Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YER123W
Length:
524
Number of sequences:
5887
Description:
YER123W YCK3 SGDID:S000000925, Chr V from 404813-406387, Genome Release 64-1-1, Verified ORF, "Palmitoylated, vacuolar membrane-localized casein kinase I isoform; negatively regulates vacuole fusion during hypertonic stress via phosphorylation of Vps41p; shares essential functions with Hrr25p; regulates vesicle fusion in AP-3 pathway"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
181P54744    622   PKNB_MYCLE Serine/threonine-protein kinase pk...1140.00008     48.9     27     44
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0008658; F:penicillin binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
182Q07785    288   CDC2H_PLAFK Cell division control protein 2 h...2590.00008     48.1     22     41GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IEA:EC.
183P61075    288   CDC2H_PLAF7 Cell division control protein 2 h...2590.00008     48.1     22     41GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; ISS:GeneDB_Pfalciparum.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IEA:EC.
184Q7T6Y1    276   YR436_MIMIV Putative serine/threonine-protein...1390.00008     48.1     24     47
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
185O61122    478   SVKA_DICDI Serine/threonine-protein kinase sv...2370.00009     48.5     24     40GO:0030479; C:actin cortical patch; IEA:UniProtKB-SubCell.::GO:0005813; C:centrosome; IDA:dictyBase.::GO:0032154; C:cleavage furrow; IDA:dictyBase.
GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IMP:UniProtKB.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0006972; P:hyperosmotic response; IEP:dictyBase.::GO:0051781; P:positive regulation of cell division; IMP:UniProtKB.::GO:0046777; P:protein autophosphorylation; IDA:dictyBase.::GO:0032956; P:regulation of actin cytoskeleton organization; IMP:UniProtKB.::GO:0010590; P:regulation of cytokinetic cell separation; IMP:dictyBase.::GO:0031156; P:regulation of sorocarp development; IMP:dictyBase.::GO:0007165; P:signal transduction; ISS:dictyBase.
186Q9XA16    673   PKNX_STRCO Probable serine/threonine-protein ...2510.00009     48.9     22     41
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008658; F:penicillin binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
187Q12236    1081   PKH2_YEAST Serine/threonine-protein kinase PK...1740.00009     48.9     26     39GO:0032126; C:eisosome; IDA:SGD.::GO:0005634; C:nucleus; IDA:SGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0033962; P:cytoplasmic mRNA processing body assembly; IGI:SGD.::GO:0006897; P:endocytosis; IEA:UniProtKB-KW.::GO:0000196; P:MAPK cascade involved in cell wall biogenesis; IGI:SGD.::GO:0060211; P:regulation of nuclear-transcribed mRNA poly(A) tail shortening; IGI:SGD.
188P53681    602   CRK_DAUCA CDPK-related protein kinase OS=Dauc...2510.0001     48.9     23     40
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
189P33981    857   TTK_HUMAN Dual specificity protein kinase TTK...1570.0001     48.9     25     40GO:0005819; C:spindle; TAS:ProtInc.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; TAS:ProtInc.::GO:0004712; F:protein serine/threonine/tyrosine kinase activity; IEA:EC.::GO:0004713; F:protein tyrosine kinase activity; TAS:ProtInc.
GO:0007094; P:mitotic cell cycle spindle assembly checkpoint; TAS:ProtInc.::GO:0007052; P:mitotic spindle organization; TAS:ProtInc.::GO:0008284; P:positive regulation of cell proliferation; TAS:ProtInc.::GO:0010862; P:positive regulation of pathway-restricted SMAD protein phosphorylation; TAS:BHF-UCL.
190P11730    527   KCC2G_RAT Calcium/calmodulin-dependent protei...2420.0001     48.5     21     41GO:0005954; C:calcium- and calmodulin-dependent protein kinase complex; TAS:UniProtKB.::GO:0033017; C:sarcoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005516; F:calmodulin binding; IEA:UniProtKB-KW.::GO:0004683; F:calmodulin-dependent protein kinase activity; IDA:RGD.
GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0007399; P:nervous system development; IEA:UniProtKB-KW.::GO:0046777; P:protein autophosphorylation; IDA:RGD.::GO:0048169; P:regulation of long-term neuronal synaptic plasticity; TAS:RGD.::GO:0001666; P:response to hypoxia; IDA:RGD.::GO:0006979; P:response to oxidative stress; IDA:RGD.
191P22216    821   RAD53_YEAST Serine/threonine-protein kinase R...1530.0001     48.9     25     44GO:0005634; C:nucleus; IDA:SGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003688; F:DNA replication origin binding; IDA:SGD.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0004712; F:protein serine/threonine/tyrosine kinase activity; IDA:SGD.::GO:0004713; F:protein tyrosine kinase activity; IEA:UniProtKB-KW.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0009202; P:deoxyribonucleoside triphosphate biosynthetic process; IMP:SGD.::GO:0006281; P:DNA repair; IMP:SGD.::GO:0006270; P:DNA-dependent DNA replication initiation; IMP:SGD.::GO:0008104; P:protein localization; IMP:SGD.
192O34507    648   PRKC_BACSU Serine/threonine-protein kinase Pr...1410.0001     48.5     25     41GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IDA:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008658; F:penicillin binding; IEA:InterPro.::GO:0042834; F:peptidoglycan binding; IDA:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
GO:0071224; P:cellular response to peptidoglycan; IMP:UniProtKB.::GO:0007165; P:signal transduction; IMP:UniProtKB.::GO:0009847; P:spore germination; IMP:UniProtKB.
193O96821    288   CDC2H_PLAKH Cell division control protein 2 h...2590.0001     47.8     22     41GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.::GO:0008353; F:RNA polymerase II carboxy-terminal domain kinase activity; IEA:EC.
194Q8IYT8    1036   ULK2_HUMAN Serine/threonine-protein kinase UL...2560.0001     48.5     23     38GO:0030659; C:cytoplasmic vesicle membrane; IEA:UniProtKB-SubCell.::GO:0034045; C:pre-autophagosomal structure membrane; IDA:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004674; F:protein serine/threonine kinase activity; IDA:UniProtKB.
GO:0006914; P:autophagy; IEA:UniProtKB-KW.::GO:0007409; P:axonogenesis; IEA:InterPro.::GO:0046777; P:protein autophosphorylation; IDA:UniProtKB.::GO:0010506; P:regulation of autophagy; IDA:UniProtKB.::GO:0042594; P:response to starvation; ISS:UniProtKB.::GO:0007165; P:signal transduction; IEA:InterPro.
195Q15349    733   KS6A2_HUMAN Ribosomal protein S6 kinase alpha...1670.0001     48.5     28     43GO:0005829; C:cytosol; TAS:Reactome.::GO:0005654; C:nucleoplasm; TAS:Reactome.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; TAS:ProtInc.
GO:0007411; P:axon guidance; TAS:Reactome.::GO:0045087; P:innate immune response; TAS:Reactome.::GO:0002755; P:MyD88-dependent toll-like receptor signaling pathway; TAS:Reactome.::GO:0045786; P:negative regulation of cell cycle; IDA:UniProtKB.::GO:0008285; P:negative regulation of cell proliferation; IDA:UniProtKB.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0043065; P:positive regulation of apoptotic process; IDA:UniProtKB.::GO:0051403; P:stress-activated MAPK cascade; TAS:Reactome.::GO:0007268; P:synaptic transmission; TAS:Reactome.::GO:0008063; P:Toll signaling pathway; TAS:Reactome.::GO:0034130; P:toll-like receptor 1 signaling pathway; TAS:Reactome.::GO:0034134; P:toll-like receptor 2 signaling pathway; TAS:Reactome.::GO:0034138; P:toll-like receptor 3 signaling pathway; TAS:Reactome.::GO:0034142; P:toll-like receptor 4 signaling pathway; TAS:Reactome.::GO:0035666; P:TRIF-dependent toll-like receptor signaling pathway; TAS:Reactome.
196Q01389    1478   BCK1_YEAST Serine/threonine-protein kinase BC...2790.0001     48.9     21     40GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0043332; C:mating projection tip; IDA:SGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004709; F:MAP kinase kinase kinase activity; IGI:SGD.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004713; F:protein tyrosine kinase activity; IEA:UniProtKB-KW.
GO:0030968; P:endoplasmic reticulum unfolded protein response; IMP:SGD.::GO:0030010; P:establishment of cell polarity; IMP:SGD.::GO:0030242; P:peroxisome degradation; IMP:SGD.::GO:0001101; P:response to acid; IMP:SGD.::GO:0007584; P:response to nutrient; IMP:SGD.
197Q5SUV5    386   MYLK4_MOUSE Myosin light chain kinase family ...2530.0001     48.1     25     42
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
198Q4R945    856   TTK_MACFA Dual specificity protein kinase TTK...1550.0001     48.5     26     40
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0004712; F:protein serine/threonine/tyrosine kinase activity; IEA:EC.::GO:0004713; F:protein tyrosine kinase activity; IEA:UniProtKB-KW.
199P0A5S4    626   PKNB_MYCTU Serine/threonine-protein kinase pk...1140.0001     48.5     27     43
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0030145; F:manganese ion binding; IDA:MTBBASE.::GO:0008658; F:penicillin binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:MTBBASE.::GO:0004674; F:protein serine/threonine kinase activity; IDA:MTBBASE.
GO:0040007; P:growth; IMP:MTBBASE.::GO:0043086; P:negative regulation of catalytic activity; IDA:MTBBASE.::GO:0032091; P:negative regulation of protein binding; IDA:MTBBASE.::GO:0043085; P:positive regulation of catalytic activity; IDA:MTBBASE.::GO:0043388; P:positive regulation of DNA binding; IDA:MTBBASE.::GO:0046777; P:protein autophosphorylation; IDA:MTBBASE.::GO:0008360; P:regulation of cell shape; IMP:MTBBASE.::GO:0051338; P:regulation of transferase activity; IDA:MTBBASE.::GO:0052572; P:response to host immune response; IDA:MTBBASE.
200P0A5S5    626   PKNB_MYCBO Serine/threonine-protein kinase pk...1140.0001     48.5     27     43
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0008658; F:penicillin binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
201Q54MH0    749   FHKD_DICDI Probable serine/threonine-protein ...1900.0001     48.5     26     42
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0000077; P:DNA damage checkpoint; ISS:dictyBase.
202Q5F3L1    789   KS6A5_CHICK Ribosomal protein S6 kinase alpha...2490.0001     48.5     24     41GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
203Q61RA2    493   CHK1_CAEBR Serine/threonine-protein kinase ch...1290.0001     48.1     26     44GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.::GO:0006974; P:response to DNA damage stimulus; IEA:UniProtKB-KW.
204Q42438    533   CDPK8_ARATH Calcium-dependent protein kinase ...2570.0002     48.1     20     42GO:0005886; C:plasma membrane; IDA:TAIR.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
205Q63562    467   M3K8_RAT Mitogen-activated protein kinase kin...1480.0002     47.8     26     41GO:0005829; C:cytosol; TAS:Reactome.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0004709; F:MAP kinase kinase kinase activity; IEA:EC.
GO:0007049; P:cell cycle; IEA:InterPro.
206Q8SR90    309   Y8H9_ENCCU Probable cell division protein kin...2740.0002     47.4     23     40GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004693; F:cyclin-dependent protein kinase activity; IEA:EC.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.
207Q8NU98    646   PKN1_CORGL Probable serine/threonine-protein ...1200.0002     48.1     23     46
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008658; F:penicillin binding; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
208Q86AD7    392   MYLKB_DICDI Probable myosin light chain kinas...2450.0002     47.4     21     40
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004687; F:myosin light chain kinase activity; IEA:EC.
GO:0007165; P:signal transduction; ISS:dictyBase.
209Q9UBS0    482   KS6B2_HUMAN Ribosomal protein S6 kinase beta-...1900.0002     47.4     27     39GO:0005654; C:nucleoplasm; TAS:Reactome.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.::GO:0008543; P:fibroblast growth factor receptor signaling pathway; TAS:Reactome.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0048015; P:phosphatidylinositol-mediated signaling; TAS:Reactome.::GO:0045948; P:positive regulation of translational initiation; IMP:UniProtKB.::GO:0006412; P:translation; TAS:ProtInc.
210Q9N0X0    344   AURKB_PIG Aurora kinase B OS=Sus scrofa (Pig)...1580.0002     47     25     43GO:0000775; C:chromosome, centromeric region; IEA:UniProtKB-SubCell.::GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005819; C:spindle; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0071777; P:positive regulation of cell cycle cytokinesis; ISS:UniProtKB.::GO:0034501; P:protein localization to kinetochore; ISS:UniProtKB.::GO:0051256; P:spindle midzone assembly involved in mitosis; ISS:UniProtKB.
211Q4P5N0    746   STE20_USTMA Serine/threonine-protein kinase S...2390.0002     47.8     23     41GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
GO:0019236; P:response to pheromone; IEA:UniProtKB-KW.
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