Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YER155C
Length:
2167
Number of sequences:
5887
Description:
YER155C BEM2 SGDID:S000000957, Chr V from 482848-476345, Genome Release 64-1-1, reverse complement, Verified ORF, "Rho GTPase activating protein (RhoGAP) involved in the control of cytoskeleton organization and cellular morphogenesis; required for bud emergence"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
151B9VTT2    1091   RHG07_CANFA Rho GTPase-activating protein 7 O...1720.000001     58.2     25     45GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
GO:0007165; P:signal transduction; IEA:InterPro.
152Q54C77    1186   Y3184_DICDI Probable inactive serine/threonin...1800.000001     58.2     27     48GO:0005622; C:intracellular; IEA:InterPro.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0004672; F:protein kinase activity; IEA:InterPro.
GO:0007165; P:signal transduction; IEA:InterPro.
153Q9R0Z9    1092   RHG07_MOUSE Rho GTPase-activating protein 7 O...1800.000001     57.8     26     47GO:0005737; C:cytoplasm; NAS:UniProtKB.
GO:0005100; F:Rho GTPase activator activity; NAS:UniProtKB.
GO:0030036; P:actin cytoskeleton organization; IMP:MGI.::GO:0048041; P:focal adhesion assembly; IMP:MGI.::GO:0030900; P:forebrain development; IMP:MGI.::GO:0003007; P:heart morphogenesis; IMP:MGI.::GO:0021575; P:hindbrain morphogenesis; IMP:MGI.::GO:0008285; P:negative regulation of cell proliferation; ISS:UniProtKB.::GO:0001843; P:neural tube closure; IMP:MGI.::GO:0007165; P:signal transduction; IEA:InterPro.
154Q91Z67    1071   FNBP2_MOUSE SLIT-ROBO Rho GTPase-activating p...1570.000001     57.8     29     46GO:0005743; C:mitochondrial inner membrane; IDA:MGI.
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
GO:0007165; P:signal transduction; IEA:InterPro.
155P27986    724   P85A_HUMAN Phosphatidylinositol 3-kinase regu...1540.000002     57     29     54GO:0005943; C:1-phosphatidylinositol-4-phosphate 3-kinase, class IA complex; ISS:UniProtKB.::GO:0005886; C:plasma membrane; TAS:Reactome.
GO:0005545; F:1-phosphatidylinositol binding; NAS:UniProtKB.::GO:0043125; F:ErbB-3 class receptor binding; IDA:UniProtKB.::GO:0043559; F:insulin binding; IDA:UniProtKB.::GO:0005158; F:insulin receptor binding; IPI:UniProtKB.::GO:0043560; F:insulin receptor substrate binding; ISS:BHF-UCL.::GO:0005159; F:insulin-like growth factor receptor binding; IPI:UniProtKB.::GO:0005168; F:neurotrophin TRKA receptor binding; IPI:UniProtKB.::GO:0035014; F:phosphatidylinositol 3-kinase regulator activity; ISS:UniProtKB.::GO:0019903; F:protein phosphatase binding; IPI:UniProtKB.
GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.::GO:0008543; P:fibroblast growth factor receptor signaling pathway; TAS:Reactome.::GO:0060396; P:growth hormone receptor signaling pathway; IDA:BHF-UCL.::GO:0008286; P:insulin receptor signaling pathway; IPI:UniProtKB.::GO:0048009; P:insulin-like growth factor receptor signaling pathway; IPI:UniProtKB.::GO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW.::GO:0050900; P:leukocyte migration; TAS:Reactome.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0014065; P:phosphatidylinositol 3-kinase cascade; IDA:BHF-UCL.::GO:0046854; P:phosphatidylinositol phosphorylation; ISS:UniProtKB.::GO:0030168; P:platelet activation; TAS:Reactome.::GO:0090004; P:positive regulation of establishment of protein localization in plasma membrane; ISS:BHF-UCL.::GO:0046326; P:positive regulation of glucose import; ISS:BHF-UCL.::GO:0031295; P:T cell costimulation; TAS:Reactome.::GO:0050852; P:T cell receptor signaling pathway; TAS:Reactome.
156Q9P2N2    729   RHG28_HUMAN Rho GTPase-activating protein 28 ...1850.000002     56.6     25     44GO:0005829; C:cytosol; TAS:Reactome.::GO:0005634; C:nucleus; IDA:HPA.
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.
157Q553X3    799   GACI_DICDI Rho GTPase-activating protein gacI...2330.000002     56.6     21     42GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
GO:0007165; P:signal transduction; IEA:InterPro.
158O14014    969   RGA3_SCHPO Probable Rho-type GTPase-activatin...2000.000002     56.6     23     48GO:0000935; C:barrier septum; IDA:PomBase.::GO:0051285; C:cell cortex of cell tip; IDA:PomBase.::GO:0032153; C:cell division site; IDA:PomBase.::GO:0005829; C:cytosol; IDA:PomBase.
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0035556; P:intracellular signal transduction; IEA:InterPro.
159Q8N103    731   TAGAP_HUMAN T-cell activation Rho GTPase-acti...2530.000003     56.2     25     43GO:0005829; C:cytosol; TAS:Reactome.
GO:0005085; F:guanyl-nucleotide exchange factor activity; IEA:UniProtKB-KW.
GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.
160Q9P2F6    1191   RHG20_HUMAN Rho GTPase-activating protein 20 ...1730.000005     55.8     25     47GO:0005829; C:cytosol; TAS:Reactome.
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.
GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.
161Q9NYF5    915   FA13B_HUMAN Protein FAM13B OS=Homo sapiens (H...1720.000005     55.8     27     48GO:0005829; C:cytosol; TAS:Reactome.
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.
162P26450    724   P85A_MOUSE Phosphatidylinositol 3-kinase regu...1670.000008     55.1     29     51GO:0005943; C:1-phosphatidylinositol-4-phosphate 3-kinase, class IA complex; ISS:UniProtKB.
GO:0016303; F:1-phosphatidylinositol-3-kinase activity; TAS:MGI.::GO:0043125; F:ErbB-3 class receptor binding; ISS:UniProtKB.::GO:0005158; F:insulin receptor binding; ISS:UniProtKB.::GO:0043560; F:insulin receptor substrate binding; IPI:UniProtKB.::GO:0005159; F:insulin-like growth factor receptor binding; ISS:UniProtKB.
GO:0030183; P:B cell differentiation; IMP:MGI.::GO:0034644; P:cellular response to UV; IMP:MGI.::GO:0008286; P:insulin receptor signaling pathway; ISS:UniProtKB.::GO:0048009; P:insulin-like growth factor receptor signaling pathway; ISS:UniProtKB.::GO:0043066; P:negative regulation of apoptotic process; IDA:MGI.::GO:0001953; P:negative regulation of cell-matrix adhesion; IGI:MGI.::GO:0045671; P:negative regulation of osteoclast differentiation; IGI:MGI.::GO:0051531; P:NFAT protein import into nucleus; IMP:MGI.::GO:0043065; P:positive regulation of apoptotic process; IMP:MGI.::GO:0030335; P:positive regulation of cell migration; IGI:MGI.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IMP:MGI.::GO:0006468; P:protein phosphorylation; IDA:MGI.
163Q99J31    802   OPHN1_MOUSE Oligophrenin-1 OS=Mus musculus (M...1670.000008     55.1     28     45GO:0015629; C:actin cytoskeleton; IDA:MGI.::GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0043197; C:dendritic spine; IEA:UniProtKB-SubCell.::GO:0043195; C:terminal button; IDA:MGI.
GO:0003779; F:actin binding; IDA:MGI.::GO:0008093; F:cytoskeletal adaptor activity; IEA:InterPro.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005100; F:Rho GTPase activator activity; IMP:MGI.::GO:0017124; F:SH3 domain binding; IEA:InterPro.
GO:0030036; P:actin cytoskeleton organization; IDA:MGI.::GO:0046847; P:filopodium assembly; IEA:InterPro.::GO:0007399; P:nervous system development; IEA:UniProtKB-KW.::GO:0030100; P:regulation of endocytosis; IMP:MGI.::GO:0051966; P:regulation of synaptic transmission, glutamatergic; IMP:MGI.::GO:0007165; P:signal transduction; IEA:InterPro.::GO:0048488; P:synaptic vesicle endocytosis; IMP:MGI.
164A7E300    1112   RHG07_BOVIN Rho GTPase-activating protein 7 O...1720.000008     55.1     24     47GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
GO:0007165; P:signal transduction; IEA:InterPro.
165Q07960    439   RHG01_HUMAN Rho GTPase-activating protein 1 O...1890.000009     54.3     24     47GO:0005829; C:cytosol; TAS:Reactome.::GO:0043231; C:intracellular membrane-bounded organelle; IDA:HPA.
GO:0017124; F:SH3 domain binding; IEA:UniProtKB-KW.::GO:0005070; F:SH3/SH2 adaptor activity; TAS:ProtInc.
GO:0007266; P:Rho protein signal transduction; TAS:ProtInc.
166Q63744    1091   RHG07_RAT Rho GTPase-activating protein 7 OS=...1800.00001     54.7     23     46GO:0005737; C:cytoplasm; NAS:UniProtKB.
GO:0043274; F:phospholipase binding; IPI:RGD.::GO:0005100; F:Rho GTPase activator activity; IDA:RGD.::GO:0017166; F:vinculin binding; IPI:RGD.
GO:0007202; P:activation of phospholipase C activity; IDA:RGD.::GO:0032869; P:cellular response to insulin stimulus; IEP:RGD.::GO:0007010; P:cytoskeleton organization; NAS:UniProtKB.::GO:0008285; P:negative regulation of cell proliferation; ISS:UniProtKB.::GO:0007266; P:Rho protein signal transduction; NAS:RGD.
167Q3KRB8    267   RHGBB_HUMAN Rho GTPase-activating protein 11B...1980.00001     53.1     27     41GO:0005829; C:cytosol; TAS:Reactome.
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.
168Q63787    724   P85A_RAT Phosphatidylinositol 3-kinase regula...1820.00001     54.3     27     51GO:0005943; C:1-phosphatidylinositol-4-phosphate 3-kinase, class IA complex; ISS:UniProtKB.::GO:0005634; C:nucleus; IDA:RGD.::GO:0005886; C:plasma membrane; IDA:RGD.::GO:0005625; C:soluble fraction; IDA:RGD.::GO:0019717; C:synaptosome; IDA:RGD.
GO:0016303; F:1-phosphatidylinositol-3-kinase activity; TAS:RGD.::GO:0046935; F:1-phosphatidylinositol-3-kinase regulator activity; IDA:RGD.::GO:0051117; F:ATPase binding; IPI:RGD.::GO:0005516; F:calmodulin binding; IPI:RGD.::GO:0043125; F:ErbB-3 class receptor binding; ISS:UniProtKB.::GO:0030331; F:estrogen receptor binding; IPI:RGD.::GO:0005158; F:insulin receptor binding; ISS:UniProtKB.::GO:0043560; F:insulin receptor substrate binding; ISS:UniProtKB.::GO:0005159; F:insulin-like growth factor receptor binding; ISS:UniProtKB.::GO:0043548; F:phosphatidylinositol 3-kinase binding; IPI:RGD.::GO:0051219; F:phosphoprotein binding; IPI:RGD.::GO:0008022; F:protein C-terminus binding; IDA:RGD.::GO:0019904; F:protein domain specific binding; IPI:RGD.::GO:0019901; F:protein kinase binding; IPI:RGD.::GO:0030971; F:receptor tyrosine kinase binding; IPI:RGD.::GO:0031625; F:ubiquitin protein ligase binding; IPI:RGD.
GO:0071398; P:cellular response to fatty acid; IEP:RGD.::GO:0006006; P:glucose metabolic process; IMP:RGD.::GO:0008286; P:insulin receptor signaling pathway; ISS:UniProtKB.::GO:0048009; P:insulin-like growth factor receptor signaling pathway; ISS:UniProtKB.::GO:0045776; P:negative regulation of blood pressure; IMP:RGD.::GO:0022408; P:negative regulation of cell-cell adhesion; IMP:RGD.::GO:0010459; P:negative regulation of heart rate; IMP:RGD.::GO:0045861; P:negative regulation of proteolysis; IMP:RGD.::GO:0048662; P:negative regulation of smooth muscle cell proliferation; IMP:RGD.::GO:0045768; P:positive regulation of anti-apoptosis; IMP:RGD.::GO:0030335; P:positive regulation of cell migration; IMP:RGD.::GO:0045663; P:positive regulation of myoblast differentiation; IMP:RGD.::GO:0001934; P:positive regulation of protein phosphorylation; IMP:RGD.::GO:0043200; P:response to amino acid stimulus; IEP:RGD.::GO:0051591; P:response to cAMP; IDA:RGD.::GO:0071548; P:response to dexamethasone stimulus; IEP:RGD.::GO:0042493; P:response to drug; IEP:RGD.::GO:0032355; P:response to estradiol stimulus; IEP:RGD.::GO:0045471; P:response to ethanol; IEP:RGD.::GO:0009750; P:response to fructose stimulus; IEP:RGD.::GO:0070848; P:response to growth factor stimulus; IEP:RGD.::GO:0010040; P:response to iron(II) ion; IEP:RGD.::GO:0007584; P:response to nutrient; IEP:RGD.::GO:0032570; P:response to progesterone stimulus; IEP:RGD.::GO:0033574; P:response to testosterone stimulus; IEP:RGD.::GO:0001878; P:response to yeast; IEP:RGD.
169Q80Y19    987   RHGBA_MOUSE Rho GTPase-activating protein 11A...2110.00001     54.3     25     43GO:0005622; C:intracellular; IEA:InterPro.
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
GO:0007165; P:signal transduction; IEA:InterPro.
170O43052    1150   RGA1_SCHPO Rho-type GTPase-activating protein...2390.00002     54.3     26     42GO:0032153; C:cell division site; IDA:PomBase.::GO:0030428; C:cell septum; IEA:UniProtKB-SubCell.::GO:0051286; C:cell tip; IDA:PomBase.::GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.
GO:0005100; F:Rho GTPase activator activity; ISS:PomBase.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0051666; P:actin cortical patch localization; IMP:PomBase.::GO:0030036; P:actin cytoskeleton organization; IMP:PomBase.::GO:0071937; P:barrier septum assembly involved in cell cycle cytokinesis; IMP:PomBase.::GO:0009272; P:fungal-type cell wall biogenesis; IMP:PomBase.::GO:0008360; P:regulation of cell shape; IMP:PomBase.::GO:0007165; P:signal transduction; IEA:InterPro.
171Q8BN58    729   RHG28_MOUSE Rho GTPase-activating protein 28 ...1930.00002     53.9     23     44
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
GO:0007165; P:signal transduction; IEA:InterPro.
172Q96P48    1450   ARAP1_HUMAN Arf-GAP with Rho-GAP domain, ANK ...1560.00002     54.3     28     44GO:0005829; C:cytosol; TAS:Reactome.::GO:0032580; C:Golgi cisterna membrane; IEA:UniProtKB-SubCell.::GO:0005622; C:intracellular; IEA:InterPro.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0008060; F:ARF GTPase activator activity; IDA:UniProtKB.::GO:0005547; F:phosphatidylinositol-3,4,5-trisphosphate binding; IDA:UniProtKB.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0005100; F:Rho GTPase activator activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0030037; P:actin filament reorganization involved in cell cycle; TAS:UniProtKB.::GO:0051497; P:negative regulation of stress fiber assembly; IMP:UniProtKB.::GO:0043089; P:positive regulation of Cdc42 GTPase activity; IDA:UniProtKB.::GO:0051491; P:positive regulation of filopodium assembly; IMP:UniProtKB.::GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro.::GO:0008360; P:regulation of cell shape; IMP:UniProtKB.::GO:0051270; P:regulation of cellular component movement; IMP:UniProtKB.::GO:0007165; P:signal transduction; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.
173Q9VDG2    625   RLIP_DROME RalA-binding protein 1 OS=Drosophi...960.00002     53.5     31     55GO:0005622; C:intracellular; IEA:InterPro.
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0017160; F:Ral GTPase binding; IPI:FlyBase.
GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0006898; P:receptor-mediated endocytosis; IMP:UniProtKB.::GO:0007165; P:signal transduction; IEA:InterPro.
174B1AUC7    590   RHG36_MOUSE Rho GTPase-activating protein 36 ...1840.00002     53.5     28     46GO:0005622; C:intracellular; IEA:InterPro.
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
GO:0007165; P:signal transduction; IEA:InterPro.
175P85298    464   RHG08_HUMAN Rho GTPase-activating protein 8 O...1710.00002     53.1     24     48GO:0005829; C:cytosol; TAS:Reactome.
GO:0005515; F:protein binding; IPI:BHF-UCL.::GO:0005100; F:Rho GTPase activator activity; IDA:BHF-UCL.
GO:0070374; P:positive regulation of ERK1 and ERK2 cascade; IDA:BHF-UCL.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.
176Q8K2H3    851   FA13B_MOUSE Protein FAM13B OS=Mus musculus (M...1720.00002     53.5     27     48GO:0005622; C:intracellular; IEA:InterPro.
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
GO:0007165; P:signal transduction; IEA:InterPro.
177Q5FWK3    439   RHG01_MOUSE Rho GTPase-activating protein 1 O...1870.00003     52.8     23     47GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IDA:MGI.::GO:0001726; C:ruffle; IDA:MGI.
GO:0030675; F:Rac GTPase activator activity; IDA:MGI.::GO:0017124; F:SH3 domain binding; IEA:UniProtKB-KW.
GO:0007165; P:signal transduction; IEA:InterPro.
178Q9CXP4    425   RHG08_MOUSE Rho GTPase-activating protein 8 O...1710.00003     52.8     25     49GO:0005622; C:intracellular; IEA:InterPro.
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
GO:0007165; P:signal transduction; IEA:InterPro.
179A8WRJ2    752   RRC1_CAEBR GTPase-activating protein rrc-1 OS...2240.00003     53.1     23     42GO:0005622; C:intracellular; IEA:InterPro.
GO:0005096; F:GTPase activator activity; ISS:UniProtKB.
GO:0007165; P:signal transduction; IEA:InterPro.
180Q8UUU2    722   P85AA_XENLA Phosphatidylinositol 3-kinase reg...1780.00003     52.8     24     51GO:0005943; C:1-phosphatidylinositol-4-phosphate 3-kinase, class IA complex; ISS:UniProtKB.
GO:0043125; F:ErbB-3 class receptor binding; ISS:UniProtKB.::GO:0005158; F:insulin receptor binding; ISS:UniProtKB.::GO:0043560; F:insulin receptor substrate binding; ISS:UniProtKB.::GO:0005159; F:insulin-like growth factor receptor binding; ISS:UniProtKB.::GO:0035014; F:phosphatidylinositol 3-kinase regulator activity; ISS:UniProtKB.
GO:0008286; P:insulin receptor signaling pathway; ISS:UniProtKB.::GO:0048009; P:insulin-like growth factor receptor signaling pathway; ISS:UniProtKB.::GO:0046854; P:phosphatidylinositol phosphorylation; ISS:UniProtKB.
181Q6P4F7    1023   RHGBA_HUMAN Rho GTPase-activating protein 11A...2050.00003     52.8     29     42GO:0005829; C:cytosol; TAS:Reactome.
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.
GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.
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