Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YER116C
Length:
274
Number of sequences:
5887
Description:
YER116C SLX8 SGDID:S000000918, Chr V from 396172-395348, Genome Release 64-1-1, reverse complement, Verified ORF, "Subunit of the Slx5-Slx8 SUMO-targeted ubiquitin ligase (STUbL) complex; stimulated by prior attachment of SUMO to the substrate; contains a C-terminal RING domain"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
1P40072    274   SLX8_YEAST E3 ubiquitin-protein ligase comple...2740     567     100     100GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.::GO:0000151; C:ubiquitin ligase complex; IDA:SGD.
GO:0005515; F:protein binding; IPI:IntAct.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:SGD.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0016925; P:protein sumoylation; IMP:SGD.::GO:0000723; P:telomere maintenance; IMP:SGD.
2Q5XI59    802   RNF10_RAT RING finger protein 10 OS=Rattus no...570.00000001     59.3     39     60GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IDA:UniProtKB.
GO:0044212; F:transcription regulatory region DNA binding; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0010626; P:negative regulation of Schwann cell proliferation; IDA:UniProtKB.::GO:0031643; P:positive regulation of myelination; IMP:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
3Q32NQ8    756   RNF10_XENLA RING finger protein 10 OS=Xenopus...570.00000001     58.9     37     60GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0044212; F:transcription regulatory region DNA binding; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0010626; P:negative regulation of Schwann cell proliferation; ISS:UniProtKB.::GO:0031643; P:positive regulation of myelination; ISS:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
4Q08E13    810   RNF10_BOVIN RING finger protein 10 OS=Bos tau...570.00000004     57.8     37     60GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0008270; F:zinc ion binding; IEA:InterPro.
5Q3UIW5    804   RNF10_MOUSE RING finger protein 10 OS=Mus mus...570.00000004     57.8     37     60GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0044212; F:transcription regulatory region DNA binding; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0010626; P:negative regulation of Schwann cell proliferation; ISS:UniProtKB.::GO:0031643; P:positive regulation of myelination; ISS:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
6Q8N5U6    811   RNF10_HUMAN RING finger protein 10 OS=Homo sa...570.00000004     57.8     37     60GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0044212; F:transcription regulatory region DNA binding; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0010626; P:negative regulation of Schwann cell proliferation; ISS:UniProtKB.::GO:0031643; P:positive regulation of myelination; ISS:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
7Q9FF61    881   SM3L1_ARATH Putative SWI/SNF-related matrix-a...580.000003     52     34     52GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:InterPro.::GO:0004386; F:helicase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
8P87176    269   SLX8_SCHPO E3 ubiquitin-protein ligase comple...690.000007     50.1     33     52GO:0033768; C:SUMO-targeted ubiquitin ligase complex; IPI:PomBase.
GO:0005515; F:protein binding; IPI:PomBase.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:PomBase.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0000077; P:DNA damage checkpoint; IMP:PomBase.::GO:0006310; P:DNA recombination; IGI:PomBase.::GO:0033234; P:negative regulation of protein sumoylation; IMP:PomBase.
9Q99942    180   RNF5_HUMAN E3 ubiquitin-protein ligase RNF5 O...690.00003     47     33     55GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0031966; C:mitochondrial membrane; IEA:UniProtKB-SubCell.
GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; TAS:ProtInc.
GO:0071712; P:ER-associated misfolded protein catabolic process; IMP:UniProtKB.::GO:0070936; P:protein K48-linked ubiquitination; IDA:UniProtKB.::GO:0070534; P:protein K63-linked ubiquitination; IDA:UniProtKB.
10Q5M807    180   RNF5_RAT E3 ubiquitin-protein ligase RNF5 OS=...690.00003     47     33     57GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0031966; C:mitochondrial membrane; IEA:UniProtKB-SubCell.
GO:0008270; F:zinc ion binding; IEA:InterPro.
11O35445    180   RNF5_MOUSE E3 ubiquitin-protein ligase RNF5 O...690.00003     47     33     57GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0031966; C:mitochondrial membrane; IEA:UniProtKB-SubCell.
GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0071712; P:ER-associated misfolded protein catabolic process; ISS:UniProtKB.::GO:0070534; P:protein K63-linked ubiquitination; ISS:UniProtKB.
12Q9R1A8    733   RFWD2_MOUSE E3 ubiquitin-protein ligase RFWD2...400.0001     46.6     45     60GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:BHF-UCL.::GO:0008270; F:zinc ion binding; IEA:InterPro.
13Q8NHY2    731   RFWD2_HUMAN E3 ubiquitin-protein ligase RFWD2...380.0001     46.6     47     61GO:0005813; C:centrosome; IDA:HPA.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0005925; C:focal adhesion; IDA:HPA.::GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006977; P:DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest; TAS:Reactome.
14Q9P3U8    468   YJ95_SCHPO Uncharacterized RING finger protei...550.0003     45.4     35     47GO:0005634; C:nucleus; IDA:PomBase.::GO:0005816; C:spindle pole body; IDA:PomBase.
GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0034080; P:CenH3-containing nucleosome assembly at centromere; ISS:PomBase.::GO:0006368; P:transcription elongation from RNA polymerase II promoter; ISS:PomBase.
15Q91YT2    192   RN185_MOUSE E3 ubiquitin-protein ligase RNF18...500.0005     43.5     38     64GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005741; C:mitochondrial outer membrane; IEA:UniProtKB-SubCell.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006914; P:autophagy; IEA:UniProtKB-KW.
16P93471    672   COP1_PEA E3 ubiquitin-protein ligase COP1 OS=...440.0006     44.7     39     55GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0009585; P:red, far-red light phototransduction; IEA:UniProtKB-KW.
17Q568Y3    192   RN185_RAT E3 ubiquitin-protein ligase RNF185 ...550.001     42.7     36     60GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005741; C:mitochondrial outer membrane; IEA:UniProtKB-SubCell.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006914; P:autophagy; IEA:UniProtKB-KW.
18Q5ZIR9    194   RN185_CHICK E3 ubiquitin-protein ligase RNF18...500.001     42.7     38     64GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005741; C:mitochondrial outer membrane; IEA:UniProtKB-SubCell.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006914; P:autophagy; IEA:UniProtKB-KW.
19O94271    673   YORN_SCHPO Uncharacterized RING finger protei...710.001     43.5     34     44GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.
GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0016567; P:protein ubiquitination; NAS:PomBase.::GO:0006366; P:transcription from RNA polymerase II promoter; ISS:PomBase.
20Q96GF1    192   RN185_HUMAN E3 ubiquitin-protein ligase RNF18...550.001     42.4     36     60GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005741; C:mitochondrial outer membrane; IEA:UniProtKB-SubCell.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006914; P:autophagy; IEA:UniProtKB-KW.
21Q6PCN7    1003   HLTF_MOUSE Helicase-like transcription factor...550.001     43.5     33     56GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016887; F:ATPase activity; IDA:MGI.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0004386; F:helicase activity; IEA:UniProtKB-KW.::GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0006357; P:regulation of transcription from RNA polymerase II promoter; IDA:MGI.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
22P93030    193   RMA2_ARATH E3 ubiquitin-protein ligase RMA2 O...640.002     42     33     52GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0005515; F:protein binding; IPI:TAIR.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:TAIR.::GO:0008270; F:zinc ion binding; IEA:InterPro.
23Q5RFK9    192   RN185_PONAB E3 ubiquitin-protein ligase RNF18...550.002     42     36     60GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005741; C:mitochondrial outer membrane; IEA:UniProtKB-SubCell.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006914; P:autophagy; IEA:UniProtKB-KW.
24Q69ZS0    1063   PZRN3_MOUSE E3 ubiquitin-protein ligase PDZRN...680.002     43.1     31     50GO:0031594; C:neuromuscular junction; IDA:UniProtKB.
GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007528; P:neuromuscular junction development; IMP:UniProtKB.
25Q9UPQ7    1066   PZRN3_HUMAN E3 ubiquitin-protein ligase PDZRN...680.002     43.1     31     50
GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
26Q6BLM3    491   RAD18_DEBHA Postreplication repair E3 ubiquit...610.002     42.7     33     56GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003684; F:damaged DNA binding; IEA:InterPro.::GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
27Q9FNI6    1029   SM3L2_ARATH Putative SWI/SNF-related matrix-a...970.002     43.1     29     42GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:InterPro.::GO:0004386; F:helicase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0009294; P:DNA mediated transformation; IMP:TAIR.::GO:0000724; P:double-strand break repair via homologous recombination; IMP:TAIR.
28Q8GUK7    243   RMA3_ARATH E3 ubiquitin-protein ligase RMA3 O...590.003     41.6     31     59GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0004842; F:ubiquitin-protein ligase activity; IDA:TAIR.::GO:0008270; F:zinc ion binding; IEA:InterPro.
29Q6PC78    194   RN185_DANRE E3 ubiquitin-protein ligase RNF18...500.003     41.2     38     64GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005741; C:mitochondrial outer membrane; IEA:UniProtKB-SubCell.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006914; P:autophagy; IEA:UniProtKB-KW.
30Q6R567    252   RMA1_CAPAN E3 ubiquitin-protein ligase RMA1H1...750.005     41.2     31     53GO:0005789; C:endoplasmic reticulum membrane; IDA:UniProtKB.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0004842; F:ubiquitin-protein ligase activity; IMP:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0043161; P:proteasomal ubiquitin-dependent protein catabolic process; IDA:UniProtKB.::GO:0009409; P:response to cold; IEP:UniProtKB.::GO:0009723; P:response to ethylene stimulus; IEP:UniProtKB.::GO:0006970; P:response to osmotic stress; IEP:UniProtKB.::GO:0009414; P:response to water deprivation; IEP:UniProtKB.::GO:0009611; P:response to wounding; IEP:UniProtKB.
31Q3ZCC3    542   TRAF6_BOVIN TNF receptor-associated factor 6 ...880.005     41.6     31     47GO:0005938; C:cell cortex; IEA:UniProtKB-SubCell.
GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0070534; P:protein K63-linked ubiquitination; ISS:UniProtKB.::GO:0042981; P:regulation of apoptotic process; IEA:InterPro.
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