UniProt_SwissProt BLAST: Single locus

Species:

Saccharomyces cerevisiae S288C

Locus:

YER100W

Length:

250

Number of sequences:

5887

Description:

YER100W UBC6 SGDID:S000000902, Chr V from 359562-360314, Genome Release 64-1-1, Verified ORF, "Ubiquitin-conjugating enzyme involved in ER-associated protein degradation; located at the cytosolic side of the ER membrane; tail region contains a transmembrane segment at the C-terminus; substrate of the ubiquitin-proteasome pathway"

rec.	Subject	Hit Length	Description	Align.Len	E value	Bit score	% ident.	% pos.	GO associations
301	O74983	139	MMS2_SCHPO Ubiquitin-conjugating enzyme spm2 ...	119	2.1	32.3	23	41	GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.
									GO:0016881; F:acid-amino acid ligase activity; IEA:InterPro.::GO:0042803; F:protein homodimerization activity; IGI:PomBase.
									GO:0071479; P:cellular response to ionizing radiation; IDA:PomBase.::GO:0006301; P:postreplication repair; IMP:PomBase.::GO:0070534; P:protein K63-linked ubiquitination; IDA:PomBase.
302	Q13404	147	UB2V1_HUMAN Ubiquitin-conjugating enzyme E2 v...	100	2.6	32	27	37	GO:0005829; C:cytosol; TAS:Reactome.::GO:0005634; C:nucleus; TAS:UniProtKB.::GO:0035370; C:UBC13-UEV1A complex; IDA:UniProtKB.::GO:0000151; C:ubiquitin ligase complex; IDA:UniProtKB.
									GO:0016881; F:acid-amino acid ligase activity; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct.
									GO:0030154; P:cell differentiation; NAS:UniProtKB.::GO:0045087; P:innate immune response; TAS:Reactome.::GO:0002755; P:MyD88-dependent toll-like receptor signaling pathway; TAS:Reactome.::GO:0070423; P:nucleotide-binding oligomerization domain containing signaling pathway; TAS:Reactome.::GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB cascade; IMP:HGNC.::GO:0051092; P:positive regulation of NF-kappaB transcription factor activity; IMP:HGNC.::GO:0045893; P:positive regulation of transcription, DNA-dependent; TAS:UniProtKB.::GO:0070534; P:protein K63-linked ubiquitination; IDA:UniProtKB.::GO:0006282; P:regulation of DNA repair; TAS:ProtInc.::GO:0050852; P:T cell receptor signaling pathway; TAS:Reactome.::GO:0008063; P:Toll signaling pathway; TAS:Reactome.::GO:0034130; P:toll-like receptor 1 signaling pathway; TAS:Reactome.::GO:0034134; P:toll-like receptor 2 signaling pathway; TAS:Reactome.::GO:0034142; P:toll-like receptor 4 signaling pathway; TAS:Reactome.
303	Q3SZ52	147	UB2V1_BOVIN Ubiquitin-conjugating enzyme E2 v...	100	2.6	32	27	37	GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0035370; C:UBC13-UEV1A complex; ISS:UniProtKB.::GO:0000151; C:ubiquitin ligase complex; ISS:UniProtKB.
									GO:0016881; F:acid-amino acid ligase activity; IEA:InterPro.
									GO:0070534; P:protein K63-linked ubiquitination; ISS:UniProtKB.
304	Q90879	145	UB2V1_CHICK Ubiquitin-conjugating enzyme E2 v...	100	2.7	32	27	37	GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0016881; F:acid-amino acid ligase activity; IEA:InterPro.
									GO:0034138; P:toll-like receptor 3 signaling pathway; TAS:Reactome.
305	Q10024	937	DGK5_CAEEL Putative diacylglycerol kinase K06...	67	3.4	32.7	33	49
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004143; F:diacylglycerol kinase activity; IEA:EC.
									GO:0007205; P:activation of protein kinase C activity by G-protein coupled receptor protein signaling pathway; IEA:InterPro.::GO:0035556; P:intracellular signal transduction; IEA:InterPro.
306	Q5R6C9	145	UB2V2_PONAB Ubiquitin-conjugating enzyme E2 v...	88	3.6	31.6	25	39
									GO:0016881; F:acid-amino acid ligase activity; IEA:InterPro.
307	Q15819	145	UB2V2_HUMAN Ubiquitin-conjugating enzyme E2 v...	88	3.6	31.6	25	39	GO:0005737; C:cytoplasm; TAS:HGNC.::GO:0005634; C:nucleus; IDA:HGNC.::GO:0031372; C:UBC13-MMS2 complex; IDA:HGNC.
									GO:0016881; F:acid-amino acid ligase activity; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct.
									GO:0008283; P:cell proliferation; TAS:ProtInc.::GO:0000729; P:DNA double-strand break processing; IMP:HGNC.::GO:0000209; P:protein polyubiquitination; TAS:ProtInc.::GO:0006282; P:regulation of DNA repair; TAS:ProtInc.
308	Q3SZ43	145	UB2V2_BOVIN Ubiquitin-conjugating enzyme E2 v...	88	3.6	31.6	25	39
									GO:0016881; F:acid-amino acid ligase activity; IEA:InterPro.
309	Q7ZYP0	145	UB2V2_XENLA Ubiquitin-conjugating enzyme E2 v...	93	3.6	31.6	28	38
									GO:0016881; F:acid-amino acid ligase activity; IEA:InterPro.
310	Q93YP0	158	UEV1A_ARATH Ubiquitin-conjugating enzyme E2 v...	39	4.1	31.6	36	49	GO:0031372; C:UBC13-MMS2 complex; IPI:TAIR.
									GO:0016881; F:acid-amino acid ligase activity; IEA:InterPro.::GO:0005515; F:protein binding; IPI:TAIR.
									GO:0006301; P:postreplication repair; IGI:TAIR.
311	Q6UXU4	331	GSG1L_HUMAN Germ cell-specific gene 1-like pr...	87	5.2	32	26	39	GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
312	A5WDY5	213	COQ7_PSYWF 2-nonaprenyl-3-methyl-6-methoxy-1,...	85	5.6	31.6	28	46	GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
									GO:0004497; F:monooxygenase activity; IEA:UniProtKB-KW.::GO:0046914; F:transition metal ion binding; IEA:InterPro.
									GO:0019538; P:protein metabolic process; IEA:InterPro.::GO:0006744; P:ubiquinone biosynthetic process; IEA:UniProtKB-KW.
313	Q5F3Z3	144	UB2V2_CHICK Ubiquitin-conjugating enzyme E2 v...	88	7.7	30.4	25	38
									GO:0016881; F:acid-amino acid ligase activity; IEA:InterPro.
314	Q5NCY0	1641	KDM6B_MOUSE Lysine-specific demethylase 6B OS...	67	9.5	31.2	34	43	GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
									GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0016702; F:oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen; IEA:UniProtKB-KW.::GO:0043565; F:sequence-specific DNA binding; IDA:MGI.
									GO:0016577; P:histone demethylation; IMP:MGI.::GO:0006954; P:inflammatory response; IEA:UniProtKB-KW.::GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IDA:MGI.

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