Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YER122C
Length:
493
Number of sequences:
5887
Description:
YER122C GLO3 SGDID:S000000924, Chr V from 404352-402871, Genome Release 64-1-1, reverse complement, Verified ORF, "ADP-ribosylation factor GTPase activating protein (ARF GAP), involved in ER-Golgi transport; shares functional similarity with Gcs1p"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
61Q9SMX5    775   AGD4_ARATH ADP-ribosylation factor GTPase-act...640.00000000004     69.3     48     61GO:0005737; C:cytoplasm; IEA:InterPro.
GO:0008060; F:ARF GTPase activator activity; IEA:InterPro.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro.
62A5PK26    745   ACAP1_BOVIN Arf-GAP with coiled-coil, ANK rep...490.00000000004     69.3     53     65
GO:0008060; F:ARF GTPase activator activity; IEA:InterPro.::GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro.
63Q96P47    875   AGAP3_HUMAN Arf-GAP with GTPase, ANK repeat a...690.0000000002     67.4     38     54GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:InterPro.
GO:0008060; F:ARF GTPase activator activity; IEA:InterPro.::GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0003924; F:GTPase activity; IEA:InterPro.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
64Q8TF27    550   AGA11_HUMAN Arf-GAP with GTPase, ANK repeat a...860.0000000002     67     33     52
GO:0008060; F:ARF GTPase activator activity; IEA:InterPro.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro.
65Q6NRL1    864   AGAP1_XENLA Arf-GAP with GTPase, ANK repeat a...860.0000000002     67     33     51GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0008060; F:ARF GTPase activator activity; IEA:InterPro.::GO:0005525; F:GTP binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro.
66Q5VUJ5    663   AGAP7_HUMAN Arf-GAP with GTPase, ANK repeat a...860.0000000002     66.6     33     52
GO:0008060; F:ARF GTPase activator activity; IEA:InterPro.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro.
67Q96P64    663   AGAP4_HUMAN Arf-GAP with GTPase, ANK repeat a...860.0000000002     66.6     33     52
GO:0008060; F:ARF GTPase activator activity; IEA:InterPro.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro.
68Q8WWN8    1544   ARAP3_HUMAN Arf-GAP with Rho-GAP domain, ANK ...1190.0000000004     66.2     33     55GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0030027; C:lamellipodium; ISS:UniProtKB.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0001726; C:ruffle; ISS:UniProtKB.
GO:0008060; F:ARF GTPase activator activity; ISS:UniProtKB.::GO:0005547; F:phosphatidylinositol-3,4,5-trisphosphate binding; IDA:UniProtKB.::GO:0043325; F:phosphatidylinositol-3,4-bisphosphate binding; IDA:UniProtKB.::GO:0005100; F:Rho GTPase activator activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007010; P:cytoskeleton organization; TAS:UniProtKB.::GO:0030336; P:negative regulation of cell migration; ISS:UniProtKB.::GO:0035024; P:negative regulation of Rho protein signal transduction; ISS:UniProtKB.::GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro.::GO:0008360; P:regulation of cell shape; ISS:UniProtKB.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.::GO:0016192; P:vesicle-mediated transport; TAS:UniProtKB.
69Q5T2P9    658   AGA10_HUMAN Arf-GAP with GTPase, ANK repeat a...840.0000000006     65.1     32     51
GO:0008060; F:ARF GTPase activator activity; IEA:InterPro.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro.
70Q4LDD4    1452   ARAP1_MOUSE Arf-GAP with Rho-GAP domain, ANK ...1290.0000000008     65.5     28     49GO:0032580; C:Golgi cisterna membrane; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0070412; F:R-SMAD binding; ISS:BHF-UCL.::GO:0005100; F:Rho GTPase activator activity; ISS:UniProtKB.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; ISS:UniProtKB.::GO:0008134; F:transcription factor binding; ISS:BHF-UCL.::GO:0044212; F:transcription regulatory region DNA binding; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0045893; P:positive regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro.::GO:0007184; P:SMAD protein import into nucleus; ISS:UniProtKB.::GO:0060395; P:SMAD protein signal transduction; ISS:UniProtKB.::GO:0007179; P:transforming growth factor beta receptor signaling pathway; ISS:UniProtKB.
71Q5VTM2    703   AGAP9_HUMAN Arf-GAP with GTPase, ANK repeat a...840.000000001     64.7     32     51
GO:0008060; F:ARF GTPase activator activity; IEA:InterPro.::GO:0005525; F:GTP binding; IEA:InterPro.::GO:0003924; F:GTPase activity; IEA:InterPro.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro.
72Q8TDY4    903   ASAP3_HUMAN Arf-GAP with SH3 domain, ANK repe...600.000000001     64.7     45     62GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0008060; F:ARF GTPase activator activity; IEA:InterPro.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro.
73Q5SRD3    663   AGAP8_HUMAN Arf-GAP with GTPase, ANK repeat a...860.000000001     64.3     31     51
GO:0008060; F:ARF GTPase activator activity; IEA:InterPro.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro.
74Q5U464    904   ASAP3_MOUSE Arf-GAP with SH3 domain, ANK repe...600.000000002     63.9     45     60GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0008060; F:ARF GTPase activator activity; IEA:InterPro.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro.
75A8MT82    671   CTLFB_HUMAN Putative centaurin-gamma-like fam...860.000000003     62.8     31     51
GO:0008060; F:ARF GTPase activator activity; IEA:InterPro.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro.
76P40529    298   AGE2_YEAST ADP-ribosylation factor GTPase-act...900.000000007     60.5     31     51GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.
GO:0008060; F:ARF GTPase activator activity; IDA:SGD.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006888; P:ER to Golgi vesicle-mediated transport; IGI:SGD.::GO:0006891; P:intra-Golgi vesicle-mediated transport; IGI:SGD.::GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro.
77A6NIR3    686   AGAP5_HUMAN Arf-GAP with GTPase, ANK repeat a...860.000000009     61.6     31     51
GO:0008060; F:ARF GTPase activator activity; IEA:InterPro.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro.
78Q96P48    1450   ARAP1_HUMAN Arf-GAP with Rho-GAP domain, ANK ...940.00000002     61.2     30     50GO:0005829; C:cytosol; TAS:Reactome.::GO:0032580; C:Golgi cisterna membrane; IEA:UniProtKB-SubCell.::GO:0005622; C:intracellular; IEA:InterPro.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0008060; F:ARF GTPase activator activity; IDA:UniProtKB.::GO:0005547; F:phosphatidylinositol-3,4,5-trisphosphate binding; IDA:UniProtKB.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0005100; F:Rho GTPase activator activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0030037; P:actin filament reorganization involved in cell cycle; TAS:UniProtKB.::GO:0051497; P:negative regulation of stress fiber assembly; IMP:UniProtKB.::GO:0043089; P:positive regulation of Cdc42 GTPase activity; IDA:UniProtKB.::GO:0051491; P:positive regulation of filopodium assembly; IMP:UniProtKB.::GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro.::GO:0008360; P:regulation of cell shape; IMP:UniProtKB.::GO:0051270; P:regulation of cellular component movement; IMP:UniProtKB.::GO:0007165; P:signal transduction; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.
79Q10165    923   CNT6_SCHPO Probable ribosylation factor GTPas...520.00000002     60.8     46     71GO:0032153; C:cell division site; IDA:PomBase.::GO:0051286; C:cell tip; IDA:PomBase.::GO:0005829; C:cytosol; IDA:PomBase.
GO:0008060; F:ARF GTPase activator activity; IEA:InterPro.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006886; P:intracellular protein transport; NAS:PomBase.::GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; NAS:PomBase.
80Q68FF6    770   GIT1_MOUSE ARF GTPase-activating protein GIT1...970.00000002     60.5     30     49GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro.
81Q9Z272    770   GIT1_RAT ARF GTPase-activating protein GIT1 O...970.00000002     60.5     30     49GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005925; C:focal adhesion; TAS:RGD.
GO:0008060; F:ARF GTPase activator activity; IDA:RGD.::GO:0042803; F:protein homodimerization activity; IDA:RGD.::GO:0031267; F:small GTPase binding; IDA:RGD.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro.::GO:0008277; P:regulation of G-protein coupled receptor protein signaling pathway; IDA:RGD.
82Q9Y2X7    761   GIT1_HUMAN ARF GTPase-activating protein GIT1...970.00000002     60.5     30     49GO:0005737; C:cytoplasm; IDA:HPA.::GO:0005925; C:focal adhesion; IDA:HPA.
GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro.::GO:0008277; P:regulation of G-protein coupled receptor protein signaling pathway; TAS:ProtInc.
83Q8WZ64    1704   ARAP2_HUMAN Arf-GAP with Rho-GAP domain, ANK ...1190.00000003     60.1     29     50GO:0005829; C:cytosol; TAS:Reactome.
GO:0008060; F:ARF GTPase activator activity; IEA:InterPro.::GO:0005547; F:phosphatidylinositol-3,4,5-trisphosphate binding; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.
84Q8BZ05    1703   ARAP2_MOUSE Arf-GAP with Rho-GAP domain, ANK ...1090.00000003     60.1     31     50GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0008060; F:ARF GTPase activator activity; IEA:InterPro.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro.::GO:0007165; P:signal transduction; IEA:InterPro.
85Q8R5G7    1538   ARAP3_MOUSE Arf-GAP with Rho-GAP domain, ANK ...820.00000004     60.1     38     57GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0030027; C:lamellipodium; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0001726; C:ruffle; IEA:UniProtKB-SubCell.
GO:0008060; F:ARF GTPase activator activity; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0005100; F:Rho GTPase activator activity; IDA:MGI.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0030336; P:negative regulation of cell migration; IDA:MGI.::GO:0035021; P:negative regulation of Rac protein signal transduction; IDA:MGI.::GO:0035024; P:negative regulation of Rho protein signal transduction; IDA:MGI.::GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro.::GO:0008360; P:regulation of cell shape; IDA:MGI.::GO:0007165; P:signal transduction; IEA:InterPro.
86Q8RXE7    649   AGD14_ARATH Probable ADP-ribosylation factor ...880.00000006     58.9     31     52GO:0005886; C:plasma membrane; IDA:TAIR.
GO:0008060; F:ARF GTPase activator activity; IEA:InterPro.::GO:0004674; F:protein serine/threonine kinase activity; IDA:TAIR.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0046777; P:protein autophosphorylation; IDA:TAIR.::GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro.
87O75689    374   ADAP1_HUMAN Arf-GAP with dual PH domain-conta...840.0000002     57     35     49GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0005634; C:nucleus; IDA:UniProtKB.::GO:0005886; C:plasma membrane; IDA:UniProtKB.
GO:0008060; F:ARF GTPase activator activity; IDA:UniProtKB.::GO:0043533; F:inositol 1,3,4,5 tetrakisphosphate binding; TAS:UniProtKB.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007166; P:cell surface receptor signaling pathway; TAS:ProtInc.::GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro.
88Q9UUE2    870   CSX2_SCHPO Protein csx2 OS=Schizosaccharomyce...600.0000002     57.4     40     57GO:0005829; C:cytosol; IDA:PomBase.::GO:0005886; C:plasma membrane; IDA:PomBase.
GO:0008060; F:ARF GTPase activator activity; IEA:InterPro.::GO:0005543; F:phospholipid binding; IDA:PomBase.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0071276; P:cellular response to cadmium ion; IMP:PomBase.::GO:0006886; P:intracellular protein transport; NAS:PomBase.::GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro.::GO:0046685; P:response to arsenic-containing substance; IMP:PomBase.::GO:0007264; P:small GTPase mediated signal transduction; IC:PomBase.
89P40956    396   GTS1_YEAST Protein GTS1 OS=Saccharomyces cere...650.0000004     55.8     43     60GO:0030479; C:actin cortical patch; IDA:SGD.::GO:0005634; C:nucleus; IDA:SGD.
GO:0008060; F:ARF GTPase activator activity; IMP:SGD.::GO:0070491; F:repressing transcription factor binding; IPI:SGD.::GO:0000989; F:transcription factor binding transcription factor activity; IMP:SGD.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006897; P:endocytosis; IMP:SGD.::GO:0010512; P:negative regulation of phosphatidylinositol biosynthetic process; IMP:SGD.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IMP:SGD.::GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0007624; P:ultradian rhythm; IMP:SGD.
90Q14161    759   GIT2_HUMAN ARF GTPase-activating protein GIT2...1010.0000005     56.2     30     50GO:0005654; C:nucleoplasm; IDA:UniProtKB.
GO:0008060; F:ARF GTPase activator activity; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro.::GO:0008277; P:regulation of G-protein coupled receptor protein signaling pathway; TAS:ProtInc.
91Q04412    482   AGE1_YEAST ADP-ribosylation factor GTPase-act...510.000001     54.7     45     65GO:0005768; C:endosome; IDA:SGD.::GO:0005802; C:trans-Golgi network; IDA:SGD.
GO:0008060; F:ARF GTPase activator activity; IDA:SGD.::GO:0005543; F:phospholipid binding; IDA:SGD.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006888; P:ER to Golgi vesicle-mediated transport; IGI:SGD.::GO:0006891; P:intra-Golgi vesicle-mediated transport; IGI:SGD.::GO:0015031; P:protein transport; IEA:UniProtKB-KW.::GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro.
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