Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YER166W
Length:
1571
Number of sequences:
5887
Description:
YER166W DNF1 SGDID:S000000968, Chr V from 512744-517459, Genome Release 64-1-1, Verified ORF, "Aminophospholipid translocase (flippase) that localizes primarily to the plasma membrane; contributes to endocytosis, protein transport and cell polarity; type 4 P-type ATPase"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
121Q10900    1625   CTPI_MYCTU Probable cation-transporting ATPas...1740.29     39.7     25     40GO:0005618; C:cell wall; IDA:MTBBASE.::GO:0005829; C:cytosol; IDA:MTBBASE.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IDA:MTBBASE.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0015662; F:ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0006812; P:cation transport; IEA:InterPro.
122Q9YH26    1023   AT1A1_OREMO Sodium/potassium-transporting ATP...3140.003     45.8     25     40GO:0016021; C:integral to membrane; ISS:UniProtKB.::GO:0005886; C:plasma membrane; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005391; F:sodium:potassium-exchanging ATPase activity; IEA:EC.
GO:0006754; P:ATP biosynthetic process; IEA:InterPro.
123Q5RDR3    1023   AT1A1_PONAB Sodium/potassium-transporting ATP...3790.004     45.8     23     39GO:0016021; C:integral to membrane; ISS:UniProtKB.::GO:0005886; C:plasma membrane; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005391; F:sodium:potassium-exchanging ATPase activity; ISS:UniProtKB.
GO:0006754; P:ATP biosynthetic process; IEA:InterPro.::GO:0002028; P:regulation of sodium ion transport; ISS:UniProtKB.
124Q8VDN2    1023   AT1A1_MOUSE Sodium/potassium-transporting ATP...3820.004     45.8     24     39GO:0016323; C:basolateral plasma membrane; IDA:MGI.::GO:0016021; C:integral to membrane; ISS:UniProtKB.::GO:0042470; C:melanosome; IEA:UniProtKB-SubCell.::GO:0005792; C:microsome; IDA:MGI.::GO:0042383; C:sarcolemma; IDA:MGI.
GO:0003869; F:4-nitrophenylphosphatase activity; IMP:MGI.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:MGI.::GO:0005391; F:sodium:potassium-exchanging ATPase activity; IMP:MGI.
GO:0006754; P:ATP biosynthetic process; IEA:InterPro.::GO:0031947; P:negative regulation of glucocorticoid biosynthetic process; IMP:MGI.::GO:0045822; P:negative regulation of heart contraction; IMP:MGI.::GO:0045823; P:positive regulation of heart contraction; IMP:MGI.::GO:0045989; P:positive regulation of striated muscle contraction; IMP:MGI.::GO:0008217; P:regulation of blood pressure; IGI:MGI.::GO:0002028; P:regulation of sodium ion transport; ISS:UniProtKB.::GO:0002026; P:regulation of the force of heart contraction; IMP:MGI.::GO:0042493; P:response to drug; IMP:MGI.
125Q64392    1033   AT12A_CAVPO Potassium-transporting ATPase alp...2800.006     45.1     25     37GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008900; F:hydrogen:potassium-exchanging ATPase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0006754; P:ATP biosynthetic process; IEA:InterPro.
126Q64578    994   AT2A1_RAT Sarcoplasmic/endoplasmic reticulum ...4370.004     45.4     23     36GO:0005793; C:endoplasmic reticulum-Golgi intermediate compartment; ISS:UniProtKB.::GO:0031673; C:H zone; ISS:UniProtKB.::GO:0031674; C:I band; ISS:UniProtKB.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005792; C:microsome; IDA:RGD.::GO:0048471; C:perinuclear region of cytoplasm; ISS:UniProtKB.::GO:0033017; C:sarcoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; ISS:UniProtKB.::GO:0005509; F:calcium ion binding; ISS:UniProtKB.::GO:0005388; F:calcium-transporting ATPase activity; ISS:UniProtKB.::GO:0005338; F:nucleotide-sugar transmembrane transporter activity; IDA:RGD.::GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0006754; P:ATP biosynthetic process; IEA:InterPro.::GO:0045988; P:negative regulation of striated muscle contraction; ISS:UniProtKB.::GO:0031448; P:positive regulation of fast-twitch skeletal muscle fiber contraction; ISS:UniProtKB.::GO:0043434; P:response to peptide hormone stimulus; IDA:UniProtKB.
127O53114    1609   CTPI_MYCLE Probable cation-transporting ATPas...610.004     45.8     39     57GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0015662; F:ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0006812; P:cation transport; IEA:InterPro.
128Q8R429    994   AT2A1_MOUSE Sarcoplasmic/endoplasmic reticulu...4370.004     45.4     23     36GO:0005793; C:endoplasmic reticulum-Golgi intermediate compartment; ISS:UniProtKB.::GO:0031673; C:H zone; ISS:UniProtKB.::GO:0031674; C:I band; ISS:UniProtKB.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0048471; C:perinuclear region of cytoplasm; ISS:UniProtKB.::GO:0033017; C:sarcoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; ISS:UniProtKB.::GO:0005509; F:calcium ion binding; ISS:UniProtKB.::GO:0005388; F:calcium-transporting ATPase activity; ISS:UniProtKB.
GO:0006754; P:ATP biosynthetic process; IEA:InterPro.::GO:0045988; P:negative regulation of striated muscle contraction; ISS:UniProtKB.::GO:0031448; P:positive regulation of fast-twitch skeletal muscle fiber contraction; ISS:UniProtKB.
129P06687    1013   AT1A3_RAT Sodium/potassium-transporting ATPas...546     35.4     37     56GO:0030424; C:axon; IDA:RGD.::GO:0005783; C:endoplasmic reticulum; ISS:UniProtKB.::GO:0005794; C:Golgi apparatus; ISS:UniProtKB.::GO:0043209; C:myelin sheath; IDA:RGD.::GO:0005890; C:sodium:potassium-exchanging ATPase complex; IDA:RGD.
GO:0005524; F:ATP binding; TAS:RGD.::GO:0019829; F:cation-transporting ATPase activity; TAS:RGD.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:RGD.::GO:0005391; F:sodium:potassium-exchanging ATPase activity; ISS:UniProtKB.
GO:0006754; P:ATP biosynthetic process; IEA:InterPro.::GO:0015991; P:ATP hydrolysis coupled proton transport; TAS:RGD.
130Q6PIC6    1013   AT1A3_MOUSE Sodium/potassium-transporting ATP...546     35.4     37     56GO:0005783; C:endoplasmic reticulum; ISS:UniProtKB.::GO:0005794; C:Golgi apparatus; ISS:UniProtKB.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005634; C:nucleus; IDA:MGI.::GO:0005886; C:plasma membrane; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005391; F:sodium:potassium-exchanging ATPase activity; ISS:UniProtKB.
GO:0008344; P:adult locomotory behavior; IMP:MGI.::GO:0006754; P:ATP biosynthetic process; IEA:InterPro.::GO:0035235; P:ionotropic glutamate receptor signaling pathway; IMP:MGI.::GO:0007613; P:memory; IMP:MGI.::GO:0042493; P:response to drug; IMP:MGI.::GO:0008542; P:visual learning; IMP:MGI.
131P50996    1034   ATP4A_CANFA Potassium-transporting ATPase alp...3330.006     45.1     23     37GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008900; F:hydrogen:potassium-exchanging ATPase activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.
GO:0006754; P:ATP biosynthetic process; IEA:InterPro.::GO:0015991; P:ATP hydrolysis coupled proton transport; IEA:InterPro.
132Q92126    1031   ATP4A_XENLA Potassium-transporting ATPase alp...2020.14     40.8     26     41GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008900; F:hydrogen:potassium-exchanging ATPase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0006754; P:ATP biosynthetic process; IEA:InterPro.
133A2VDL6    1020   AT1A2_BOVIN Sodium/potassium-transporting ATP...2980.008     44.7     26     41GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005391; F:sodium:potassium-exchanging ATPase activity; IEA:EC.
GO:0006754; P:ATP biosynthetic process; IEA:InterPro.
134P09626    1033   ATP4A_RAT Potassium-transporting ATPase alpha...2820.041     42.4     26     38GO:0016324; C:apical plasma membrane; IDA:UniProtKB.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008900; F:hydrogen:potassium-exchanging ATPase activity; TAS:RGD.::GO:0000287; F:magnesium ion binding; IEA:InterPro.
GO:0006754; P:ATP biosynthetic process; IEA:InterPro.::GO:0015991; P:ATP hydrolysis coupled proton transport; IEA:InterPro.::GO:0001696; P:gastric acid secretion; TAS:RGD.
135P13587    1091   ATN1_YEAST Sodium transport ATPase 1 OS=Sacch...6690.009     44.7     21     36GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IDA:UniProtKB.::GO:0001950; C:plasma membrane enriched fraction; IDA:SGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:InterPro.::GO:0008556; F:potassium-transporting ATPase activity; IMP:SGD.::GO:0008554; F:sodium-exporting ATPase activity, phosphorylative mechanism; IDA:SGD.
GO:0006754; P:ATP biosynthetic process; IEA:InterPro.::GO:0042149; P:cellular response to glucose starvation; IMP:SGD.::GO:0006972; P:hyperosmotic response; IGI:SGD.::GO:0009651; P:response to salt stress; IDA:UniProtKB.
136Q9WV27    1032   AT1A4_MOUSE Sodium/potassium-transporting ATP...2050.009     44.7     26     42GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005391; F:sodium:potassium-exchanging ATPase activity; IEA:EC.
GO:0006754; P:ATP biosynthetic process; IEA:InterPro.::GO:0030641; P:regulation of cellular pH; ISS:UniProtKB.::GO:0030317; P:sperm motility; ISS:UniProtKB.
137Q04956    1956   ATX1_PLAFA Probable cation-transporting ATPas...1160.011     44.3     23     44GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0015662; F:ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0006812; P:cation transport; IEA:InterPro.
138P24798    1010   AT1A3_CHICK Sodium/potassium-transporting ATP...548.9     34.7     35     56GO:0005783; C:endoplasmic reticulum; ISS:UniProtKB.::GO:0005794; C:Golgi apparatus; ISS:UniProtKB.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005391; F:sodium:potassium-exchanging ATPase activity; ISS:UniProtKB.
GO:0006754; P:ATP biosynthetic process; IEA:InterPro.
139P35315    1011   ATC_TRYBB Probable calcium-transporting ATPas...2130.11     40.8     25     43GO:0020016; C:flagellar pocket; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005388; F:calcium-transporting ATPase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:InterPro.
GO:0006754; P:ATP biosynthetic process; IEA:InterPro.
140P27112    1035   ATP4A_RABIT Potassium-transporting ATPase alp...2820.12     40.8     26     38GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008900; F:hydrogen:potassium-exchanging ATPase activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.
GO:0006754; P:ATP biosynthetic process; IEA:InterPro.::GO:0015991; P:ATP hydrolysis coupled proton transport; IEA:InterPro.
141P19156    1034   ATP4A_PIG Potassium-transporting ATPase alpha...2824     35.8     25     37GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008900; F:hydrogen:potassium-exchanging ATPase activity; IEA:EC.::GO:0000287; F:magnesium ion binding; IEA:InterPro.
GO:0006754; P:ATP biosynthetic process; IEA:InterPro.::GO:0015991; P:ATP hydrolysis coupled proton transport; IEA:InterPro.
142P20648    1035   ATP4A_HUMAN Potassium-transporting ATPase alp...2820.53     38.5     25     37GO:0005887; C:integral to plasma membrane; TAS:ProtInc.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008900; F:hydrogen:potassium-exchanging ATPase activity; TAS:ProtInc.::GO:0000287; F:magnesium ion binding; IEA:InterPro.
GO:0006754; P:ATP biosynthetic process; IEA:InterPro.::GO:0015991; P:ATP hydrolysis coupled proton transport; IEA:InterPro.
143Q6RWA9    1014   AT1A_TAESO Sodium/potassium-transporting ATPa...3840.012     44.3     22     38GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005391; F:sodium:potassium-exchanging ATPase activity; IEA:EC.
GO:0006754; P:ATP biosynthetic process; IEA:InterPro.
144D2WKD8    1020   AT1A2_PIG Sodium/potassium-transporting ATPas...2980.014     43.9     26     40GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005391; F:sodium:potassium-exchanging ATPase activity; IEA:EC.
GO:0006754; P:ATP biosynthetic process; IEA:InterPro.
145P05023    1023   AT1A1_HUMAN Sodium/potassium-transporting ATP...3790.014     43.9     23     39GO:0042470; C:melanosome; IEA:UniProtKB-SubCell.::GO:0005890; C:sodium:potassium-exchanging ATPase complex; TAS:ProtInc.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0005391; F:sodium:potassium-exchanging ATPase activity; ISS:UniProtKB.
GO:0006754; P:ATP biosynthetic process; IEA:InterPro.::GO:0002028; P:regulation of sodium ion transport; ISS:UniProtKB.
146P22189    1037   ATC3_SCHPO Calcium-transporting ATPase 3 OS=S...3150.014     43.9     25     38GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005388; F:calcium-transporting ATPase activity; TAS:PomBase.::GO:0046872; F:metal ion binding; IEA:InterPro.
GO:0006754; P:ATP biosynthetic process; IEA:InterPro.::GO:0006874; P:cellular calcium ion homeostasis; TAS:PomBase.
147Q92036    1042   AT12A_BUFMA Potassium-transporting ATPase alp...2909.3     34.7     23     37GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008900; F:hydrogen:potassium-exchanging ATPase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0006754; P:ATP biosynthetic process; IEA:InterPro.
148P54707    1039   AT12A_HUMAN Potassium-transporting ATPase alp...471     37.7     43     60GO:0005889; C:hydrogen:potassium-exchanging ATPase complex; TAS:ProtInc.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008900; F:hydrogen:potassium-exchanging ATPase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0006754; P:ATP biosynthetic process; IEA:InterPro.
149Q64541    1028   AT1A4_RAT Sodium/potassium-transporting ATPas...2040.019     43.5     25     41GO:0005890; C:sodium:potassium-exchanging ATPase complex; TAS:RGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005391; F:sodium:potassium-exchanging ATPase activity; IDA:MGI.
GO:0006754; P:ATP biosynthetic process; IEA:InterPro.::GO:0030641; P:regulation of cellular pH; ISS:UniProtKB.::GO:0030317; P:sperm motility; ISS:UniProtKB.
150P05024    1021   AT1A1_PIG Sodium/potassium-transporting ATPas...479.9     34.7     36     57GO:0016021; C:integral to membrane; ISS:UniProtKB.::GO:0042470; C:melanosome; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005391; F:sodium:potassium-exchanging ATPase activity; ISS:UniProtKB.
GO:0006754; P:ATP biosynthetic process; IEA:InterPro.::GO:0002028; P:regulation of sodium ion transport; ISS:UniProtKB.
151P90747    1178   YE56_CAEEL Probable cation-transporting ATPas...3140.021     43.1     22     40GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0015662; F:ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0006812; P:cation transport; IEA:InterPro.
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