Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YER155C
Length:
2167
Number of sequences:
5887
Description:
YER155C BEM2 SGDID:S000000957, Chr V from 482848-476345, Genome Release 64-1-1, reverse complement, Verified ORF, "Rho GTPase activating protein (RhoGAP) involved in the control of cytoskeleton organization and cellular morphogenesis; required for bud emergence"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
31P46941    837   TG325_CAEEL WW domain-containing protein tag-...1953e-19     98.6     31     52GO:0005622; C:intracellular; IEA:InterPro.
GO:0005543; F:phospholipid binding; IEA:InterPro.
GO:0007165; P:signal transduction; IEA:InterPro.
32Q12979    859   ABR_HUMAN Active breakpoint cluster region-re...1814e-19     98.2     35     50GO:0005829; C:cytosol; TAS:Reactome.
GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro.
GO:0006915; P:apoptotic process; TAS:Reactome.::GO:0008624; P:induction of apoptosis by extracellular signals; TAS:Reactome.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.
33Q03070    295   CHIO_RAT Beta-chimaerin OS=Rattus norvegicus ...2043e-17     89     30     50GO:0005622; C:intracellular; IEA:InterPro.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0001565; F:phorbol ester receptor activity; TAS:RGD.::GO:0030675; F:Rac GTPase activator activity; IDA:RGD.
GO:0001675; P:acrosome assembly; IEP:RGD.::GO:0035556; P:intracellular signal transduction; IEA:InterPro.
34Q5VT97    1194   SYDE2_HUMAN Rho GTPase-activating protein SYD...1914e-17     92.4     31     51GO:0005829; C:cytosol; TAS:Reactome.
GO:0005100; F:Rho GTPase activator activity; ISS:UniProtKB.
GO:0032862; P:activation of Rho GTPase activity; ISS:UniProtKB.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.
35Q9VIS1    1843   CDGAP_DROME GTPase-activating protein CdGAPr ...2224e-17     92.4     31     51GO:0005622; C:intracellular; IEA:InterPro.
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
GO:0031290; P:retinal ganglion cell axon guidance; IMP:UniProtKB.::GO:0007165; P:signal transduction; IEA:InterPro.
36P52757    468   CHIO_HUMAN Beta-chimaerin OS=Homo sapiens (Hu...2044e-17     90.5     30     50GO:0005829; C:cytosol; TAS:Reactome.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005070; F:SH3/SH2 adaptor activity; TAS:ProtInc.
GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.
37Q17QN0    334   CHIN_BOVIN N-chimaerin OS=Bos taurus (Bovine)...2056e-17     88.2     30     50GO:0005622; C:intracellular; IEA:InterPro.
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0048013; P:ephrin receptor signaling pathway; ISS:UniProtKB.::GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0008045; P:motor axon guidance; ISS:UniProtKB.::GO:0050770; P:regulation of axonogenesis; ISS:UniProtKB.
38Q80XD1    332   CHIO_MOUSE Beta-chimaerin OS=Mus musculus (Mo...2057e-17     87.8     31     50GO:0005622; C:intracellular; IEA:InterPro.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0035556; P:intracellular signal transduction; IEA:InterPro.
39Q559A0    1164   GACU_DICDI Rho GTPase-activating protein gacU...1738e-17     91.3     32     55GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005622; C:intracellular; IEA:InterPro.
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
GO:0007165; P:signal transduction; IEA:InterPro.
40Q54FG5    873   GACJJ_DICDI Rho GTPase-activating protein gac...1968e-17     90.9     30     51GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.
GO:0007165; P:signal transduction; IEA:InterPro.
41Q6PCS4    1337   RHG29_DANRE Rho GTPase-activating protein 29 ...2031e-16     90.9     31     49GO:0005622; C:intracellular; IEA:InterPro.
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0035556; P:intracellular signal transduction; IEA:InterPro.
42Q91YM2    1499   RHG35_MOUSE Rho GTPase-activating protein 35 ...2022e-16     89.7     30     50GO:0015629; C:actin cytoskeleton; IDA:MGI.::GO:0005737; C:cytoplasm; IDA:MGI.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0005525; F:GTP binding; IEA:InterPro.::GO:0005096; F:GTPase activator activity; TAS:MGI.
GO:0043010; P:camera-type eye development; IMP:MGI.::GO:0030900; P:forebrain development; IMP:MGI.::GO:0007229; P:integrin-mediated signaling pathway; TAS:MGI.::GO:0043116; P:negative regulation of vascular permeability; IMP:MGI.::GO:0001843; P:neural tube closure; IMP:MGI.::GO:0008360; P:regulation of cell shape; IDA:MGI.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
43Q9BRR9    750   RHG09_HUMAN Rho GTPase-activating protein 9 O...2072e-16     89.4     26     47GO:0005829; C:cytosol; TAS:Reactome.::GO:0005622; C:intracellular; IEA:InterPro.
GO:0005096; F:GTPase activator activity; IDA:MGI.::GO:0005543; F:phospholipid binding; IEA:InterPro.
GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.::GO:0007165; P:signal transduction; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.
44P15882    459   CHIN_HUMAN N-chimaerin OS=Homo sapiens (Human...1783e-16     87.8     32     50GO:0005829; C:cytosol; TAS:Reactome.::GO:0005622; C:intracellular; IEA:InterPro.
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005070; F:SH3/SH2 adaptor activity; TAS:ProtInc.
GO:0048013; P:ephrin receptor signaling pathway; ISS:UniProtKB.::GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0008045; P:motor axon guidance; ISS:UniProtKB.::GO:0050770; P:regulation of axonogenesis; ISS:UniProtKB.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.
45P81128    1513   RHG35_RAT Rho GTPase-activating protein 35 OS...2023e-16     89.4     30     50GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0005525; F:GTP binding; IEA:InterPro.::GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
46Q9Z1N3    2626   MYO9A_RAT Unconventional myosin-IXa OS=Rattus...1965e-16     89     31     51GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0016459; C:myosin complex; IEA:UniProtKB-KW.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0003774; F:motor activity; IEA:InterPro.
GO:0035556; P:intracellular signal transduction; IEA:InterPro.
47B2RTY4    2548   MYO9A_HUMAN Unconventional myosin-IXa OS=Homo...1966e-16     88.6     31     51GO:0005829; C:cytosol; TAS:Reactome.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0016461; C:unconventional myosin complex; NAS:UniProtKB.
GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0003774; F:motor activity; IEA:InterPro.
GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.::GO:0007601; P:visual perception; TAS:ProtInc.
48P83509    1500   RHG35_CANFA Rho GTPase-activating protein 35 ...2026e-16     88.2     30     49GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0005525; F:GTP binding; IEA:InterPro.::GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
GO:0045892; P:negative regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0042478; P:regulation of eye photoreceptor cell development; NAS:UniProtKB.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
49Q8C170    2542   MYO9A_MOUSE Unconventional myosin-IXa OS=Mus ...1967e-16     88.6     31     51GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0016459; C:myosin complex; IEA:UniProtKB-KW.
GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0003774; F:motor activity; IEA:InterPro.
GO:0035556; P:intracellular signal transduction; IEA:InterPro.
50Q91V57    459   CHIN_MOUSE N-chimaerin OS=Mus musculus (Mouse...1787e-16     86.3     32     49GO:0005622; C:intracellular; IEA:InterPro.
GO:0046875; F:ephrin receptor binding; IPI:UniProtKB.::GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.
GO:0048013; P:ephrin receptor signaling pathway; IMP:UniProtKB.::GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0008045; P:motor axon guidance; IMP:UniProtKB.::GO:0050770; P:regulation of axonogenesis; IDA:UniProtKB.::GO:0032314; P:regulation of Rac GTPase activity; IDA:UniProtKB.
51Q9NRY4    1513   RHG35_HUMAN Rho GTPase-activating protein 35 ...2027e-16     88.2     30     49GO:0005829; C:cytosol; TAS:Reactome.::GO:0005634; C:nucleus; IC:UniProtKB.
GO:0003677; F:DNA binding; TAS:ProtInc.::GO:0005525; F:GTP binding; IEA:InterPro.::GO:0005100; F:Rho GTPase activator activity; TAS:Reactome.::GO:0003714; F:transcription corepressor activity; TAS:ProtInc.
GO:0007411; P:axon guidance; TAS:Reactome.::GO:0045892; P:negative regulation of transcription, DNA-dependent; IDA:UniProtKB.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.::GO:0006351; P:transcription, DNA-dependent; TAS:ProtInc.
52P30337    334   CHIN_RAT N-chimaerin OS=Rattus norvegicus (Ra...1780.000000000000001     84.3     31     49GO:0005622; C:intracellular; IEA:InterPro.
GO:0005096; F:GTPase activator activity; TAS:RGD.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0001565; F:phorbol ester receptor activity; TAS:RGD.
GO:0048013; P:ephrin receptor signaling pathway; ISS:UniProtKB.::GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0008045; P:motor axon guidance; ISS:UniProtKB.::GO:0050770; P:regulation of axonogenesis; ISS:UniProtKB.
53Q9DBZ9    737   SYDE1_MOUSE Rho GTPase-activating protein SYD...1750.000000000000002     85.9     33     53GO:0005622; C:intracellular; IEA:InterPro.
GO:0005100; F:Rho GTPase activator activity; ISS:UniProtKB.
GO:0032862; P:activation of Rho GTPase activity; ISS:UniProtKB.::GO:0007165; P:signal transduction; IEA:InterPro.
54O94988    1023   FA13A_HUMAN Protein FAM13A OS=Homo sapiens (H...2400.000000000000003     85.9     28     50GO:0005829; C:cytosol; TAS:Reactome.
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.
55O94466    695   RGA7_SCHPO Probable Rho-GTPase-activating pro...1790.000000000000004     85.1     29     51GO:0030479; C:actin cortical patch; ISS:PomBase.::GO:0032153; C:cell division site; IDA:PomBase.::GO:0005829; C:cytosol; IDA:PomBase.
GO:0005100; F:Rho GTPase activator activity; ISS:PomBase.
GO:0030036; P:actin cytoskeleton organization; ISS:PomBase.::GO:0007165; P:signal transduction; IEA:InterPro.
56Q8CGF1    1266   RHG29_MOUSE Rho GTPase-activating protein 29 ...2000.00000000000001     84.3     30     47GO:0005622; C:intracellular; IEA:InterPro.
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0035556; P:intracellular signal transduction; IEA:InterPro.
57P38339    666   RGD1_YEAST RHO GTPase-activating protein RGD1...1970.00000000000001     83.6     29     51GO:0030479; C:actin cortical patch; IDA:SGD.::GO:0005933; C:cellular bud; IDA:SGD.::GO:0043332; C:mating projection tip; IDA:SGD.
GO:0080025; F:phosphatidylinositol-3,5-bisphosphate binding; IMP:SGD.::GO:0032266; F:phosphatidylinositol-3-phosphate binding; IMP:SGD.::GO:0005546; F:phosphatidylinositol-4,5-bisphosphate binding; IDA:SGD.::GO:0070273; F:phosphatidylinositol-4-phosphate binding; IMP:SGD.::GO:0010314; F:phosphatidylinositol-5-phosphate binding; IMP:SGD.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0005100; F:Rho GTPase activator activity; IDA:SGD.
GO:0007231; P:osmosensory signaling pathway; IGI:SGD.::GO:0001101; P:response to acid; IMP:SGD.
58Q9V9S7    1866   SYDE_DROME Rho GTPase-activating protein 100F...1780.00000000000002     83.6     32     48GO:0005622; C:intracellular; IEA:InterPro.::GO:0048786; C:presynaptic active zone; IDA:FlyBase.
GO:0005100; F:Rho GTPase activator activity; ISS:UniProtKB.
GO:0032862; P:activation of Rho GTPase activity; ISS:UniProtKB.::GO:0048789; P:cytoskeletal matrix organization at active zone; IMP:FlyBase.::GO:0048790; P:maintenance of presynaptic active zone structure; IMP:FlyBase.::GO:0007165; P:signal transduction; IEA:InterPro.
59Q63358    1980   MYO9B_RAT Unconventional myosin-IXb OS=Rattus...1810.00000000000002     83.6     32     50GO:0005884; C:actin filament; IDA:RGD.::GO:0005938; C:cell cortex; IEA:UniProtKB-SubCell.::GO:0030027; C:lamellipodium; IDA:RGD.::GO:0016459; C:myosin complex; IEA:UniProtKB-KW.::GO:0048471; C:perinuclear region of cytoplasm; IDA:RGD.::GO:0001726; C:ruffle; IDA:RGD.::GO:0005625; C:soluble fraction; IDA:RGD.
GO:0051015; F:actin filament binding; IDA:RGD.::GO:0030898; F:actin-dependent ATPase activity; IDA:RGD.::GO:0043531; F:ADP binding; IDA:RGD.::GO:0005524; F:ATP binding; IDA:RGD.::GO:0043008; F:ATP-dependent protein binding; IDA:RGD.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0003774; F:motor activity; IEA:InterPro.::GO:0005100; F:Rho GTPase activator activity; IMP:RGD.::GO:0008270; F:zinc ion binding; IDA:RGD.
GO:0007266; P:Rho protein signal transduction; IDA:RGD.
60Q5PQJ5    1266   RHG29_RAT Rho GTPase-activating protein 29 OS...2000.00000000000002     83.6     30     47GO:0005622; C:intracellular; IEA:InterPro.
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0035556; P:intracellular signal transduction; IEA:InterPro.
61Q6GPD0    1940   RHG32_XENLA Rho GTPase-activating protein 32 ...2120.00000000000002     83.6     25     51GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.
GO:0007165; P:signal transduction; IEA:InterPro.
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