Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YER129W
Length:
1142
Number of sequences:
5887
Description:
YER129W SAK1 SGDID:S000000931, Chr V from 417281-420709, Genome Release 64-1-1, Verified ORF, "Upstream serine/threonine kinase for the SNF1 complex; partially redundant with Elm1p and Tos3p; members of this family have functional orthology with LKB1, a mammalian kinase associated with Peutz-Jeghers cancer-susceptibility syndrome"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
241Q924X7    491   STK33_MOUSE Serine/threonine-protein kinase 3...3177e-25     113     27     46GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
GO:0046777; P:protein autophosphorylation; IDA:UniProtKB.
242Q5R9Z7    970   PLK4_PONAB Serine/threonine-protein kinase PL...3117e-25     115     28     45GO:0005814; C:centriole; ISS:UniProtKB.::GO:0005730; C:nucleolus; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.::GO:0004713; F:protein tyrosine kinase activity; IEA:InterPro.
GO:0007099; P:centriole replication; ISS:UniProtKB.::GO:0046601; P:positive regulation of centriole replication; ISS:UniProtKB.::GO:0060707; P:trophoblast giant cell differentiation; ISS:UniProtKB.
243Q0V7M1    424   KPSH1_BOVIN Serine/threonine-protein kinase H...3337e-25     112     28     45GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.::GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
244Q75LR7    342   SAPK1_ORYSJ Serine/threonine-protein kinase S...3357e-25     112     27     46
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0009738; P:abscisic acid mediated signaling pathway; IEA:UniProtKB-KW.
245Q9QYK9    343   KCC1B_MOUSE Calcium/calmodulin-dependent prot...3457e-25     112     28     46GO:0005954; C:calcium- and calmodulin-dependent protein kinase complex; TAS:UniProtKB.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0004683; F:calmodulin-dependent protein kinase activity; IEA:EC.
246O70150    343   KCC1B_RAT Calcium/calmodulin-dependent protei...3458e-25     111     28     46GO:0005954; C:calcium- and calmodulin-dependent protein kinase complex; TAS:UniProtKB.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0004683; F:calmodulin-dependent protein kinase activity; IDA:RGD.
247O54748    491   STK3_RAT Serine/threonine-protein kinase 3 OS...3479e-25     113     28     47GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0035329; P:hippo signaling cascade; ISS:UniProtKB.
248Q9Y2H9    1570   MAST1_HUMAN Microtubule-associated serine/thr...3559e-25     116     28     45GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; ISS:UniProtKB.::GO:0000287; F:magnesium ion binding; ISS:UniProtKB.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.
GO:0007010; P:cytoskeleton organization; ISS:UniProtKB.::GO:0007243; P:intracellular protein kinase cascade; ISS:UniProtKB.
249Q9BYT3    514   STK33_HUMAN Serine/threonine-protein kinase 3...3159e-25     113     30     47GO:0005794; C:Golgi apparatus; IDA:HPA.::GO:0005634; C:nucleus; IDA:HPA.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.
GO:0046777; P:protein autophosphorylation; ISS:UniProtKB.
250Q03002    865   FRK1_YEAST Fatty acyl-CoA synthetase and RNA ...3429e-25     115     29     43GO:0005737; C:cytoplasm; IDA:SGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
251Q6BVA0    412   IPL1_DEBHA Spindle assembly checkpoint kinase...3799e-25     112     27     44GO:0000777; C:condensed chromosome kinetochore; IEA:UniProtKB-SubCell.::GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005819; C:spindle; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0007059; P:chromosome segregation; IEA:UniProtKB-KW.
252Q95ZQ4    626   AAPK2_CAEEL 5'-AMP-activated protein kinase c...3751e-24     114     27     46GO:0030424; C:axon; IDA:WormBase.::GO:0005737; C:cytoplasm; IDA:WormBase.::GO:0043025; C:neuronal cell body; IDA:WormBase.
GO:0004679; F:AMP-activated protein kinase activity; IDA:WormBase.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.
GO:0008340; P:determination of adult lifespan; IMP:WormBase.::GO:0051729; P:germline cell cycle switching, mitotic to meiotic cell cycle; IMP:WormBase.::GO:0018105; P:peptidyl-serine phosphorylation; IDA:WormBase.::GO:0061066; P:positive regulation of dauer larval development; IGI:WormBase.::GO:0006950; P:response to stress; IEA:UniProtKB-KW.
253Q13188    491   STK3_HUMAN Serine/threonine-protein kinase 3 ...3471e-24     112     28     47GO:0005829; C:cytosol; TAS:Reactome.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IDA:UniProtKB.::GO:0000287; F:magnesium ion binding; IDA:UniProtKB.::GO:0046983; F:protein dimerization activity; ISS:UniProtKB.::GO:0043539; F:protein serine/threonine kinase activator activity; IDA:BHF-UCL.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
GO:0006915; P:apoptotic process; TAS:UniProtKB.::GO:0035329; P:hippo signaling cascade; TAS:UniProtKB.::GO:0007243; P:intracellular protein kinase cascade; IDA:UniProtKB.::GO:0090090; P:negative regulation of canonical Wnt receptor signaling pathway; IMP:BHF-UCL.::GO:0043065; P:positive regulation of apoptotic process; ISS:UniProtKB.
254O88866    714   HUNK_MOUSE Hormonally up-regulated neu tumor-...3051e-24     114     28     46
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
255Q91YS8    374   KCC1A_MOUSE Calcium/calmodulin-dependent prot...3711e-24     111     27     46GO:0005954; C:calcium- and calmodulin-dependent protein kinase complex; TAS:UniProtKB.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0004683; F:calmodulin-dependent protein kinase activity; ISS:UniProtKB.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0006913; P:nucleocytoplasmic transport; IDA:MGI.::GO:0060999; P:positive regulation of dendritic spine development; ISS:UniProtKB.::GO:0010976; P:positive regulation of neuron projection development; ISS:UniProtKB.::GO:0046827; P:positive regulation of protein export from nucleus; IDA:MGI.::GO:0071902; P:positive regulation of protein serine/threonine kinase activity; ISS:UniProtKB.::GO:0051835; P:positive regulation of synapse structural plasticity; ISS:UniProtKB.::GO:0043393; P:regulation of protein binding; ISS:UniProtKB.::GO:0007165; P:signal transduction; IDA:MGI.
256Q68UT7    714   HUNK_PANTR Hormonally up-regulated neu tumor-...3051e-24     114     28     46
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
257Q63450    374   KCC1A_RAT Calcium/calmodulin-dependent protei...3711e-24     111     27     46GO:0005954; C:calcium- and calmodulin-dependent protein kinase complex; TAS:UniProtKB.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0004683; F:calmodulin-dependent protein kinase activity; IDA:UniProtKB.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0060999; P:positive regulation of dendritic spine development; ISS:UniProtKB.::GO:0010976; P:positive regulation of neuron projection development; ISS:UniProtKB.::GO:0071902; P:positive regulation of protein serine/threonine kinase activity; ISS:UniProtKB.::GO:0051835; P:positive regulation of synapse structural plasticity; ISS:UniProtKB.::GO:0051147; P:regulation of muscle cell differentiation; ISS:UniProtKB.::GO:0043393; P:regulation of protein binding; ISS:UniProtKB.::GO:0032880; P:regulation of protein localization; ISS:UniProtKB.
258Q7PLI7    748   DCLK_DROME Serine/threonine-protein kinase CG...3311e-24     114     28     45
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.
GO:0035556; P:intracellular signal transduction; IEA:InterPro.
259P53683    533   CDPK2_ORYSJ Calcium-dependent protein kinase ...4971e-24     113     27     44
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
260P57058    714   HUNK_HUMAN Hormonally up-regulated neu tumor-...3051e-24     114     28     46
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; TAS:ProtInc.
GO:0007275; P:multicellular organismal development; TAS:ProtInc.::GO:0007165; P:signal transduction; TAS:ProtInc.
261P11801    424   KPSH1_HUMAN Serine/threonine-protein kinase H...3331e-24     112     28     45GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.::GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; NAS:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; NAS:UniProtKB.
262Q7Y0B9    371   SAPK8_ORYSJ Serine/threonine-protein kinase S...3621e-24     111     28     45
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0009738; P:abscisic acid mediated signaling pathway; IEA:UniProtKB-KW.
263Q1ZXH2    1142   FHKB_DICDI Probable serine/threonine-protein ...3301e-24     115     28     45
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
264Q0VD22    486   STK33_BOVIN Serine/threonine-protein kinase 3...3151e-24     112     29     46GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
265Q6Z9F4    451   CIPK6_ORYSJ CBL-interacting protein kinase 6 ...3171e-24     112     28     45
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0007165; P:signal transduction; IEA:InterPro.
266P05986    398   KAPC_YEAST cAMP-dependent protein kinase type...3581e-24     111     26     46GO:0005952; C:cAMP-dependent protein kinase complex; IGI:SGD.::GO:0005737; C:cytoplasm; IDA:SGD.::GO:0005634; C:nucleus; IDA:SGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004691; F:cAMP-dependent protein kinase activity; IDA:SGD.::GO:0005515; F:protein binding; IPI:IntAct.
GO:0007005; P:mitochondrion organization; IMP:SGD.::GO:0007265; P:Ras protein signal transduction; ISS:SGD.
267Q9ZSA2    531   CDPKL_ARATH Calcium-dependent protein kinase ...3231e-24     112     29     50GO:0005886; C:plasma membrane; IDA:TAIR.::GO:0009506; C:plasmodesma; IDA:TAIR.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0019903; F:protein phosphatase binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
268P87050    775   CDR2_SCHPO Mitosis inducer protein kinase cdr...3252e-24     114     27     46GO:0071341; C:medial cortical node; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.::GO:0005816; C:spindle pole body; IDA:PomBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:PomBase.::GO:0004674; F:protein serine/threonine kinase activity; TAS:PomBase.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0010971; P:positive regulation of G2/M transition of mitotic cell cycle; IGI:PomBase.::GO:0071574; P:protein localization to medial cortex; IMP:PomBase.::GO:0071775; P:regulation of cell cycle cytokinesis; IMP:PomBase.::GO:0008361; P:regulation of cell size; IGI:PomBase.::GO:0007165; P:signal transduction; NAS:PomBase.
269A0AUV4    508   SMKY_MOUSE Sperm motility kinase Y OS=Mus mus...3212e-24     112     29     45
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
270A2VDZ4    893   PLK4_BOVIN Serine/threonine-protein kinase PL...3112e-24     114     29     46GO:0005814; C:centriole; ISS:UniProtKB.::GO:0005730; C:nucleolus; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.::GO:0004713; F:protein tyrosine kinase activity; IEA:InterPro.
GO:0007099; P:centriole replication; ISS:UniProtKB.::GO:0046601; P:positive regulation of centriole replication; ISS:UniProtKB.::GO:0060707; P:trophoblast giant cell differentiation; ISS:UniProtKB.
271Q5R8Z4    681   PAK6_PONAB Serine/threonine-protein kinase PA...3322e-24     114     27     48GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
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