Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
Home About FGC Use Cases Species List

UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YER125W
Length:
809
Number of sequences:
5887
Description:
YER125W RSP5 SGDID:S000000927, Chr V from 410189-412618, Genome Release 64-1-1, Verified ORF, "E3 ubiquitin ligase of the NEDD4 family; involved in regulating many cellular processes including MVB sorting, heat shock response, transcription, endocytosis, and ribosome stability; human homolog is involved in Liddle syndrome; mutant tolerates aneuploidy"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
121Q9EQJ9    1476   MAGI3_MOUSE Membrane-associated guanylate kin...590.49     37.7     41     54GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005923; C:tight junction; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005109; F:frizzled binding; IPI:MGI.
122Q9JK71    1470   MAGI3_RAT Membrane-associated guanylate kinas...590.89     37     39     54GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005923; C:tight junction; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
123O88382    1277   MAGI2_RAT Membrane-associated guanylate kinas...650.88     37     38     52GO:0005634; C:nucleus; ISS:UniProtKB.::GO:0048471; C:perinuclear region of cytoplasm; IDA:UniProtKB.::GO:0014069; C:postsynaptic density; IDA:UniProtKB.::GO:0043234; C:protein complex; IDA:RGD.::GO:0036057; C:slit diaphragm; IDA:UniProtKB.::GO:0019717; C:synaptosome; IEA:UniProtKB-SubCell.::GO:0005923; C:tight junction; ISS:UniProtKB.
GO:0031697; F:beta-1 adrenergic receptor binding; ISS:UniProtKB.::GO:0030165; F:PDZ domain binding; IPI:RGD.::GO:0019902; F:phosphatase binding; ISS:UniProtKB.::GO:0032403; F:protein complex binding; IPI:RGD.::GO:0030159; F:receptor signaling complex scaffold activity; ISS:UniProtKB.::GO:0004871; F:signal transducer activity; ISS:UniProtKB.::GO:0046332; F:SMAD binding; ISS:UniProtKB.::GO:0070699; F:type II activin receptor binding; ISS:UniProtKB.
GO:0003094; P:glomerular filtration; IC:UniProtKB.::GO:0072015; P:glomerular visceral epithelial cell development; IEP:UniProtKB.::GO:0071850; P:mitotic cell cycle arrest; IDA:UniProtKB.::GO:0032926; P:negative regulation of activin receptor signaling pathway; ISS:UniProtKB.::GO:0030336; P:negative regulation of cell migration; IDA:UniProtKB.::GO:0008285; P:negative regulation of cell proliferation; IDA:UniProtKB.::GO:0051898; P:negative regulation of protein kinase B signaling cascade; ISS:UniProtKB.::GO:0032516; P:positive regulation of phosphoprotein phosphatase activity; ISS:UniProtKB.::GO:0002092; P:positive regulation of receptor internalization; ISS:UniProtKB.::GO:0051291; P:protein heterooligomerization; IDA:RGD.::GO:0043113; P:receptor clustering; IDA:RGD.::GO:0060395; P:SMAD protein signal transduction; ISS:UniProtKB.
124Q9WVQ1    1275   MAGI2_MOUSE Membrane-associated guanylate kin...801     36.6     38     48GO:0005634; C:nucleus; ISS:UniProtKB.::GO:0048471; C:perinuclear region of cytoplasm; ISS:UniProtKB.::GO:0014069; C:postsynaptic density; ISS:UniProtKB.::GO:0036057; C:slit diaphragm; ISS:UniProtKB.::GO:0019717; C:synaptosome; IEA:UniProtKB-SubCell.::GO:0005923; C:tight junction; ISS:UniProtKB.
GO:0031697; F:beta-1 adrenergic receptor binding; ISS:UniProtKB.::GO:0030165; F:PDZ domain binding; ISS:UniProtKB.::GO:0019902; F:phosphatase binding; ISS:UniProtKB.::GO:0030159; F:receptor signaling complex scaffold activity; ISS:UniProtKB.::GO:0004871; F:signal transducer activity; IPI:MGI.::GO:0046332; F:SMAD binding; IPI:UniProtKB.::GO:0070699; F:type II activin receptor binding; IPI:UniProtKB.
GO:0072015; P:glomerular visceral epithelial cell development; ISS:UniProtKB.::GO:0071850; P:mitotic cell cycle arrest; ISS:UniProtKB.::GO:0032926; P:negative regulation of activin receptor signaling pathway; IDA:UniProtKB.::GO:0030336; P:negative regulation of cell migration; ISS:UniProtKB.::GO:0008285; P:negative regulation of cell proliferation; ISS:UniProtKB.::GO:0051898; P:negative regulation of protein kinase B signaling cascade; ISS:UniProtKB.::GO:0032516; P:positive regulation of phosphoprotein phosphatase activity; ISS:UniProtKB.::GO:0002092; P:positive regulation of receptor internalization; ISS:UniProtKB.::GO:0051291; P:protein heterooligomerization; ISS:UniProtKB.::GO:0043113; P:receptor clustering; ISS:UniProtKB.::GO:0060395; P:SMAD protein signal transduction; IDA:UniProtKB.
125Q86UL8    1455   MAGI2_HUMAN Membrane-associated guanylate kin...801.2     36.6     38     48GO:0005634; C:nucleus; IDA:UniProtKB.::GO:0048471; C:perinuclear region of cytoplasm; ISS:UniProtKB.::GO:0014069; C:postsynaptic density; ISS:UniProtKB.::GO:0036057; C:slit diaphragm; ISS:UniProtKB.::GO:0019717; C:synaptosome; IEA:UniProtKB-SubCell.::GO:0005923; C:tight junction; IDA:UniProtKB.
GO:0031697; F:beta-1 adrenergic receptor binding; IPI:UniProtKB.::GO:0019902; F:phosphatase binding; IPI:UniProtKB.::GO:0030159; F:receptor signaling complex scaffold activity; IDA:UniProtKB.::GO:0046332; F:SMAD binding; ISS:UniProtKB.::GO:0070699; F:type II activin receptor binding; ISS:UniProtKB.
GO:0072015; P:glomerular visceral epithelial cell development; ISS:UniProtKB.::GO:0071850; P:mitotic cell cycle arrest; ISS:UniProtKB.::GO:0032926; P:negative regulation of activin receptor signaling pathway; ISS:UniProtKB.::GO:0030336; P:negative regulation of cell migration; ISS:UniProtKB.::GO:0008285; P:negative regulation of cell proliferation; ISS:UniProtKB.::GO:0051898; P:negative regulation of protein kinase B signaling cascade; IDA:UniProtKB.::GO:0003402; P:planar cell polarity pathway involved in axis elongation; NAS:UniProtKB.::GO:0032516; P:positive regulation of phosphoprotein phosphatase activity; IDA:UniProtKB.::GO:0002092; P:positive regulation of receptor internalization; IDA:UniProtKB.::GO:0051291; P:protein heterooligomerization; ISS:UniProtKB.::GO:0043113; P:receptor clustering; ISS:UniProtKB.::GO:0060395; P:SMAD protein signal transduction; ISS:UniProtKB.
126Q6DJR2    1171   WWC2_XENTR Protein WWC2 OS=Xenopus tropicalis...340.36     38.1     44     62
127Q803A8    412   WWOX_DANRE WW domain-containing oxidoreductas...320.78     36.6     47     66GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
128Q5TCQ9    1506   MAGI3_HUMAN Membrane-associated guanylate kin...560.018     42.4     41     54GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005923; C:tight junction; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004385; F:guanylate kinase activity; NAS:UniProtKB.::GO:0005515; F:protein binding; IPI:IntAct.
GO:0006915; P:apoptotic process; NAS:UniProtKB.::GO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW.::GO:0035556; P:intracellular signal transduction; NAS:UniProtKB.
129O43581    403   SYT7_HUMAN Synaptotagmin-7 OS=Homo sapiens (H...850.068     40     29     49GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0030672; C:synaptic vesicle membrane; IEA:UniProtKB-SubCell.
GO:0005215; F:transporter activity; IEA:InterPro.
130Q9R0N7    403   SYT7_MOUSE Synaptotagmin-7 OS=Mus musculus (M...863.4     34.7     30     50GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005764; C:lysosome; IDA:MGI.::GO:0030672; C:synaptic vesicle membrane; IEA:UniProtKB-SubCell.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005215; F:transporter activity; IEA:InterPro.
GO:0001778; P:plasma membrane repair; IDA:MGI.
131Q9H4B6    383   SAV1_HUMAN Protein salvador homolog 1 OS=Homo...321.9     35.4     50     63GO:0005829; C:cytosol; TAS:Reactome.::GO:0005634; C:nucleus; IDA:UniProtKB.
GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0035329; P:hippo signaling cascade; ISS:UniProtKB.
132O95817    575   BAG3_HUMAN BAG family molecular chaperone reg...530.006     43.9     42     57GO:0005829; C:cytosol; IDA:MGI.::GO:0005886; C:plasma membrane; IDA:HPA.
GO:0051087; F:chaperone binding; IEA:InterPro.
GO:0006916; P:anti-apoptosis; NAS:UniProtKB.::GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0006457; P:protein folding; NAS:UniProtKB.
133Q54T86    568   DWWA_DICDI WW domain-containing protein A OS=...420.51     37.4     36     62GO:0005938; C:cell cortex; IDA:dictyBase.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
GO:0005516; F:calmodulin binding; IDA:dictyBase.::GO:0004842; F:ubiquitin-protein ligase activity; IBA:RefGenome.
GO:0007015; P:actin filament organization; IMP:dictyBase.::GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0000910; P:cytokinesis; IMP:dictyBase.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IBA:RefGenome.
134B4K6I9    1264   KIBRA_DROMO Protein kibra OS=Drosophila mojav...346     34.3     38     62GO:0016324; C:apical plasma membrane; IEA:UniProtKB-SubCell.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0035330; P:regulation of hippo signaling cascade; ISS:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
135Q8VEB2    386   SAV1_MOUSE Protein salvador homolog 1 OS=Mus ...322.1     35.4     50     63GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0001942; P:hair follicle development; IMP:MGI.::GO:0035329; P:hippo signaling cascade; IMP:UniProtKB.::GO:0060575; P:intestinal epithelial cell differentiation; IMP:MGI.::GO:0030216; P:keratinocyte differentiation; IMP:MGI.::GO:0060487; P:lung epithelial cell differentiation; IMP:MGI.::GO:0060044; P:negative regulation of cardiac muscle cell proliferation; IMP:MGI.::GO:0050680; P:negative regulation of epithelial cell proliferation; IMP:MGI.::GO:0043065; P:positive regulation of apoptotic process; IMP:MGI.::GO:2000036; P:regulation of stem cell maintenance; IMP:MGI.::GO:0060412; P:ventricular septum morphogenesis; IMP:MGI.
136Q6IQ23    1121   PKHA7_HUMAN Pleckstrin homology domain-contai...384.2     34.7     39     55GO:0005813; C:centrosome; IDA:UniProtKB.::GO:0005634; C:nucleus; IDA:HPA.::GO:0005915; C:zonula adherens; IDA:UniProtKB.
GO:0070097; F:delta-catenin binding; IDA:UniProtKB.::GO:0005543; F:phospholipid binding; IEA:InterPro.
GO:0090136; P:epithelial cell-cell adhesion; IMP:UniProtKB.::GO:0045218; P:zonula adherens maintenance; IMP:UniProtKB.
137Q62768    1735   UN13A_RAT Protein unc-13 homolog A OS=Rattus ...1430.00001     53.1     27     45GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0060076; C:excitatory synapse; IDA:BHF-UCL.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0042734; C:presynaptic membrane; IDA:RGD.::GO:0043234; C:protein complex; IDA:RGD.::GO:0019717; C:synaptosome; IDA:RGD.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0019904; F:protein domain specific binding; IDA:RGD.::GO:0046982; F:protein heterodimerization activity; IDA:RGD.::GO:0042803; F:protein homodimerization activity; IDA:RGD.::GO:0000149; F:SNARE binding; IDA:RGD.
GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0060291; P:long-term synaptic potentiation; IMP:RGD.::GO:0016082; P:synaptic vesicle priming; IDA:RGD.
138Q9UPW8    1703   UN13A_HUMAN Protein unc-13 homolog A OS=Homo ...1430.00001     53.1     27     45GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0042734; C:presynaptic membrane; IEA:UniProtKB-SubCell.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0035556; P:intracellular signal transduction; IEA:InterPro.
139A4V8B4    387   SAV1_RAT Protein salvador homolog 1 OS=Rattus...322.6     35     50     63GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0035329; P:hippo signaling cascade; ISS:UniProtKB.
140Q4KUS2    1712   UN13A_MOUSE Protein unc-13 homolog A OS=Mus m...1430.00001     52.8     27     45GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0042734; C:presynaptic membrane; IEA:UniProtKB-SubCell.
GO:0019992; F:diacylglycerol binding; IDA:MGI.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0050435; P:beta-amyloid metabolic process; IMP:MGI.::GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0048172; P:regulation of short-term neuronal synaptic plasticity; IMP:MGI.::GO:0035249; P:synaptic transmission, glutamatergic; IMP:MGI.::GO:0016081; P:synaptic vesicle docking involved in exocytosis; IGI:MGI.::GO:0016188; P:synaptic vesicle maturation; IMP:MGI.
141B4M5X4    1276   KIBRA_DROVI Protein kibra OS=Drosophila viril...300.24     38.9     50     63GO:0016324; C:apical plasma membrane; IEA:UniProtKB-SubCell.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0035330; P:regulation of hippo signaling cascade; ISS:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
142Q9JLV1    577   BAG3_MOUSE BAG family molecular chaperone reg...330.015     42.4     55     70
GO:0051087; F:chaperone binding; IEA:InterPro.
GO:0006916; P:anti-apoptosis; IDA:MGI.
143B4NAD3    1288   KIBRA_DROWI Protein kibra OS=Drosophila willi...340.99     37     38     65GO:0016324; C:apical plasma membrane; IEA:UniProtKB-SubCell.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0035330; P:regulation of hippo signaling cascade; ISS:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
144Q3UIL6    1118   PKHA7_MOUSE Pleckstrin homology domain-contai...382.6     35.4     39     61GO:0005813; C:centrosome; ISS:UniProtKB.::GO:0005915; C:zonula adherens; ISS:UniProtKB.
GO:0070097; F:delta-catenin binding; ISS:UniProtKB.::GO:0005543; F:phospholipid binding; IEA:InterPro.
GO:0090136; P:epithelial cell-cell adhesion; ISS:UniProtKB.::GO:0045218; P:zonula adherens maintenance; ISS:UniProtKB.
145Q0JBH9    144   ERG3_ORYSJ Elicitor-responsive protein 3 OS=O...880.00003     48.5     32     50
146Q25AG5    144   ERG3_ORYSI Elicitor-responsive protein 3 OS=O...880.00003     48.5     32     50
147B3LWS4    1271   KIBRA_DROAN Protein kibra OS=Drosophila anana...340.93     37     38     65GO:0016324; C:apical plasma membrane; IEA:UniProtKB-SubCell.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0035330; P:regulation of hippo signaling cascade; ISS:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
148Q9VLU5    409   WWOX_DROME WW domain-containing oxidoreductas...423.8     34.7     40     62GO:0005737; C:cytoplasm; IDA:UniProtKB.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:2000377; P:regulation of reactive oxygen species metabolic process; IMP:FlyBase.::GO:0010212; P:response to ionizing radiation; IMP:UniProtKB.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
149Q9GZV5    400   WWTR1_HUMAN WW domain-containing transcriptio...1020.16     38.9     33     44GO:0005829; C:cytosol; TAS:Reactome.
GO:0003713; F:transcription coactivator activity; IDA:UniProtKB.
GO:0035329; P:hippo signaling cascade; IDA:UniProtKB.::GO:0090090; P:negative regulation of canonical Wnt receptor signaling pathway; IMP:BHF-UCL.::GO:0035414; P:negative regulation of catenin import into nucleus; IMP:BHF-UCL.::GO:0006469; P:negative regulation of protein kinase activity; IMP:BHF-UCL.::GO:0001933; P:negative regulation of protein phosphorylation; IMP:BHF-UCL.::GO:0008284; P:positive regulation of cell proliferation; IDA:UniProtKB.::GO:0010718; P:positive regulation of epithelial to mesenchymal transition; IDA:UniProtKB.::GO:0060390; P:regulation of SMAD protein import into nucleus; IDA:UniProtKB.::GO:0017145; P:stem cell division; IDA:UniProtKB.::GO:0006367; P:transcription initiation from RNA polymerase II promoter; TAS:Reactome.
150Q6DN14    999   MCTP1_HUMAN Multiple C2 and transmembrane dom...861.3     36.2     29     44GO:0016021; C:integral to membrane; IDA:HGNC.::GO:0005624; C:membrane fraction; ISS:HGNC.
GO:0005509; F:calcium ion binding; IDA:HGNC.
GO:0019722; P:calcium-mediated signaling; NAS:HGNC.
151P46936    448   YAP1_CHICK Yorkie homolog OS=Gallus gallus (C...1380.011     42.7     30     43GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0044212; F:transcription regulatory region DNA binding; ISS:UniProtKB.
GO:0071480; P:cellular response to gamma radiation; ISS:UniProtKB.::GO:0006975; P:DNA damage induced protein phosphorylation; ISS:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
records
Previous ‹‹ ›› Next Total records: 338 121 - 150
Elimate unknown annotation:
Filter for keyword on hit description:
Select upper E value:
Select lower bit score:
Select lower %idenity value:
Select lower %positive value:
Taxonomic division:
Lower limit on hit length:
Lower limit on alignment length::