Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YER116C
Length:
274
Number of sequences:
5887
Description:
YER116C SLX8 SGDID:S000000918, Chr V from 396172-395348, Genome Release 64-1-1, reverse complement, Verified ORF, "Subunit of the Slx5-Slx8 SUMO-targeted ubiquitin ligase (STUbL) complex; stimulated by prior attachment of SUMO to the substrate; contains a C-terminal RING domain"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
181P34537    837   BRE1_CAEEL E3 ubiquitin-protein ligase bre-1 ...362.4     33.5     36     53GO:0005634; C:nucleus; IDA:UniProtKB.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0031624; F:ubiquitin conjugating enzyme binding; IPI:WormBase.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006915; P:apoptotic process; IMP:WormBase.::GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0006664; P:glycolipid metabolic process; IMP:UniProtKB.::GO:0040007; P:growth; IMP:WormBase.::GO:0040035; P:hermaphrodite genitalia development; IMP:WormBase.::GO:0040011; P:locomotion; IMP:WormBase.::GO:0002009; P:morphogenesis of an epithelium; IMP:WormBase.::GO:0040010; P:positive regulation of growth rate; IMP:WormBase.::GO:0040025; P:vulval development; IMP:WormBase.
182Q28DL4    558   TRAF6_XENTR TNF receptor-associated factor 6 ...312.4     33.1     42     55GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0070534; P:protein K63-linked ubiquitination; ISS:UniProtKB.::GO:0042981; P:regulation of apoptotic process; IEA:InterPro.::GO:0007165; P:signal transduction; IEA:InterPro.
183Q86XT4    487   TRI50_HUMAN E3 ubiquitin-protein ligase TRIM5...292.5     33.1     45     59GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0043231; C:intracellular membrane-bounded organelle; IDA:HPA.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
184P0C775    239   P28_VACC8 E3 ubiquitin-protein ligase p28-lik...802.5     32.7     24     43GO:0030430; C:host cell cytoplasm; IEA:UniProtKB-SubCell.
GO:0016881; F:acid-amino acid ligase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW.
185Q49PZ0    239   P28_VACC0 E3 ubiquitin ligase p28-like OS=Vac...802.5     32.7     24     43GO:0030430; C:host cell cytoplasm; IEA:UniProtKB-SubCell.
GO:0016881; F:acid-amino acid ligase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW.
186Q99PP6    485   TR34A_MOUSE Tripartite motif-containing prote...542.6     33.1     31     50GO:0005622; C:intracellular; IEA:InterPro.
GO:0008270; F:zinc ion binding; IEA:InterPro.
187P15533    496   TR30A_MOUSE Tripartite motif-containing prote...542.6     33.1     31     46GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0032715; P:negative regulation of interleukin-6 production; IMP:UniProtKB.::GO:2000378; P:negative regulation of reactive oxygen species metabolic process; IMP:UniProtKB.::GO:0034122; P:negative regulation of toll-like receptor signaling pathway; IMP:UniProtKB.::GO:0032720; P:negative regulation of tumor necrosis factor production; IMP:UniProtKB.::GO:0045732; P:positive regulation of protein catabolic process; IMP:UniProtKB.::GO:0051865; P:protein autoubiquitination; IMP:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
188P87607    242   P28_CWPXG E3 ubiquitin-protein ligase p28-lik...832.6     32.7     27     45GO:0030430; C:host cell cytoplasm; IEA:UniProtKB-SubCell.
GO:0016881; F:acid-amino acid ligase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW.
189Q19189    359   PEX12_CAEEL Putative peroxisome assembly prot...382.7     33.1     42     61GO:0005779; C:integral to peroxisomal membrane; IEA:InterPro.
GO:0008022; F:protein C-terminus binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0040007; P:growth; IMP:WormBase.::GO:0002119; P:nematode larval development; IMP:WormBase.::GO:0040010; P:positive regulation of growth rate; IMP:WormBase.::GO:0006625; P:protein targeting to peroxisome; IEA:InterPro.
190Q810I2    483   TRI50_MOUSE E3 ubiquitin-protein ligase TRIM5...512.7     33.1     37     47GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
191Q85318    241   P28_ECTVM E3 ubiquitin-protein ligase p28 OS=...802.8     32.7     24     43GO:0030430; C:host cell cytoplasm; IEA:UniProtKB-SubCell.
GO:0016881; F:acid-amino acid ligase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW.
192A2XW69    884   BRE1A_ORYSI E3 ubiquitin-protein ligase BRE1-...532.9     33.1     30     51GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0008270; F:zinc ion binding; IEA:InterPro.
193Q17RB8    773   LONF1_HUMAN LON peptidase N-terminal domain a...823     33.1     30     45
GO:0004176; F:ATP-dependent peptidase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006508; P:proteolysis; IEA:InterPro.
194Q7XU27    884   BRE1A_ORYSJ E3 ubiquitin-protein ligase BRE1-...533.1     33.1     30     51GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0008270; F:zinc ion binding; IEA:InterPro.
195Q9M9L0    84   APC11_ARATH Anaphase-promoting complex subuni...593.4     30.8     31     44GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005515; F:protein binding; IPI:IntAct.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.
196Q14258    630   TRI25_HUMAN E3 ubiquitin/ISG15 ligase TRIM25 ...303.4     32.7     47     60GO:0030054; C:cell junction; IDA:HPA.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0005634; C:nucleus; IDA:HPA.
GO:0005515; F:protein binding; IPI:IntAct.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:ProtInc.::GO:0004842; F:ubiquitin-protein ligase activity; IEA:EC.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0045087; P:innate immune response; TAS:Reactome.::GO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW.::GO:0032480; P:negative regulation of type I interferon production; TAS:Reactome.::GO:0009615; P:response to virus; IEA:UniProtKB-KW.
197Q9D4H7    753   LONF3_MOUSE LON peptidase N-terminal domain a...973.6     32.7     29     40
GO:0004176; F:ATP-dependent peptidase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006508; P:proteolysis; IEA:InterPro.
198B0BLU1    535   RN168_XENTR E3 ubiquitin-protein ligase RNF16...483.7     32.7     33     40GO:0005634; C:nucleus; ISS:UniProtKB.::GO:0000151; C:ubiquitin ligase complex; ISS:UniProtKB.
GO:0003682; F:chromatin binding; ISS:UniProtKB.::GO:0042393; F:histone binding; ISS:UniProtKB.::GO:0043130; F:ubiquitin binding; ISS:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006302; P:double-strand break repair; ISS:UniProtKB.::GO:0070535; P:histone H2A K63-linked ubiquitination; ISS:UniProtKB.::GO:0045739; P:positive regulation of DNA repair; ISS:UniProtKB.::GO:0010212; P:response to ionizing radiation; ISS:UniProtKB.
199Q810I1    483   TRI50_RAT E3 ubiquitin-protein ligase TRIM50 ...263.8     32.7     50     62GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
200Q149N8    1683   SHPRH_HUMAN E3 ubiquitin-protein ligase SHPRH...653.9     32.7     31     49GO:0000786; C:nucleosome; IEA:InterPro.::GO:0005634; C:nucleus; IEA:InterPro.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:InterPro.::GO:0004386; F:helicase activity; IEA:UniProtKB-KW.::GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0006334; P:nucleosome assembly; IEA:InterPro.
201Q94981    503   ARI1_DROME Protein ariadne-1 OS=Drosophila me...464     32.7     33     46GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
202O88846    194   RNF4_RAT E3 ubiquitin-protein ligase RNF4 OS=...554     32     33     44GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0016605; C:PML body; IEA:UniProtKB-SubCell.
GO:0050681; F:androgen receptor binding; IPI:RGD.::GO:0003677; F:DNA binding; IDA:UniProtKB.::GO:0030331; F:estrogen receptor binding; IDA:RGD.::GO:0031491; F:nucleosome binding; IDA:UniProtKB.::GO:0033142; F:progesterone receptor binding; IPI:RGD.::GO:0032184; F:SUMO polymer binding; IPI:UniProtKB.::GO:0017025; F:TBP-class protein binding; TAS:RGD.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; ISS:UniProtKB.::GO:0043161; P:proteasomal ubiquitin-dependent protein catabolic process; ISS:UniProtKB.::GO:0051865; P:protein autoubiquitination; IMP:UniProtKB.::GO:0070979; P:protein K11-linked ubiquitination; IDA:UniProtKB.::GO:0070936; P:protein K48-linked ubiquitination; IDA:UniProtKB.::GO:0085020; P:protein K6-linked ubiquitination; IDA:UniProtKB.::GO:0070534; P:protein K63-linked ubiquitination; IDA:UniProtKB.::GO:0090234; P:regulation of kinetochore assembly; ISS:UniProtKB.::GO:0090169; P:regulation of spindle assembly; ISS:UniProtKB.::GO:0046685; P:response to arsenic-containing substance; IDA:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
203P14373    513   TRI27_HUMAN Zinc finger protein RFP OS=Homo s...344.1     32.7     35     53GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0005887; C:integral to plasma membrane; TAS:ProtInc.::GO:0005624; C:membrane fraction; TAS:ProtInc.::GO:0031965; C:nuclear membrane; IDA:MGI.::GO:0016605; C:PML body; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004714; F:transmembrane receptor protein tyrosine kinase activity; TAS:ProtInc.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0008283; P:cell proliferation; TAS:ProtInc.::GO:0072643; P:interferon-gamma secretion; IMP:UniProtKB.::GO:0002820; P:negative regulation of adaptive immune response; IMP:UniProtKB.::GO:0090281; P:negative regulation of calcium ion import; IMP:UniProtKB.::GO:0045814; P:negative regulation of gene expression, epigenetic; IDA:MGI.::GO:1900041; P:negative regulation of interleukin-2 secretion; IMP:UniProtKB.::GO:0006469; P:negative regulation of protein kinase activity; IDA:UniProtKB.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:MGI.::GO:0032720; P:negative regulation of tumor necrosis factor production; IMP:UniProtKB.::GO:0070206; P:protein trimerization; IDA:UniProtKB.::GO:0007283; P:spermatogenesis; TAS:ProtInc.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
204O13747    547   EPT1_SCHPO RING finger protein ETP1 homolog O...494.1     32.7     39     51GO:0005829; C:cytosol; IDA:PomBase.
GO:0008270; F:zinc ion binding; IEA:InterPro.
205B5DF45    530   TRAF6_RAT TNF receptor-associated factor 6 OS...614.1     32.3     33     46GO:0005938; C:cell cortex; IEA:UniProtKB-SubCell.
GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0070498; P:interleukin-1-mediated signaling pathway; IMP:RGD.::GO:0007254; P:JNK cascade; IMP:RGD.::GO:0048661; P:positive regulation of smooth muscle cell proliferation; IMP:RGD.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IMP:RGD.::GO:0006461; P:protein complex assembly; IMP:RGD.::GO:0070534; P:protein K63-linked ubiquitination; ISS:UniProtKB.::GO:0042981; P:regulation of apoptotic process; IEA:InterPro.
206P38748    585   ETP1_YEAST RING finger protein ETP1 OS=Saccha...494.3     32.3     37     49GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0008139; F:nuclear localization sequence binding; IDA:SGD.::GO:0043130; F:ubiquitin binding; IDA:SGD.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0045471; P:response to ethanol; IMP:SGD.
207Q6IWL4    542   TRAF6_DANRE TNF receptor-associated factor 6 ...274.3     32.3     48     59GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0045087; P:innate immune response; IMP:ZFIN.::GO:0045893; P:positive regulation of transcription, DNA-dependent; IDA:ZFIN.::GO:0070534; P:protein K63-linked ubiquitination; ISS:UniProtKB.::GO:0042981; P:regulation of apoptotic process; IEA:InterPro.::GO:0009617; P:response to bacterium; IDA:ZFIN.::GO:0009615; P:response to virus; IDA:ZFIN.::GO:0007165; P:signal transduction; IEA:InterPro.
208Q5C8T8    493   TRIM5_PONAB Tripartite motif-containing prote...564.4     32.3     36     45GO:0000932; C:cytoplasmic mRNA processing body; IEA:UniProtKB-SubCell.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
209Q6DJN2    556   TRF6B_XENLA TNF receptor-associated factor 6-...274.4     32.3     48     56GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007250; P:activation of NF-kappaB-inducing kinase activity; IDA:UniProtKB.::GO:0070534; P:protein K63-linked ubiquitination; ISS:UniProtKB.::GO:0042981; P:regulation of apoptotic process; IEA:InterPro.
210Q6CSS6    229   CWC24_KLULA Pre-mRNA-splicing factor CWC24 OS...374.5     32     30     51GO:0005681; C:spliceosomal complex; IEA:UniProtKB-KW.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
211Q2YEM9    493   TRIM5_PONPY Tripartite motif-containing prote...564.5     32.3     36     45GO:0000932; C:cytoplasmic mRNA processing body; IEA:UniProtKB-SubCell.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
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