Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YER123W
Length:
524
Number of sequences:
5887
Description:
YER123W YCK3 SGDID:S000000925, Chr V from 404813-406387, Genome Release 64-1-1, Verified ORF, "Palmitoylated, vacuolar membrane-localized casein kinase I isoform; negatively regulates vacuole fusion during hypertonic stress via phosphorylation of Vps41p; shares essential functions with Hrr25p; regulates vesicle fusion in AP-3 pathway"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
31P67827    325   KC1A_BOVIN Casein kinase I isoform alpha OS=B...3346e-93     293     46     62GO:0000777; C:condensed chromosome kinetochore; IEA:UniProtKB-SubCell.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.::GO:0016607; C:nuclear speck; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; ISS:UniProtKB.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
32Q8IHZ9    323   KC1_PLAF7 Casein kinase I OS=Plasmodium falci...3191e-92     292     47     63
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
33P40235    365   HHP1_SCHPO Casein kinase I homolog hhp1 OS=Sc...3231e-92     293     48     61GO:0032153; C:cell division site; IDA:PomBase.::GO:0005829; C:cytosol; IDA:PomBase.::GO:0033551; C:monopolin complex; ISS:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; ISS:PomBase.
GO:0051519; P:activation of bipolar cell growth; IMP:PomBase.::GO:0051455; P:attachment of spindle microtubules to kinetochore involved in homologous chromosome segregation; ISS:PomBase.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0006282; P:regulation of DNA repair; IMP:PomBase.::GO:0007165; P:signal transduction; NAS:PomBase.
34Q5BP74    415   KC1D_XENLA Casein kinase I isoform delta OS=X...3892e-92     295     43     57GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
35P48730    415   KC1D_HUMAN Casein kinase I isoform delta OS=H...3294e-92     294     47     62GO:0005813; C:centrosome; IDA:UniProtKB.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0005794; C:Golgi apparatus; IDA:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB.::GO:0048471; C:perinuclear region of cytoplasm; IDA:UniProtKB.::GO:0005886; C:plasma membrane; IDA:UniProtKB.::GO:0005876; C:spindle microtubule; IDA:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0050321; F:tau-protein kinase activity; IEA:EC.
GO:0032922; P:circadian regulation of gene expression; ISS:UniProtKB.::GO:0006281; P:DNA repair; TAS:ProtInc.::GO:0000086; P:G2/M transition of mitotic cell cycle; TAS:Reactome.::GO:0090263; P:positive regulation of canonical Wnt receptor signaling pathway; IMP:BHF-UCL.::GO:0032436; P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process; ISS:UniProtKB.::GO:0001934; P:positive regulation of protein phosphorylation; IMP:BHF-UCL.::GO:0042752; P:regulation of circadian rhythm; ISS:UniProtKB.::GO:0051225; P:spindle assembly; IDA:UniProtKB.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
36P35508    415   KC1D_BOVIN Casein kinase I isoform delta OS=B...3294e-92     294     47     62GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; ISS:UniProtKB.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0050321; F:tau-protein kinase activity; IEA:EC.
GO:0032922; P:circadian regulation of gene expression; ISS:UniProtKB.::GO:0032436; P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process; ISS:UniProtKB.::GO:0042752; P:regulation of circadian rhythm; ISS:UniProtKB.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
37Q06486    415   KC1D_RAT Casein kinase I isoform delta OS=Rat...3294e-92     294     47     62GO:0005813; C:centrosome; TAS:RGD.::GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; ISS:UniProtKB.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0005625; C:soluble fraction; IDA:RGD.::GO:0005819; C:spindle; TAS:RGD.
GO:0005524; F:ATP binding; IDA:RGD.::GO:0001948; F:glycoprotein binding; IDA:RGD.::GO:0042277; F:peptide binding; IDA:RGD.::GO:0051219; F:phosphoprotein binding; IDA:RGD.::GO:0004674; F:protein serine/threonine kinase activity; IDA:RGD.::GO:0050321; F:tau-protein kinase activity; IEA:EC.
GO:0032922; P:circadian regulation of gene expression; ISS:UniProtKB.::GO:0000278; P:mitotic cell cycle; TAS:RGD.::GO:0032436; P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process; ISS:UniProtKB.::GO:0042752; P:regulation of circadian rhythm; ISS:UniProtKB.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
38Q9DC28    415   KC1D_MOUSE Casein kinase I isoform delta OS=M...3294e-92     294     47     62GO:0005829; C:cytosol; TAS:Reactome.::GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0005654; C:nucleoplasm; TAS:Reactome.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0050321; F:tau-protein kinase activity; IEA:EC.
GO:0032922; P:circadian regulation of gene expression; IMP:UniProtKB.::GO:0032436; P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process; IMP:UniProtKB.::GO:0042752; P:regulation of circadian rhythm; IMP:UniProtKB.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
39Q5RC72    415   KC1D_PONAB Casein kinase I isoform delta OS=P...3295e-92     293     47     62GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; ISS:UniProtKB.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0005819; C:spindle; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0050321; F:tau-protein kinase activity; IEA:EC.
GO:0032922; P:circadian regulation of gene expression; ISS:UniProtKB.::GO:0032436; P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process; ISS:UniProtKB.::GO:0042752; P:regulation of circadian rhythm; ISS:UniProtKB.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
40Q7RBX5    323   KC1_PLAYO Casein kinase I OS=Plasmodium yoeli...3195e-92     290     46     63
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
41Q6P647    415   KC1D_XENTR Casein kinase I isoform delta OS=X...3297e-92     293     47     62GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
42P97633    325   KC1A_RAT Casein kinase I isoform alpha OS=Rat...3348e-92     290     46     61GO:0000777; C:condensed chromosome kinetochore; IEA:UniProtKB-SubCell.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.::GO:0016607; C:nuclear speck; ISS:UniProtKB.::GO:0005625; C:soluble fraction; IDA:RGD.
GO:0005524; F:ATP binding; IDA:RGD.::GO:0001948; F:glycoprotein binding; IDA:RGD.::GO:0000287; F:magnesium ion binding; IDA:RGD.::GO:0042277; F:peptide binding; IDA:RGD.::GO:0051219; F:phosphoprotein binding; IDA:RGD.::GO:0004674; F:protein serine/threonine kinase activity; IDA:RGD.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
43Q9JMK2    416   KC1E_MOUSE Casein kinase I isoform epsilon OS...3339e-92     293     47     61GO:0005829; C:cytosol; TAS:Reactome.::GO:0005654; C:nucleoplasm; TAS:Reactome.::GO:0030529; C:ribonucleoprotein complex; IDA:MGI.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0034613; P:cellular protein localization; IDA:MGI.::GO:0007623; P:circadian rhythm; TAS:MGI.::GO:0030178; P:negative regulation of Wnt receptor signaling pathway; IGI:MGI.::GO:0090263; P:positive regulation of canonical Wnt receptor signaling pathway; IGI:MGI.::GO:0032436; P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process; IMP:UniProtKB.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
44Q556Y4    426   KC1_DICDI Casein kinase I OS=Dictyostelium di...3249e-92     293     48     61GO:0005813; C:centrosome; TAS:dictyBase.::GO:0005634; C:nucleus; IDA:dictyBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IDA:dictyBase.
GO:0006281; P:DNA repair; IMP:dictyBase.::GO:0007165; P:signal transduction; ISS:dictyBase.
45P42158    450   KC1D_ARATH Casein kinase I isoform delta-like...3261e-91     293     47     61GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0009506; C:plasmodesma; IDA:TAIR.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
46Q5ZLL1    416   KC1E_CHICK Casein kinase I isoform epsilon OS...3331e-91     292     47     62GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0032436; P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process; ISS:UniProtKB.
47P49674    416   KC1E_HUMAN Casein kinase I isoform epsilon OS...3332e-91     292     47     61GO:0005829; C:cytosol; TAS:Reactome.::GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; TAS:UniProtKB.
GO:0006281; P:DNA repair; TAS:ProtInc.::GO:0000086; P:G2/M transition of mitotic cell cycle; TAS:Reactome.::GO:0032436; P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process; ISS:UniProtKB.::GO:0007165; P:signal transduction; TAS:ProtInc.
48Q6P3K7    409   KC1DB_DANRE Casein kinase I isoform delta-B O...3296e-91     290     47     61GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
49Q7T2E3    403   KC1DA_DANRE Casein kinase I isoform delta-A O...3297e-91     290     47     61GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
50P42168    341   KC1A_CAEEL Casein kinase I isoform alpha OS=C...3271e-90     287     46     60GO:0005813; C:centrosome; IDA:WormBase.::GO:0005634; C:nucleus; IDA:WormBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0006915; P:apoptotic process; IMP:WormBase.::GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0007052; P:mitotic spindle organization; IMP:WormBase.::GO:0000003; P:reproduction; IMP:WormBase.::GO:0060069; P:Wnt receptor signaling pathway, regulating spindle positioning; IMP:WormBase.
51O15726    324   KC1_PLAF4 Casein kinase I OS=Plasmodium falci...3197e-90     285     46     62
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
52Q8N752    337   KC1AL_HUMAN Casein kinase I isoform alpha-lik...3353e-89     284     45     60GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
53P29295    494   HRR25_YEAST Casein kinase I homolog HRR25 OS=...3269e-89     288     47     61GO:0005935; C:cellular bud neck; IDA:SGD.::GO:0005934; C:cellular bud tip; IDA:SGD.::GO:0033551; C:monopolin complex; IDA:SGD.::GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.::GO:0005654; C:nucleoplasm; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IDA:SGD.::GO:0005816; C:spindle pole body; IDA:SGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0042802; F:identical protein binding; IPI:IntAct.::GO:0004674; F:protein serine/threonine kinase activity; IDA:SGD.
GO:0051455; P:attachment of spindle microtubules to kinetochore involved in homologous chromosome segregation; IMP:SGD.::GO:0006281; P:DNA repair; IMP:SGD.::GO:0006888; P:ER to Golgi vesicle-mediated transport; IMP:SGD.::GO:0007067; P:mitosis; IMP:SGD.::GO:0042274; P:ribosomal small subunit biogenesis; IMP:SGD.::GO:0002098; P:tRNA wobble uridine modification; IMP:SGD.
54P35509    276   KC1G3_BOVIN Casein kinase I isoform gamma-3 O...2962e-88     280     50     65GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
55Q20471    497   KIN20_CAEEL Casein kinase I isoform delta OS=...3425e-87     283     47     59GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0010171; P:body morphogenesis; IMP:WormBase.::GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0040011; P:locomotion; IMP:WormBase.::GO:0002119; P:nematode larval development; IMP:WormBase.::GO:0040010; P:positive regulation of growth rate; IMP:WormBase.::GO:0040018; P:positive regulation of multicellular organism growth; IMP:WormBase.::GO:0000003; P:reproduction; IMP:WormBase.::GO:0048511; P:rhythmic process; IEA:UniProtKB-KW.
56P40236    400   HHP2_SCHPO Casein kinase I homolog hhp2 OS=Sc...3262e-86     279     45     60GO:0005739; C:mitochondrion; IDA:PomBase.::GO:0033551; C:monopolin complex; ISS:PomBase.::GO:0005634; C:nucleus; ISS:PomBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; ISS:PomBase.
GO:0051455; P:attachment of spindle microtubules to kinetochore involved in homologous chromosome segregation; ISS:PomBase.::GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0006282; P:regulation of DNA repair; IMP:PomBase.::GO:0007165; P:signal transduction; NAS:PomBase.
57O76324    440   DCO_DROME Discs overgrown protein kinase OS=D...3291e-85     278     45     61GO:0005737; C:cytoplasm; IDA:FlyBase.::GO:0005634; C:nucleus; IDA:FlyBase.::GO:0005886; C:plasma membrane; IDA:FlyBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; NAS:FlyBase.
GO:0048148; P:behavioral response to cocaine; IMP:FlyBase.::GO:0008062; P:eclosion rhythm; TAS:FlyBase.::GO:0001737; P:establishment of imaginal disc-derived wing hair orientation; IMP:FlyBase.::GO:0042067; P:establishment of ommatidial planar polarity; IMP:FlyBase.::GO:0007446; P:imaginal disc growth; IMP:FlyBase.::GO:0045475; P:locomotor rhythm; NAS:FlyBase.::GO:0043066; P:negative regulation of apoptotic process; IMP:FlyBase.::GO:0051781; P:positive regulation of cell division; IMP:FlyBase.::GO:0030307; P:positive regulation of cell growth; IMP:FlyBase.::GO:0042306; P:regulation of protein import into nucleus; TAS:FlyBase.::GO:0030431; P:sleep; NAS:FlyBase.::GO:0016055; P:Wnt receptor signaling pathway; IMP:FlyBase.
58P54367    337   KC1A_DROME Casein kinase I isoform alpha OS=D...3271e-84     272     47     61GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0005634; C:nucleus; IDA:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; NAS:FlyBase.
GO:0000902; P:cell morphogenesis; IMP:FlyBase.::GO:0006281; P:DNA repair; IDA:FlyBase.::GO:0002121; P:inter-male aggressive behavior; IMP:FlyBase.::GO:0045879; P:negative regulation of smoothened signaling pathway; IMP:FlyBase.::GO:0006911; P:phagocytosis, engulfment; IMP:FlyBase.::GO:0030163; P:protein catabolic process; NAS:FlyBase.::GO:0030162; P:regulation of proteolysis; TAS:FlyBase.::GO:0030111; P:regulation of Wnt receptor signaling pathway; IMP:FlyBase.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
59P35507    336   KC1B_BOVIN Casein kinase I isoform beta OS=Bo...3283e-79     258     44     58GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW.
60Q8SS96    304   KC11_ENCCU Probable casein kinase I homolog E...3193e-65     220     38     58GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
61Q54DF7    495   Y2354_DICDI Probable serine/threonine-protein...3256e-44     167     31     52
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; ISS:dictyBase.
GO:0006281; P:DNA repair; ISS:dictyBase.::GO:0007165; P:signal transduction; ISS:dictyBase.
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