UniProt_SwissProt BLAST: Single locus

Species:

Saccharomyces cerevisiae S288C

Locus:

YER125W

Length:

809

Number of sequences:

5887

Description:

YER125W RSP5 SGDID:S000000927, Chr V from 410189-412618, Genome Release 64-1-1, Verified ORF, "E3 ubiquitin ligase of the NEDD4 family; involved in regulating many cellular processes including MVB sorting, heat shock response, transcription, endocytosis, and ribosome stability; human homolog is involved in Liddle syndrome; mutant tolerates aneuploidy"

rec.	Subject	Hit Length	Description	Align.Len	E value	Bit score	% ident.	% pos.	GO associations
331	Q9UPR5	921	NAC2_HUMAN Sodium/calcium exchanger 2 OS=Homo...	81	7.9	33.9	27	44	GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; TAS:Reactome.
									GO:0005432; F:calcium:sodium antiporter activity; IEA:InterPro.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.
									GO:0007596; P:blood coagulation; TAS:Reactome.::GO:0007154; P:cell communication; IEA:InterPro.
332	Q9Z1X1	1088	ESYT1_RAT Extended synaptotagmin-1 OS=Rattus ...	78	8	33.9	28	53	GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
333	Q15283	849	RASA2_HUMAN Ras GTPase-activating protein 2 O...	78	8	33.9	23	51	GO:0043231; C:intracellular membrane-bounded organelle; IDA:HPA.::GO:0031235; C:intrinsic to internal side of plasma membrane; IBA:RefGenome.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.
									GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005099; F:Ras GTPase activator activity; IBA:RefGenome.
									GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0046580; P:negative regulation of Ras protein signal transduction; IBA:RefGenome.
334	P70610	412	DOC2B_RAT Double C2-like domain-containing pr...	95	9.2	33.1	27	45	GO:0005886; C:plasma membrane; IDA:UniProtKB.::GO:0008021; C:synaptic vesicle; IEA:InterPro.
									GO:0005544; F:calcium-dependent phospholipid binding; IDA:UniProtKB.::GO:0005215; F:transporter activity; IEA:InterPro.
									GO:0048791; P:calcium ion-dependent exocytosis of neurotransmitter; IDA:UniProtKB.::GO:0006887; P:exocytosis; IEP:RGD.::GO:0045956; P:positive regulation of calcium ion-dependent exocytosis; IDA:UniProtKB.::GO:0032024; P:positive regulation of insulin secretion; ISS:UniProtKB.::GO:0031340; P:positive regulation of vesicle fusion; IDA:UniProtKB.::GO:0008104; P:protein localization; ISS:UniProtKB.
335	P11531	3678	DMD_MOUSE Dystrophin OS=Mus musculus (Mouse)....	87	9.5	33.5	28	45	GO:0030055; C:cell-substrate junction; IDA:MGI.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0016010; C:dystrophin-associated glycoprotein complex; IDA:MGI.::GO:0045121; C:membrane raft; IDA:MGI.::GO:0005792; C:microsome; IDA:MGI.::GO:0044306; C:neuron projection terminus; IDA:MGI.::GO:0042383; C:sarcolemma; IDA:MGI.::GO:0045202; C:synapse; IDA:MGI.::GO:0030018; C:Z disc; IDA:MGI.
									GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0050998; F:nitric-oxide synthase binding; IPI:BHF-UCL.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0046716; P:muscle cell homeostasis; IMP:MGI.::GO:0045213; P:neurotransmitter receptor metabolic process; IMP:MGI.::GO:0021629; P:olfactory nerve structural organization; IMP:MGI.::GO:0006355; P:regulation of transcription, DNA-dependent; IMP:MGI.::GO:0007519; P:skeletal muscle tissue development; IMP:MGI.
336	Q9R0N3	430	SYT11_MOUSE Synaptotagmin-11 OS=Mus musculus ...	122	9.6	33.1	30	45	GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005887; C:integral to plasma membrane; IDA:MGI.::GO:0030672; C:synaptic vesicle membrane; IEA:UniProtKB-SubCell.
									GO:0005215; F:transporter activity; IEA:InterPro.
337	Q9JKS6	5085	PCLO_RAT Protein piccolo OS=Rattus norvegicus...	64	9.8	33.5	33	50	GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0045202; C:synapse; IDA:UniProtKB.
									GO:0005509; F:calcium ion binding; IDA:UniProtKB.::GO:0005544; F:calcium-dependent phospholipid binding; IDA:UniProtKB.::GO:0005522; F:profilin binding; ISS:UniProtKB.
									GO:0007010; P:cytoskeleton organization; ISS:UniProtKB.::GO:0016080; P:synaptic vesicle targeting; NAS:UniProtKB.
338	Q9QYX7	5038	PCLO_MOUSE Protein piccolo OS=Mus musculus (M...	64	9.9	33.5	33	50	GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0045202; C:synapse; IDA:UniProtKB.
									GO:0005509; F:calcium ion binding; ISS:UniProtKB.::GO:0005544; F:calcium-dependent phospholipid binding; ISS:UniProtKB.::GO:0005522; F:profilin binding; IDA:UniProtKB.
									GO:0019933; P:cAMP-mediated signaling; IDA:MGI.::GO:0007010; P:cytoskeleton organization; IDA:MGI.::GO:0030073; P:insulin secretion; IDA:MGI.::GO:0017157; P:regulation of exocytosis; IDA:MGI.::GO:0016080; P:synaptic vesicle targeting; NAS:UniProtKB.

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