UniProt_SwissProt BLAST: Single locus

Species:

Saccharomyces cerevisiae S288C

Locus:

YER172C

Length:

2163

Number of sequences:

5887

Description:

YER172C BRR2 SGDID:S000000974, Chr V from 536021-529530, Genome Release 64-1-1, reverse complement, Verified ORF, "RNA-dependent ATPase RNA helicase (DEIH box); required for disruption of U4/U6 base-pairing in native snRNPs to activate the spliceosome for catalysis; homologous to human U5-200kD"

rec.	Subject	Hit Length	Description	Align.Len	E value	Bit score	% ident.	% pos.	GO associations
91	Q6CT85	487	RRP3_KLULA ATP-dependent rRNA helicase RRP3 O...	140	1.4	37.4	27	44	GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
									GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
92	A7LFZ6	1657	DCL4_ORYSJ Endoribonuclease Dicer homolog 4 O...	195	0.0001	51.2	25	47	GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003725; F:double-stranded RNA binding; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004525; F:ribonuclease III activity; IEA:InterPro.
									GO:0010492; P:maintenance of shoot apical meristem identity; IMP:UniProtKB.::GO:0009944; P:polarity specification of adaxial/abaxial axis; IMP:UniProtKB.::GO:0010267; P:production of ta-siRNAs involved in RNA interference; IDA:UniProtKB.::GO:0048608; P:reproductive structure development; IMP:UniProtKB.
93	Q0CIQ3	445	RRP3_ASPTN ATP-dependent rRNA helicase rrp3 O...	180	0.0001	50.4	28	48	GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
									GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
94	Q7RY59	515	RRP3_NEUCR ATP-dependent rRNA helicase rrp-3 ...	409	0.0001	50.4	23	41	GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
									GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
95	Q10HL3	1410	DCL2A_ORYSJ Endoribonuclease Dicer homolog 2a...	175	0.0002	50.8	28	47	GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003725; F:double-stranded RNA binding; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004525; F:ribonuclease III activity; IEA:InterPro.
									GO:0031047; P:gene silencing by RNA; IEA:UniProtKB-KW.::GO:0006396; P:RNA processing; IEA:InterPro.
96	Q69LX2	1377	DCL2B_ORYSJ Endoribonuclease Dicer homolog 2b...	177	0.0002	50.8	28	47	GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003725; F:double-stranded RNA binding; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004525; F:ribonuclease III activity; IEA:InterPro.
									GO:0031047; P:gene silencing by RNA; IEA:UniProtKB-KW.::GO:0006396; P:RNA processing; IEA:InterPro.
97	Q6P9R1	639	DDX51_MOUSE ATP-dependent RNA helicase DDX51 ...	241	0.0002	50.4	25	42	GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
									GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
98	Q9BYX4	1025	IFIH1_HUMAN Interferon-induced helicase C dom...	197	0.0002	50.4	30	49	GO:0005829; C:cytosol; TAS:Reactome.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:InterPro.::GO:0003725; F:double-stranded RNA binding; IDA:UniProtKB.::GO:0004386; F:helicase activity; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0043021; F:ribonucleoprotein complex binding; IPI:UniProtKB.::GO:0003727; F:single-stranded RNA binding; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IDA:UniProtKB.
									GO:0039528; P:cytoplasmic pattern recognition receptor signaling pathway in response to virus; TAS:UniProtKB.::GO:0009597; P:detection of virus; TAS:BHF-UCL.::GO:0045087; P:innate immune response; TAS:UniProtKB.::GO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW.::GO:0032480; P:negative regulation of type I interferon production; TAS:Reactome.::GO:0032727; P:positive regulation of interferon-alpha production; IMP:UniProtKB.::GO:0032728; P:positive regulation of interferon-beta production; IMP:UniProtKB.::GO:0016925; P:protein sumoylation; IDA:UniProtKB.::GO:0042981; P:regulation of apoptotic process; IEA:InterPro.::GO:0034344; P:regulation of type III interferon production; TAS:UniProtKB.
99	P52126	729	YFJK_ECOLI Uncharacterized protein yfjK OS=Es...	436	0.0002	50.1	23	36
									GO:0005524; F:ATP binding; IEA:InterPro.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003676; F:nucleic acid binding; IEA:InterPro.
100	Q9NQI0	724	DDX4_HUMAN Probable ATP-dependent RNA helicas...	185	0.0003	50.1	25	46	GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.::GO:0071546; C:pi-body; ISS:UniProtKB.::GO:0071547; C:piP-body; ISS:UniProtKB.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003676; F:nucleic acid binding; IEA:InterPro.
									GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0030317; P:sperm motility; IMP:UniProtKB.
101	Q8IYD8	2048	FANCM_HUMAN Fanconi anemia group M protein OS...	160	0.0003	50.1	31	47	GO:0071821; C:FANCM-MHF complex; IDA:UniProtKB.::GO:0043240; C:Fanconi anaemia nuclear complex; IDA:UniProtKB.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003682; F:chromatin binding; IDA:UniProtKB.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0004518; F:nuclease activity; IEA:InterPro.::GO:0005515; F:protein binding; IPI:UniProtKB.
									GO:0006281; P:DNA repair; TAS:Reactome.::GO:0031297; P:replication fork processing; IMP:UniProtKB.::GO:0000712; P:resolution of meiotic recombination intermediates; IMP:UniProtKB.
102	A2RB17	467	RRP3_ASPNC ATP-dependent rRNA helicase rrp3 O...	192	0.0003	49.3	26	45	GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
									GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
103	Q6GWX0	722	DDX4_PIG Probable ATP-dependent RNA helicase ...	185	0.0004	49.3	25	46	GO:0033391; C:chromatoid body; IDA:MGI.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.::GO:0071546; C:pi-body; ISS:UniProtKB.::GO:0071547; C:piP-body; ISS:UniProtKB.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003676; F:nucleic acid binding; IEA:InterPro.
									GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
104	Q5B5E7	465	RRP3_EMENI ATP-dependent rRNA helicase rrp3 O...	189	0.0004	48.9	28	47	GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
									GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
105	Q4WRP2	655	MS116_ASPFU ATP-dependent RNA helicase mss116...	200	0.0004	49.3	26	42	GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
									GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0006417; P:regulation of translation; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
106	P0C5H7	1429	DCL2_EMENI Dicer-like protein 2 OS=194 / M139...	183	0.0005	49.3	29	46
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004525; F:ribonuclease III activity; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
									GO:0050688; P:regulation of defense response to virus; IEA:UniProtKB-KW.::GO:0009615; P:response to virus; IEA:UniProtKB-KW.::GO:0006396; P:RNA processing; IEA:InterPro.
107	Q5W5U4	729	DDX4_BOVIN Probable ATP-dependent RNA helicas...	185	0.0007	48.5	25	46	GO:0033391; C:chromatoid body; IDA:MGI.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.::GO:0071546; C:pi-body; ISS:UniProtKB.::GO:0071547; C:piP-body; ISS:UniProtKB.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003676; F:nucleic acid binding; IEA:InterPro.
									GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
108	Q99J87	678	DHX58_MOUSE Probable ATP-dependent RNA helica...	181	0.0007	48.5	29	45	GO:0005737; C:cytoplasm; IDA:MGI.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:InterPro.::GO:0003725; F:double-stranded RNA binding; ISS:UniProtKB.::GO:0004386; F:helicase activity; IEA:UniProtKB-KW.::GO:0003727; F:single-stranded RNA binding; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; ISS:UniProtKB.
									GO:0051607; P:defense response to virus; IMP:UniProtKB.::GO:0045087; P:innate immune response; IEA:UniProtKB-KW.::GO:0045824; P:negative regulation of innate immune response; IMP:UniProtKB.::GO:0039534; P:negative regulation of MDA-5 signaling pathway; ISS:UniProtKB.::GO:0039536; P:negative regulation of RIG-I signaling pathway; IMP:UniProtKB.::GO:0032480; P:negative regulation of type I interferon production; IMP:UniProtKB.::GO:1900245; P:positive regulation of MDA-5 signaling pathway; IMP:UniProtKB.::GO:1900246; P:positive regulation of RIG-I signaling pathway; IMP:UniProtKB.::GO:0032481; P:positive regulation of type I interferon production; IMP:UniProtKB.
109	O94762	991	RECQ5_HUMAN ATP-dependent DNA helicase Q5 OS=...	404	0.001	48.1	23	39	GO:0005737; C:cytoplasm; NAS:UniProtKB.::GO:0016591; C:DNA-directed RNA polymerase II, holoenzyme; IDA:UniProtKB.::GO:0031965; C:nuclear membrane; IDA:HPA.::GO:0005730; C:nucleolus; IDA:HPA.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003678; F:DNA helicase activity; NAS:UniProtKB.::GO:0003676; F:nucleic acid binding; IEA:InterPro.
									GO:0006310; P:DNA recombination; IEA:InterPro.::GO:0006281; P:DNA repair; TAS:ProtInc.
110	Q4R5S7	725	DDX4_MACFA Probable ATP-dependent RNA helicas...	185	0.001	47.8	25	46	GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.::GO:0071546; C:pi-body; ISS:UniProtKB.::GO:0071547; C:piP-body; ISS:UniProtKB.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003676; F:nucleic acid binding; IEA:InterPro.
									GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
111	Q6FUA6	595	DBP9_CANGA ATP-dependent RNA helicase DBP9 OS...	157	0.001	47.4	27	48	GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
									GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
112	Q1E306	730	ROK1_COCIM ATP-dependent RNA helicase ROK1 OS...	129	0.001	47.4	29	50	GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
									GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
113	Q5A1A0	1187	MPH1_CANAL ATP-dependent DNA helicase MPH1 OS...	161	0.001	47.8	30	50	GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
									GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
114	Q6CEB8	753	DRS1_YARLI ATP-dependent RNA helicase DRS1 OS...	364	0.001	47.4	24	42	GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
									GO:0042254; P:ribosome biogenesis; IEA:UniProtKB-KW.
115	Q6FNK8	493	RRP3_CANGA ATP-dependent rRNA helicase RRP3 O...	140	0.71	38.5	29	44	GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
									GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
116	A1CNK1	738	ROK1_ASPCL ATP-dependent RNA helicase rok1 OS...	166	0.002	47	22	46	GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
									GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
117	Q75EW9	487	RRP3_ASHGO ATP-dependent rRNA helicase RRP3 O...	140	2.3	37	26	44	GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
									GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
118	A6QRQ7	485	RRP3_AJECN ATP-dependent rRNA helicase RRP3 O...	180	0.003	46.2	27	49	GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
									GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
119	Q4WJE9	472	RRP3_ASPFU ATP-dependent rRNA helicase rrp3 O...	203	0.003	46.2	26	46	GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
									GO:0006364; P:rRNA processing; IEA:UniProtKB-KW.
120	Q8R5F7	1025	IFIH1_MOUSE Interferon-induced helicase C dom...	194	0.003	46.6	28	49	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:InterPro.::GO:0003725; F:double-stranded RNA binding; ISS:UniProtKB.::GO:0004386; F:helicase activity; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:MGI.::GO:0003727; F:single-stranded RNA binding; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; ISS:UniProtKB.
									GO:0045087; P:innate immune response; IMP:UniProtKB.::GO:0032727; P:positive regulation of interferon-alpha production; ISS:UniProtKB.::GO:0032728; P:positive regulation of interferon-beta production; ISS:UniProtKB.::GO:0016925; P:protein sumoylation; ISS:UniProtKB.::GO:0042981; P:regulation of apoptotic process; IEA:InterPro.::GO:0009615; P:response to virus; IMP:UniProtKB.
121	Q8BGE5	2021	FANCM_MOUSE Fanconi anemia group M protein ho...	126	0.003	46.6	30	50	GO:0071821; C:FANCM-MHF complex; ISS:UniProtKB.::GO:0043240; C:Fanconi anaemia nuclear complex; ISS:UniProtKB.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008026; F:ATP-dependent helicase activity; IEA:InterPro.::GO:0003682; F:chromatin binding; ISS:UniProtKB.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0004518; F:nuclease activity; IEA:InterPro.
									GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0031297; P:replication fork processing; ISS:UniProtKB.::GO:0000712; P:resolution of meiotic recombination intermediates; ISS:UniProtKB.

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