Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YER100W
Length:
250
Number of sequences:
5887
Description:
YER100W UBC6 SGDID:S000000902, Chr V from 359562-360314, Genome Release 64-1-1, Verified ORF, "Ubiquitin-conjugating enzyme involved in ER-associated protein degradation; located at the cytosolic side of the ER membrane; tail region contains a transmembrane segment at the C-terminus; substrate of the ubiquitin-proteasome pathway"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
91Q6DG60    328   UBE2Z_DANRE Ubiquitin-conjugating enzyme E2 Z...1250.000000000000006     76.3     33     55GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004842; F:ubiquitin-protein ligase activity; IEA:EC.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
92P0C8G4    217   UBC_ASFP4 Ubiquitin-conjugating enzyme E2 OS=...1740.000000000000007     74.3     33     48
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004842; F:ubiquitin-protein ligase activity; IEA:EC.
93P35129    147   UBC2_CAEEL Ubiquitin-conjugating enzyme E2 2 ...1150.000000000000008     73.2     34     53
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0031625; F:ubiquitin protein ligase binding; IPI:WormBase.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:WormBase.
GO:0006915; P:apoptotic process; IMP:WormBase.::GO:0016477; P:cell migration; IMP:WormBase.::GO:0008340; P:determination of adult lifespan; IMP:WormBase.::GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0007281; P:germ cell development; IMP:WormBase.::GO:0008406; P:gonad development; IMP:WormBase.::GO:0040007; P:growth; IMP:WormBase.::GO:0040035; P:hermaphrodite genitalia development; IMP:WormBase.::GO:0007126; P:meiosis; IMP:WormBase.::GO:0002119; P:nematode larval development; IMP:WormBase.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IDA:WormBase.
94D3ZDK2    147   UB2D1_RAT Ubiquitin-conjugating enzyme E2 D1 ...1150.000000000000008     73.2     36     51GO:0005737; C:cytoplasm; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.
GO:0070936; P:protein K48-linked ubiquitination; ISS:UniProtKB.
95P61080    147   UB2D1_MOUSE Ubiquitin-conjugating enzyme E2 D...1150.000000000000008     73.2     36     51GO:0005737; C:cytoplasm; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:MGI.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.
GO:0031398; P:positive regulation of protein ubiquitination; ISS:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; ISS:UniProtKB.
96P51668    147   UB2D1_HUMAN Ubiquitin-conjugating enzyme E2 D...1150.000000000000008     73.2     36     51GO:0005829; C:cytosol; TAS:Reactome.::GO:0005654; C:nucleoplasm; TAS:Reactome.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.
GO:0031145; P:anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; TAS:Reactome.::GO:0030509; P:BMP signaling pathway; TAS:Reactome.::GO:0007094; P:mitotic cell cycle spindle assembly checkpoint; TAS:Reactome.::GO:0051436; P:negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.::GO:0051437; P:positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.::GO:0070936; P:protein K48-linked ubiquitination; IDA:UniProtKB.::GO:0007179; P:transforming growth factor beta receptor signaling pathway; TAS:Reactome.
97Q2TA10    147   UB2D1_BOVIN Ubiquitin-conjugating enzyme E2 D...1150.000000000000008     73.2     36     51GO:0005737; C:cytoplasm; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.
GO:0070936; P:protein K48-linked ubiquitination; ISS:UniProtKB.
98O13685    148   UBC13_SCHPO Ubiquitin-conjugating enzyme E2 1...1140.000000000000009     73.2     33     54GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0042803; F:protein homodimerization activity; IDA:PomBase.::GO:0004842; F:ubiquitin-protein ligase activity; IEA:EC.
GO:0071479; P:cellular response to ionizing radiation; IDA:PomBase.::GO:0006301; P:postreplication repair; IMP:PomBase.::GO:0070534; P:protein K63-linked ubiquitination; IDA:PomBase.
99Q9Y818    167   UBC15_SCHPO Ubiquitin-conjugating enzyme E2 1...1340.00000000000001     72.8     34     52GO:0005634; C:nucleus; ISS:PomBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004842; F:ubiquitin-protein ligase activity; IEA:EC.
GO:0030466; P:chromatin silencing at silent mating-type cassette; IMP:PomBase.
100Q66KB0    313   UBE2Z_XENTR Ubiquitin-conjugating enzyme E2 Z...1250.00000000000002     74.7     32     54GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004842; F:ubiquitin-protein ligase activity; IEA:EC.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
101Q8LGF7    157   PEX4_ARATH Protein PEROXIN-4 OS=Arabidopsis t...1240.00000000000002     72.4     31     53GO:0005778; C:peroxisomal membrane; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:TAIR.::GO:0004842; F:ubiquitin-protein ligase activity; IEA:EC.
GO:0006635; P:fatty acid beta-oxidation; IMP:TAIR.::GO:0016558; P:protein import into peroxisome matrix; IMP:TAIR.
102Q6PCF7    313   UBE2Z_XENLA Ubiquitin-conjugating enzyme E2 Z...1250.00000000000002     74.7     32     54GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004842; F:ubiquitin-protein ligase activity; IEA:EC.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
103P25869    213   UBC_ASFM2 Ubiquitin-conjugating enzyme E2 OS=...1170.00000000000002     73.2     35     53
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004842; F:ubiquitin-protein ligase activity; IEA:EC.
104Q94A97    153   UBC35_ARATH Ubiquitin-conjugating enzyme E2 3...1210.00000000000002     72     31     53GO:0031372; C:UBC13-MMS2 complex; IPI:TAIR.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:TAIR.
GO:0006301; P:postreplication repair; IGI:TAIR.::GO:0046686; P:response to cadmium ion; IEP:TAIR.::GO:0010039; P:response to iron ion; IMP:TAIR.::GO:0010053; P:root epidermal cell differentiation; IGI:TAIR.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IDA:TAIR.
105Q9EQX9    152   UBE2N_RAT Ubiquitin-conjugating enzyme E2 N O...1140.00000000000002     72     32     54GO:0035370; C:UBC13-UEV1A complex; ISS:UniProtKB.::GO:0000151; C:ubiquitin ligase complex; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.
GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0070534; P:protein K63-linked ubiquitination; ISS:UniProtKB.::GO:0006511; P:ubiquitin-dependent protein catabolic process; TAS:RGD.
106P35134    148   UBC11_ARATH Ubiquitin-conjugating enzyme E2 1...1330.00000000000002     71.6     32     49
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:TAIR.
GO:0006511; P:ubiquitin-dependent protein catabolic process; IDA:TAIR.
107Q4R4I1    152   UBE2N_MACFA Ubiquitin-conjugating enzyme E2 N...1140.00000000000002     72     32     54GO:0035370; C:UBC13-UEV1A complex; ISS:UniProtKB.::GO:0000151; C:ubiquitin ligase complex; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.
GO:0006281; P:DNA repair; IEA:UniProtKB-KW.::GO:0070534; P:protein K63-linked ubiquitination; ISS:UniProtKB.
108Q5R7J6    152   UBE2N_PONAB Ubiquitin-conjugating enzyme E2 N...1140.00000000000002     72     32     54GO:0035370; C:UBC13-UEV1A complex; ISS:UniProtKB.::GO:0000151; C:ubiquitin ligase complex; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.
GO:0070534; P:protein K63-linked ubiquitination; ISS:UniProtKB.
109P61089    152   UBE2N_MOUSE Ubiquitin-conjugating enzyme E2 N...1140.00000000000002     72     32     54GO:0005737; C:cytoplasm; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB.::GO:0031372; C:UBC13-MMS2 complex; ISS:HGNC.::GO:0035370; C:UBC13-UEV1A complex; ISS:UniProtKB.::GO:0000151; C:ubiquitin ligase complex; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0043130; F:ubiquitin binding; ISS:HGNC.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.
GO:0000729; P:DNA double-strand break processing; ISS:HGNC.::GO:0000724; P:double-strand break repair via homologous recombination; ISS:HGNC.::GO:0016574; P:histone ubiquitination; ISS:HGNC.::GO:0045739; P:positive regulation of DNA repair; ISS:HGNC.::GO:0031058; P:positive regulation of histone modification; ISS:HGNC.::GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB cascade; ISS:HGNC.::GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; ISS:HGNC.::GO:0051443; P:positive regulation of ubiquitin-protein ligase activity; ISS:HGNC.::GO:0006301; P:postreplication repair; ISS:HGNC.::GO:0070534; P:protein K63-linked ubiquitination; ISS:UniProtKB.::GO:0033182; P:regulation of histone ubiquitination; ISS:HGNC.::GO:0050852; P:T cell receptor signaling pathway; ISS:HGNC.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IDA:MGI.
110P61088    152   UBE2N_HUMAN Ubiquitin-conjugating enzyme E2 N...1140.00000000000002     72     32     54GO:0005829; C:cytosol; TAS:Reactome.::GO:0005634; C:nucleus; IDA:UniProtKB.::GO:0031372; C:UBC13-MMS2 complex; IDA:HGNC.::GO:0035370; C:UBC13-UEV1A complex; IDA:UniProtKB.::GO:0000151; C:ubiquitin ligase complex; IDA:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0043130; F:ubiquitin binding; IDA:HGNC.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.
GO:0019221; P:cytokine-mediated signaling pathway; TAS:Reactome.::GO:0000729; P:DNA double-strand break processing; IMP:HGNC.::GO:0000724; P:double-strand break repair via homologous recombination; IMP:HGNC.::GO:0016574; P:histone ubiquitination; IMP:HGNC.::GO:0045087; P:innate immune response; TAS:Reactome.::GO:0002755; P:MyD88-dependent toll-like receptor signaling pathway; TAS:Reactome.::GO:0070423; P:nucleotide-binding oligomerization domain containing signaling pathway; TAS:Reactome.::GO:0045739; P:positive regulation of DNA repair; IMP:HGNC.::GO:0031058; P:positive regulation of histone modification; IMP:HGNC.::GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB cascade; IMP:HGNC.::GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; IMP:UniProtKB.::GO:0051443; P:positive regulation of ubiquitin-protein ligase activity; IMP:HGNC.::GO:0006301; P:postreplication repair; IMP:HGNC.::GO:0070534; P:protein K63-linked ubiquitination; IDA:UniProtKB.::GO:0033182; P:regulation of histone ubiquitination; IMP:HGNC.::GO:0050852; P:T cell receptor signaling pathway; IMP:UniProtKB.::GO:0008063; P:Toll signaling pathway; TAS:Reactome.::GO:0034130; P:toll-like receptor 1 signaling pathway; TAS:Reactome.::GO:0034134; P:toll-like receptor 2 signaling pathway; TAS:Reactome.::GO:0034142; P:toll-like receptor 4 signaling pathway; TAS:Reactome.
111Q0P5K3    152   UBE2N_BOVIN Ubiquitin-conjugating enzyme E2 N...1140.00000000000002     72     32     54GO:0035370; C:UBC13-UEV1A complex; ISS:UniProtKB.::GO:0000151; C:ubiquitin ligase complex; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.
GO:0070534; P:protein K63-linked ubiquitination; ISS:UniProtKB.
112P70711    147   U2D2B_RAT Ubiquitin-conjugating enzyme E2 D2B...1150.00000000000003     71.6     33     53
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004842; F:ubiquitin-protein ligase activity; IEA:EC.
113Q6ZWY6    147   U2D2B_MOUSE Ubiquitin-conjugating enzyme E2 D...1150.00000000000003     71.6     33     53
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004842; F:ubiquitin-protein ligase activity; IEA:EC.
114Q9SLE4    148   UBC29_ARATH Ubiquitin-conjugating enzyme E2 2...1150.00000000000003     71.6     33     52
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:TAIR.
GO:0006511; P:ubiquitin-dependent protein catabolic process; IDA:TAIR.
115P0C8G5    221   UBC_ASFWA Ubiquitin-conjugating enzyme E2 OS=...1170.00000000000004     72.4     35     53
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004842; F:ubiquitin-protein ligase activity; IEA:EC.
116P51965    193   UB2E1_HUMAN Ubiquitin-conjugating enzyme E2 E...1270.00000000000004     72     34     50GO:0005829; C:cytosol; TAS:Reactome.::GO:0005654; C:nucleoplasm; TAS:Reactome.::GO:0000151; C:ubiquitin ligase complex; IDA:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0042296; F:ISG15 ligase activity; IDA:HGNC.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.
GO:0031145; P:anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; TAS:Reactome.::GO:0019221; P:cytokine-mediated signaling pathway; TAS:Reactome.::GO:0033523; P:histone H2B ubiquitination; IDA:UniProtKB.::GO:0010390; P:histone monoubiquitination; IDA:UniProtKB.::GO:0032020; P:ISG15-protein conjugation; IDA:HGNC.::GO:0007094; P:mitotic cell cycle spindle assembly checkpoint; TAS:Reactome.::GO:0051436; P:negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.::GO:0051437; P:positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.::GO:0070936; P:protein K48-linked ubiquitination; IDA:UniProtKB.
117P52482    193   UB2E1_MOUSE Ubiquitin-conjugating enzyme E2 E...1270.00000000000004     72     34     50GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.
GO:0070936; P:protein K48-linked ubiquitination; ISS:UniProtKB.
118A5PKP9    147   UB2D4_XENLA Ubiquitin-conjugating enzyme E2 D...1150.00000000000004     71.2     34     51
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0031435; F:mitogen-activated protein kinase kinase kinase binding; IPI:UniProtKB.::GO:0043130; F:ubiquitin binding; IDA:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.
GO:0039020; P:pronephric nephron tubule development; IMP:UniProtKB.
119Q7ZY08    192   UBE2T_XENLA Ubiquitin-conjugating enzyme E2 T...1170.00000000000004     71.6     32     54GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003682; F:chromatin binding; ISS:UniProtKB.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.
GO:0006281; P:DNA repair; ISS:UniProtKB.::GO:0051865; P:protein autoubiquitination; ISS:UniProtKB.::GO:0006513; P:protein monoubiquitination; ISS:UniProtKB.
120Q9FZ48    153   UBC36_ARATH Ubiquitin-conjugating enzyme E2 3...1210.00000000000009     70.5     31     53GO:0005829; C:cytosol; IDA:TAIR.::GO:0005886; C:plasma membrane; IDA:TAIR.::GO:0031372; C:UBC13-MMS2 complex; IPI:TAIR.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:TAIR.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:TAIR.
GO:0010039; P:response to iron ion; IMP:TAIR.::GO:0010053; P:root epidermal cell differentiation; IGI:TAIR.::GO:0006511; P:ubiquitin-dependent protein catabolic process; IDA:TAIR.
121Q9C8X7    154   UBC31_ARATH Probable ubiquitin-conjugating en...1080.0000000000001     70.1     33     55GO:0005773; C:vacuole; IDA:TAIR.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004842; F:ubiquitin-protein ligase activity; IEA:EC.
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