UniProt_SwissProt BLAST: Single locus

Species:

Saccharomyces cerevisiae S288C

Locus:

YER110C

Length:

1113

Number of sequences:

5887

Description:

YER110C KAP123 SGDID:S000000912, Chr V from 382103-378762, Genome Release 64-1-1, reverse complement, Verified ORF, "Karyopherin beta, mediates nuclear import of ribosomal proteins prior to assembly into ribosomes and import of histones H3 and H4; localizes to the nuclear pore, nucleus, and cytoplasm; exhibits genetic interactions with RAI1"

rec.	Subject	Hit Length	Description	Align.Len	E value	Bit score	% ident.	% pos.	GO associations
1	P40069	1113	IMB4_YEAST Importin subunit beta-4 OS=Sacchar...	1113	0	2266	100	100	GO:0005737; C:cytoplasm; IDA:SGD.::GO:0005643; C:nuclear pore; IDA:SGD.
									GO:0008139; F:nuclear localization sequence binding; IDA:SGD.::GO:0008565; F:protein transporter activity; IMP:SGD.
									GO:0051028; P:mRNA transport; IEA:UniProtKB-KW.::GO:0006607; P:NLS-bearing substrate import into nucleus; IMP:SGD.::GO:2000220; P:regulation of pseudohyphal growth; IMP:SGD.::GO:0006610; P:ribosomal protein import into nucleus; IMP:SGD.
2	O60100	1067	IMB4_SCHPO Probable importin subunit beta-4 O...	1134	3e-167	529	31	53	GO:0005829; C:cytosol; IDA:PomBase.::GO:0005635; C:nuclear envelope; IDA:PomBase.
									GO:0005488; F:binding; IEA:InterPro.::GO:0008565; F:protein transporter activity; TAS:PomBase.
									GO:0006913; P:nucleocytoplasmic transport; TAS:PomBase.::GO:0006605; P:protein targeting; NAS:PomBase.
3	Q8TEX9	1081	IPO4_HUMAN Importin-4 OS=Homo sapiens (Human)...	1067	7e-44	177	23	44	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0005488; F:binding; IEA:InterPro.::GO:0008565; F:protein transporter activity; IEA:InterPro.
									GO:0006886; P:intracellular protein transport; IEA:InterPro.
4	Q8VI75	1082	IPO4_MOUSE Importin-4 OS=Mus musculus (Mouse)...	1077	2e-39	162	24	42	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0008565; F:protein transporter activity; IEA:InterPro.
									GO:0006886; P:intracellular protein transport; IEA:InterPro.
5	O00410	1097	IPO5_HUMAN Importin-5 OS=Homo sapiens (Human)...	1048	2e-35	150	22	42	GO:0005737; C:cytoplasm; TAS:ProtInc.::GO:0005643; C:nuclear pore; TAS:ProtInc.::GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
									GO:0005095; F:GTPase inhibitor activity; TAS:ProtInc.::GO:0008565; F:protein transporter activity; IEA:InterPro.::GO:0008536; F:Ran GTPase binding; TAS:ProtInc.
									GO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW.::GO:0006607; P:NLS-bearing substrate import into nucleus; TAS:ProtInc.::GO:0006610; P:ribosomal protein import into nucleus; IDA:UniProtKB.
6	Q54EW3	1067	IPO5_DICDI Probable importin-5 homolog OS=Dic...	674	6e-35	148	24	45	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0005488; F:binding; IEA:InterPro.
									GO:0015031; P:protein transport; IEA:UniProtKB-KW.
7	Q8BKC5	1097	IPO5_MOUSE Importin-5 OS=Mus musculus (Mouse)...	1043	4e-34	145	22	42	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0005515; F:protein binding; IPI:IntAct.::GO:0008565; F:protein transporter activity; IEA:InterPro.
8	Q8BIV3	1105	RNBP6_MOUSE Ran-binding protein 6 OS=Mus musc...	1082	2e-27	124	22	41	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0005488; F:binding; IEA:InterPro.
									GO:0015031; P:protein transport; IEA:UniProtKB-KW.
9	O60518	1105	RNBP6_HUMAN Ran-binding protein 6 OS=Homo sap...	1082	1e-26	121	22	40	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0005488; F:binding; IEA:InterPro.
									GO:0015031; P:protein transport; IEA:UniProtKB-KW.
10	O74476	1095	IMB3_SCHPO Importin subunit beta-3 OS=Schizos...	1015	4e-25	117	21	40	GO:0005829; C:cytosol; IDA:PomBase.::GO:0031965; C:nuclear membrane; IDA:PomBase.
									GO:0005525; F:GTP binding; NAS:PomBase.::GO:0008565; F:protein transporter activity; TAS:PomBase.
									GO:0006606; P:protein import into nucleus; IDA:PomBase.::GO:0007346; P:regulation of mitotic cell cycle; IMP:PomBase.
11	P32337	1089	IMB3_YEAST Importin subunit beta-3 OS=Sacchar...	1034	0.00000000000002	82.4	21	42	GO:0005737; C:cytoplasm; IDA:SGD.::GO:0005634; C:nucleus; IDA:SGD.
									GO:0008139; F:nuclear localization sequence binding; IDA:SGD.::GO:0008565; F:protein transporter activity; IMP:SGD.
									GO:0006406; P:mRNA export from nucleus; IGI:SGD.::GO:0006606; P:protein import into nucleus; IMP:SGD.::GO:0007088; P:regulation of mitosis; IMP:SGD.::GO:0060188; P:regulation of protein desumoylation; IMP:SGD.
12	P52296	875	IMB1_RAT Importin subunit beta-1 OS=Rattus no...	103	0.0003	48.5	33	50	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
13	Q9UI26	975	IPO11_HUMAN Importin-11 OS=Homo sapiens (Huma...	140	0.0004	48.1	26	51	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0005488; F:binding; IEA:InterPro.
14	Q8K2V6	975	IPO11_MOUSE Importin-11 OS=Mus musculus (Mous...	140	0.0005	48.1	25	52	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0005515; F:protein binding; IPI:MGI.::GO:0008565; F:protein transporter activity; IDA:MGI.
									GO:0006610; P:ribosomal protein import into nucleus; IDA:MGI.
15	Q14974	876	IMB1_HUMAN Importin subunit beta-1 OS=Homo sa...	104	0.002	45.8	33	50	GO:0005829; C:cytosol; TAS:Reactome.::GO:0031965; C:nuclear membrane; IDA:HPA.::GO:0005643; C:nuclear pore; TAS:ProtInc.::GO:0005654; C:nucleoplasm; TAS:Reactome.
									GO:0008139; F:nuclear localization sequence binding; TAS:ProtInc.::GO:0019904; F:protein domain specific binding; IPI:UniProtKB.::GO:0008270; F:zinc ion binding; TAS:ProtInc.
									GO:0019221; P:cytokine-mediated signaling pathway; TAS:Reactome.::GO:0006309; P:DNA fragmentation involved in apoptotic nuclear change; TAS:Reactome.::GO:0006607; P:NLS-bearing substrate import into nucleus; TAS:ProtInc.::GO:0000060; P:protein import into nucleus, translocation; TAS:ProtInc.::GO:0006610; P:ribosomal protein import into nucleus; IDA:UniProtKB.::GO:0046796; P:viral genome transport in host cell; TAS:Reactome.::GO:0019058; P:viral infectious cycle; TAS:Reactome.
16	P70168	876	IMB1_MOUSE Importin subunit beta-1 OS=Mus mus...	104	0.012	43.5	32	50	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0043234; C:protein complex; IDA:MGI.
									GO:0008565; F:protein transporter activity; IDA:MGI.
									GO:0006610; P:ribosomal protein import into nucleus; IDA:MGI.
17	P33892	2672	GCN1_YEAST Translational activator GCN1 OS=Sa...	119	0.058	41.6	29	46	GO:0022626; C:cytosolic ribosome; IDA:SGD.::GO:0005739; C:mitochondrion; IDA:SGD.
									GO:0005515; F:protein binding; IPI:IntAct.
									GO:0006448; P:regulation of translational elongation; IMP:SGD.
18	Q05AL1	673	ARMC8_DANRE Armadillo repeat-containing prote...	128	0.17	39.7	24	53
									GO:0005488; F:binding; IEA:InterPro.
19	Q68FK4	720	ARMC8_XENLA Armadillo repeat-containing prote...	117	0.44	38.5	27	52
									GO:0005488; F:binding; IEA:InterPro.
20	P30822	1084	XPO1_YEAST Exportin-1 OS=Saccharomyces cerevi...	140	0.82	37.4	24	44	GO:0000776; C:kinetochore; IDA:SGD.::GO:0005634; C:nucleus; IDA:SGD.::GO:0048471; C:perinuclear region of cytoplasm; IEA:UniProtKB-SubCell.::GO:0005816; C:spindle pole body; IDA:SGD.
									GO:0005488; F:binding; IEA:InterPro.::GO:0008565; F:protein transporter activity; IDA:SGD.
									GO:0006406; P:mRNA export from nucleus; IMP:SGD.::GO:0006611; P:protein export from nucleus; IMP:SGD.::GO:0034501; P:protein localization to kinetochore; IGI:SGD.::GO:0000055; P:ribosomal large subunit export from nucleus; IMP:SGD.
21	Q9Y4F4	1720	F179B_HUMAN Protein FAM179B OS=Homo sapiens (...	154	2.7	35.8	25	44
									GO:0005488; F:binding; IEA:InterPro.
22	P25997	1050	EF3_CANAL Elongation factor 3 OS=Candida albi...	182	3.5	35.4	24	49	GO:0009986; C:cell surface; IDA:CGD.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IDA:CGD.::GO:0030445; C:yeast-form cell wall; IDA:CGD.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016887; F:ATPase activity; IDA:CGD.::GO:0003924; F:GTPase activity; ISS:CGD.::GO:0003746; F:translation elongation factor activity; IGI:CGD.
23	Q5R6S3	673	ARMC8_PONAB Armadillo repeat-containing prote...	117	5.4	34.7	25	51
									GO:0005488; F:binding; IEA:InterPro.
24	Q8BFY9	898	TNPO1_MOUSE Transportin-1 OS=Mus musculus (Mo...	148	6.5	34.7	25	39	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0005488; F:binding; IEA:InterPro.::GO:0008565; F:protein transporter activity; IEA:InterPro.
									GO:0006886; P:intracellular protein transport; IEA:InterPro.
25	Q92973	898	TNPO1_HUMAN Transportin-1 OS=Homo sapiens (Hu...	148	6.6	34.7	25	39	GO:0005829; C:cytosol; TAS:Reactome.::GO:0005634; C:nucleus; TAS:ProtInc.
									GO:0008139; F:nuclear localization sequence binding; TAS:ProtInc.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0008565; F:protein transporter activity; IEA:InterPro.
									GO:0010467; P:gene expression; TAS:Reactome.::GO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW.::GO:0016071; P:mRNA metabolic process; TAS:Reactome.::GO:0000060; P:protein import into nucleus, translocation; TAS:ProtInc.
26	Q3SYU7	898	TNPO1_BOVIN Transportin-1 OS=Bos taurus (Bovi...	148	6.5	34.7	25	39	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0005488; F:binding; IEA:InterPro.::GO:0008565; F:protein transporter activity; IEA:InterPro.
									GO:0006886; P:intracellular protein transport; IEA:InterPro.
27	Q2KI54	673	ARMC8_BOVIN Armadillo repeat-containing prote...	117	6.6	34.7	25	51
									GO:0005488; F:binding; IEA:InterPro.
28	Q8IUR7	673	ARMC8_HUMAN Armadillo repeat-containing prote...	117	6.6	34.3	25	51
									GO:0005488; F:binding; IEA:InterPro.
29	Q55CQ7	931	TNPO_DICDI Transportin OS=Dictyostelium disco...	89	6.8	34.7	27	46	GO:0005829; C:cytosol; ISS:dictyBase.::GO:0005635; C:nuclear envelope; ISS:dictyBase.
									GO:0008139; F:nuclear localization sequence binding; ISS:dictyBase.::GO:0008565; F:protein transporter activity; IEA:InterPro.
									GO:0006606; P:protein import into nucleus; ISS:dictyBase.
30	P35169	2470	TOR1_YEAST Serine/threonine-protein kinase TO...	96	8	34.3	26	43	GO:0010008; C:endosome membrane; IDA:SGD.::GO:0031234; C:extrinsic to internal side of plasma membrane; IDA:SGD.::GO:0000329; C:fungal-type vacuole membrane; IDA:SGD.::GO:0000139; C:Golgi membrane; IDA:SGD.::GO:0005624; C:membrane fraction; IDA:SGD.::GO:0005634; C:nucleus; IDA:SGD.::GO:0031931; C:TORC1 complex; IPI:SGD.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
									GO:0031505; P:fungal-type cell wall organization; IMP:SGD.::GO:0000080; P:G1 phase of mitotic cell cycle; IMP:SGD.::GO:0007126; P:meiosis; IMP:SGD.::GO:0031930; P:mitochondria-nucleus signaling pathway; IMP:SGD.::GO:0010507; P:negative regulation of autophagy; IGI:SGD.::GO:0051726; P:regulation of cell cycle; IMP:SGD.::GO:0001558; P:regulation of cell growth; IMP:SGD.::GO:0006974; P:response to DNA damage stimulus; IMP:SGD.::GO:0042254; P:ribosome biogenesis; IMP:SGD.::GO:0031929; P:TOR signaling cascade; IMP:SGD.::GO:0042790; P:transcription of nuclear large rRNA transcript from RNA polymerase I promoter; IMP:SGD.
31	A6QQJ3	469	PERI_BOVIN Peripherin OS=Bos taurus (Bovine)....	104	8.4	33.9	33	48
									GO:0005198; F:structural molecule activity; IEA:InterPro.

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