Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YER114C
Length:
1040
Number of sequences:
5887
Description:
YER114C BOI2 SGDID:S000000916, Chr V from 393712-390590, Genome Release 64-1-1, reverse complement, Verified ORF, "Protein implicated in polar growth, functionally redundant with Boi1p; interacts with bud-emergence protein Bem1p; contains an SH3 (src homology 3) domain and a PH (pleckstrin homology) domain"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
1P39969    1040   BOI2_YEAST Protein BOI2 OS=Saccharomyces cere...10400     2132     100     100GO:0005935; C:cellular bud neck; IDA:SGD.::GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.
GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct.
GO:0007118; P:budding cell apical bud growth; IGI:SGD.::GO:0030010; P:establishment of cell polarity; TAS:SGD.::GO:0007266; P:Rho protein signal transduction; TAS:SGD.
2P38041    980   BOB1_YEAST Protein BOB1 OS=Saccharomyces cere...2251e-93     326     68     80GO:0005935; C:cellular bud neck; IDA:SGD.::GO:0043332; C:mating projection tip; IDA:SGD.
GO:0005543; F:phospholipid binding; IDA:SGD.::GO:0005515; F:protein binding; IPI:IntAct.
GO:0007118; P:budding cell apical bud growth; IGI:SGD.::GO:0030010; P:establishment of cell polarity; TAS:SGD.::GO:0007266; P:Rho protein signal transduction; TAS:SGD.
3O74653    871   POB1_SCHPO Protein pob1 OS=Schizosaccharomyce...2044e-32     139     41     59GO:0051285; C:cell cortex of cell tip; IDA:PomBase.::GO:0032153; C:cell division site; IDA:PomBase.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
GO:0005543; F:phospholipid binding; IEA:InterPro.
GO:0000920; P:cytokinetic cell separation; IMP:PomBase.::GO:0008360; P:regulation of cell shape; IMP:PomBase.
4B6RSP1    1197   PKHA7_DANRE Pleckstrin homology domain-contai...1100.000003     55.1     26     45GO:0005813; C:centrosome; ISS:UniProtKB.::GO:0005915; C:zonula adherens; ISS:UniProtKB.
GO:0070097; F:delta-catenin binding; ISS:UniProtKB.::GO:0005543; F:phospholipid binding; IEA:InterPro.
GO:0090136; P:epithelial cell-cell adhesion; ISS:UniProtKB.::GO:0045218; P:zonula adherens maintenance; ISS:UniProtKB.
5Q6IQ23    1121   PKHA7_HUMAN Pleckstrin homology domain-contai...1770.000004     54.7     25     45GO:0005813; C:centrosome; IDA:UniProtKB.::GO:0005634; C:nucleus; IDA:HPA.::GO:0005915; C:zonula adherens; IDA:UniProtKB.
GO:0070097; F:delta-catenin binding; IDA:UniProtKB.::GO:0005543; F:phospholipid binding; IEA:InterPro.
GO:0090136; P:epithelial cell-cell adhesion; IMP:UniProtKB.::GO:0045218; P:zonula adherens maintenance; IMP:UniProtKB.
6Q3UIL6    1118   PKHA7_MOUSE Pleckstrin homology domain-contai...1750.000006     54.3     25     46GO:0005813; C:centrosome; ISS:UniProtKB.::GO:0005915; C:zonula adherens; ISS:UniProtKB.
GO:0070097; F:delta-catenin binding; ISS:UniProtKB.::GO:0005543; F:phospholipid binding; IEA:InterPro.
GO:0090136; P:epithelial cell-cell adhesion; ISS:UniProtKB.::GO:0045218; P:zonula adherens maintenance; ISS:UniProtKB.
7Q8WWN9    437   ICEF1_HUMAN Interactor protein for cytohesin ...2050.000007     53.5     25     41GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0005344; F:oxygen transporter activity; NAS:UniProtKB.::GO:0004601; F:peroxidase activity; ISS:UniProtKB.::GO:0005543; F:phospholipid binding; IEA:InterPro.
GO:0006979; P:response to oxidative stress; ISS:UniProtKB.
8Q86IV4    458   Y4775_DICDI PH domain-containing protein DDB_...1200.00001     52.4     28     45
GO:0005543; F:phospholipid binding; IEA:InterPro.
9Q5U2Z7    748   RHG24_RAT Rho GTPase-activating protein 24 OS...1210.00003     51.6     23     47GO:0042995; C:cell projection; IEA:UniProtKB-SubCell.::GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell.
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.
GO:0001525; P:angiogenesis; IEA:UniProtKB-KW.::GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0007165; P:signal transduction; IEA:InterPro.
10P60669    779   PKHA4_RAT Pleckstrin homology domain-containi...1220.00005     50.8     28     44GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
GO:0005543; F:phospholipid binding; IEA:InterPro.
11Q8C4V1    747   RHG24_MOUSE Rho GTPase-activating protein 24 ...1130.00006     50.8     24     47GO:0042995; C:cell projection; IEA:UniProtKB-SubCell.::GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell.
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.
GO:0001525; P:angiogenesis; IEA:UniProtKB-KW.::GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0007165; P:signal transduction; IEA:InterPro.
12Q8VC98    588   PKHA4_MOUSE Pleckstrin homology domain-contai...1220.00006     50.8     27     44GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
GO:0005543; F:phospholipid binding; IEA:InterPro.
13Q69ZI1    892   SH3R1_MOUSE E3 ubiquitin-protein ligase SH3RF...550.94     37.4     33     55GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0030027; C:lamellipodium; IDA:MGI.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0005078; F:MAP-kinase scaffold activity; IDA:MGI.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0046328; P:regulation of JNK cascade; IDA:MGI.
14Q15438    398   CYH1_HUMAN Cytohesin-1 OS=Homo sapiens (Human...440.00008     50.1     48     57GO:0005737; C:cytoplasm; IDA:MGI.::GO:0005886; C:plasma membrane; IDA:UniProtKB.
GO:0005086; F:ARF guanyl-nucleotide exchange factor activity; IBA:RefGenome.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct.
GO:0032012; P:regulation of ARF protein signal transduction; IEA:InterPro.::GO:0030155; P:regulation of cell adhesion; IDA:MGI.::GO:0016192; P:vesicle-mediated transport; TAS:ProtInc.
15Q76MZ1    398   CYH1_CHLAE Cytohesin-1 OS=Chlorocebus aethiop...440.00008     50.1     48     57GO:0005622; C:intracellular; IEA:InterPro.
GO:0005086; F:ARF guanyl-nucleotide exchange factor activity; IEA:InterPro.::GO:0005543; F:phospholipid binding; IEA:InterPro.
GO:0032012; P:regulation of ARF protein signal transduction; IEA:InterPro.
16Q99418    400   CYH2_HUMAN Cytohesin-2 OS=Homo sapiens (Human...440.00008     49.7     48     57GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0005624; C:membrane fraction; TAS:ProtInc.::GO:0005886; C:plasma membrane; IDA:UniProtKB.
GO:0005086; F:ARF guanyl-nucleotide exchange factor activity; IBA:RefGenome.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:UniProtKB.
GO:0030036; P:actin cytoskeleton organization; TAS:ProtInc.::GO:0006897; P:endocytosis; TAS:ProtInc.::GO:0032012; P:regulation of ARF protein signal transduction; IEA:InterPro.::GO:0030155; P:regulation of cell adhesion; IBA:RefGenome.
17P63035    400   CYH2_RAT Cytohesin-2 OS=Rattus norvegicus (Ra...440.00009     49.7     48     57GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005886; C:plasma membrane; ISS:UniProtKB.
GO:0005086; F:ARF guanyl-nucleotide exchange factor activity; IBA:RefGenome.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:RGD.
GO:0016358; P:dendrite development; TAS:RGD.::GO:0032012; P:regulation of ARF protein signal transduction; IEA:InterPro.::GO:0030155; P:regulation of cell adhesion; IBA:RefGenome.
18P97694    398   CYH1_RAT Cytohesin-1 OS=Rattus norvegicus (Ra...440.00009     49.7     48     57GO:0005737; C:cytoplasm; IBA:RefGenome.::GO:0005886; C:plasma membrane; ISS:UniProtKB.
GO:0005086; F:ARF guanyl-nucleotide exchange factor activity; IBA:RefGenome.::GO:0005543; F:phospholipid binding; IEA:InterPro.
GO:0032012; P:regulation of ARF protein signal transduction; IEA:InterPro.::GO:0030155; P:regulation of cell adhesion; IBA:RefGenome.
19Q9QX11    398   CYH1_MOUSE Cytohesin-1 OS=Mus musculus (Mouse...440.00009     49.7     48     57GO:0005737; C:cytoplasm; IBA:RefGenome.::GO:0005923; C:tight junction; IDA:MGI.
GO:0005086; F:ARF guanyl-nucleotide exchange factor activity; IBA:RefGenome.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:MGI.
GO:0090162; P:establishment of epithelial cell polarity; IMP:MGI.::GO:0032012; P:regulation of ARF protein signal transduction; IEA:InterPro.::GO:0030155; P:regulation of cell adhesion; IBA:RefGenome.
20Q71F54    894   SH3R1_RAT E3 ubiquitin-protein ligase SH3RF1 ...561.3     36.6     32     54GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0030027; C:lamellipodium; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006917; P:induction of apoptosis; IMP:RGD.
21O43739    400   CYH3_HUMAN Cytohesin-3 OS=Homo sapiens (Human...440.0001     49.7     48     57GO:0005737; C:cytoplasm; IBA:RefGenome.::GO:0005624; C:membrane fraction; TAS:ProtInc.::GO:0005886; C:plasma membrane; IDA:UniProtKB.
GO:0005545; F:1-phosphatidylinositol binding; TAS:ProtInc.::GO:0005086; F:ARF guanyl-nucleotide exchange factor activity; IBA:RefGenome.::GO:0005220; F:inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity; TAS:ProtInc.
GO:0032012; P:regulation of ARF protein signal transduction; IEA:InterPro.::GO:0030155; P:regulation of cell adhesion; IBA:RefGenome.::GO:0016192; P:vesicle-mediated transport; TAS:ProtInc.
22P97696    400   CYH3_RAT Cytohesin-3 OS=Rattus norvegicus (Ra...440.0001     49.3     48     57GO:0005737; C:cytoplasm; IBA:RefGenome.::GO:0005886; C:plasma membrane; ISS:UniProtKB.
GO:0005086; F:ARF guanyl-nucleotide exchange factor activity; IBA:RefGenome.
GO:0032012; P:regulation of ARF protein signal transduction; IEA:InterPro.
23Q9HAU0    1116   PKHA5_HUMAN Pleckstrin homology domain-contai...1150.0001     50.1     27     43
GO:0005545; F:1-phosphatidylinositol binding; NAS:UniProtKB.::GO:0005515; F:protein binding; IPI:IntAct.
24Q9H4M7    779   PKHA4_HUMAN Pleckstrin homology domain-contai...1220.0001     49.7     27     44GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
GO:0005545; F:1-phosphatidylinositol binding; NAS:UniProtKB.
25Q5RBR0    888   SH3R1_PONAB E3 ubiquitin-protein ligase SH3RF...561.1     37     32     54GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0030027; C:lamellipodium; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
26A5D7F8    840   SH3R1_BOVIN E3 ubiquitin-protein ligase SH3RF...551.1     37     33     55GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0030027; C:lamellipodium; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
27Q8N264    748   RHG24_HUMAN Rho GTPase-activating protein 24 ...1210.0002     48.9     23     46GO:0042995; C:cell projection; IEA:UniProtKB-SubCell.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0005925; C:focal adhesion; IEA:UniProtKB-SubCell.
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct.
GO:0001525; P:angiogenesis; IEA:UniProtKB-KW.::GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.::GO:0007264; P:small GTPase mediated signal transduction; TAS:Reactome.
28Q7Z6J0    888   SH3R1_HUMAN E3 ubiquitin-protein ligase SH3RF...561.1     37     32     54GO:0005829; C:cytosol; IDA:UniProtKB.::GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0030027; C:lamellipodium; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0043066; P:negative regulation of apoptotic process; IMP:UniProtKB.::GO:0043154; P:negative regulation of cysteine-type endopeptidase activity involved in apoptotic process; IMP:UniProtKB.::GO:2001237; P:negative regulation of extrinsic apoptotic signaling pathway; IMP:UniProtKB.
29Q6NRD3    826   SH3R1_XENLA E3 ubiquitin-protein ligase SH3RF...580.71     37.7     33     53GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0030027; C:lamellipodium; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
30Q28E95    861   SH3R1_XENTR E3 ubiquitin-protein ligase SH3RF...580.36     38.5     33     53GO:0005794; C:Golgi apparatus; IEA:UniProtKB-SubCell.::GO:0030027; C:lamellipodium; IEA:UniProtKB-SubCell.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
31P63034    400   CYH2_MOUSE Cytohesin-2 OS=Mus musculus (Mouse...440.0005     47.4     45     55GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005886; C:plasma membrane; ISS:UniProtKB.
GO:0005086; F:ARF guanyl-nucleotide exchange factor activity; IBA:RefGenome.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct.
GO:0032012; P:regulation of ARF protein signal transduction; IEA:InterPro.::GO:0030155; P:regulation of cell adhesion; IBA:RefGenome.
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