small nuclear ribonucl...20880     1402     38     59GO:0005681; C:spliceosomal complex; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003676; F:nucleic acid binding; IEA:InterPro.
GO:0016477; P:cell migration; IMP:WormBase.::GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0007281; P:germ cell development; IMP:WormBase.::GO:0008406; P:gonad development; IMP:WormBase.::GO:0040007; P:growth; IMP:WormBase.::GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0002119; P:nematode larval development; IMP:WormBase.::GO:0018991; P:oviposition; IMP:WormBase.::GO:0042127; P:regulation of cell proliferation; IMP:WormBase.::GO:0040020; P:regulation of meiosis; IMP:WormBase.::GO:0008380; P:RNA splicing; ISS:UniProtKB.
6Q55CI8    2237   HELCL_DICDI Activating signal cointegrator 1 ...21490     1387     38     58GO:0005681; C:spliceosomal complex; ISS:dictyBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004004; F:ATP-dependent RNA helicase activity; ISS:dictyBase.::GO:0003676; F:nucleic acid binding; IEA:InterPro.
GO:0008380; P:RNA splicing; ISS:dictyBase.
7F1NTD6    2211   ASCC3_CHICK Activating signal cointegrator 1 ...19510     1084     35     55GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0043140; F:ATP-dependent 3'-5' DNA helicase activity; ISS:UniProtKB.::GO:0003676; F:nucleic acid binding; IEA:InterPro.
GO:0008283; P:cell proliferation; ISS:UniProtKB.::GO:0006307; P:DNA dealkylation involved in DNA repair; ISS:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
8E9PZJ8    2198   ASCC3_MOUSE Activating signal cointegrator 1 ...19550     1081     35     54GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0043140; F:ATP-dependent 3'-5' DNA helicase activity; ISS:UniProtKB.::GO:0003676; F:nucleic acid binding; IEA:InterPro.
GO:0008283; P:cell proliferation; ISS:UniProtKB.::GO:0006307; P:DNA dealkylation involved in DNA repair; ISS:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
9Q54G57    2195   HELC1_DICDI Activating signal cointegrator 1 ...17840     1077     36     57
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003676; F:nucleic acid binding; IEA:InterPro.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
10Q8N3C0    2202   ASCC3_HUMAN Activating signal cointegrator 1 ...19510     1076     35     54GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; TAS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0043140; F:ATP-dependent 3'-5' DNA helicase activity; IDA:UniProtKB.::GO:0003676; F:nucleic acid binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0008283; P:cell proliferation; IMP:UniProtKB.::GO:0006307; P:DNA dealkylation involved in DNA repair; IDA:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
11F1LPQ2    2197   ASCC3_RAT Activating signal cointegrator 1 co...19520     1074     35     54GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0043140; F:ATP-dependent 3'-5' DNA helicase activity; ISS:UniProtKB.::GO:0003676; F:nucleic acid binding; IEA:InterPro.
GO:0008283; P:cell proliferation; ISS:UniProtKB.::GO:0006307; P:DNA dealkylation involved in DNA repair; ISS:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
12E1BNG3    2201   ASCC3_BOVIN Activating signal cointegrator 1 ...19560     1068     35     54GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0043140; F:ATP-dependent 3'-5' DNA helicase activity; ISS:UniProtKB.::GO:0003676; F:nucleic acid binding; IEA:InterPro.
GO:0008283; P:cell proliferation; ISS:UniProtKB.::GO:0006307; P:DNA dealkylation involved in DNA repair; ISS:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
13E7F8F4    1534   ASCC3_DANRE Activating signal cointegrator 1 ...15840     936     36     54GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0043140; F:ATP-dependent 3'-5' DNA helicase activity; ISS:UniProtKB.::GO:0003676; F:nucleic acid binding; IEA:InterPro.
GO:0008283; P:cell proliferation; ISS:UniProtKB.::GO:0006307; P:DNA dealkylation involved in DNA repair; ISS:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
14O60072    1935   MUG81_SCHPO Putative helicase mug81 OS=Schizo...17510     941     34     55GO:0005829; C:cytosol; IDA:PomBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004004; F:ATP-dependent RNA helicase activity; ISS:PomBase.::GO:0003676; F:nucleic acid binding; IEA:InterPro.
GO:0007126; P:meiosis; IEA:UniProtKB-KW.::GO:2000765; P:regulation of cytoplasmic translation; ISS:PomBase.
15P53327    1967   SLH1_YEAST Antiviral helicase SLH1 OS=Sacchar...7167e-98     356     31     53GO:0005737; C:cytoplasm; IDA:SGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003676; F:nucleic acid binding; IEA:InterPro.
GO:0006417; P:regulation of translation; IMP:SGD.::GO:0009615; P:response to virus; IEA:UniProtKB-KW.
16A2PYH4    1435   HFM1_HUMAN Probable ATP-dependent DNA helicas...6233e-37     158     26     43
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003676; F:nucleic acid binding; IEA:InterPro.
17A2RUV5    1336   HFM1_XENTR Probable ATP-dependent DNA helicas...6852e-37     158     25     44
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003676; F:nucleic acid binding; IEA:InterPro.
18P51979    1187   HFM1_YEAST ATP-dependent DNA helicase MER3 OS...6422e-35     152     26     45GO:0005634; C:nucleus; IDA:SGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003678; F:DNA helicase activity; IDA:SGD.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0006268; P:DNA unwinding involved in replication; IDA:SGD.::GO:0007131; P:reciprocal meiotic recombination; IMP:SGD.::GO:0007129; P:synapsis; IMP:SGD.
19Q9YFQ8    735   HELS_AERPE Putative ski2-type helicase OS=100...2000.00007     52     25     49
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003677; F:DNA binding; IEA:InterPro.
GO:0006281; P:DNA repair; IEA:InterPro.
20Q9V0A9    715   HELS_PYRAB Putative ski2-type helicase OS=Pyr...4950.0000002     60.1     22     42
GO:0005524; F:ATP binding; IEA:HAMAP.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003677; F:DNA binding; IEA:HAMAP.
GO:0006281; P:DNA repair; IEA:InterPro.
21Q97AI2    674   HELS_THEVO Putative ski2-type helicase OS=154...4730.005     45.8     21     42
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003676; F:nucleic acid binding; IEA:InterPro.
22O59025    715   HELS_PYRHO Putative ski2-type helicase OS=NBR...4910.000000006     65.1     23     44
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003677; F:DNA binding; IEA:InterPro.
GO:0006281; P:DNA repair; IEA:InterPro.
23O73946    720   HELS_PYRFU Putative ski2-type helicase OS=Pyr...1860.00008     51.6     24     46
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003677; F:DNA binding; IEA:InterPro.
GO:0006281; P:DNA repair; IEA:InterPro.
24A8MB76    756   HELS_CALMQ Putative ski2-type helicase OS=/ I...5966e-43     173     29     47
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003677; F:DNA binding; IEA:InterPro.
GO:0006281; P:DNA repair; IEA:InterPro.
25Q8TL39    730   HELS_METAC Putative ski2-type helicase OS=C2A...4680.009     45.1     22     41
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003677; F:DNA binding; IEA:InterPro.
GO:0006281; P:DNA repair; IEA:InterPro.
26A3MSA1    708   HELS_PYRCJ Putative ski2-type helicase OS=Pyr...5278e-42     169     30     47
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003677; F:DNA binding; IEA:InterPro.
GO:0006281; P:DNA repair; IEA:InterPro.
27Q3IU46    747   HELS_NATPD Putative ski2-type helicase OS=Nat...6072e-41     168     27     46
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003677; F:DNA binding; IEA:InterPro.
GO:0006281; P:DNA repair; IEA:InterPro.
28Q97VY9    708   HELS_SULSO Putative ski2-type helicase OS=P2)...1870.005     45.8     22     42
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003677; F:DNA binding; IEA:InterPro.
GO:0006281; P:DNA repair; IEA:InterPro.
29Q465R3    729   HELS_METBF Putative ski2-type helicase OS=Met...4720.00003     52.8     21     40
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003677; F:DNA binding; IEA:InterPro.
GO:0006281; P:DNA repair; IEA:InterPro.
30Q8PZR7    730   HELS_METMA Putative ski2-type helicase OS=JCM...4710.071     42     21     40
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003676; F:nucleic acid binding; IEA:InterPro.
31A6UN73    751   HELS_METVS Putative ski2-type helicase OS=Met...3430.001     48.1     21     41
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003677; F:DNA binding; IEA:InterPro.
GO:0006281; P:DNA repair; IEA:InterPro.
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