Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YER123W
Length:
524
Number of sequences:
5887
Description:
YER123W YCK3 SGDID:S000000925, Chr V from 404813-406387, Genome Release 64-1-1, Verified ORF, "Palmitoylated, vacuolar membrane-localized casein kinase I isoform; negatively regulates vacuole fusion during hypertonic stress via phosphorylation of Vps41p; shares essential functions with Hrr25p; regulates vesicle fusion in AP-3 pathway"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
91Q8R9T6    625   PKN1_THETN Probable serine/threonine-protein ...3250.0000000003     66.2     26     41
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008658; F:penicillin binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
92P24362    283   KRB2_VACCW Probable serine/threonine-protein ...2330.0000000003     64.3     27     41
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
93P21098    283   KRB2_VACCC Probable serine/threonine-protein ...2400.0000000005     63.9     25     39
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
94O57259    283   KRB2_VACCA Probable serine/threonine-protein ...2400.000000001     62.8     25     39
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
95Q9J509    292   V226_FOWPN Probable serine/threonine-protein ...1880.000000001     62.8     27     45
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
96Q09503    290   YQI1_CAEEL Uncharacterized protein C45G9.1 OS...2550.000000003     61.6     22     42
GO:0005524; F:ATP binding; IEA:InterPro.::GO:0004672; F:protein kinase activity; IEA:InterPro.
97Q8IV63    474   VRK3_HUMAN Inactive serine/threonine-protein ...2430.000000004     62.8     24     42GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:InterPro.::GO:0004672; F:protein kinase activity; IEA:InterPro.
98Q03407    766   PKH1_YEAST Serine/threonine-protein kinase PK...2800.00000003     60.1     25     41GO:0005829; C:cytosol; IDA:SGD.::GO:0032126; C:eisosome; IDA:SGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0033962; P:cytoplasmic mRNA processing body assembly; IGI:SGD.::GO:0006897; P:endocytosis; IMP:SGD.::GO:0000196; P:MAPK cascade involved in cell wall biogenesis; IGI:SGD.::GO:0060211; P:regulation of nuclear-transcribed mRNA poly(A) tail shortening; IGI:SGD.
99P54743    437   PKNA_MYCLE Probable serine/threonine-protein ...2580.00000004     59.3     24     41
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
100Q8NU97    469   PKN2_CORGL Serine/threonine-protein kinases p...1480.00000004     59.3     28     42
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
101Q8MYQ1    441   Y31E_CAEEL Putative serine/threonine-protein ...3090.0000001     57.8     22     41
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0040027; P:negative regulation of vulval development; IMP:WormBase.
102P65726    431   PKNA_MYCTU Probable serine/threonine-protein ...2210.0000002     57.4     25     43GO:0005829; C:cytosol; IDA:MTBBASE.::GO:0005576; C:extracellular region; IDA:MTBBASE.::GO:0005886; C:plasma membrane; IDA:MTBBASE.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:MTBBASE.::GO:0004674; F:protein serine/threonine kinase activity; IDA:MTBBASE.
GO:0040007; P:growth; IMP:MTBBASE.::GO:0043086; P:negative regulation of catalytic activity; IDA:MTBBASE.::GO:0051055; P:negative regulation of lipid biosynthetic process; IDA:MTBBASE.::GO:0043085; P:positive regulation of catalytic activity; IDA:MTBBASE.::GO:0043388; P:positive regulation of DNA binding; IDA:MTBBASE.::GO:0046777; P:protein autophosphorylation; IDA:MTBBASE.::GO:0008360; P:regulation of cell shape; IDA:MTBBASE.
103P65727    431   PKNA_MYCBO Probable serine/threonine-protein ...2210.0000002     57.4     25     43
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
104P54736    830   PKN2_MYXXA Serine/threonine-protein kinase pk...2560.0000002     57.8     24     41GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016849; F:phosphorus-oxygen lyase activity; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0009190; P:cyclic nucleotide biosynthetic process; IEA:InterPro.::GO:0035556; P:intracellular signal transduction; IEA:InterPro.
105Q03002    865   FRK1_YEAST Fatty acyl-CoA synthetase and RNA ...2650.0000003     57.4     24     42GO:0005737; C:cytoplasm; IDA:SGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
106O22040    666   ANP1_ARATH Mitogen-activated protein kinase k...2470.0000003     57     23     39
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004709; F:MAP kinase kinase kinase activity; IEA:EC.
GO:0009908; P:flower development; IGI:TAIR.::GO:0046777; P:protein autophosphorylation; IDA:TAIR.::GO:0006979; P:response to oxidative stress; IDA:TAIR.
107Q9FZ36    651   M3K2_ARATH Mitogen-activated protein kinase k...2470.0000003     57     22     39GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005874; C:microtubule; IEA:UniProtKB-KW.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004709; F:MAP kinase kinase kinase activity; IEA:EC.
GO:0043622; P:cortical microtubule organization; IMP:UniProtKB.::GO:0000910; P:cytokinesis; IGI:TAIR.
108O43077    559   MDE3_SCHPO Sporulation protein kinase mde3 OS...1940.0000006     55.8     29     46
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; ISS:PomBase.
GO:0030437; P:ascospore formation; IGI:PomBase.::GO:0007165; P:signal transduction; NAS:PomBase.
109A8XQD5    1191   DKF2_CAEBR Serine/threonine-protein kinase dk...2380.0000006     56.2     23     41GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0004697; F:protein kinase C activity; IEA:EC.
GO:0045087; P:innate immune response; IEA:UniProtKB-KW.::GO:0035556; P:intracellular signal transduction; IEA:InterPro.
110Q9BYT3    514   STK33_HUMAN Serine/threonine-protein kinase 3...2530.0000007     55.5     25     41GO:0005794; C:Golgi apparatus; IDA:HPA.::GO:0005634; C:nucleus; IDA:HPA.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.
GO:0046777; P:protein autophosphorylation; ISS:UniProtKB.
111A6QGC0    664   PRKC_STAAE Serine/threonine-protein kinase Pr...1580.000001     54.7     26     41GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008658; F:penicillin binding; IEA:InterPro.::GO:0042834; F:peptidoglycan binding; IDA:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.
GO:0071224; P:cellular response to peptidoglycan; IGI:UniProtKB.::GO:0007165; P:signal transduction; IGI:UniProtKB.::GO:0009847; P:spore germination; IGI:UniProtKB.
112Q9Y6R4    1608   M3K4_HUMAN Mitogen-activated protein kinase k...2790.000001     55.1     25     40GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004709; F:MAP kinase kinase kinase activity; TAS:ProtInc.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0007254; P:JNK cascade; TAS:ProtInc.::GO:0043507; P:positive regulation of JUN kinase activity; ISS:UniProtKB.
113O45818    1070   DKF2_CAEEL Serine/threonine-protein kinase dk...2380.000001     55.1     23     41GO:0005737; C:cytoplasm; IDA:WormBase.::GO:0016020; C:membrane; IDA:WormBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0004697; F:protein kinase C activity; IEA:EC.
GO:0050829; P:defense response to Gram-negative bacterium; IMP:WormBase.::GO:0050830; P:defense response to Gram-positive bacterium; IMP:WormBase.::GO:0045087; P:innate immune response; IEA:UniProtKB-KW.::GO:0007243; P:intracellular protein kinase cascade; IMP:WormBase.::GO:0018105; P:peptidyl-serine phosphorylation; IDA:WormBase.::GO:0045089; P:positive regulation of innate immune response; IMP:WormBase.
114O08648    1597   M3K4_MOUSE Mitogen-activated protein kinase k...2790.000001     55.1     25     39GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004709; F:MAP kinase kinase kinase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0019100; P:male germ-line sex determination; IMP:MGI.::GO:0043507; P:positive regulation of JUN kinase activity; IDA:UniProtKB.
115P51812    740   KS6A3_HUMAN Ribosomal protein S6 kinase alpha...2690.000002     54.3     26     42GO:0005829; C:cytosol; TAS:Reactome.::GO:0005654; C:nucleoplasm; TAS:Reactome.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0043027; F:cysteine-type endopeptidase inhibitor activity involved in apoptotic process; IDA:UniProtKB.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; TAS:ProtInc.
GO:0007411; P:axon guidance; TAS:Reactome.::GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0007417; P:central nervous system development; TAS:ProtInc.::GO:0045087; P:innate immune response; TAS:Reactome.::GO:0002755; P:MyD88-dependent toll-like receptor signaling pathway; TAS:Reactome.::GO:0043066; P:negative regulation of apoptotic process; TAS:UniProtKB.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0045597; P:positive regulation of cell differentiation; TAS:UniProtKB.::GO:0030307; P:positive regulation of cell growth; TAS:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IMP:BHF-UCL.::GO:0043620; P:regulation of DNA-dependent transcription in response to stress; TAS:UniProtKB.::GO:0043555; P:regulation of translation in response to stress; TAS:UniProtKB.::GO:0032496; P:response to lipopolysaccharide; ISS:UniProtKB.::GO:0001501; P:skeletal system development; TAS:ProtInc.::GO:0051403; P:stress-activated MAPK cascade; TAS:Reactome.::GO:0007268; P:synaptic transmission; TAS:Reactome.::GO:0008063; P:Toll signaling pathway; TAS:Reactome.::GO:0034130; P:toll-like receptor 1 signaling pathway; TAS:Reactome.::GO:0034134; P:toll-like receptor 2 signaling pathway; TAS:Reactome.::GO:0034138; P:toll-like receptor 3 signaling pathway; TAS:Reactome.::GO:0034142; P:toll-like receptor 4 signaling pathway; TAS:Reactome.::GO:0035666; P:TRIF-dependent toll-like receptor signaling pathway; TAS:Reactome.
116Q91819    408   AURAB_XENLA Aurora kinase A-B OS=Xenopus laev...2450.000002     53.9     24     40GO:0005813; C:centrosome; ISS:UniProtKB.::GO:0005876; C:spindle microtubule; ISS:UniProtKB.::GO:0000922; C:spindle pole; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0019894; F:kinesin binding; ISS:UniProtKB.::GO:0008017; F:microtubule binding; ISS:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0018105; P:peptidyl-serine phosphorylation; ISS:UniProtKB.::GO:0046777; P:protein autophosphorylation; ISS:UniProtKB.::GO:0090307; P:spindle assembly involved in mitosis; ISS:UniProtKB.
117P18654    740   KS6A3_MOUSE Ribosomal protein S6 kinase alpha...2690.000002     54.3     26     42GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0019901; F:protein kinase binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:MGI.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0007243; P:intracellular protein kinase cascade; IEA:InterPro.::GO:0032496; P:response to lipopolysaccharide; IMP:UniProtKB.::GO:0006950; P:response to stress; IEA:UniProtKB-KW.::GO:0002224; P:toll-like receptor signaling pathway; IMP:UniProtKB.
118Q91820    407   AURAA_XENLA Aurora kinase A-A OS=Xenopus laev...2450.000002     53.5     25     40GO:0005813; C:centrosome; IDA:UniProtKB.::GO:0005876; C:spindle microtubule; IDA:UniProtKB.::GO:0000922; C:spindle pole; IDA:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0019894; F:kinesin binding; IPI:UniProtKB.::GO:0008017; F:microtubule binding; IDA:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0018105; P:peptidyl-serine phosphorylation; IMP:UniProtKB.::GO:0046777; P:protein autophosphorylation; IMP:UniProtKB.::GO:0090307; P:spindle assembly involved in mitosis; IMP:UniProtKB.
119Q8FUI4    520   PKN2_COREF Serine/threonine-protein kinases d...1480.000002     53.9     27     41
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
120Q924X7    491   STK33_MOUSE Serine/threonine-protein kinase 3...2450.000002     53.5     25     46GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
GO:0046777; P:protein autophosphorylation; IDA:UniProtKB.
121O59790    355   ARK1_SCHPO Serine/threonine-protein kinase ar...2450.000002     53.1     23     43GO:0032133; C:chromosome passenger complex; NAS:PomBase.::GO:0000778; C:condensed nuclear chromosome kinetochore; IDA:PomBase.::GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0051233; C:spindle midzone; IDA:PomBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:PomBase.::GO:0004674; F:protein serine/threonine kinase activity; IDA:PomBase.
GO:0051315; P:attachment of spindle microtubules to kinetochore involved in mitotic sister chromatid segregation; TAS:PomBase.::GO:0033205; P:cell cycle cytokinesis; IMP:PomBase.::GO:2000775; P:histone H3-S10 phosphorylation involved in chromosome condensation; IDA:PomBase.::GO:0007094; P:mitotic cell cycle spindle assembly checkpoint; IMP:PomBase.::GO:0034501; P:protein localization to kinetochore; IGI:PomBase.::GO:0034503; P:protein localization to nucleolar rDNA repeats; IGI:PomBase.::GO:0031134; P:sister chromatid biorientation; TAS:PomBase.
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