Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YER125W
Length:
809
Number of sequences:
5887
Description:
YER125W RSP5 SGDID:S000000927, Chr V from 410189-412618, Genome Release 64-1-1, Verified ORF, "E3 ubiquitin ligase of the NEDD4 family; involved in regulating many cellular processes including MVB sorting, heat shock response, transcription, endocytosis, and ribosome stability; human homolog is involved in Liddle syndrome; mutant tolerates aneuploidy"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
181Q6PFQ7    802   RASL2_MOUSE Ras GTPase-activating protein 4 O...900.011     43.1     32     51GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.::GO:0031235; C:intrinsic to internal side of plasma membrane; IBA:RefGenome.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005099; F:Ras GTPase activator activity; IBA:RefGenome.
GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0046580; P:negative regulation of Ras protein signal transduction; IBA:RefGenome.
182Q9VCR6    608   SAV_DROME Scaffold protein salvador OS=Drosop...690.013     42.7     36     48
GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0035329; P:hippo signaling cascade; TAS:UniProtKB.::GO:0007444; P:imaginal disc development; IMP:FlyBase.::GO:0006917; P:induction of apoptosis; IMP:FlyBase.::GO:0072002; P:Malpighian tubule development; IMP:FlyBase.::GO:0008285; P:negative regulation of cell proliferation; IMP:FlyBase.::GO:0046621; P:negative regulation of organ growth; TAS:FlyBase.::GO:0045464; P:R8 cell fate specification; IMP:FlyBase.::GO:0051726; P:regulation of cell cycle; IMP:FlyBase.::GO:0048814; P:regulation of dendrite morphogenesis; IGI:FlyBase.::GO:0045570; P:regulation of imaginal disc growth; TAS:FlyBase.::GO:0010212; P:response to ionizing radiation; IMP:FlyBase.::GO:0046666; P:retinal cell programmed cell death; IMP:FlyBase.::GO:0048863; P:stem cell differentiation; IMP:FlyBase.::GO:0072089; P:stem cell proliferation; IMP:FlyBase.
183Q9FVJ3    337   AGD12_ARATH ADP-ribosylation factor GTPase-ac...760.013     42.4     32     47GO:0005794; C:Golgi apparatus; IDA:TAIR.::GO:0005886; C:plasma membrane; IDA:TAIR.::GO:0005773; C:vacuole; IDA:TAIR.
GO:0008060; F:ARF GTPase activator activity; IDA:TAIR.::GO:0005543; F:phospholipid binding; IDA:TAIR.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006886; P:intracellular protein transport; TAS:TAIR.::GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro.
184Q14CM0    1322   FRPD4_HUMAN FERM and PDZ domain-containing pr...610.65     37.4     33     51GO:0005856; C:cytoskeleton; IEA:InterPro.::GO:0043197; C:dendritic spine; IDA:UniProtKB.
GO:0005546; F:phosphatidylinositol-4,5-bisphosphate binding; IDA:UniProtKB.::GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0051835; P:positive regulation of synapse structural plasticity; IMP:UniProtKB.
185Q5DTI8    891   ESYT3_MOUSE Extended synaptotagmin-3 OS=Mus m...1140.015     42.7     33     51GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
186Q9C8S6    147   Y1322_ARATH C2 domain-containing protein At1g...740.016     40     34     47
187Q9JIS1    1555   RIMS2_RAT Regulating synaptic membrane exocyt...1030.018     42.4     25     50GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0042734; C:presynaptic membrane; IEA:UniProtKB-SubCell.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0017137; F:Rab GTPase binding; IEA:InterPro.
GO:0006887; P:exocytosis; IEA:UniProtKB-KW.::GO:0006886; P:intracellular protein transport; IEA:InterPro.::GO:0006836; P:neurotransmitter transport; IEA:UniProtKB-KW.
188Q6XYQ8    523   SYT10_HUMAN Synaptotagmin-10 OS=Homo sapiens ...1420.02     42     27     46GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0030672; C:synaptic vesicle membrane; IEA:UniProtKB-SubCell.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005215; F:transporter activity; IEA:InterPro.
189Q5RCK6    523   SYT10_PONAB Synaptotagmin-10 OS=Pongo abelii ...1420.02     42     27     46GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0030672; C:synaptic vesicle membrane; IEA:UniProtKB-SubCell.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005215; F:transporter activity; IEA:InterPro.
190Q9FGS8    1027   C2GR2_ARATH C2 and GRAM domain-containing pro...690.021     42.4     30     58GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
191O15428    100   PINL_HUMAN Putative PIN1-like protein OS=Homo...320.39     35.4     44     63
192Q9UQ26    1411   RIMS2_HUMAN Regulating synaptic membrane exoc...970.023     42     25     48GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0042734; C:presynaptic membrane; IEA:UniProtKB-SubCell.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0017137; F:Rab GTPase binding; IEA:InterPro.
GO:0006886; P:intracellular protein transport; IEA:InterPro.
193Q54E35    570   GACEE_DICDI Rho GTPase-activating protein gac...810.024     42     33     52GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.
GO:0007165; P:signal transduction; IEA:InterPro.
194Q9EQZ7    1530   RIMS2_MOUSE Regulating synaptic membrane exoc...1030.025     42     25     50GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0045202; C:synapse; IEA:UniProtKB-KW.::GO:0019717; C:synaptosome; IEA:UniProtKB-SubCell.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0017137; F:Rab GTPase binding; IEA:InterPro.
GO:0017156; P:calcium ion-dependent exocytosis; IDA:MGI.::GO:0019933; P:cAMP-mediated signaling; IDA:MGI.::GO:0030073; P:insulin secretion; IDA:MGI.::GO:0006886; P:intracellular protein transport; IEA:InterPro.::GO:0006836; P:neurotransmitter transport; IEA:UniProtKB-KW.
195Q8T498    1580   GAP2_DROME Probable Ras GTPase-activating pro...750.025     42     37     52GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.
GO:0002121; P:inter-male aggressive behavior; IMP:FlyBase.::GO:0046580; P:negative regulation of Ras protein signal transduction; ISS:UniProtKB.::GO:0007165; P:signal transduction; IEA:InterPro.
196Q4R383    163   PIN1_MACFA Peptidyl-prolyl cis-trans isomeras...310.75     35.8     42     68GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell.
GO:0003755; F:peptidyl-prolyl cis-trans isomerase activity; IEA:UniProtKB-KW.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0006457; P:protein folding; IEA:UniProtKB-KW.
197O43374    803   RASL2_HUMAN Ras GTPase-activating protein 4 O...890.032     41.6     31     53GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.::GO:0031235; C:intrinsic to internal side of plasma membrane; IBA:RefGenome.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005099; F:Ras GTPase activator activity; IBA:RefGenome.
GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0046580; P:negative regulation of Ras protein signal transduction; IBA:RefGenome.
198C9J798    803   RAS4B_HUMAN Putative Ras GTPase-activating pr...890.033     41.6     31     53GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.
GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0051056; P:regulation of small GTPase mediated signal transduction; IEA:InterPro.
199Q50L43    825   PA24D_MOUSE Cytosolic phospholipase A2 delta ...1130.035     41.6     28     52GO:0030659; C:cytoplasmic vesicle membrane; IEA:UniProtKB-SubCell.::GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004623; F:phospholipase A2 activity; IDA:MGI.
GO:0009395; P:phospholipid catabolic process; IEA:InterPro.
200P24507    537   SY63_DISOM Synaptotagmin-C OS=Discopyge ommat...631.1     36.6     37     52GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0030672; C:synaptic vesicle membrane; IEA:UniProtKB-SubCell.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005215; F:transporter activity; IEA:InterPro.
201Q920M7    470   SYT17_MOUSE Synaptotagmin-17 OS=Mus musculus ...980.05     40.8     30     52GO:0016020; C:membrane; IEA:UniProtKB-SubCell.::GO:0008021; C:synaptic vesicle; IEA:InterPro.::GO:0005802; C:trans-Golgi network; IDA:MGI.
GO:0005215; F:transporter activity; IEA:InterPro.
202Q62807    474   SYT17_RAT Synaptotagmin-17 OS=Rattus norvegic...980.054     40.4     30     52GO:0016020; C:membrane; IEA:UniProtKB-SubCell.::GO:0008021; C:synaptic vesicle; IEA:InterPro.
GO:0005215; F:transporter activity; IEA:InterPro.
203Q9BSW7    474   SYT17_HUMAN Synaptotagmin-17 OS=Homo sapiens ...980.058     40.4     30     52GO:0016020; C:membrane; IEA:UniProtKB-SubCell.::GO:0008021; C:synaptic vesicle; IEA:InterPro.
GO:0005215; F:transporter activity; IEA:InterPro.
204A0FGR9    886   ESYT3_HUMAN Extended synaptotagmin-3 OS=Homo ...960.059     40.8     31     50GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
205O95294    804   RASL1_HUMAN RasGAP-activating-like protein 1 ...530.12     39.7     30     58GO:0005737; C:cytoplasm; IBA:RefGenome.::GO:0031235; C:intrinsic to internal side of plasma membrane; IBA:RefGenome.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; TAS:ProtInc.::GO:0005099; F:Ras GTPase activator activity; IBA:RefGenome.
GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0046580; P:negative regulation of Ras protein signal transduction; IBA:RefGenome.
206Q5R8Q5    474   SYT17_PONAB Synaptotagmin-17 OS=Pongo abelii ...980.068     40     30     52GO:0016020; C:membrane; IEA:UniProtKB-SubCell.::GO:0008021; C:synaptic vesicle; IEA:InterPro.
GO:0005215; F:transporter activity; IEA:InterPro.
207Q12466    1186   TCB1_YEAST Tricalbin-1 OS=Saccharomyces cerev...1300.079     40.4     28     42GO:0032541; C:cortical endoplasmic reticulum; IDA:SGD.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005739; C:mitochondrion; IDA:SGD.::GO:0005886; C:plasma membrane; IDA:SGD.
GO:0005544; F:calcium-dependent phospholipid binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
208P34693    441   SYT1_CAEEL Synaptotagmin-1 OS=Caenorhabditis ...1410.081     40     29     49GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0030672; C:synaptic vesicle membrane; IEA:UniProtKB-SubCell.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005215; F:transporter activity; IEA:InterPro.
209P47708    681   RP3A_MOUSE Rabphilin-3A OS=Mus musculus (Mous...820.088     40     32     46GO:0030054; C:cell junction; IEA:UniProtKB-KW.
GO:0017137; F:Rab GTPase binding; IEA:InterPro.::GO:0005215; F:transporter activity; IEA:InterPro.
GO:0006886; P:intracellular protein transport; IEA:InterPro.
210P47709    684   RP3A_RAT Rabphilin-3A OS=Rattus norvegicus (R...820.091     40     32     46GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005829; C:cytosol; IDA:RGD.::GO:0019898; C:extrinsic to membrane; IDA:RGD.::GO:0043234; C:protein complex; IDA:RGD.::GO:0030141; C:secretory granule; IDA:RGD.::GO:0030672; C:synaptic vesicle membrane; IDA:RGD.::GO:0019717; C:synaptosome; IDA:RGD.
GO:0005509; F:calcium ion binding; IDA:RGD.::GO:0070679; F:inositol 1,4,5 trisphosphate binding; IDA:RGD.::GO:0042301; F:phosphate ion binding; IDA:RGD.::GO:0005546; F:phosphatidylinositol-4,5-bisphosphate binding; IDA:RGD.::GO:0032403; F:protein complex binding; IDA:RGD.::GO:0017137; F:Rab GTPase binding; IEA:InterPro.::GO:0008430; F:selenium binding; IDA:RGD.::GO:0005215; F:transporter activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IDA:RGD.
GO:0007420; P:brain development; IEP:RGD.::GO:0006886; P:intracellular protein transport; IEA:InterPro.
211P59108    548   CPNE2_MOUSE Copine-2 OS=Mus musculus (Mouse)....1360.1     39.7     29     42
records
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