Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YER118C
Length:
367
Number of sequences:
5887
Description:
YER118C SHO1 SGDID:S000000920, Chr V from 399055-397952, Genome Release 64-1-1, reverse complement, Verified ORF, "Transmembrane osmosensor involved in activation of the Cdc42p- and MAP kinase-dependent filamentous growth pathway and the high-osmolarity glycerol response pathway; phosphorylated by Hog1p; interacts with Pbs2p, Msb2p, Hkr1p, and Ste11p"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
301P31007    970   DLG1_DROME Disks large 1 tumor suppressor pro...580.71     35.8     34     55GO:0045179; C:apical cortex; IDA:FlyBase.::GO:0016323; C:basolateral plasma membrane; TAS:FlyBase.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0016328; C:lateral plasma membrane; IDA:FlyBase.::GO:0031594; C:neuromuscular junction; IDA:FlyBase.::GO:0048471; C:perinuclear region of cytoplasm; IDA:FlyBase.::GO:0045211; C:postsynaptic membrane; IDA:FlyBase.::GO:0005918; C:septate junction; NAS:FlyBase.::GO:0043195; C:terminal button; IDA:FlyBase.
GO:0005154; F:epidermal growth factor receptor binding; TAS:FlyBase.::GO:0004385; F:guanylate kinase activity; TAS:FlyBase.::GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW.::GO:0005198; F:structural molecule activity; TAS:FlyBase.
GO:0030714; P:anterior/posterior axis specification, follicular epithelium; IMP:BHF-UCL.::GO:0045167; P:asymmetric protein localization involved in cell fate determination; TAS:FlyBase.::GO:0045175; P:basal protein localization; IMP:FlyBase.::GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.::GO:0060581; P:cell fate commitment involved in pattern specification; IMP:BHF-UCL.::GO:0001708; P:cell fate specification; IMP:BHF-UCL.::GO:0008283; P:cell proliferation; TAS:FlyBase.::GO:0007391; P:dorsal closure; NAS:FlyBase.::GO:0051294; P:establishment of spindle orientation; IMP:FlyBase.::GO:0045197; P:establishment or maintenance of epithelial cell apical/basal polarity; NAS:FlyBase.::GO:0045196; P:establishment or maintenance of neuroblast polarity; TAS:FlyBase.::GO:0016332; P:establishment or maintenance of polarity of embryonic epithelium; TAS:FlyBase.::GO:0016336; P:establishment or maintenance of polarity of larval imaginal disc epithelium; NAS:FlyBase.::GO:0045475; P:locomotor rhythm; IMP:FlyBase.::GO:0008049; P:male courtship behavior; IMP:FlyBase.::GO:0001738; P:morphogenesis of a polarized epithelium; TAS:FlyBase.::GO:0008285; P:negative regulation of cell proliferation; TAS:FlyBase.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IMP:BHF-UCL.::GO:0007318; P:pole plasm protein localization; IMP:BHF-UCL.::GO:0046956; P:positive phototaxis; IMP:FlyBase.::GO:0030710; P:regulation of border follicle cell delamination; TAS:FlyBase.::GO:0051726; P:regulation of cell cycle; NAS:FlyBase.::GO:0042058; P:regulation of epidermal growth factor receptor signaling pathway; IMP:BHF-UCL.::GO:0046425; P:regulation of JAK-STAT cascade; IMP:BHF-UCL.::GO:0008593; P:regulation of Notch signaling pathway; IMP:BHF-UCL.::GO:0019991; P:septate junction assembly; TAS:FlyBase.::GO:0051124; P:synaptic growth at neuromuscular junction; IMP:FlyBase.::GO:0007268; P:synaptic transmission; IMP:FlyBase.
302Q8TC17    118   GRAPL_HUMAN GRB2-related adapter protein-like...580.73     33.5     33     57
303Q5ZLR6    764   ARHG6_CHICK Rho guanine nucleotide exchange f...640.73     35.8     34     58GO:0005622; C:intracellular; IEA:InterPro.
GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro.
GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro.
304Q5XHY7    523   STAM2_RAT Signal transducing adapter molecule...540.73     35.4     33     61GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell.
GO:0006886; P:intracellular protein transport; IEA:InterPro.
305Q0CJU8    597   HSE1_ASPTN Class E vacuolar protein-sorting m...690.77     35.4     30     52GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.
GO:0006886; P:intracellular protein transport; IEA:InterPro.
306P08032    2415   SPTA1_MOUSE Spectrin alpha chain, erythrocyte...630.8     35.8     30     57GO:0032437; C:cuticular plate; IDA:MGI.::GO:0016020; C:membrane; IDA:MGI.::GO:0008091; C:spectrin; IMP:MGI.::GO:0014731; C:spectrin-associated cytoskeleton; IMP:MGI.
GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0005509; F:calcium ion binding; IEA:InterPro.::GO:0046982; F:protein heterodimerization activity; IPI:MGI.
GO:0030036; P:actin cytoskeleton organization; IMP:MGI.::GO:0051693; P:actin filament capping; IEA:UniProtKB-KW.::GO:0030097; P:hemopoiesis; IMP:MGI.::GO:0002260; P:lymphocyte homeostasis; IMP:MGI.::GO:0007009; P:plasma membrane organization; IMP:MGI.::GO:0006779; P:porphyrin-containing compound biosynthetic process; IMP:MGI.::GO:0042102; P:positive regulation of T cell proliferation; IMP:MGI.::GO:0008360; P:regulation of cell shape; IMP:MGI.
307P15891    592   ABP1_YEAST Actin-binding protein OS=Saccharom...560.81     35.4     38     59GO:0030479; C:actin cortical patch; IDA:SGD.::GO:0043332; C:mating projection tip; IDA:SGD.
GO:0051015; F:actin filament binding; IDA:SGD.
GO:0000147; P:actin cortical patch assembly; IMP:SGD.::GO:0008104; P:protein localization; IMP:SGD.
308P0CR79    660   HSE1_CRYNB Class E vacuolar protein-sorting m...660.84     35.4     30     52GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.
GO:0006886; P:intracellular protein transport; IEA:InterPro.
309Q64355    560   EFS_MOUSE Embryonal Fyn-associated substrate ...590.91     35.4     34     56
GO:0017124; F:SH3 domain binding; IDA:MGI.
GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.
310Q6C2N2    685   HSE1_YARLI Class E vacuolar protein-sorting m...620.93     35.4     35     53GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.
GO:0006886; P:intracellular protein transport; IEA:InterPro.
311B5DFQ4    759   RHG26_XENTR Rho GTPase-activating protein 26 ...570.93     35.4     39     53GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell.
GO:0008093; F:cytoskeletal adaptor activity; IEA:InterPro.::GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0017124; F:SH3 domain binding; IEA:InterPro.
GO:0046847; P:filopodium assembly; IEA:InterPro.::GO:0007165; P:signal transduction; IEA:InterPro.
312Q08881    620   ITK_HUMAN Tyrosine-protein kinase ITK/TSK OS=...490.99     35     35     57GO:0005829; C:cytosol; TAS:Reactome.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IDA:UniProtKB.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0007202; P:activation of phospholipase C activity; ISS:UniProtKB.::GO:0002250; P:adaptive immune response; ISS:UniProtKB.::GO:0006968; P:cellular defense response; TAS:ProtInc.::GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0050852; P:T cell receptor signaling pathway; ISS:UniProtKB.
313Q21FH4    454   MIAB_SACD2 (Dimethylallyl)adenosine tRNA meth...840.99     35     33     46GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
GO:0006400; P:tRNA modification; IEA:InterPro.
314Q9TU19    565   NPHP1_CANFA Nephrocystin-1 OS=Canis familiari...491.1     35     37     57GO:0005912; C:adherens junction; IEA:UniProtKB-SubCell.::GO:0035085; C:cilium axoneme; IEA:UniProtKB-SubCell.::GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-KW.::GO:0005923; C:tight junction; IEA:UniProtKB-SubCell.
GO:0030030; P:cell projection organization; IEA:UniProtKB-KW.
315O43281    561   EFS_HUMAN Embryonal Fyn-associated substrate ...591.1     35     34     56GO:0005737; C:cytoplasm; TAS:ProtInc.
GO:0017124; F:SH3 domain binding; IEA:UniProtKB-KW.
GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.::GO:0035556; P:intracellular signal transduction; TAS:ProtInc.
316P20929    6669   NEBU_HUMAN Nebulin OS=Homo sapiens (Human). G...561.2     35     38     61GO:0015629; C:actin cytoskeleton; TAS:ProtInc.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0030018; C:Z disc; IDA:UniProtKB.
GO:0003779; F:actin binding; IEA:UniProtKB-KW.::GO:0008307; F:structural constituent of muscle; TAS:ProtInc.
GO:0030049; P:muscle filament sliding; TAS:Reactome.::GO:0007517; P:muscle organ development; TAS:ProtInc.::GO:0030832; P:regulation of actin filament length; NAS:UniProtKB.::GO:0007525; P:somatic muscle development; NAS:UniProtKB.
317Q8K4I3    771   ARHG6_MOUSE Rho guanine nucleotide exchange f...681.2     35     35     54GO:0005622; C:intracellular; IEA:InterPro.
GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro.
GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro.
318Q8IVI9    506   NOSTN_HUMAN Nostrin OS=Homo sapiens (Human). ...541.2     34.7     37     57GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0030666; C:endocytic vesicle membrane; TAS:Reactome.::GO:0005886; C:plasma membrane; TAS:Reactome.
GO:0005515; F:protein binding; IPI:IntAct.
GO:0006897; P:endocytosis; IEA:UniProtKB-KW.::GO:0046209; P:nitric oxide metabolic process; TAS:Reactome.::GO:0050999; P:regulation of nitric-oxide synthase activity; TAS:Reactome.::GO:0044281; P:small molecule metabolic process; TAS:Reactome.
319P42682    527   TXK_MOUSE Tyrosine-protein kinase TXK OS=Mus ...531.2     34.7     36     49GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC.
GO:0007202; P:activation of phospholipase C activity; IMP:UniProtKB.::GO:0002250; P:adaptive immune response; IMP:UniProtKB.::GO:0032609; P:interferon-gamma production; IGI:MGI.::GO:0032633; P:interleukin-4 production; IGI:MGI.::GO:0001865; P:NK T cell differentiation; IGI:MGI.::GO:0050852; P:T cell receptor signaling pathway; IMP:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
320Q5XXR3    772   ARHG6_RAT Rho guanine nucleotide exchange fac...681.2     35     35     54GO:0005622; C:intracellular; IEA:InterPro.
GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005089; F:Rho guanyl-nucleotide exchange factor activity; IEA:InterPro.
GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0035023; P:regulation of Rho protein signal transduction; IEA:InterPro.
321P38479    617   ABP1_SACEX Actin-binding protein OS=Saccharom...561.3     34.7     36     59GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.
GO:0003779; F:actin binding; IEA:UniProtKB-KW.
322A6QLK6    217   GRAP_BOVIN GRB2-related adapter protein OS=Bo...502.2     33.5     30     58
323Q8CIH5    1265   PLCG2_MOUSE 1-phosphatidylinositol 4,5-bispho...651.7     34.7     37     48GO:0005829; C:cytosol; IMP:UniProtKB.::GO:0005886; C:plasma membrane; ISS:UniProtKB.
GO:0004435; F:phosphatidylinositol phospholipase C activity; ISS:UniProtKB.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW.
GO:0032237; P:activation of store-operated calcium channel activity; IMP:MGI.::GO:0050853; P:B cell receptor signaling pathway; IMP:UniProtKB.::GO:0002316; P:follicular B cell differentiation; IMP:MGI.::GO:0032959; P:inositol trisphosphate biosynthetic process; IDA:MGI.::GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0043069; P:negative regulation of programmed cell death; IMP:MGI.::GO:0006661; P:phosphatidylinositol biosynthetic process; ISS:UniProtKB.::GO:0009395; P:phospholipid catabolic process; IEA:InterPro.::GO:0010468; P:regulation of gene expression; IMP:MGI.::GO:0051209; P:release of sequestered calcium ion into cytosol; IMP:UniProtKB.::GO:0032496; P:response to lipopolysaccharide; IDA:MGI.::GO:0050852; P:T cell receptor signaling pathway; IDA:MGI.
324P24135    1265   PLCG2_RAT 1-phosphatidylinositol 4,5-bisphosp...651.7     34.7     37     48GO:0005624; C:membrane fraction; IDA:RGD.::GO:0005886; C:plasma membrane; ISS:UniProtKB.
GO:0004435; F:phosphatidylinositol phospholipase C activity; IDA:RGD.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:RGD.::GO:0004871; F:signal transducer activity; IEA:UniProtKB-KW.
GO:0035556; P:intracellular signal transduction; IEA:InterPro.::GO:0006661; P:phosphatidylinositol biosynthetic process; ISS:UniProtKB.::GO:0009395; P:phospholipid catabolic process; IEA:InterPro.::GO:0051209; P:release of sequestered calcium ion into cytosol; ISS:UniProtKB.::GO:0033198; P:response to ATP; IDA:RGD.::GO:0032026; P:response to magnesium ion; IDA:RGD.
325Q8AXV0    367   SH3G1_CHICK Endophilin-A2 OS=Gallus gallus (C...561.8     34.3     30     66GO:0031901; C:early endosome membrane; IEA:UniProtKB-SubCell.
GO:0008289; F:lipid binding; IEA:UniProtKB-KW.
GO:0006897; P:endocytosis; IEA:UniProtKB-KW.
326Q5R8P5    365   SHLB1_PONAB Endophilin-B1 OS=Pongo abelii (Su...871.9     33.9     29     49GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0005741; C:mitochondrial outer membrane; IEA:UniProtKB-SubCell.
GO:0008093; F:cytoskeletal adaptor activity; IEA:InterPro.::GO:0008289; F:lipid binding; IEA:UniProtKB-KW.::GO:0017124; F:SH3 domain binding; IEA:InterPro.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0046847; P:filopodium assembly; IEA:InterPro.::GO:0007165; P:signal transduction; IEA:InterPro.
327Q9Y371    365   SHLB1_HUMAN Endophilin-B1 OS=Homo sapiens (Hu...871.9     33.9     29     49GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0005741; C:mitochondrial outer membrane; IEA:UniProtKB-SubCell.
GO:0008093; F:cytoskeletal adaptor activity; IEA:InterPro.::GO:0042802; F:identical protein binding; IPI:IntAct.::GO:0008289; F:lipid binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0042803; F:protein homodimerization activity; IPI:HGNC.::GO:0017124; F:SH3 domain binding; IEA:InterPro.
GO:0006916; P:anti-apoptosis; IDA:HGNC.::GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0046847; P:filopodium assembly; IEA:InterPro.::GO:0032461; P:positive regulation of protein oligomerization; IDA:UniProtKB.::GO:0051259; P:protein oligomerization; IDA:UniProtKB.::GO:0007165; P:signal transduction; IEA:InterPro.
328P34416    335   LASP1_CAEEL LIM and SH3 domain protein F42H10...671.9     33.9     36     52
GO:0008270; F:zinc ion binding; IEA:InterPro.
329A4RF61    718   HSE1_MAGO7 Class E vacuolar protein-sorting m...692     34.3     32     57GO:0010008; C:endosome membrane; IEA:UniProtKB-SubCell.
GO:0006886; P:intracellular protein transport; IEA:InterPro.
330P41239    450   CSK_CHICK Tyrosine-protein kinase CSK OS=Gall...442     33.9     34     61GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004715; F:non-membrane spanning protein tyrosine kinase activity; IEA:EC.
331Q9JLQ0    637   CD2AP_MOUSE CD2-associated protein OS=Mus mus...542.1     34.3     31     54GO:0005829; C:cytosol; TAS:Reactome.::GO:0005886; C:plasma membrane; IDA:MGI.::GO:0001726; C:ruffle; IEA:UniProtKB-SubCell.
GO:0017124; F:SH3 domain binding; IEA:UniProtKB-KW.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.
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