Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YER118C
Length:
367
Number of sequences:
5887
Description:
YER118C SHO1 SGDID:S000000920, Chr V from 399055-397952, Genome Release 64-1-1, reverse complement, Verified ORF, "Transmembrane osmosensor involved in activation of the Cdc42p- and MAP kinase-dependent filamentous growth pathway and the high-osmolarity glycerol response pathway; phosphorylated by Hog1p; interacts with Pbs2p, Msb2p, Hkr1p, and Ste11p"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
61C5GIQ8    296   SHO1_AJEDR High osmolarity signaling protein ...3376e-36     137     29     46GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0006950; P:response to stress; IEA:UniProtKB-KW.
62B9W8T5    398   SHO1_CANDC High osmolarity signaling protein ...602e-20     94.7     68     85GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0006950; P:response to stress; IEA:UniProtKB-KW.
63C4YDC4    385   SHO1_CANAW High osmolarity signaling protein ...602e-20     94.7     68     85GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0006950; P:response to stress; IEA:UniProtKB-KW.
64Q5AQ36    387   SHO1_CANAL High osmolarity signaling protein ...602e-20     94.7     68     85GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0000902; P:cell morphogenesis; IMP:CGD.::GO:0034599; P:cellular response to oxidative stress; IMP:CGD.::GO:0009272; P:fungal-type cell wall biogenesis; IMP:CGD.::GO:0031505; P:fungal-type cell wall organization; IMP:CGD.::GO:0007232; P:osmosensory signaling pathway via Sho1 osmosensor; IMP:CGD.::GO:0090033; P:positive regulation of filamentous growth; IMP:CGD.
65Q6CAC5    300   SHO1_YARLI High osmolarity signaling protein ...571e-17     85.9     65     82GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0006950; P:response to stress; IEA:UniProtKB-KW.
66D8PSG0    331   SHO1_SCHCM High osmolarity signaling protein ...3299e-27     112     27     42GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0006950; P:response to stress; IEA:UniProtKB-KW.
67Q4P9Q7    335   SHO1_USTMA High osmolarity signaling protein ...3573e-25     107     25     42GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0006950; P:response to stress; IEA:UniProtKB-KW.
68E7A253    343   SHO1_SPORE High osmolarity signaling protein ...980.00001     50.1     22     52GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0006950; P:response to stress; IEA:UniProtKB-KW.
69E6RET3    296   SHO1_CRYGW High osmolarity signaling protein ...1330.0004     45.4     27     46GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0006950; P:response to stress; IEA:UniProtKB-KW.
70Q99M51    377   NCK1_MOUSE Cytoplasmic protein NCK1 OS=Mus mu...380.13     37.7     39     63GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0012506; C:vesicle membrane; IDA:MGI.
GO:0019904; F:protein domain specific binding; IPI:MGI.
GO:0007015; P:actin filament organization; IMP:MGI.::GO:0016477; P:cell migration; IMP:MGI.::GO:0030032; P:lamellipodium assembly; IMP:MGI.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0006417; P:regulation of translation; IEA:UniProtKB-KW.
71P16333    377   NCK1_HUMAN Cytoplasmic protein NCK1 OS=Homo s...380.13     37.7     39     63GO:0005829; C:cytosol; TAS:Reactome.::GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; TAS:Reactome.
GO:0008093; F:cytoskeletal adaptor activity; NAS:UniProtKB.::GO:0005102; F:receptor binding; IPI:UniProtKB.::GO:0030159; F:receptor signaling complex scaffold activity; NAS:UniProtKB.
GO:0007411; P:axon guidance; TAS:Reactome.::GO:0030838; P:positive regulation of actin filament polymerization; IMP:UniProtKB.::GO:0042102; P:positive regulation of T cell proliferation; IMP:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.::GO:0006417; P:regulation of translation; IEA:UniProtKB-KW.::GO:0007172; P:signal complex assembly; NAS:UniProtKB.::GO:0042110; P:T cell activation; IMP:UniProtKB.::GO:0050852; P:T cell receptor signaling pathway; TAS:Reactome.
72Q05876    534   FYN_CHICK Tyrosine-protein kinase Fyn OS=Gall...570.00006     48.5     47     65
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC.::GO:0015631; F:tubulin binding; ISS:AgBase.
GO:0030900; P:forebrain development; ISS:AgBase.::GO:0001764; P:neuron migration; ISS:AgBase.::GO:0018108; P:peptidyl-tyrosine phosphorylation; ISS:AgBase.::GO:0008360; P:regulation of cell shape; ISS:AgBase.
73O55033    380   NCK2_MOUSE Cytoplasmic protein NCK2 OS=Mus mu...510.053     38.9     39     53GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.::GO:0012506; C:vesicle membrane; IDA:MGI.
GO:0007015; P:actin filament organization; IMP:MGI.::GO:0016477; P:cell migration; IMP:MGI.::GO:0030032; P:lamellipodium assembly; IMP:MGI.::GO:0006417; P:regulation of translation; IEA:UniProtKB-KW.
74A1Y2K1    537   FYN_PIG Tyrosine-protein kinase Fyn OS=Sus sc...560.00008     48.1     48     64GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC.
75P06241    537   FYN_HUMAN Tyrosine-protein kinase Fyn OS=Homo...560.00008     48.1     48     64GO:0005829; C:cytosol; TAS:Reactome.::GO:0005768; C:endosome; IDA:HGNC.::GO:0005886; C:plasma membrane; IDA:HGNC.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046875; F:ephrin receptor binding; IPI:UniProtKB.::GO:0001948; F:glycoprotein binding; IPI:BHF-UCL.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; NAS:UniProtKB.
GO:0007411; P:axon guidance; TAS:Reactome.::GO:0006816; P:calcium ion transport; NAS:UniProtKB.::GO:0007631; P:feeding behavior; TAS:ProtInc.::GO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW.::GO:0007243; P:intracellular protein kinase cascade; TAS:ProtInc.::GO:0007612; P:learning; TAS:ProtInc.::GO:0050900; P:leukocyte migration; TAS:Reactome.::GO:0030168; P:platelet activation; TAS:Reactome.::GO:0050690; P:regulation of defense response to virus by virus; TAS:Reactome.::GO:0031295; P:T cell costimulation; TAS:Reactome.::GO:0050852; P:T cell receptor signaling pathway; IDA:UniProtKB.::GO:0016032; P:viral reproduction; TAS:Reactome.
76P39688    537   FYN_MOUSE Tyrosine-protein kinase Fyn OS=Mus ...560.00008     48.1     48     64GO:0005829; C:cytosol; TAS:Reactome.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0044325; F:ion channel binding; IPI:BHF-UCL.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC.::GO:0015631; F:tubulin binding; IDA:MGI.
GO:0050798; P:activated T cell proliferation; IMP:MGI.::GO:0048813; P:dendrite morphogenesis; IMP:MGI.::GO:0050966; P:detection of mechanical stimulus involved in sensory perception of pain; IMP:MGI.::GO:0030900; P:forebrain development; IMP:MGI.::GO:0042552; P:myelination; TAS:MGI.::GO:0010629; P:negative regulation of gene expression; IMP:BHF-UCL.::GO:0042177; P:negative regulation of protein catabolic process; IMP:MGI.::GO:0001764; P:neuron migration; IMP:MGI.::GO:0018108; P:peptidyl-tyrosine phosphorylation; IDA:MGI.::GO:0046777; P:protein autophosphorylation; IDA:MGI.::GO:0008360; P:regulation of cell shape; IDA:MGI.::GO:0045471; P:response to ethanol; IGI:MGI.
77Q62844    537   FYN_RAT Tyrosine-protein kinase Fyn OS=Rattus...560.00008     48.1     48     64GO:0005829; C:cytosol; TAS:Reactome.::GO:0005792; C:microsome; IDA:RGD.::GO:0005739; C:mitochondrion; IDA:RGD.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.::GO:0014069; C:postsynaptic density; IDA:RGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0042609; F:CD4 receptor binding; IPI:RGD.::GO:0042610; F:CD8 receptor binding; IPI:RGD.::GO:0001948; F:glycoprotein binding; IPI:RGD.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC.::GO:0051428; F:peptide hormone receptor binding; IPI:RGD.::GO:0043548; F:phosphatidylinositol 3-kinase binding; IDA:RGD.::GO:0042608; F:T cell receptor binding; IDA:RGD.
GO:0071363; P:cellular response to growth factor stimulus; IEP:RGD.::GO:0071375; P:cellular response to peptide hormone stimulus; IEP:RGD.::GO:0035235; P:ionotropic glutamate receptor signaling pathway; TAS:RGD.::GO:2001240; P:negative regulation of extrinsic apoptotic signaling pathway in absence of ligand; IMP:UniProtKB.::GO:0018108; P:peptidyl-tyrosine phosphorylation; IDA:RGD.::GO:0046777; P:protein autophosphorylation; IDA:RGD.::GO:0042493; P:response to drug; IEP:RGD.
78A0JNB0    537   FYN_BOVIN Tyrosine-protein kinase Fyn OS=Bos ...560.00008     48.1     48     64GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC.
79Q6GM14    376   DBNLB_XENLA Drebrin-like protein B OS=Xenopus...800.0001     47.4     34     58GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0030027; C:lamellipodium; IEA:UniProtKB-SubCell.
GO:0003779; F:actin binding; IEA:UniProtKB-KW.
80P34109    1109   MYOD_DICDI Myosin ID heavy chain OS=Dictyoste...560.0001     48.1     48     64GO:0005938; C:cell cortex; IEA:UniProtKB-SubCell.::GO:0031252; C:cell leading edge; IDA:dictyBase.::GO:0016459; C:myosin complex; IEA:UniProtKB-KW.::GO:0031143; C:pseudopodium; IEA:UniProtKB-SubCell.
GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003774; F:motor activity; IEA:InterPro.
GO:0006935; P:chemotaxis; IEA:UniProtKB-KW.::GO:0006909; P:phagocytosis; IEA:UniProtKB-KW.
81Q92266    380   PEX13_PICPA Peroxisomal membrane protein PEX1...990.0001     47     28     52GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005778; C:peroxisomal membrane; IEA:UniProtKB-SubCell.
GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0016560; P:protein import into peroxisome matrix, docking; IEA:InterPro.
82O43639    380   NCK2_HUMAN Cytoplasmic protein NCK2 OS=Homo s...510.043     39.3     39     55GO:0005829; C:cytosol; TAS:Reactome.::GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.
GO:0008093; F:cytoskeletal adaptor activity; NAS:UniProtKB.::GO:0030159; F:receptor signaling complex scaffold activity; NAS:UniProtKB.
GO:0007411; P:axon guidance; TAS:Reactome.::GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:ProtInc.::GO:0008285; P:negative regulation of cell proliferation; TAS:ProtInc.::GO:0030838; P:positive regulation of actin filament polymerization; IMP:UniProtKB.::GO:0042102; P:positive regulation of T cell proliferation; IMP:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.::GO:0007176; P:regulation of epidermal growth factor-activated receptor activity; TAS:ProtInc.::GO:0006417; P:regulation of translation; IEA:UniProtKB-KW.::GO:0007172; P:signal complex assembly; NAS:UniProtKB.::GO:0042110; P:T cell activation; NAS:UniProtKB.
83P09324    541   YES_CHICK Tyrosine-protein kinase Yes OS=Gall...560.0002     46.6     48     66GO:0005829; C:cytosol; IEA:UniProtKB-SubCell.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC.
84Q15811    1721   ITSN1_HUMAN Intersectin-1 OS=Homo sapiens (Hu...540.019     40.8     31     63GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0005905; C:coated pit; IDA:UniProtKB.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0030027; C:lamellipodium; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IDA:UniProtKB.::GO:0045202; C:synapse; IEA:UniProtKB-KW.::GO:0019717; C:synaptosome; IEA:UniProtKB-SubCell.
GO:0005509; F:calcium ion binding; NAS:UniProtKB.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0070064; F:proline-rich region binding; IPI:UniProtKB.::GO:0032947; F:protein complex scaffold; IDA:UniProtKB.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro.
GO:0006915; P:apoptotic process; TAS:Reactome.::GO:0008624; P:induction of apoptosis by extracellular signals; TAS:Reactome.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.::GO:0048488; P:synaptic vesicle endocytosis; TAS:ProtInc.
85P09769    529   FGR_HUMAN Tyrosine-protein kinase Fgr OS=Homo...690.0003     46.2     42     62GO:0005829; C:cytosol; TAS:Reactome.::GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell.::GO:0005758; C:mitochondrial intermembrane space; IEA:UniProtKB-SubCell.::GO:0032587; C:ruffle membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0034988; F:Fc-gamma receptor I complex binding; IDA:UniProtKB.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IDA:UniProtKB.::GO:0001784; F:phosphotyrosine binding; ISS:UniProtKB.::GO:0019901; F:protein kinase binding; ISS:UniProtKB.
GO:0007596; P:blood coagulation; TAS:Reactome.::GO:0050830; P:defense response to Gram-positive bacterium; ISS:UniProtKB.::GO:0002768; P:immune response-regulating cell surface receptor signaling pathway; TAS:UniProtKB.::GO:0045087; P:innate immune response; IEA:UniProtKB-KW.::GO:0007229; P:integrin-mediated signaling pathway; IMP:UniProtKB.::GO:0018108; P:peptidyl-tyrosine phosphorylation; IDA:UniProtKB.::GO:0030335; P:positive regulation of cell migration; ISS:UniProtKB.::GO:0050715; P:positive regulation of cytokine secretion; ISS:UniProtKB.::GO:0043306; P:positive regulation of mast cell degranulation; ISS:UniProtKB.::GO:0043552; P:positive regulation of phosphatidylinositol 3-kinase activity; IMP:UniProtKB.::GO:0014068; P:positive regulation of phosphatidylinositol 3-kinase cascade; IMP:UniProtKB.::GO:0046777; P:protein autophosphorylation; IDA:UniProtKB.::GO:0008360; P:regulation of cell shape; ISS:UniProtKB.::GO:0045088; P:regulation of innate immune response; ISS:UniProtKB.::GO:0050764; P:regulation of phagocytosis; ISS:UniProtKB.::GO:0045859; P:regulation of protein kinase activity; ISS:UniProtKB.::GO:0009615; P:response to virus; TAS:ProtInc.
86Q07014    512   LYN_RAT Tyrosine-protein kinase Lyn OS=Rattus...510.0003     46.2     45     65GO:0034666; C:alpha2-beta1 integrin complex; IDA:RGD.::GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0005624; C:membrane fraction; IDA:RGD.::GO:0045121; C:membrane raft; IDA:RGD.::GO:0030061; C:mitochondrial crista; IDA:RGD.::GO:0005758; C:mitochondrial intermembrane space; IDA:RGD.::GO:0005634; C:nucleus; ISS:UniProtKB.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.::GO:0014069; C:postsynaptic density; IDA:RGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0043208; F:glycosphingolipid binding; IPI:RGD.::GO:0005178; F:integrin binding; IDA:RGD.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC.::GO:0051219; F:phosphoprotein binding; IPI:RGD.::GO:0005161; F:platelet-derived growth factor receptor binding; IPI:RGD.::GO:0031625; F:ubiquitin protein ligase binding; IPI:RGD.
GO:0001782; P:B cell homeostasis; ISS:UniProtKB.::GO:0034605; P:cellular response to heat; IEP:RGD.::GO:0050663; P:cytokine secretion; IMP:RGD.::GO:0097028; P:dendritic cell differentiation; ISS:UniProtKB.::GO:0030218; P:erythrocyte differentiation; ISS:UniProtKB.::GO:0002774; P:Fc receptor mediated inhibitory signaling pathway; ISS:UniProtKB.::GO:0002431; P:Fc receptor mediated stimulatory signaling pathway; ISS:UniProtKB.::GO:0002553; P:histamine secretion by mast cell; IMP:RGD.::GO:0045087; P:innate immune response; IEA:UniProtKB-KW.::GO:0031663; P:lipopolysaccharide-mediated signaling pathway; ISS:UniProtKB.::GO:0070373; P:negative regulation of ERK1 and ERK2 cascade; ISS:UniProtKB.::GO:0043407; P:negative regulation of MAP kinase activity; ISS:UniProtKB.::GO:0070667; P:negative regulation of mast cell proliferation; ISS:UniProtKB.::GO:0001933; P:negative regulation of protein phosphorylation; ISS:UniProtKB.::GO:0034136; P:negative regulation of toll-like receptor 2 signaling pathway; ISS:UniProtKB.::GO:0034144; P:negative regulation of toll-like receptor 4 signaling pathway; ISS:UniProtKB.::GO:0014003; P:oligodendrocyte development; IEP:RGD.::GO:0002576; P:platelet degranulation; ISS:UniProtKB.::GO:2000670; P:positive regulation of dendritic cell apoptotic process; ISS:UniProtKB.::GO:0060369; P:positive regulation of Fc receptor mediated stimulatory signaling pathway; IMP:RGD.::GO:0060252; P:positive regulation of glial cell proliferation; IDA:RGD.::GO:0070447; P:positive regulation of oligodendrocyte progenitor proliferation; IMP:RGD.::GO:0042531; P:positive regulation of tyrosine phosphorylation of STAT protein; ISS:UniProtKB.::GO:0050855; P:regulation of B cell receptor signaling pathway; ISS:UniProtKB.::GO:0045646; P:regulation of erythrocyte differentiation; ISS:UniProtKB.::GO:0043304; P:regulation of mast cell degranulation; ISS:UniProtKB.::GO:0090330; P:regulation of platelet aggregation; ISS:UniProtKB.::GO:0051279; P:regulation of release of sequestered calcium ion into cytosol; IMP:RGD.::GO:0043200; P:response to amino acid stimulus; IEP:RGD.::GO:0048678; P:response to axon injury; IEP:RGD.::GO:0009743; P:response to carbohydrate stimulus; IEP:RGD.::GO:0042493; P:response to drug; IEP:RGD.::GO:0032868; P:response to insulin stimulus; IEP:RGD.::GO:0014070; P:response to organic cyclic compound; IEP:RGD.::GO:0006991; P:response to sterol depletion; IEP:RGD.::GO:0009636; P:response to toxin; IEP:RGD.::GO:0002513; P:tolerance induction to self antigen; ISS:UniProtKB.
87Q62418    436   DBNL_MOUSE Drebrin-like protein OS=Mus muscul...570.0004     45.8     44     63GO:0005938; C:cell cortex; IDA:MGI.::GO:0030027; C:lamellipodium; IDA:UniProtKB.::GO:0001726; C:ruffle; IDA:UniProtKB.
GO:0051015; F:actin filament binding; IDA:UniProtKB.::GO:0019904; F:protein domain specific binding; IDA:MGI.
GO:0006897; P:endocytosis; IEA:UniProtKB-KW.::GO:0016601; P:Rac protein signal transduction; IDA:MGI.
88Q02977    536   YRK_CHICK Proto-oncogene tyrosine-protein kin...560.0004     45.8     45     68
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC.
89P25911    512   LYN_MOUSE Tyrosine-protein kinase Lyn OS=Mus ...510.0004     45.8     45     65GO:0005829; C:cytosol; TAS:Reactome.::GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IDA:UniProtKB.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005128; F:erythropoietin receptor binding; TAS:UniProtKB.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC.::GO:0017124; F:SH3 domain binding; IPI:MGI.
GO:0001782; P:B cell homeostasis; IMP:UniProtKB.::GO:0050853; P:B cell receptor signaling pathway; IDA:MGI.::GO:0097028; P:dendritic cell differentiation; IMP:UniProtKB.::GO:0030218; P:erythrocyte differentiation; IMP:UniProtKB.::GO:0002774; P:Fc receptor mediated inhibitory signaling pathway; IMP:UniProtKB.::GO:0002431; P:Fc receptor mediated stimulatory signaling pathway; IMP:UniProtKB.::GO:0042541; P:hemoglobin biosynthetic process; TAS:UniProtKB.::GO:0045087; P:innate immune response; IEA:UniProtKB-KW.::GO:0035556; P:intracellular signal transduction; IDA:MGI.::GO:0031663; P:lipopolysaccharide-mediated signaling pathway; IMP:UniProtKB.::GO:0030889; P:negative regulation of B cell proliferation; IMP:UniProtKB.::GO:0070373; P:negative regulation of ERK1 and ERK2 cascade; IMP:UniProtKB.::GO:0043407; P:negative regulation of MAP kinase activity; IMP:UniProtKB.::GO:0070667; P:negative regulation of mast cell proliferation; IMP:UniProtKB.::GO:0002762; P:negative regulation of myeloid leukocyte differentiation; IMP:UniProtKB.::GO:0001933; P:negative regulation of protein phosphorylation; IMP:UniProtKB.::GO:0034136; P:negative regulation of toll-like receptor 2 signaling pathway; IMP:UniProtKB.::GO:0034144; P:negative regulation of toll-like receptor 4 signaling pathway; IMP:UniProtKB.::GO:0031175; P:neuron projection development; IMP:MGI.::GO:0018108; P:peptidyl-tyrosine phosphorylation; IDA:UniProtKB.::GO:0002576; P:platelet degranulation; IMP:UniProtKB.::GO:0030335; P:positive regulation of cell migration; IMP:UniProtKB.::GO:2000670; P:positive regulation of dendritic cell apoptotic process; IMP:UniProtKB.::GO:0043552; P:positive regulation of phosphatidylinositol 3-kinase activity; IMP:UniProtKB.::GO:0042531; P:positive regulation of tyrosine phosphorylation of STAT protein; IMP:UniProtKB.::GO:0046777; P:protein autophosphorylation; IDA:UniProtKB.::GO:0002902; P:regulation of B cell apoptotic process; IMP:UniProtKB.::GO:0050855; P:regulation of B cell receptor signaling pathway; IMP:UniProtKB.::GO:0050707; P:regulation of cytokine secretion; IMP:UniProtKB.::GO:0045646; P:regulation of erythrocyte differentiation; IMP:UniProtKB.::GO:0050727; P:regulation of inflammatory response; IMP:UniProtKB.::GO:0043304; P:regulation of mast cell degranulation; IMP:UniProtKB.::GO:0090330; P:regulation of platelet aggregation; IMP:UniProtKB.::GO:0002513; P:tolerance induction to self antigen; IMP:UniProtKB.
90P13406    537   FYN_XENLA Tyrosine-protein kinase Fyn OS=Xeno...560.0004     45.8     46     64
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC.
GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW.
91Q9JHL4    436   DBNL_RAT Drebrin-like protein OS=Rattus norve...570.0004     45.8     44     63GO:0005938; C:cell cortex; ISS:UniProtKB.::GO:0030027; C:lamellipodium; ISS:UniProtKB.::GO:0014069; C:postsynaptic density; IDA:RGD.
GO:0006897; P:endocytosis; IEA:UniProtKB-KW.::GO:0016601; P:Rac protein signal transduction; ISS:UniProtKB.
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