Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YER144C
Length:
805
Number of sequences:
5887
Description:
YER144C UBP5 SGDID:S000000946, Chr V from 460223-457806, Genome Release 64-1-1, reverse complement, Verified ORF, "Putative ubiquitin-specific protease, closest paralog of Doa4p but has no functional overlap; concentrates at the bud neck"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
1P39944    805   UBP5_YEAST Ubiquitin carboxyl-terminal hydrol...8050     1673     100     100GO:0005935; C:cellular bud neck; IDA:SGD.::GO:0000131; C:incipient cellular bud site; IDA:SGD.
GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.::GO:0004843; F:ubiquitin-specific protease activity; TAS:SGD.
GO:0016579; P:protein deubiquitination; TAS:SGD.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
2A7TGY3    882   UBP4_VANPO Ubiquitin carboxyl-terminal hydrol...8780     669     44     59GO:0031902; C:late endosome membrane; IEA:UniProtKB-SubCell.
GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.::GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.
GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
3Q6FQF0    887   UBP4_CANGA Ubiquitin carboxyl-terminal hydrol...8900     641     42     58GO:0031902; C:late endosome membrane; IEA:UniProtKB-SubCell.
GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.::GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.
GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
4B3LGK1    926   UBP4_YEAS1 Ubiquitin carboxyl-terminal hydrol...2892e-30     132     33     51GO:0031902; C:late endosome membrane; IEA:UniProtKB-SubCell.
GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.::GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.
GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
5P32571    926   UBP4_YEAST Ubiquitin carboxyl-terminal hydrol...2892e-30     132     33     51GO:0031902; C:late endosome membrane; IEA:UniProtKB-SubCell.::GO:0005624; C:membrane fraction; IDA:SGD.::GO:0005739; C:mitochondrion; IDA:SGD.::GO:0000502; C:proteasome complex; IPI:SGD.
GO:0004175; F:endopeptidase activity; IPI:SGD.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004221; F:ubiquitin thiolesterase activity; IMP:SGD.::GO:0004843; F:ubiquitin-specific protease activity; IDA:SGD.
GO:0006897; P:endocytosis; IMP:SGD.::GO:0010995; P:free ubiquitin chain depolymerization; IDA:SGD.::GO:0016579; P:protein deubiquitination; TAS:SGD.::GO:0006275; P:regulation of DNA replication; IMP:SGD.::GO:0010992; P:ubiquitin homeostasis; IMP:SGD.::GO:0043162; P:ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway; IMP:SGD.
6A6ZY34    926   UBP4_YEAS7 Ubiquitin carboxyl-terminal hydrol...2793e-31     135     33     53GO:0031902; C:late endosome membrane; IEA:UniProtKB-SubCell.
GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.::GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.
GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
7Q9HFS7    796   UBP4_KLULA Ubiquitin carboxyl-terminal hydrol...2955e-35     147     30     50GO:0031902; C:late endosome membrane; IEA:UniProtKB-SubCell.
GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.::GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.
GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
8Q754R5    848   UBP4_ASHGO Ubiquitin carboxyl-terminal hydrol...2792e-30     132     34     53GO:0031902; C:late endosome membrane; IEA:UniProtKB-SubCell.
GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.::GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.
GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
9Q80U87    1080   UBP8_MOUSE Ubiquitin carboxyl-terminal hydrol...3613e-50     194     34     50GO:0005829; C:cytosol; IDA:UniProtKB.::GO:0031313; C:extrinsic to endosome membrane; IDA:UniProtKB.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0017124; F:SH3 domain binding; IEA:UniProtKB-KW.::GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.::GO:0004843; F:ubiquitin-specific protease activity; IDA:UniProtKB.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0007032; P:endosome organization; IMP:UniProtKB.::GO:0007265; P:Ras protein signal transduction; IPI:MGI.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
10P40818    1118   UBP8_HUMAN Ubiquitin carboxyl-terminal hydrol...3803e-49     192     33     49GO:0005829; C:cytosol; IDA:UniProtKB.::GO:0005769; C:early endosome; IDA:UniProtKB.::GO:0019897; C:extrinsic to plasma membrane; IDA:UniProtKB.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0004197; F:cysteine-type endopeptidase activity; TAS:ProtInc.::GO:0017124; F:SH3 domain binding; IEA:UniProtKB-KW.::GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.::GO:0004843; F:ubiquitin-specific protease activity; IDA:UniProtKB.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0008283; P:cell proliferation; TAS:ProtInc.::GO:0007032; P:endosome organization; IMP:UniProtKB.::GO:0071108; P:protein K48-linked deubiquitination; IDA:UniProtKB.::GO:0070536; P:protein K63-linked deubiquitination; IDA:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
11O57429    357   UBP2_CHICK Ubiquitin carboxyl-terminal hydrol...3694e-49     181     34     50GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.::GO:0004843; F:ubiquitin-specific protease activity; IDA:Roslin.
GO:0016579; P:protein deubiquitination; IDA:Roslin.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
12O60139    593   UBP4_SCHPO Probable ubiquitin carboxyl-termin...3761e-46     179     32     49GO:0032153; C:cell division site; IDA:PomBase.::GO:0005768; C:endosome; IDA:PomBase.::GO:0030133; C:transport vesicle; IDA:PomBase.
GO:0005515; F:protein binding; IPI:PomBase.::GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.::GO:0004843; F:ubiquitin-specific protease activity; IDA:PomBase.
GO:0016579; P:protein deubiquitination; IDA:PomBase.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
13Q5U349    618   UBP2_RAT Ubiquitin carboxyl-terminal hydrolas...3932e-44     173     33     49GO:0005813; C:centrosome; IDA:RGD.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.
GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004221; F:ubiquitin thiolesterase activity; IMP:UniProtKB.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0007517; P:muscle organ development; IEA:UniProtKB-KW.::GO:0048642; P:negative regulation of skeletal muscle tissue development; IDA:UniProtKB.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0045931; P:positive regulation of mitotic cell cycle; ISS:UniProtKB.::GO:0048643; P:positive regulation of skeletal muscle tissue development; IDA:UniProtKB.::GO:0016579; P:protein deubiquitination; IDA:UniProtKB.::GO:0050821; P:protein stabilization; ISS:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
14O88623    613   UBP2_MOUSE Ubiquitin carboxyl-terminal hydrol...3703e-44     172     34     50GO:0005938; C:cell cortex; IDA:MGI.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.
GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.::GO:0042802; F:identical protein binding; IDA:MGI.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004221; F:ubiquitin thiolesterase activity; ISS:UniProtKB.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0007517; P:muscle organ development; IEA:UniProtKB-KW.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0045931; P:positive regulation of mitotic cell cycle; ISS:UniProtKB.::GO:0016579; P:protein deubiquitination; ISS:UniProtKB.::GO:0050821; P:protein stabilization; ISS:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
15O75604    605   UBP2_HUMAN Ubiquitin carboxyl-terminal hydrol...3702e-43     170     33     50GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.
GO:0030332; F:cyclin binding; IPI:UniProtKB.::GO:0004197; F:cysteine-type endopeptidase activity; TAS:ProtInc.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0031625; F:ubiquitin protein ligase binding; IPI:UniProtKB.::GO:0004221; F:ubiquitin thiolesterase activity; IDA:UniProtKB.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0007517; P:muscle organ development; IEA:UniProtKB-KW.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IMP:UniProtKB.::GO:0045931; P:positive regulation of mitotic cell cycle; IMP:UniProtKB.::GO:0016579; P:protein deubiquitination; IDA:UniProtKB.::GO:0050821; P:protein stabilization; IDA:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
16Q4R6D3    373   UBP50_MACFA Putative ubiquitin carboxyl-termi...3622e-41     160     32     47
GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.::GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.
GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
17Q2KHV7    606   UBP2_BOVIN Ubiquitin carboxyl-terminal hydrol...3702e-41     164     34     50GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.
GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004221; F:ubiquitin thiolesterase activity; ISS:UniProtKB.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0007517; P:muscle organ development; IEA:UniProtKB-KW.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0045931; P:positive regulation of mitotic cell cycle; ISS:UniProtKB.::GO:0016579; P:protein deubiquitination; ISS:UniProtKB.::GO:0050821; P:protein stabilization; ISS:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
18Q2KJ72    565   UBP21_BOVIN Ubiquitin carboxyl-terminal hydro...5534e-41     162     27     44GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0019784; F:NEDD8-specific protease activity; ISS:UniProtKB.::GO:0003713; F:transcription coactivator activity; ISS:UniProtKB.::GO:0004221; F:ubiquitin thiolesterase activity; ISS:UniProtKB.::GO:0004843; F:ubiquitin-specific protease activity; ISS:UniProtKB.
GO:0016578; P:histone deubiquitination; ISS:UniProtKB.::GO:0045893; P:positive regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
19B2GUX4    565   UBP21_RAT Ubiquitin carboxyl-terminal hydrola...3795e-41     162     30     48GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0019784; F:NEDD8-specific protease activity; ISS:UniProtKB.::GO:0003713; F:transcription coactivator activity; ISS:UniProtKB.::GO:0004221; F:ubiquitin thiolesterase activity; ISS:UniProtKB.::GO:0004843; F:ubiquitin-specific protease activity; ISS:UniProtKB.
GO:0016578; P:histone deubiquitination; ISS:UniProtKB.::GO:0045893; P:positive regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
20Q9QZL6    566   UBP21_MOUSE Ubiquitin carboxyl-terminal hydro...3798e-41     162     30     47GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IC:UniProtKB.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0019784; F:NEDD8-specific protease activity; ISS:UniProtKB.::GO:0003713; F:transcription coactivator activity; IDA:UniProtKB.::GO:0004221; F:ubiquitin thiolesterase activity; IDA:UniProtKB.::GO:0004843; F:ubiquitin-specific protease activity; ISS:UniProtKB.
GO:0016578; P:histone deubiquitination; IDA:UniProtKB.::GO:0045893; P:positive regulation of transcription, DNA-dependent; IDA:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
21Q9UK80    565   UBP21_HUMAN Ubiquitin carboxyl-terminal hydro...3789e-41     162     30     48GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0019784; F:NEDD8-specific protease activity; IDA:UniProtKB.::GO:0003713; F:transcription coactivator activity; ISS:UniProtKB.::GO:0004221; F:ubiquitin thiolesterase activity; IDA:UniProtKB.::GO:0004843; F:ubiquitin-specific protease activity; IDA:UniProtKB.
GO:0016578; P:histone deubiquitination; ISS:UniProtKB.::GO:0045893; P:positive regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
22Q6P8X6    390   UBP50_MOUSE Putative ubiquitin carboxyl-termi...3625e-39     154     31     45
GO:0008234; F:cysteine-type peptidase activity; IEA:UniProtKB-KW.::GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.
GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
23Q6J1Y9    1357   UBP19_RAT Ubiquitin carboxyl-terminal hydrola...1660.000000000000006     83.2     34     49GO:0005789; C:endoplasmic reticulum membrane; ISS:UniProtKB.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.::GO:0004843; F:ubiquitin-specific protease activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0030433; P:ER-associated protein catabolic process; ISS:UniProtKB.::GO:0048642; P:negative regulation of skeletal muscle tissue development; ISS:UniProtKB.::GO:0090068; P:positive regulation of cell cycle process; IMP:UniProtKB.::GO:0016579; P:protein deubiquitination; IMP:UniProtKB.::GO:1900037; P:regulation of cellular response to hypoxia; ISS:UniProtKB.::GO:0031647; P:regulation of protein stability; IDA:UniProtKB.::GO:0034976; P:response to endoplasmic reticulum stress; ISS:UniProtKB.::GO:0014732; P:skeletal muscle atrophy; IEP:UniProtKB.
24Q3UJD6    1360   UBP19_MOUSE Ubiquitin carboxyl-terminal hydro...1660.000000000000006     83.2     34     49GO:0005829; C:cytosol; IDA:UniProtKB.::GO:0005789; C:endoplasmic reticulum membrane; ISS:UniProtKB.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.::GO:0004843; F:ubiquitin-specific protease activity; IMP:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0030433; P:ER-associated protein catabolic process; ISS:UniProtKB.::GO:0048642; P:negative regulation of skeletal muscle tissue development; IMP:UniProtKB.::GO:0090068; P:positive regulation of cell cycle process; ISS:UniProtKB.::GO:0016579; P:protein deubiquitination; ISS:UniProtKB.::GO:1900037; P:regulation of cellular response to hypoxia; ISS:UniProtKB.::GO:0031647; P:regulation of protein stability; ISS:UniProtKB.::GO:0034976; P:response to endoplasmic reticulum stress; ISS:UniProtKB.::GO:0014732; P:skeletal muscle atrophy; ISS:UniProtKB.
25O94966    1318   UBP19_HUMAN Ubiquitin carboxyl-terminal hydro...1660.000000000000009     82.4     34     49GO:0005789; C:endoplasmic reticulum membrane; IDA:UniProtKB.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.::GO:0004843; F:ubiquitin-specific protease activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0030433; P:ER-associated protein catabolic process; IDA:UniProtKB.::GO:0048642; P:negative regulation of skeletal muscle tissue development; ISS:UniProtKB.::GO:0090068; P:positive regulation of cell cycle process; ISS:UniProtKB.::GO:0016579; P:protein deubiquitination; ISS:UniProtKB.::GO:1900037; P:regulation of cellular response to hypoxia; IMP:UniProtKB.::GO:0031647; P:regulation of protein stability; ISS:UniProtKB.::GO:0034976; P:response to endoplasmic reticulum stress; IEP:UniProtKB.::GO:0014732; P:skeletal muscle atrophy; ISS:UniProtKB.
26P36026    717   UBP11_YEAST Ubiquitin carboxyl-terminal hydro...4284e-30     130     29     44
GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.::GO:0004843; F:ubiquitin-specific protease activity; IDA:SGD.
GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
27Q9Y4E8    981   UBP15_HUMAN Ubiquitin carboxyl-terminal hydro...1852e-16     87.8     31     51
GO:0004197; F:cysteine-type endopeptidase activity; TAS:ProtInc.::GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.::GO:0004843; F:ubiquitin-specific protease activity; IDA:UniProtKB.
GO:0016579; P:protein deubiquitination; IDA:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
28Q8R5H1    981   UBP15_MOUSE Ubiquitin carboxyl-terminal hydro...1857e-17     89.4     32     51GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.::GO:0004843; F:ubiquitin-specific protease activity; ISS:UniProtKB.
GO:0016579; P:protein deubiquitination; ISS:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
29Q70EL3    339   UBP50_HUMAN Inactive ubiquitin carboxyl-termi...3271e-28     122     30     45
GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.
GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
30Q9USM5    849   UBP1_SCHPO Probable ubiquitin carboxyl-termin...1642e-16     87.4     33     49GO:0005783; C:endoplasmic reticulum; IDA:PomBase.
GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.::GO:0004843; F:ubiquitin-specific protease activity; IDA:PomBase.
GO:0016579; P:protein deubiquitination; IDA:PomBase.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
31P39538    1254   UBP12_YEAST Ubiquitin carboxyl-terminal hydro...1673e-17     90.5     38     55GO:0005737; C:cytoplasm; IDA:SGD.::GO:0005634; C:nucleus; IDA:SGD.
GO:0004221; F:ubiquitin thiolesterase activity; IEA:InterPro.::GO:0004843; F:ubiquitin-specific protease activity; TAS:SGD.
GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
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