Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YER120W
Length:
244
Number of sequences:
5887
Description:
YER120W SCS2 SGDID:S000000922, Chr V from 401135-401869, Genome Release 64-1-1, Verified ORF, "Integral ER membrane protein that regulates phospholipid metabolism via an interaction with the FFAT motif of Opi1p, also involved in telomeric silencing, disruption causes inositol auxotrophy above 34 degrees C, VAP homolog"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
1P40075    244   SCS2_YEAST Vesicle-associated membrane protei...2444e-175     488     100     100GO:0005934; C:cellular bud tip; IDA:SGD.::GO:0030176; C:integral to endoplasmic reticulum membrane; IDA:SGD.::GO:0031965; C:nuclear membrane; IDA:SGD.
GO:0033149; F:FFAT motif binding; IMP:SGD.::GO:0035091; F:phosphatidylinositol binding; IDA:SGD.::GO:0005198; F:structural molecule activity; IEA:InterPro.
GO:0006348; P:chromatin silencing at telomere; IMP:SGD.::GO:0048309; P:endoplasmic reticulum inheritance; IMP:SGD.::GO:0042992; P:negative regulation of transcription factor import into nucleus; IMP:SGD.::GO:0008654; P:phospholipid biosynthetic process; IMP:SGD.::GO:0032377; P:regulation of intracellular lipid transport; IMP:SGD.
2Q6Q595    175   SCS22_YEAST Vesicle-associated membrane prote...1411e-29     114     40     65GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0005198; F:structural molecule activity; IEA:InterPro.
GO:0008654; P:phospholipid biosynthetic process; IGI:SGD.
3O60119    383   YH75_SCHPO Vesicle-associated membrane protei...2365e-21     94     31     47GO:0030176; C:integral to endoplasmic reticulum membrane; ISS:PomBase.
GO:0005198; F:structural molecule activity; IEA:InterPro.
GO:0006020; P:inositol metabolic process; ISS:PomBase.::GO:0008654; P:phospholipid biosynthetic process; ISS:PomBase.
4Q10484    319   YDFC_SCHPO Uncharacterized protein C17C9.12 O...1235e-17     81.6     37     50GO:0005829; C:cytosol; IDA:PomBase.::GO:0030176; C:integral to endoplasmic reticulum membrane; ISS:PomBase.
GO:0005198; F:structural molecule activity; IEA:InterPro.
GO:0006020; P:inositol metabolic process; ISS:PomBase.::GO:0008654; P:phospholipid biosynthetic process; ISS:PomBase.
5B9DHD7    386   VAP22_ARATH Vesicle-associated protein 2-2 OS...870.00000000000003     74.7     43     60GO:0005789; C:endoplasmic reticulum membrane; IDA:TAIR.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IDA:TAIR.
GO:0005198; F:structural molecule activity; IEA:InterPro.
GO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW.::GO:0046907; P:intracellular transport; TAS:TAIR.
6Q0VCY1    249   VAPA_BOVIN Vesicle-associated membrane protei...1070.0000000000001     71.2     37     57GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0005198; F:structural molecule activity; IEA:InterPro.
GO:0008219; P:cell death; ISS:UniProtKB.::GO:0031175; P:neuron projection development; ISS:UniProtKB.::GO:0070972; P:protein localization in endoplasmic reticulum; ISS:UniProtKB.
7Q5R601    249   VAPA_PONAB Vesicle-associated membrane protei...1070.0000000000001     70.9     37     56GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0005198; F:structural molecule activity; IEA:InterPro.
GO:0008219; P:cell death; ISS:UniProtKB.::GO:0031175; P:neuron projection development; ISS:UniProtKB.::GO:0070972; P:protein localization in endoplasmic reticulum; ISS:UniProtKB.
8Q9P0L0    249   VAPA_HUMAN Vesicle-associated membrane protei...1070.0000000000001     70.9     37     56GO:0005789; C:endoplasmic reticulum membrane; TAS:Reactome.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IDA:UniProtKB.::GO:0031982; C:vesicle; IDA:UniProtKB.
GO:0046982; F:protein heterodimerization activity; IPI:UniProtKB.::GO:0004871; F:signal transducer activity; IMP:UniProtKB.::GO:0005198; F:structural molecule activity; IEA:InterPro.
GO:0008219; P:cell death; IMP:UniProtKB.::GO:0006944; P:cellular membrane fusion; TAS:ProtInc.::GO:0031175; P:neuron projection development; IMP:UniProtKB.::GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB cascade; IMP:UniProtKB.::GO:0070972; P:protein localization in endoplasmic reticulum; IMP:UniProtKB.::GO:0044281; P:small molecule metabolic process; TAS:Reactome.::GO:0030148; P:sphingolipid biosynthetic process; TAS:Reactome.
9A5GFS8    243   VAPB_PIG Vesicle-associated membrane protein-...2460.0000000000002     70.9     28     47GO:0005789; C:endoplasmic reticulum membrane; ISS:UniProtKB.::GO:0005794; C:Golgi apparatus; ISS:UniProtKB.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0048487; F:beta-tubulin binding; ISS:UniProtKB.::GO:0019899; F:enzyme binding; ISS:UniProtKB.::GO:0046982; F:protein heterodimerization activity; ISS:UniProtKB.::GO:0042803; F:protein homodimerization activity; ISS:UniProtKB.::GO:0005198; F:structural molecule activity; IEA:InterPro.
GO:0030968; P:endoplasmic reticulum unfolded protein response; ISS:UniProtKB.::GO:0045070; P:positive regulation of viral genome replication; ISS:UniProtKB.::GO:0019048; P:virus-host interaction; ISS:UniProtKB.
10Q9Z270    249   VAPA_RAT Vesicle-associated membrane protein-...1070.0000000000002     70.5     37     56GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005624; C:membrane fraction; IDA:HGNC.
GO:0046982; F:protein heterodimerization activity; IDA:RGD.::GO:0005198; F:structural molecule activity; IEA:InterPro.
GO:0008219; P:cell death; IMP:UniProtKB.::GO:0031175; P:neuron projection development; IMP:UniProtKB.::GO:0070972; P:protein localization in endoplasmic reticulum; ISS:UniProtKB.
11Q84WW5    239   VAP13_ARATH Vesicle-associated protein 1-3 OS...880.0000000000002     70.5     44     59GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0005198; F:structural molecule activity; IEA:InterPro.
12Q9WV55    249   VAPA_MOUSE Vesicle-associated membrane protei...1070.0000000000003     70.1     36     56GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005874; C:microtubule; IDA:MGI.
GO:0005198; F:structural molecule activity; IEA:InterPro.
GO:0008219; P:cell death; ISS:UniProtKB.::GO:0031175; P:neuron projection development; ISS:UniProtKB.::GO:0070972; P:protein localization in endoplasmic reticulum; ISS:UniProtKB.
13A2VDZ9    243   VAPB_BOVIN Vesicle-associated membrane protei...2460.000000000002     67.8     27     46GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0005198; F:structural molecule activity; IEA:InterPro.
14O95292    243   VAPB_HUMAN Vesicle-associated membrane protei...1040.000000000002     67.8     35     57GO:0005789; C:endoplasmic reticulum membrane; IDA:UniProtKB.::GO:0005794; C:Golgi apparatus; IDA:UniProtKB.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0048487; F:beta-tubulin binding; IDA:UniProtKB.::GO:0019899; F:enzyme binding; IPI:UniProtKB.::GO:0046982; F:protein heterodimerization activity; IPI:UniProtKB.::GO:0042803; F:protein homodimerization activity; IPI:UniProtKB.::GO:0005198; F:structural molecule activity; IEA:InterPro.
GO:0008219; P:cell death; IEA:UniProtKB-KW.::GO:0030968; P:endoplasmic reticulum unfolded protein response; IMP:UniProtKB.::GO:0045070; P:positive regulation of viral genome replication; IMP:UniProtKB.::GO:0044281; P:small molecule metabolic process; TAS:Reactome.::GO:0030148; P:sphingolipid biosynthetic process; TAS:Reactome.::GO:0019048; P:virus-host interaction; IDA:UniProtKB.
15Q8VZ95    256   VAP11_ARATH Vesicle-associated protein 1-1 OS...610.000000000005     67     51     66GO:0005829; C:cytosol; IDA:TAIR.::GO:0005789; C:endoplasmic reticulum membrane; IDA:TAIR.::GO:0016021; C:integral to membrane; IDA:TAIR.::GO:0005634; C:nucleus; IDA:TAIR.::GO:0005886; C:plasma membrane; IDA:TAIR.::GO:0000326; C:protein storage vacuole; IDA:TAIR.::GO:0032586; C:protein storage vacuole membrane; IEA:UniProtKB-SubCell.
GO:0005515; F:protein binding; IPI:IntAct.::GO:0005198; F:structural molecule activity; IEA:InterPro.
GO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW.::GO:0046907; P:intracellular transport; TAS:TAIR.
16Q9Z269    243   VAPB_RAT Vesicle-associated membrane protein-...1040.000000000006     66.6     35     57GO:0005789; C:endoplasmic reticulum membrane; ISS:UniProtKB.::GO:0005794; C:Golgi apparatus; ISS:UniProtKB.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0048487; F:beta-tubulin binding; ISS:UniProtKB.::GO:0019899; F:enzyme binding; ISS:UniProtKB.::GO:0042803; F:protein homodimerization activity; ISS:UniProtKB.::GO:0005198; F:structural molecule activity; IEA:InterPro.
GO:0030968; P:endoplasmic reticulum unfolded protein response; ISS:UniProtKB.::GO:0045070; P:positive regulation of viral genome replication; ISS:UniProtKB.::GO:0019048; P:virus-host interaction; ISS:UniProtKB.
17Q9SHC8    239   VAP12_ARATH Vesicle-associated protein 1-2 OS...1290.00000000001     65.9     36     52GO:0005829; C:cytosol; IDA:TAIR.::GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005634; C:nucleus; IDA:TAIR.::GO:0005886; C:plasma membrane; IDA:TAIR.
GO:0005515; F:protein binding; IPI:IntAct.::GO:0005198; F:structural molecule activity; IEA:InterPro.
GO:0006605; P:protein targeting; IDA:UniProtKB.
18Q16943    260   VP33_APLCA Vesicle-associated membrane protei...830.00000000001     65.9     41     61GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0045202; C:synapse; IEA:UniProtKB-KW.::GO:0019717; C:synaptosome; IEA:UniProtKB-SubCell.
GO:0005198; F:structural molecule activity; IEA:InterPro.
19Q9QY76    243   VAPB_MOUSE Vesicle-associated membrane protei...1040.00000000003     64.7     34     56GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005624; C:membrane fraction; IDA:HGNC.
GO:0005198; F:structural molecule activity; IEA:InterPro.
20Q9LVU1    220   VAP21_ARATH Vesicle-associated protein 2-1 OS...840.00000000009     62.8     39     60GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IDA:TAIR.
GO:0005198; F:structural molecule activity; IEA:InterPro.
21Q9SYC9    571   VAP14_ARATH Vesicle-associated protein 1-4 OS...610.00000004     57     48     62GO:0005622; C:intracellular; IEA:InterPro.
GO:0005198; F:structural molecule activity; IEA:InterPro.
GO:0007165; P:signal transduction; IEA:InterPro.
22O82213    149   VAP31_ARATH Vesicle-associated protein 3-1 OS...1270.00000005     53.9     31     52
GO:0005198; F:structural molecule activity; IEA:InterPro.
23Q8VYN2    295   VAP42_ARATH Vesicle-associated protein 4-2 OS...680.00008     46.6     40     57GO:0005886; C:plasma membrane; IDA:TAIR.
GO:0005198; F:structural molecule activity; IEA:InterPro.
24Q8LPQ7    287   VAP43_ARATH Vesicle-associated protein 4-3 OS...360.007     40.4     50     64
GO:0005198; F:structural molecule activity; IEA:InterPro.
25P53023    126   MSP3_GLORO Major sperm protein 3 OS=Globodera...560.009     38.5     32     52GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0031143; C:pseudopodium; IEA:UniProtKB-SubCell.
GO:0005198; F:structural molecule activity; IEA:InterPro.
26P53021    126   MSP1_GLORO Major sperm protein 1 OS=Globodera...560.009     38.5     32     52GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0031143; C:pseudopodium; IEA:UniProtKB-SubCell.
GO:0005198; F:structural molecule activity; IEA:InterPro.
27P53022    126   MSP2_GLORO Major sperm protein 2 OS=Globodera...560.023     37.4     30     50GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0031143; C:pseudopodium; IEA:UniProtKB-SubCell.
GO:0005198; F:structural molecule activity; IEA:InterPro.
28Q1ECE0    266   VAP41_ARATH Vesicle-associated protein 4-1 OS...360.025     38.9     47     64GO:0005886; C:plasma membrane; IDA:TAIR.
GO:0005198; F:structural molecule activity; IEA:InterPro.
GO:0006970; P:response to osmotic stress; IEP:TAIR.
29Q9CWP6    518   MSPD2_MOUSE Motile sperm domain-containing pr...630.04     38.5     35     59GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0005198; F:structural molecule activity; IEA:InterPro.
30Q8NHP6    518   MSPD2_HUMAN Motile sperm domain-containing pr...870.067     37.7     30     54GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0005198; F:structural molecule activity; IEA:InterPro.
31P13262    127   MSP1_ONCVO Major sperm protein 1 OS=Onchocerc...560.31     34.3     29     54GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0031143; C:pseudopodium; IEA:UniProtKB-SubCell.
GO:0005198; F:structural molecule activity; IEA:InterPro.
records
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