Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YER125W
Length:
809
Number of sequences:
5887
Description:
YER125W RSP5 SGDID:S000000927, Chr V from 410189-412618, Genome Release 64-1-1, Verified ORF, "E3 ubiquitin ligase of the NEDD4 family; involved in regulating many cellular processes including MVB sorting, heat shock response, transcription, endocytosis, and ribosome stability; human homolog is involved in Liddle syndrome; mutant tolerates aneuploidy"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
211P59108    548   CPNE2_MOUSE Copine-2 OS=Mus musculus (Mouse)....1360.1     39.7     29     42
212Q69ZN7    2048   MYOF_MOUSE Myoferlin OS=Mus musculus (Mouse)....1350.1     40     30     45GO:0005901; C:caveola; IDA:UniProtKB.::GO:0030659; C:cytoplasmic vesicle membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0031965; C:nuclear membrane; IEA:UniProtKB-SubCell.
GO:0005543; F:phospholipid binding; IMP:UniProtKB.
GO:0034605; P:cellular response to heat; IDA:MGI.::GO:0001778; P:plasma membrane repair; IMP:UniProtKB.::GO:0030947; P:regulation of vascular endothelial growth factor receptor signaling pathway; IMP:UniProtKB.
213A2AFR3    1320   FRPD4_MOUSE FERM and PDZ domain-containing pr...611.8     35.8     33     49GO:0005856; C:cytoskeleton; IEA:InterPro.::GO:0043197; C:dendritic spine; ISS:UniProtKB.
GO:0051835; P:positive regulation of synapse structural plasticity; ISS:UniProtKB.
214Q5RAE1    537   CPNE3_PONAB Copine-3 OS=Pongo abelii (Sumatra...1100.12     39.7     25     43
215O75131    537   CPNE3_HUMAN Copine-3 OS=Homo sapiens (Human)....1100.12     39.7     25     43GO:0005829; C:cytosol; IDA:UniProtKB.
GO:0005544; F:calcium-dependent phospholipid binding; TAS:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.::GO:0005215; F:transporter activity; TAS:ProtInc.
GO:0006629; P:lipid metabolic process; TAS:ProtInc.::GO:0016192; P:vesicle-mediated transport; TAS:ProtInc.
216Q9R0N4    523   SYT10_MOUSE Synaptotagmin-10 OS=Mus musculus ...1420.13     39.3     25     46GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0030672; C:synaptic vesicle membrane; IEA:UniProtKB-SubCell.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0046982; F:protein heterodimerization activity; IPI:UniProtKB.::GO:0042803; F:protein homodimerization activity; IDA:BHF-UCL.::GO:0005215; F:transporter activity; IEA:InterPro.
217O14065    1429   YC31_SCHPO Uncharacterized protein C962.01 OS...720.13     39.7     35     50GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0008289; F:lipid binding; ISS:PomBase.
GO:0033554; P:cellular response to stress; IEP:PomBase.
218Q9ZT46    138   PP16B_CUCMA 16 kDa phloem protein 2 OS=Cucurb...540.13     37.4     33     48
GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
GO:0006810; P:transport; IEA:UniProtKB-KW.
219O08625    523   SYT10_RAT Synaptotagmin-10 OS=Rattus norvegic...1420.14     39.3     25     46GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0030672; C:synaptic vesicle membrane; IEA:UniProtKB-SubCell.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005215; F:transporter activity; IEA:InterPro.
GO:0050803; P:regulation of synapse structure and activity; NAS:RGD.::GO:0006950; P:response to stress; IEP:RGD.
220Q9Z268    799   RASL1_MOUSE RasGAP-activating-like protein 1 ...781     36.6     33     50GO:0005737; C:cytoplasm; IBA:RefGenome.::GO:0031235; C:intrinsic to internal side of plasma membrane; IBA:RefGenome.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005099; F:Ras GTPase activator activity; IBA:RefGenome.
GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0046580; P:negative regulation of Ras protein signal transduction; IBA:RefGenome.
221Q86KB1    617   ADCB_DICDI Arrestin domain-containing protein...730.14     39.3     34     51
GO:0007165; P:signal transduction; IEA:InterPro.
222Q9ZT47    150   PP16A_CUCMA 16 kDa phloem protein 1 OS=Cucurb...540.14     37.4     33     48
GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
GO:0006810; P:transport; IEA:UniProtKB-KW.
223Q8BT60    533   CPNE3_MOUSE Copine-3 OS=Mus musculus (Mouse)....1100.15     39.3     26     44GO:0005829; C:cytosol; ISS:UniProtKB.
GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.
224Q86UR5    1692   RIMS1_HUMAN Regulating synaptic membrane exoc...680.15     39.7     29     54GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; TAS:Reactome.::GO:0042734; C:presynaptic membrane; ISS:UniProtKB.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0017137; F:Rab GTPase binding; IEA:InterPro.::GO:0005083; F:small GTPase regulator activity; TAS:UniProtKB.
GO:0017156; P:calcium ion-dependent exocytosis; TAS:UniProtKB.::GO:0006944; P:cellular membrane fusion; NAS:UniProtKB.::GO:0014047; P:glutamate secretion; TAS:Reactome.::GO:0006886; P:intracellular protein transport; IEA:InterPro.::GO:0006461; P:protein complex assembly; IDA:UniProtKB.::GO:0045055; P:regulated secretory pathway; NAS:UniProtKB.::GO:0050896; P:response to stimulus; IEA:UniProtKB-KW.::GO:0016079; P:synaptic vesicle exocytosis; TAS:UniProtKB.::GO:0007601; P:visual perception; IEA:UniProtKB-KW.
225P24505    427   SY61_DISOM Synaptotagmin-A OS=Discopyge ommat...1410.16     38.9     28     48GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0030672; C:synaptic vesicle membrane; IEA:UniProtKB-SubCell.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005215; F:transporter activity; IEA:InterPro.
226Q62746    511   SYT6_RAT Synaptotagmin-6 OS=Rattus norvegicus...1430.17     38.9     26     47GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005829; C:cytosol; ISS:UniProtKB.::GO:0016021; C:integral to membrane; ISS:UniProtKB.::GO:0000300; C:peripheral to membrane of membrane fraction; ISS:UniProtKB.::GO:0005886; C:plasma membrane; ISS:UniProtKB.::GO:0030672; C:synaptic vesicle membrane; IEA:UniProtKB-SubCell.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0019905; F:syntaxin binding; IDA:RGD.::GO:0005215; F:transporter activity; IEA:InterPro.
227Q5T7P8    510   SYT6_HUMAN Synaptotagmin-6 OS=Homo sapiens (H...1430.18     38.9     26     47GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005829; C:cytosol; ISS:UniProtKB.::GO:0016021; C:integral to membrane; ISS:UniProtKB.::GO:0097038; C:perinuclear endoplasmic reticulum; ISS:BHF-UCL.::GO:0000300; C:peripheral to membrane of membrane fraction; ISS:UniProtKB.::GO:0005886; C:plasma membrane; ISS:UniProtKB.::GO:0030672; C:synaptic vesicle membrane; IEA:UniProtKB-SubCell.
GO:0030276; F:clathrin binding; IDA:BHF-UCL.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0042803; F:protein homodimerization activity; ISS:BHF-UCL.::GO:0019905; F:syntaxin binding; IDA:BHF-UCL.::GO:0005215; F:transporter activity; IEA:InterPro.
GO:0060478; P:acrosomal vesicle exocytosis; IMP:BHF-UCL.
228A3KGK3    1992   FR1L4_MOUSE Fer-1-like protein 4 OS=Mus muscu...620.2     39.3     34     50GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
229Q25378    658   KPC1_LYTPI Protein kinase C OS=Lytechinus pic...990.2     38.9     27     49
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004697; F:protein kinase C activity; IEA:EC.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0035556; P:intracellular signal transduction; IEA:InterPro.
230Q9R0N8    511   SYT6_MOUSE Synaptotagmin-6 OS=Mus musculus (M...1430.21     38.9     26     47GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IDA:BHF-UCL.::GO:0097038; C:perinuclear endoplasmic reticulum; IDA:BHF-UCL.::GO:0000300; C:peripheral to membrane of membrane fraction; IDA:UniProtKB.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0030672; C:synaptic vesicle membrane; IEA:UniProtKB-SubCell.
GO:0048306; F:calcium-dependent protein binding; IPI:UniProtKB.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0046982; F:protein heterodimerization activity; IPI:UniProtKB.::GO:0042803; F:protein homodimerization activity; IDA:BHF-UCL.::GO:0005215; F:transporter activity; IEA:InterPro.
GO:0007340; P:acrosome reaction; IDA:HGNC.
231Q96FN4    548   CPNE2_HUMAN Copine-2 OS=Homo sapiens (Human)....1360.21     38.9     26     40
232O75400    957   PR40A_HUMAN Pre-mRNA-processing factor 40 hom...1120.22     38.9     24     44GO:0016363; C:nuclear matrix; IDA:UniProtKB.::GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell.
GO:0005515; F:protein binding; IPI:IntAct.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0016477; P:cell migration; IMP:UniProtKB.::GO:0007010; P:cytoskeleton organization; IMP:UniProtKB.::GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0008360; P:regulation of cell shape; IMP:UniProtKB.::GO:0032465; P:regulation of cytokinesis; IMP:UniProtKB.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
233Q9Y2J0    694   RP3A_HUMAN Rabphilin-3A OS=Homo sapiens (Huma...820.24     38.5     32     45GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0016020; C:membrane; IEA:InterPro.::GO:0008021; C:synaptic vesicle; IEA:InterPro.
GO:0017137; F:Rab GTPase binding; IEA:InterPro.::GO:0005215; F:transporter activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006886; P:intracellular protein transport; IEA:InterPro.
234Q5R4J5    419   SYT1_PONAB Synaptotagmin-1 OS=Pongo abelii (S...1402.1     35.4     27     44GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0042584; C:chromaffin granule membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0030672; C:synaptic vesicle membrane; IEA:UniProtKB-SubCell.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005215; F:transporter activity; IEA:InterPro.
235Q9VYD1    2313   C1716_DROME Probable histone-lysine N-methylt...1160.26     38.9     28     45GO:0005694; C:chromosome; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IDA:FlyBase.
GO:0003677; F:DNA binding; IEA:InterPro.::GO:0046975; F:histone methyltransferase activity (H3-K36 specific); IMP:FlyBase.::GO:0051219; F:phosphoprotein binding; IPI:FlyBase.
GO:0035076; P:ecdysone receptor-mediated signaling pathway; IGI:FlyBase.::GO:0002168; P:instar larval development; IMP:FlyBase.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0035220; P:wing disc development; IMP:FlyBase.
236Q7T0T9    749   PA24A_XENLA Cytosolic phospholipase A2 OS=Xen...570.27     38.5     37     54GO:0016023; C:cytoplasmic membrane-bounded vesicle; IEA:UniProtKB-SubCell.
GO:0004622; F:lysophospholipase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004623; F:phospholipase A2 activity; IEA:EC.
GO:0009395; P:phospholipid catabolic process; IEA:InterPro.
237Q06846    704   RP3A_BOVIN Rabphilin-3A OS=Bos taurus (Bovine...820.27     38.5     32     45GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0016020; C:membrane; IEA:InterPro.::GO:0008021; C:synaptic vesicle; IEA:InterPro.
GO:0017137; F:Rab GTPase binding; IEA:InterPro.::GO:0005215; F:transporter activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006886; P:intracellular protein transport; IEA:InterPro.
238Q6NWY9    871   PR40B_HUMAN Pre-mRNA-processing factor 40 hom...1090.28     38.5     19     40GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell.
GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
239B1WAZ6    749   PA24A_XENTR Cytosolic phospholipase A2 OS=Xen...570.28     38.5     37     54GO:0016023; C:cytoplasmic membrane-bounded vesicle; IEA:UniProtKB-SubCell.
GO:0004622; F:lysophospholipase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004623; F:phospholipase A2 activity; IEA:EC.
GO:0009395; P:phospholipid catabolic process; IEA:InterPro.
240A4IJ05    474   SYT17_XENTR Synaptotagmin-17 OS=Xenopus tropi...630.29     38.1     32     62GO:0016020; C:membrane; IEA:UniProtKB-SubCell.::GO:0008021; C:synaptic vesicle; IEA:InterPro.
GO:0005215; F:transporter activity; IEA:InterPro.
241Q9JIR4    1615   RIMS1_RAT Regulating synaptic membrane exocyt...680.31     38.5     29     53GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0042734; C:presynaptic membrane; IDA:UniProtKB.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0019901; F:protein kinase binding; IPI:UniProtKB.::GO:0017137; F:Rab GTPase binding; IEA:InterPro.::GO:0017124; F:SH3 domain binding; IPI:RGD.
GO:0006887; P:exocytosis; IEA:UniProtKB-KW.::GO:0006886; P:intracellular protein transport; IEA:InterPro.::GO:0060291; P:long-term synaptic potentiation; IMP:RGD.::GO:0006836; P:neurotransmitter transport; IEA:UniProtKB-KW.::GO:0031632; P:positive regulation of synaptic vesicle fusion to presynaptic membrane; NAS:UniProtKB.
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