Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YER125W
Length:
809
Number of sequences:
5887
Description:
YER125W RSP5 SGDID:S000000927, Chr V from 410189-412618, Genome Release 64-1-1, Verified ORF, "E3 ubiquitin ligase of the NEDD4 family; involved in regulating many cellular processes including MVB sorting, heat shock response, transcription, endocytosis, and ribosome stability; human homolog is involved in Liddle syndrome; mutant tolerates aneuploidy"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
241Q9JIR4    1615   RIMS1_RAT Regulating synaptic membrane exocyt...680.31     38.5     29     53GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0042734; C:presynaptic membrane; IDA:UniProtKB.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0019901; F:protein kinase binding; IPI:UniProtKB.::GO:0017137; F:Rab GTPase binding; IEA:InterPro.::GO:0017124; F:SH3 domain binding; IPI:RGD.
GO:0006887; P:exocytosis; IEA:UniProtKB-KW.::GO:0006886; P:intracellular protein transport; IEA:InterPro.::GO:0060291; P:long-term synaptic potentiation; IMP:RGD.::GO:0006836; P:neurotransmitter transport; IEA:UniProtKB-KW.::GO:0031632; P:positive regulation of synaptic vesicle fusion to presynaptic membrane; NAS:UniProtKB.
242Q99NE5    1463   RIMS1_MOUSE Regulating synaptic membrane exoc...680.32     38.5     29     53GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0042734; C:presynaptic membrane; ISS:UniProtKB.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0017137; F:Rab GTPase binding; IEA:InterPro.
GO:0006887; P:exocytosis; IEA:UniProtKB-KW.::GO:0006886; P:intracellular protein transport; IEA:InterPro.::GO:0006836; P:neurotransmitter transport; IEA:UniProtKB-KW.::GO:0048169; P:regulation of long-term neuronal synaptic plasticity; IMP:MGI.
243Q9LYN3    610   PMTM_ARATH Probable methyltransferase PMT22 O...610.33     38.1     34     52GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
244P24506    439   SY62_DISOM Synaptotagmin-B OS=Discopyge ommat...1400.37     37.7     29     45GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0030672; C:synaptic vesicle membrane; IEA:UniProtKB-SubCell.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005215; F:transporter activity; IEA:InterPro.
245Q3UHC7    1189   DAB2P_MOUSE Disabled homolog 2-interacting pr...690.41     38.1     29     54GO:0005737; C:cytoplasm; IBA:RefGenome.::GO:0031235; C:intrinsic to internal side of plasma membrane; IBA:RefGenome.
GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005099; F:Ras GTPase activator activity; IBA:RefGenome.
GO:0070059; P:apoptosis in response to endoplasmic reticulum stress; IMP:BHF-UCL.::GO:0071356; P:cellular response to tumor necrosis factor; IMP:BHF-UCL.::GO:0035414; P:negative regulation of catenin import into nucleus; IMP:BHF-UCL.::GO:0048147; P:negative regulation of fibroblast proliferation; IMP:BHF-UCL.::GO:0046580; P:negative regulation of Ras protein signal transduction; IBA:RefGenome.::GO:0043065; P:positive regulation of apoptotic process; IMP:BHF-UCL.
246Q9ESF1    1997   OTOF_MOUSE Otoferlin OS=Mus musculus (Mouse)....920.41     38.1     28     48GO:0016323; C:basolateral plasma membrane; IEA:UniProtKB-SubCell.::GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0030672; C:synaptic vesicle membrane; IDA:UniProtKB.
GO:0005509; F:calcium ion binding; IDA:UniProtKB.::GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0007605; P:sensory perception of sound; IEA:UniProtKB-KW.::GO:0016079; P:synaptic vesicle exocytosis; IDA:UniProtKB.
247Q9HC10    1997   OTOF_HUMAN Otoferlin OS=Homo sapiens (Human)....920.43     38.1     28     48GO:0016323; C:basolateral plasma membrane; IEA:UniProtKB-SubCell.::GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005829; C:cytosol; TAS:ProtInc.::GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; TAS:ProtInc.::GO:0005624; C:membrane fraction; TAS:ProtInc.::GO:0030672; C:synaptic vesicle membrane; ISS:UniProtKB.
GO:0005509; F:calcium ion binding; ISS:UniProtKB.
GO:0006944; P:cellular membrane fusion; TAS:ProtInc.::GO:0007605; P:sensory perception of sound; TAS:ProtInc.::GO:0016079; P:synaptic vesicle exocytosis; ISS:UniProtKB.
248Q86SS6    491   SYT9_HUMAN Synaptotagmin-9 OS=Homo sapiens (H...1431.4     36.2     26     45GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0030672; C:synaptic vesicle membrane; IEA:UniProtKB-SubCell.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005215; F:transporter activity; IEA:InterPro.
249P90980    682   KPC2_CAEEL Protein kinase C-like 2 OS=Caenorh...980.47     37.7     26     55GO:0005626; C:insoluble fraction; IDA:WormBase.::GO:0043005; C:neuron projection; IDA:WormBase.::GO:0043025; C:neuronal cell body; IDA:WormBase.::GO:0005625; C:soluble fraction; IDA:WormBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004697; F:protein kinase C activity; IEA:EC.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0035556; P:intracellular signal transduction; IEA:InterPro.
250Q9ERC5    1993   OTOF_RAT Otoferlin OS=Rattus norvegicus (Rat)...920.48     37.7     28     48GO:0016323; C:basolateral plasma membrane; IEA:UniProtKB-SubCell.::GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0030672; C:synaptic vesicle membrane; ISS:UniProtKB.
GO:0005509; F:calcium ion binding; ISS:UniProtKB.
GO:0007605; P:sensory perception of sound; IEA:UniProtKB-KW.::GO:0016079; P:synaptic vesicle exocytosis; ISS:UniProtKB.
251Q86XP0    818   PA24D_HUMAN Cytosolic phospholipase A2 delta ...1130.51     37.7     27     50GO:0030659; C:cytoplasmic vesicle membrane; IEA:UniProtKB-SubCell.::GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004623; F:phospholipase A2 activity; IEA:EC.
GO:0009395; P:phospholipid catabolic process; IEA:InterPro.
252P05129    697   KPCG_HUMAN Protein kinase C gamma type OS=Hom...990.51     37.7     29     47GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005829; C:cytosol; ISS:UniProtKB.::GO:0030425; C:dendrite; ISS:UniProtKB.::GO:0048471; C:perinuclear region of cytoplasm; ISS:UniProtKB.::GO:0005886; C:plasma membrane; ISS:UniProtKB.::GO:0045202; C:synapse; IEA:UniProtKB-KW.::GO:0019717; C:synaptosome; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004697; F:protein kinase C activity; TAS:ProtInc.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007202; P:activation of phospholipase C activity; TAS:Reactome.::GO:0008219; P:cell death; IEA:UniProtKB-KW.::GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.::GO:0008543; P:fibroblast growth factor receptor signaling pathway; TAS:Reactome.::GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0043524; P:negative regulation of neuron apoptotic process; ISS:UniProtKB.::GO:0042177; P:negative regulation of protein catabolic process; IDA:HGNC.::GO:0031397; P:negative regulation of protein ubiquitination; IDA:HGNC.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0030168; P:platelet activation; TAS:Reactome.::GO:0032425; P:positive regulation of mismatch repair; IDA:HGNC.::GO:0043278; P:response to morphine; ISS:UniProtKB.::GO:0048265; P:response to pain; ISS:UniProtKB.::GO:0007268; P:synaptic transmission; TAS:Reactome.
253P47861    386   SYT5_RAT Synaptotagmin-5 OS=Rattus norvegicus...960.55     37.4     29     49GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0055038; C:recycling endosome membrane; IEA:UniProtKB-SubCell.::GO:0030672; C:synaptic vesicle membrane; IEA:UniProtKB-SubCell.
GO:0005544; F:calcium-dependent phospholipid binding; IDA:BHF-UCL.::GO:0030276; F:clathrin binding; IDA:BHF-UCL.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0019905; F:syntaxin binding; IDA:BHF-UCL.::GO:0005215; F:transporter activity; IEA:InterPro.
GO:0017156; P:calcium ion-dependent exocytosis; NAS:RGD.
254Q5VWQ8    1189   DAB2P_HUMAN Disabled homolog 2-interacting pr...690.56     37.7     29     52GO:0005737; C:cytoplasm; IDA:BHF-UCL.::GO:0031235; C:intrinsic to internal side of plasma membrane; IBA:RefGenome.
GO:0071889; F:14-3-3 protein binding; IDA:BHF-UCL.::GO:0005123; F:death receptor binding; IPI:BHF-UCL.::GO:0031435; F:mitogen-activated protein kinase kinase kinase binding; IPI:BHF-UCL.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0042803; F:protein homodimerization activity; IPI:BHF-UCL.::GO:0051721; F:protein phosphatase 2A binding; IDA:BHF-UCL.::GO:0005099; F:Ras GTPase activator activity; ISS:BHF-UCL.::GO:0035591; F:signaling adaptor activity; IDA:BHF-UCL.
GO:0007257; P:activation of JUN kinase activity; IDA:BHF-UCL.::GO:0070059; P:apoptosis in response to endoplasmic reticulum stress; ISS:BHF-UCL.::GO:0071364; P:cellular response to epidermal growth factor stimulus; ISS:BHF-UCL.::GO:0071356; P:cellular response to tumor necrosis factor; IDA:BHF-UCL.::GO:0090090; P:negative regulation of canonical Wnt receptor signaling pathway; IMP:BHF-UCL.::GO:0035414; P:negative regulation of catenin import into nucleus; ISS:BHF-UCL.::GO:0042059; P:negative regulation of epidermal growth factor receptor signaling pathway; ISS:BHF-UCL.::GO:0010633; P:negative regulation of epithelial cell migration; TAS:BHF-UCL.::GO:0050680; P:negative regulation of epithelial cell proliferation; IMP:BHF-UCL.::GO:0010719; P:negative regulation of epithelial to mesenchymal transition; IMP:BHF-UCL.::GO:0048147; P:negative regulation of fibroblast proliferation; ISS:BHF-UCL.::GO:0043124; P:negative regulation of I-kappaB kinase/NF-kappaB cascade; IDA:BHF-UCL.::GO:0043407; P:negative regulation of MAP kinase activity; IDA:BHF-UCL.::GO:0032088; P:negative regulation of NF-kappaB transcription factor activity; IMP:BHF-UCL.::GO:0034261; P:negative regulation of Ras GTPase activity; IMP:BHF-UCL.::GO:0046580; P:negative regulation of Ras protein signal transduction; IC:BHF-UCL.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:BHF-UCL.::GO:0043065; P:positive regulation of apoptotic process; IDA:BHF-UCL.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:BHF-UCL.
255Q8TDW5    730   SYTL5_HUMAN Synaptotagmin-like protein 5 OS=H...740.56     37.4     34     50GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0017137; F:Rab GTPase binding; IEA:InterPro.
GO:0006886; P:intracellular protein transport; IEA:InterPro.
256P05128    682   KPCG_BOVIN Protein kinase C gamma type OS=Bos...990.56     37.4     29     47GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005829; C:cytosol; ISS:UniProtKB.::GO:0030425; C:dendrite; ISS:UniProtKB.::GO:0048471; C:perinuclear region of cytoplasm; ISS:UniProtKB.::GO:0005886; C:plasma membrane; ISS:UniProtKB.::GO:0045202; C:synapse; IEA:UniProtKB-KW.::GO:0019717; C:synaptosome; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004697; F:protein kinase C activity; IEA:EC.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0043524; P:negative regulation of neuron apoptotic process; ISS:UniProtKB.::GO:0043278; P:response to morphine; ISS:UniProtKB.::GO:0048265; P:response to pain; ISS:UniProtKB.
257Q80W14    870   PR40B_MOUSE Pre-mRNA-processing factor 40 hom...1200.57     37.4     19     40GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell.
GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
258Q93XX4    751   C2D61_ARATH C2 domain-containing protein At1g...1300.58     37.4     28     45GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IDA:TAIR.::GO:0005773; C:vacuole; IDA:TAIR.
259P10829    697   KPCG_RABIT Protein kinase C gamma type OS=Ory...990.58     37.4     29     47GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005829; C:cytosol; ISS:UniProtKB.::GO:0030425; C:dendrite; ISS:UniProtKB.::GO:0048471; C:perinuclear region of cytoplasm; ISS:UniProtKB.::GO:0005886; C:plasma membrane; ISS:UniProtKB.::GO:0045202; C:synapse; IEA:UniProtKB-KW.::GO:0019717; C:synaptosome; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004697; F:protein kinase C activity; IEA:EC.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0043524; P:negative regulation of neuron apoptotic process; ISS:UniProtKB.::GO:0043278; P:response to morphine; ISS:UniProtKB.::GO:0048265; P:response to pain; ISS:UniProtKB.
260A4IFJ5    749   PA24A_BOVIN Cytosolic phospholipase A2 OS=Bos...570.62     37.4     39     53GO:0016023; C:cytoplasmic membrane-bounded vesicle; IEA:UniProtKB-SubCell.
GO:0005509; F:calcium ion binding; ISS:UniProtKB.::GO:0005544; F:calcium-dependent phospholipid binding; ISS:UniProtKB.::GO:0004622; F:lysophospholipase activity; IEA:EC.::GO:0004623; F:phospholipase A2 activity; ISS:UniProtKB.
GO:0009395; P:phospholipid catabolic process; IEA:InterPro.
261P46097    422   SYT2_MOUSE Synaptotagmin-2 OS=Mus musculus (M...1400.62     37     27     45GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0042584; C:chromaffin granule membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IDA:MGI.::GO:0030672; C:synaptic vesicle membrane; IEA:UniProtKB-SubCell.::GO:0042598; C:vesicular fraction; IDA:MGI.
GO:0005509; F:calcium ion binding; IDA:MGI.::GO:0005544; F:calcium-dependent phospholipid binding; IDA:MGI.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0005215; F:transporter activity; IEA:InterPro.
262Q6P730    996   DAB2P_RAT Disabled homolog 2-interacting prot...690.63     37.4     29     52GO:0005737; C:cytoplasm; IBA:RefGenome.::GO:0031235; C:intrinsic to internal side of plasma membrane; IBA:RefGenome.
GO:0047485; F:protein N-terminus binding; IPI:RGD.::GO:0005099; F:Ras GTPase activator activity; IDA:RGD.
GO:0071364; P:cellular response to epidermal growth factor stimulus; IDA:BHF-UCL.::GO:0030308; P:negative regulation of cell growth; IDA:RGD.::GO:0042059; P:negative regulation of epidermal growth factor receptor signaling pathway; IDA:BHF-UCL.::GO:0046580; P:negative regulation of Ras protein signal transduction; IDA:RGD.
263P50392    741   PA24A_DANRE Cytosolic phospholipase A2 OS=Dan...740.64     37.4     31     55GO:0016023; C:cytoplasmic membrane-bounded vesicle; IEA:UniProtKB-SubCell.
GO:0004622; F:lysophospholipase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004623; F:phospholipase A2 activity; IEA:EC.
GO:0001541; P:ovarian follicle development; IEP:ZFIN.::GO:0009395; P:phospholipid catabolic process; IEA:InterPro.
264P63319    697   KPCG_RAT Protein kinase C gamma type OS=Rattu...990.64     37.4     28     47GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005829; C:cytosol; IDA:UniProtKB.::GO:0030425; C:dendrite; IDA:UniProtKB.::GO:0048471; C:perinuclear region of cytoplasm; IDA:UniProtKB.::GO:0005886; C:plasma membrane; IDA:UniProtKB.::GO:0045202; C:synapse; IEA:UniProtKB-KW.::GO:0019717; C:synaptosome; IDA:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004698; F:calcium-dependent protein kinase C activity; IDA:RGD.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0035556; P:intracellular signal transduction; NAS:RGD.::GO:0007611; P:learning or memory; IEP:RGD.::GO:0043524; P:negative regulation of neuron apoptotic process; IMP:UniProtKB.::GO:0046777; P:protein autophosphorylation; IDA:RGD.::GO:0043278; P:response to morphine; ISS:UniProtKB.::GO:0048265; P:response to pain; ISS:UniProtKB.::GO:0007268; P:synaptic transmission; NAS:RGD.
265P63318    697   KPCG_MOUSE Protein kinase C gamma type OS=Mus...990.64     37.4     28     47GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005829; C:cytosol; ISS:UniProtKB.::GO:0030425; C:dendrite; IDA:MGI.::GO:0005634; C:nucleus; IDA:MGI.::GO:0048471; C:perinuclear region of cytoplasm; ISS:UniProtKB.::GO:0005886; C:plasma membrane; IDA:UniProtKB.::GO:0097060; C:synaptic membrane; IDA:UniProtKB.::GO:0019717; C:synaptosome; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004697; F:protein kinase C activity; IEA:EC.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007635; P:chemosensory behavior; IMP:MGI.::GO:0060384; P:innervation; IMP:UniProtKB.::GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0043524; P:negative regulation of neuron apoptotic process; ISS:UniProtKB.::GO:0043278; P:response to morphine; IMP:UniProtKB.::GO:0048265; P:response to pain; IMP:UniProtKB.::GO:0007268; P:synaptic transmission; IMP:UniProtKB.
266Q8N9I0    419   SYT2_HUMAN Synaptotagmin-2 OS=Homo sapiens (H...1160.66     37     29     47GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0042584; C:chromaffin granule membrane; IEA:UniProtKB-SubCell.::GO:0030666; C:endocytic vesicle membrane; TAS:Reactome.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; TAS:Reactome.::GO:0030672; C:synaptic vesicle membrane; IEA:UniProtKB-SubCell.
GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0005215; F:transporter activity; IEA:InterPro.
GO:0007269; P:neurotransmitter secretion; TAS:Reactome.
267P29101    422   SYT2_RAT Synaptotagmin-2 OS=Rattus norvegicus...1400.67     37     27     45GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0042584; C:chromaffin granule membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0030672; C:synaptic vesicle membrane; TAS:RGD.
GO:0005509; F:calcium ion binding; TAS:RGD.::GO:0005544; F:calcium-dependent phospholipid binding; IDA:BHF-UCL.::GO:0019905; F:syntaxin binding; IDA:BHF-UCL.::GO:0005215; F:transporter activity; IEA:InterPro.
GO:0016079; P:synaptic vesicle exocytosis; TAS:RGD.
268Q8C0D4    838   RHG12_MOUSE Rho GTPase-activating protein 12 ...1670.7     37.4     23     37GO:0005622; C:intracellular; IEA:InterPro.
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.
GO:0007165; P:signal transduction; IEA:InterPro.
269O77793    749   PA24A_HORSE Cytosolic phospholipase A2 OS=Equ...570.77     37     37     53GO:0016023; C:cytoplasmic membrane-bounded vesicle; IEA:UniProtKB-SubCell.
GO:0005509; F:calcium ion binding; ISS:UniProtKB.::GO:0005544; F:calcium-dependent phospholipid binding; ISS:UniProtKB.::GO:0004622; F:lysophospholipase activity; IEA:EC.::GO:0004623; F:phospholipase A2 activity; ISS:UniProtKB.
GO:0009395; P:phospholipid catabolic process; IEA:InterPro.
270Q4R4U2    697   KPCG_MACFA Protein kinase C gamma type OS=Mac...990.78     37     28     47GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005829; C:cytosol; ISS:UniProtKB.::GO:0030425; C:dendrite; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; ISS:UniProtKB.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0045202; C:synapse; IEA:UniProtKB-KW.::GO:0019717; C:synaptosome; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004697; F:protein kinase C activity; IEA:EC.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0043524; P:negative regulation of neuron apoptotic process; ISS:UniProtKB.::GO:0043278; P:response to morphine; ISS:UniProtKB.::GO:0048265; P:response to pain; ISS:UniProtKB.
271O00445    386   SYT5_HUMAN Synaptotagmin-5 OS=Homo sapiens (H...1390.82     36.6     27     46GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0055038; C:recycling endosome membrane; IEA:UniProtKB-SubCell.::GO:0030672; C:synaptic vesicle membrane; IEA:UniProtKB-SubCell.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005215; F:transporter activity; IEA:InterPro.
GO:0006112; P:energy reserve metabolic process; TAS:Reactome.::GO:0050796; P:regulation of insulin secretion; TAS:Reactome.::GO:0044281; P:small molecule metabolic process; TAS:Reactome.::GO:0007268; P:synaptic transmission; TAS:ProtInc.
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