Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YER116C
Length:
274
Number of sequences:
5887
Description:
YER116C SLX8 SGDID:S000000918, Chr V from 396172-395348, Genome Release 64-1-1, reverse complement, Verified ORF, "Subunit of the Slx5-Slx8 SUMO-targeted ubiquitin ligase (STUbL) complex; stimulated by prior attachment of SUMO to the substrate; contains a C-terminal RING domain"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
121Q12161    406   PSH1_YEAST RING finger protein PSH1 OS=Saccha...560.59     35     32     46GO:0000775; C:chromosome, centromeric region; IDA:SGD.::GO:0005634; C:nucleus; IDA:SGD.
GO:0004842; F:ubiquitin-protein ligase activity; IDA:SGD.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IDA:SGD.
122Q8CJB9    1002   BRE1B_RAT E3 ubiquitin-protein ligase BRE1B O...480.63     35.4     40     52GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0019717; C:synaptosome; IDA:RGD.
GO:0032403; F:protein complex binding; IDA:RGD.::GO:0017075; F:syntaxin-1 binding; IPI:RGD.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:RGD.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006511; P:ubiquitin-dependent protein catabolic process; IDA:RGD.
123A2VDP1    975   BRE1A_BOVIN E3 ubiquitin-protein ligase BRE1A...330.64     35     42     58GO:0005730; C:nucleolus; ISS:UniProtKB.::GO:0000151; C:ubiquitin ligase complex; ISS:UniProtKB.
GO:0042393; F:histone binding; ISS:UniProtKB.::GO:0002039; F:p53 binding; ISS:UniProtKB.::GO:0003713; F:transcription coactivator activity; ISS:UniProtKB.::GO:0031625; F:ubiquitin protein ligase binding; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0033523; P:histone H2B ubiquitination; ISS:UniProtKB.::GO:0010390; P:histone monoubiquitination; ISS:UniProtKB.::GO:0030336; P:negative regulation of cell migration; ISS:UniProtKB.::GO:0045893; P:positive regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0000209; P:protein polyubiquitination; ISS:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; ISS:UniProtKB.
124P34909    587   NOT4_YEAST General negative regulator of tran...720.66     35     32     49GO:0030015; C:CCR4-NOT core complex; IPI:SGD.::GO:0005737; C:cytoplasm; IDA:SGD.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.::GO:0043565; F:sequence-specific DNA binding; IDA:SGD.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:SGD.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0031087; P:deadenylation-independent decapping of nuclear-transcribed mRNA; IMP:SGD.::GO:0032968; P:positive regulation of transcription elongation from RNA polymerase II promoter; IDA:SGD.::GO:0000209; P:protein polyubiquitination; IDA:SGD.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
125Q640S6    477   TRI72_XENTR Tripartite motif-containing prote...320.67     35     44     50GO:0030659; C:cytoplasmic vesicle membrane; ISS:UniProtKB.::GO:0042383; C:sarcolemma; ISS:UniProtKB.
GO:0001786; F:phosphatidylserine binding; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006887; P:exocytosis; IEA:UniProtKB-KW.::GO:0007517; P:muscle organ development; ISS:UniProtKB.::GO:0003012; P:muscle system process; ISS:UniProtKB.::GO:0001778; P:plasma membrane repair; ISS:UniProtKB.::GO:0051260; P:protein homooligomerization; ISS:UniProtKB.
126Q5DTM8    973   BRE1A_MOUSE E3 ubiquitin-protein ligase BRE1A...330.67     35     42     58
GO:0008270; F:zinc ion binding; IEA:InterPro.
127Q4R7K7    1001   BRE1B_MACFA E3 ubiquitin-protein ligase BRE1B...480.68     35     40     52GO:0005634; C:nucleus; ISS:UniProtKB.::GO:0000151; C:ubiquitin ligase complex; ISS:UniProtKB.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0042803; F:protein homodimerization activity; ISS:UniProtKB.::GO:0031625; F:ubiquitin protein ligase binding; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0033523; P:histone H2B ubiquitination; ISS:UniProtKB.::GO:0010390; P:histone monoubiquitination; ISS:UniProtKB.
128Q5VTR2    975   BRE1A_HUMAN E3 ubiquitin-protein ligase BRE1A...330.68     35     42     58GO:0005730; C:nucleolus; IDA:UniProtKB.::GO:0000151; C:ubiquitin ligase complex; IDA:UniProtKB.
GO:0042393; F:histone binding; IDA:UniProtKB.::GO:0002039; F:p53 binding; IDA:UniProtKB.::GO:0003713; F:transcription coactivator activity; IDA:UniProtKB.::GO:0031625; F:ubiquitin protein ligase binding; IPI:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0033523; P:histone H2B ubiquitination; IDA:UniProtKB.::GO:0010390; P:histone monoubiquitination; IDA:UniProtKB.::GO:0030336; P:negative regulation of cell migration; IDA:UniProtKB.::GO:0045893; P:positive regulation of transcription, DNA-dependent; IMP:UniProtKB.::GO:0000209; P:protein polyubiquitination; IDA:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IMP:UniProtKB.
129Q4WDD7    725   BRE1_ASPFU E3 ubiquitin-protein ligase bre1 O...450.69     35     36     51GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.
130P53769    259   CWC24_YEAST Pre-mRNA-splicing factor CWC24 OS...370.7     34.7     30     54GO:0005684; C:U2-type spliceosomal complex; IDA:SGD.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0034247; P:snoRNA splicing; IMP:SGD.
131Q3U319    1001   BRE1B_MOUSE E3 ubiquitin-protein ligase BRE1B...480.71     35     40     52GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0008270; F:zinc ion binding; IEA:InterPro.
132Q28DS3    257   RN170_XENTR RING finger protein 170 OS=Xenopu...700.76     34.3     30     46GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0008270; F:zinc ion binding; IEA:InterPro.
133Q6CJM4    1114   RAD5_KLULA DNA repair protein RAD5 OS=1267 / ...540.77     35     30     44GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0004386; F:helicase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
134O75150    1001   BRE1B_HUMAN E3 ubiquitin-protein ligase BRE1B...480.78     35     40     52GO:0005737; C:cytoplasm; IDA:HPA.::GO:0005634; C:nucleus; IDA:UniProtKB.::GO:0005886; C:plasma membrane; IDA:HPA.::GO:0019717; C:synaptosome; ISS:UniProtKB.::GO:0000151; C:ubiquitin ligase complex; IDA:UniProtKB.
GO:0042803; F:protein homodimerization activity; IPI:UniProtKB.::GO:0031625; F:ubiquitin protein ligase binding; IPI:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0033523; P:histone H2B ubiquitination; IDA:UniProtKB.::GO:0010390; P:histone monoubiquitination; IDA:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; ISS:UniProtKB.
135Q9Y4K3    522   TRAF6_HUMAN TNF receptor-associated factor 6 ...770.79     34.7     30     47GO:0035631; C:CD40 receptor complex; ISS:BHF-UCL.::GO:0005938; C:cell cortex; IEA:UniProtKB-SubCell.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0010008; C:endosome membrane; TAS:Reactome.::GO:0009898; C:internal side of plasma membrane; ISS:BHF-UCL.::GO:0031965; C:nuclear membrane; IDA:HPA.::GO:0048471; C:perinuclear region of cytoplasm; IDA:BHF-UCL.
GO:0042826; F:histone deacetylase binding; IPI:UniProtKB.::GO:0031435; F:mitogen-activated protein kinase kinase kinase binding; IPI:UniProtKB.::GO:0043422; F:protein kinase B binding; IPI:UniProtKB.::GO:0047485; F:protein N-terminus binding; IPI:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0000187; P:activation of MAPK activity; TAS:Reactome.::GO:0007250; P:activation of NF-kappaB-inducing kinase activity; IMP:UniProtKB.::GO:0006916; P:anti-apoptosis; TAS:Reactome.::GO:0006915; P:apoptotic process; TAS:Reactome.::GO:0007249; P:I-kappaB kinase/NF-kappaB cascade; TAS:Reactome.::GO:0008624; P:induction of apoptosis by extracellular signals; TAS:Reactome.::GO:0045087; P:innate immune response; TAS:Reactome.::GO:0007254; P:JNK cascade; TAS:Reactome.::GO:0031293; P:membrane protein intracellular domain proteolysis; TAS:Reactome.::GO:0002755; P:MyD88-dependent toll-like receptor signaling pathway; TAS:Reactome.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IMP:UniProtKB.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0070423; P:nucleotide-binding oligomerization domain containing signaling pathway; TAS:Reactome.::GO:0001503; P:ossification; IEA:UniProtKB-KW.::GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB cascade; IDA:UniProtKB.::GO:0032743; P:positive regulation of interleukin-2 production; IMP:UniProtKB.::GO:0043507; P:positive regulation of JUN kinase activity; NAS:UniProtKB.::GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; IDA:UniProtKB.::GO:0045672; P:positive regulation of osteoclast differentiation; IDA:UniProtKB.::GO:0050870; P:positive regulation of T cell activation; IC:UniProtKB.::GO:0002726; P:positive regulation of T cell cytokine production; IMP:UniProtKB.::GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IDA:BHF-UCL.::GO:2000679; P:positive regulation of transcription regulatory region DNA binding; IDA:BHF-UCL.::GO:0051865; P:protein autoubiquitination; IDA:UniProtKB.::GO:0070534; P:protein K63-linked ubiquitination; IDA:UniProtKB.::GO:0070555; P:response to interleukin-1; IDA:UniProtKB.::GO:0050852; P:T cell receptor signaling pathway; IMP:UniProtKB.::GO:0008063; P:Toll signaling pathway; TAS:Reactome.::GO:0034130; P:toll-like receptor 1 signaling pathway; TAS:Reactome.::GO:0034134; P:toll-like receptor 2 signaling pathway; TAS:Reactome.::GO:0034138; P:toll-like receptor 3 signaling pathway; TAS:Reactome.::GO:0034142; P:toll-like receptor 4 signaling pathway; TAS:Reactome.::GO:0035666; P:TRIF-dependent toll-like receptor signaling pathway; TAS:Reactome.
136B6CJY4    522   TRAF6_CERAT TNF receptor-associated factor 6 ...770.79     34.7     30     47GO:0005938; C:cell cortex; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0070534; P:protein K63-linked ubiquitination; ISS:UniProtKB.::GO:0042981; P:regulation of apoptotic process; IEA:InterPro.::GO:0007165; P:signal transduction; IEA:InterPro.
137Q5RAU7    1001   BRE1B_PONAB E3 ubiquitin-protein ligase BRE1B...480.79     35     40     52GO:0005634; C:nucleus; ISS:UniProtKB.::GO:0000151; C:ubiquitin ligase complex; ISS:UniProtKB.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0042803; F:protein homodimerization activity; ISS:UniProtKB.::GO:0031625; F:ubiquitin protein ligase binding; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0033523; P:histone H2B ubiquitination; ISS:UniProtKB.::GO:0010390; P:histone monoubiquitination; ISS:UniProtKB.
138Q5ZLS3    984   BRE1A_CHICK E3 ubiquitin-protein ligase BRE1A...330.8     35     42     58GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.
139Q8LBL5    410   PRT1_ARATH E3 ubiquitin-protein ligase PRT1 O...960.81     34.7     29     47GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
140Q8V571    242   P28_MONPV E3 ubiquitin-protein ligase p28-lik...800.84     34.3     24     43GO:0030430; C:host cell cytoplasm; IEA:UniProtKB-SubCell.
GO:0016881; F:acid-amino acid ligase activity; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW.
141Q8C0E3    641   TRI47_MOUSE Tripartite motif-containing prote...270.9     34.7     48     56GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0008270; F:zinc ion binding; IEA:InterPro.
142Q9FPH0    376   XB34_ARATH Putative E3 ubiquitin-protein liga...740.98     34.3     32     46
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
143B6CJY5    522   TRAF6_MACMU TNF receptor-associated factor 6 ...770.99     34.7     30     47GO:0005938; C:cell cortex; IEA:UniProtKB-SubCell.
GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0070534; P:protein K63-linked ubiquitination; ISS:UniProtKB.::GO:0042981; P:regulation of apoptotic process; IEA:InterPro.
144P0CQ64    329   CWC24_CRYNJ Pre-mRNA-splicing factor CWC24 OS...411     34.3     34     46GO:0005681; C:spliceosomal complex; IEA:UniProtKB-KW.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
145P0CQ65    329   CWC24_CRYNB Pre-mRNA-splicing factor CWC24 OS...411     34.3     34     46GO:0005681; C:spliceosomal complex; IEA:UniProtKB-KW.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.::GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
146Q9SYU4    381   PEX10_ARATH Peroxisome biogenesis factor 10 O...471     34.3     32     47GO:0005829; C:cytosol; IDA:TAIR.::GO:0005779; C:integral to peroxisomal membrane; IEA:InterPro.
GO:0005515; F:protein binding; IPI:IntAct.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0010381; P:attachment of peroxisome to chloroplast; IMP:TAIR.::GO:0009793; P:embryo development ending in seed dormancy; IMP:TAIR.::GO:0006635; P:fatty acid beta-oxidation; IMP:TAIR.::GO:0009853; P:photorespiration; IMP:TAIR.::GO:0016558; P:protein import into peroxisome matrix; IMP:TAIR.
147Q8R0K2    507   TRI31_MOUSE E3 ubiquitin-protein ligase TRIM3...481.1     34.3     35     50GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
148Q24746    747   NEUR_DROVI Protein neuralized OS=Drosophila v...481.1     34.3     33     52GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; ISS:UniProtKB.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007498; P:mesoderm development; ISS:UniProtKB.::GO:0007422; P:peripheral nervous system development; ISS:UniProtKB.::GO:0016360; P:sensory organ precursor cell fate determination; ISS:UniProtKB.
149O14212    470   YDT7_SCHPO Uncharacterized RING finger protei...551.1     34.3     31     45GO:0005829; C:cytosol; IDA:PomBase.
GO:0008270; F:zinc ion binding; IEA:InterPro.
150P29503    754   NEUR_DROME Protein neuralized OS=Drosophila m...481.1     34.3     33     52GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; IDA:FlyBase.::GO:0005886; C:plasma membrane; IDA:FlyBase.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:FlyBase.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0008356; P:asymmetric cell division; TAS:FlyBase.::GO:0048854; P:brain morphogenesis; IMP:FlyBase.::GO:0048749; P:compound eye development; IMP:FlyBase.::GO:0007398; P:ectoderm development; TAS:FlyBase.::GO:0030718; P:germ-line stem cell maintenance; IMP:FlyBase.::GO:0007476; P:imaginal disc-derived wing morphogenesis; IMP:FlyBase.::GO:0002121; P:inter-male aggressive behavior; IMP:FlyBase.::GO:0031987; P:locomotion involved in locomotory behavior; IMP:FlyBase.::GO:0007498; P:mesoderm development; IMP:FlyBase.::GO:0042048; P:olfactory behavior; IMP:FlyBase.::GO:0030707; P:ovarian follicle cell development; TAS:FlyBase.::GO:0007422; P:peripheral nervous system development; IMP:FlyBase.::GO:0045747; P:positive regulation of Notch signaling pathway; TAS:FlyBase.::GO:0008104; P:protein localization; IMP:FlyBase.::GO:0045314; P:regulation of compound eye photoreceptor development; IMP:FlyBase.::GO:0016360; P:sensory organ precursor cell fate determination; IMP:FlyBase.::GO:0001964; P:startle response; IMP:FlyBase.
151Q6CTZ8    427   RAD18_KLULA Postreplication repair E3 ubiquit...361.2     34.3     33     56GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0003684; F:damaged DNA binding; IEA:InterPro.::GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006281; P:DNA repair; IEA:UniProtKB-KW.
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