UniProt_SwissProt BLAST: Single locus

Species:

Saccharomyces cerevisiae S288C

Locus:

YER099C

Length:

318

Number of sequences:

5887

Description:

YER099C PRS2 SGDID:S000000901, Chr V from 359061-358105, Genome Release 64-1-1, reverse complement, Verified ORF, "5-phospho-ribosyl-1(alpha)-pyrophosphate synthetase, synthesizes PRPP, which is required for nucleotide, histidine, and tryptophan biosynthesis; one of five related enzymes, which are active as heteromultimeric complexes"

rec.	Subject	Hit Length	Description	Align.Len	E value	Bit score	% ident.	% pos.	GO associations
1	P38620	318	KPR2_YEAST Ribose-phosphate pyrophosphokinase...	318	0	652	100	100	GO:0005737; C:cytoplasm; IDA:SGD.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016301; F:kinase activity; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004749; F:ribose phosphate diphosphokinase activity; IEA:EC.
									GO:0006015; P:5-phosphoribose 1-diphosphate biosynthetic process; IMP:SGD.::GO:0031505; P:fungal-type cell wall organization; IPI:SGD.::GO:0009116; P:nucleoside metabolic process; IEA:InterPro.::GO:0009156; P:ribonucleoside monophosphate biosynthetic process; IEA:InterPro.
2	P38063	326	KPR4_YEAST Ribose-phosphate pyrophosphokinase...	318	0	598	90	95	GO:0005737; C:cytoplasm; IDA:SGD.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016301; F:kinase activity; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0004749; F:ribose phosphate diphosphokinase activity; IEA:EC.
									GO:0006015; P:5-phosphoribose 1-diphosphate biosynthetic process; IMP:SGD.::GO:0031505; P:fungal-type cell wall organization; IPI:SGD.::GO:0009116; P:nucleoside metabolic process; IEA:InterPro.::GO:0009156; P:ribonucleoside monophosphate biosynthetic process; IEA:InterPro.
3	O94413	321	KPR2_SCHPO Ribose-phosphate pyrophosphokinase...	322	2e-151	434	66	81	GO:0005829; C:cytosol; IDA:PomBase.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016301; F:kinase activity; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0004749; F:ribose phosphate diphosphokinase activity; ISS:PomBase.
									GO:0009116; P:nucleoside metabolic process; IEA:InterPro.::GO:0006163; P:purine nucleotide metabolic process; NAS:PomBase.::GO:0009156; P:ribonucleoside monophosphate biosynthetic process; IEA:InterPro.
4	P46585	321	KPR1_CANAX Ribose-phosphate pyrophosphokinase...	321	7e-150	431	65	81
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016301; F:kinase activity; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0004749; F:ribose phosphate diphosphokinase activity; IEA:EC.
									GO:0009116; P:nucleoside metabolic process; IEA:InterPro.::GO:0009156; P:ribonucleoside monophosphate biosynthetic process; IEA:InterPro.
5	P38689	320	KPR3_YEAST Ribose-phosphate pyrophosphokinase...	321	5e-146	421	63	81	GO:0005737; C:cytoplasm; IDA:SGD.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016301; F:kinase activity; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004749; F:ribose phosphate diphosphokinase activity; IEA:EC.
									GO:0006015; P:5-phosphoribose 1-diphosphate biosynthetic process; IMP:SGD.::GO:0031505; P:fungal-type cell wall organization; IPI:SGD.::GO:0009116; P:nucleoside metabolic process; IEA:InterPro.::GO:0008361; P:regulation of cell size; IMP:SGD.::GO:0009156; P:ribonucleoside monophosphate biosynthetic process; IEA:InterPro.
6	Q5XGI0	318	PRPS2_XENTR Ribose-phosphate pyrophosphokinas...	318	3e-138	401	62	78
									GO:0005524; F:ATP binding; ISS:UniProtKB.::GO:0016301; F:kinase activity; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0042803; F:protein homodimerization activity; ISS:UniProtKB.::GO:0004749; F:ribose phosphate diphosphokinase activity; ISS:UniProtKB.
									GO:0009116; P:nucleoside metabolic process; IEA:InterPro.::GO:0009156; P:ribonucleoside monophosphate biosynthetic process; IEA:InterPro.
7	P09330	318	PRPS2_RAT Ribose-phosphate pyrophosphokinase ...	318	4e-138	400	62	78	GO:0002189; C:ribose phosphate diphosphokinase complex; IDA:RGD.::GO:0005625; C:soluble fraction; IDA:RGD.
									GO:0043531; F:ADP binding; IDA:RGD.::GO:0016208; F:AMP binding; IDA:RGD.::GO:0005524; F:ATP binding; ISS:UniProtKB.::GO:0030246; F:carbohydrate binding; IDA:RGD.::GO:0019003; F:GDP binding; IDA:RGD.::GO:0016301; F:kinase activity; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IDA:RGD.::GO:0042803; F:protein homodimerization activity; ISS:UniProtKB.::GO:0004749; F:ribose phosphate diphosphokinase activity; ISS:UniProtKB.
									GO:0006015; P:5-phosphoribose 1-diphosphate biosynthetic process; IDA:RGD.::GO:0006167; P:AMP biosynthetic process; IDA:RGD.::GO:0009116; P:nucleoside metabolic process; IEA:InterPro.::GO:0031100; P:organ regeneration; IEP:RGD.
8	Q7ZXC9	318	PRPS2_XENLA Ribose-phosphate pyrophosphokinas...	318	7e-138	400	62	78
									GO:0005524; F:ATP binding; ISS:UniProtKB.::GO:0016301; F:kinase activity; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0042803; F:protein homodimerization activity; ISS:UniProtKB.::GO:0004749; F:ribose phosphate diphosphokinase activity; ISS:UniProtKB.
									GO:0009116; P:nucleoside metabolic process; IEA:InterPro.::GO:0009156; P:ribonucleoside monophosphate biosynthetic process; IEA:InterPro.
9	Q5R8F8	318	PRPS2_PONAB Ribose-phosphate pyrophosphokinas...	318	2e-137	399	62	78
									GO:0005524; F:ATP binding; ISS:UniProtKB.::GO:0016301; F:kinase activity; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0042803; F:protein homodimerization activity; ISS:UniProtKB.::GO:0004749; F:ribose phosphate diphosphokinase activity; ISS:UniProtKB.
									GO:0009116; P:nucleoside metabolic process; IEA:InterPro.::GO:0009156; P:ribonucleoside monophosphate biosynthetic process; IEA:InterPro.
10	Q4R4R7	318	PRPS2_MACFA Ribose-phosphate pyrophosphokinas...	318	2e-137	399	62	78
									GO:0005524; F:ATP binding; ISS:UniProtKB.::GO:0016301; F:kinase activity; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0042803; F:protein homodimerization activity; ISS:UniProtKB.::GO:0004749; F:ribose phosphate diphosphokinase activity; ISS:UniProtKB.
									GO:0009116; P:nucleoside metabolic process; IEA:InterPro.::GO:0009156; P:ribonucleoside monophosphate biosynthetic process; IEA:InterPro.
11	P11908	318	PRPS2_HUMAN Ribose-phosphate pyrophosphokinas...	318	2e-137	399	62	78
									GO:0005524; F:ATP binding; ISS:UniProtKB.::GO:0016301; F:kinase activity; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0042803; F:protein homodimerization activity; ISS:UniProtKB.::GO:0004749; F:ribose phosphate diphosphokinase activity; ISS:UniProtKB.
									GO:0009116; P:nucleoside metabolic process; IEA:InterPro.::GO:0009156; P:ribonucleoside monophosphate biosynthetic process; IEA:InterPro.
12	Q9CS42	318	PRPS2_MOUSE Ribose-phosphate pyrophosphokinas...	318	2e-137	399	62	78
									GO:0005524; F:ATP binding; ISS:UniProtKB.::GO:0016301; F:kinase activity; IEA:UniProtKB-KW.::GO:0042803; F:protein homodimerization activity; ISS:UniProtKB.::GO:0004749; F:ribose phosphate diphosphokinase activity; ISS:UniProtKB.
									GO:0009116; P:nucleoside metabolic process; IEA:InterPro.
13	P60892	318	PRPS1_RAT Ribose-phosphate pyrophosphokinase ...	318	1e-136	397	61	78	GO:0002189; C:ribose phosphate diphosphokinase complex; IDA:RGD.::GO:0005625; C:soluble fraction; IDA:RGD.
									GO:0043531; F:ADP binding; IDA:RGD.::GO:0016208; F:AMP binding; IDA:RGD.::GO:0005524; F:ATP binding; ISS:UniProtKB.::GO:0030246; F:carbohydrate binding; IDA:RGD.::GO:0019003; F:GDP binding; IDA:RGD.::GO:0016301; F:kinase activity; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IDA:RGD.::GO:0042803; F:protein homodimerization activity; ISS:UniProtKB.::GO:0004749; F:ribose phosphate diphosphokinase activity; ISS:UniProtKB.
									GO:0006015; P:5-phosphoribose 1-diphosphate biosynthetic process; IDA:RGD.::GO:0006167; P:AMP biosynthetic process; IDA:RGD.::GO:0009116; P:nucleoside metabolic process; IEA:InterPro.::GO:0031100; P:organ regeneration; IEP:RGD.
14	Q5RFJ7	318	PRPS1_PONAB Ribose-phosphate pyrophosphokinas...	318	1e-136	397	61	78
									GO:0005524; F:ATP binding; ISS:UniProtKB.::GO:0016301; F:kinase activity; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0042803; F:protein homodimerization activity; ISS:UniProtKB.::GO:0004749; F:ribose phosphate diphosphokinase activity; ISS:UniProtKB.
									GO:0009116; P:nucleoside metabolic process; IEA:InterPro.::GO:0009156; P:ribonucleoside monophosphate biosynthetic process; IEA:InterPro.
15	Q9D7G0	318	PRPS1_MOUSE Ribose-phosphate pyrophosphokinas...	318	1e-136	397	61	78
									GO:0005524; F:ATP binding; ISS:UniProtKB.::GO:0016301; F:kinase activity; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0042803; F:protein homodimerization activity; ISS:UniProtKB.::GO:0004749; F:ribose phosphate diphosphokinase activity; ISS:UniProtKB.
									GO:0009116; P:nucleoside metabolic process; IEA:InterPro.::GO:0009156; P:ribonucleoside monophosphate biosynthetic process; IEA:InterPro.
16	P60891	318	PRPS1_HUMAN Ribose-phosphate pyrophosphokinas...	318	1e-136	397	61	78	GO:0005829; C:cytosol; TAS:Reactome.
									GO:0005524; F:ATP binding; IDA:UniProtKB.::GO:0016301; F:kinase activity; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0042803; F:protein homodimerization activity; IPI:UniProtKB.::GO:0004749; F:ribose phosphate diphosphokinase activity; IDA:UniProtKB.
									GO:0006015; P:5-phosphoribose 1-diphosphate biosynthetic process; TAS:Reactome.::GO:0046101; P:hypoxanthine biosynthetic process; IMP:UniProtKB.::GO:0007399; P:nervous system development; IMP:UniProtKB.::GO:0009116; P:nucleoside metabolic process; IEA:InterPro.::GO:0006164; P:purine nucleotide biosynthetic process; IMP:UniProtKB.::GO:0006221; P:pyrimidine nucleotide biosynthetic process; NAS:UniProtKB.::GO:0009156; P:ribonucleoside monophosphate biosynthetic process; IEA:InterPro.::GO:0034418; P:urate biosynthetic process; IMP:UniProtKB.
17	Q2HJ58	318	PRPS1_BOVIN Ribose-phosphate pyrophosphokinas...	318	1e-136	397	61	78
									GO:0005524; F:ATP binding; ISS:UniProtKB.::GO:0016301; F:kinase activity; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0042803; F:protein homodimerization activity; ISS:UniProtKB.::GO:0004749; F:ribose phosphate diphosphokinase activity; ISS:UniProtKB.
									GO:0009116; P:nucleoside metabolic process; IEA:InterPro.::GO:0009156; P:ribonucleoside monophosphate biosynthetic process; IEA:InterPro.
18	Q4R4U3	318	PRPS1_MACFA Ribose-phosphate pyrophosphokinas...	318	6e-136	395	61	77
									GO:0005524; F:ATP binding; ISS:UniProtKB.::GO:0016301; F:kinase activity; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0042803; F:protein homodimerization activity; ISS:UniProtKB.::GO:0004749; F:ribose phosphate diphosphokinase activity; ISS:UniProtKB.
									GO:0009116; P:nucleoside metabolic process; IEA:InterPro.::GO:0009156; P:ribonucleoside monophosphate biosynthetic process; IEA:InterPro.
19	Q5ZI49	325	PRPS2_CHICK Ribose-phosphate pyrophosphokinas...	325	2e-133	389	60	76
									GO:0005524; F:ATP binding; ISS:UniProtKB.::GO:0016301; F:kinase activity; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0042803; F:protein homodimerization activity; ISS:UniProtKB.::GO:0004749; F:ribose phosphate diphosphokinase activity; ISS:UniProtKB.
									GO:0009116; P:nucleoside metabolic process; IEA:InterPro.::GO:0009156; P:ribonucleoside monophosphate biosynthetic process; IEA:InterPro.
20	P21108	318	PRPS3_HUMAN Ribose-phosphate pyrophosphokinas...	318	5e-131	382	60	76
									GO:0005524; F:ATP binding; ISS:UniProtKB.::GO:0016301; F:kinase activity; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0042803; F:protein homodimerization activity; ISS:UniProtKB.::GO:0004749; F:ribose phosphate diphosphokinase activity; ISS:UniProtKB.
									GO:0009116; P:nucleoside metabolic process; IEA:InterPro.::GO:0009156; P:ribonucleoside monophosphate biosynthetic process; NAS:UniProtKB.
21	Q54PA9	317	PRPSA_DICDI Ribose-phosphate pyrophosphokinas...	314	1e-119	353	59	73	GO:0045335; C:phagocytic vesicle; IDA:dictyBase.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016301; F:kinase activity; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0004749; F:ribose phosphate diphosphokinase activity; IEA:EC.
									GO:0000105; P:histidine biosynthetic process; ISS:dictyBase.::GO:0009116; P:nucleoside metabolic process; IEA:InterPro.::GO:0009617; P:response to bacterium; IEP:dictyBase.::GO:0009156; P:ribonucleoside monophosphate biosynthetic process; IEA:InterPro.::GO:0000162; P:tryptophan biosynthetic process; ISS:dictyBase.
22	Q97E93	319	KPRS_CLOAB Ribose-phosphate pyrophosphokinase...	312	4e-94	288	49	67	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016301; F:kinase activity; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0004749; F:ribose phosphate diphosphokinase activity; IEA:EC.
									GO:0009116; P:nucleoside metabolic process; IEA:InterPro.::GO:0009156; P:ribonucleoside monophosphate biosynthetic process; IEA:InterPro.
23	Q8R753	316	KPRS_THETN Ribose-phosphate pyrophosphokinase...	314	7e-93	285	48	66	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016301; F:kinase activity; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0004749; F:ribose phosphate diphosphokinase activity; IEA:EC.
									GO:0009116; P:nucleoside metabolic process; IEA:InterPro.::GO:0009156; P:ribonucleoside monophosphate biosynthetic process; IEA:InterPro.
24	Q7M8J0	309	KPRS_WOLSU Ribose-phosphate pyrophosphokinase...	307	3e-91	281	47	64	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016301; F:kinase activity; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0004749; F:ribose phosphate diphosphokinase activity; IEA:EC.
									GO:0009116; P:nucleoside metabolic process; IEA:InterPro.::GO:0009156; P:ribonucleoside monophosphate biosynthetic process; IEA:InterPro.
25	Q89DJ1	317	KPRS_BRAJA Ribose-phosphate pyrophosphokinase...	315	3e-91	281	46	66	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016301; F:kinase activity; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0004749; F:ribose phosphate diphosphokinase activity; IEA:EC.
									GO:0009116; P:nucleoside metabolic process; IEA:InterPro.::GO:0009156; P:ribonucleoside monophosphate biosynthetic process; IEA:InterPro.
26	Q9PP15	309	KPRS_CAMJE Ribose-phosphate pyrophosphokinase...	307	1e-90	280	47	66	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016301; F:kinase activity; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0004749; F:ribose phosphate diphosphokinase activity; IEA:EC.
									GO:0009116; P:nucleoside metabolic process; IEA:InterPro.::GO:0009156; P:ribonucleoside monophosphate biosynthetic process; IEA:InterPro.
27	Q9CP22	315	KPRS_PASMU Ribose-phosphate pyrophosphokinase...	314	2e-90	279	47	66	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016301; F:kinase activity; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0004749; F:ribose phosphate diphosphokinase activity; IEA:EC.
									GO:0009116; P:nucleoside metabolic process; IEA:InterPro.::GO:0009156; P:ribonucleoside monophosphate biosynthetic process; IEA:InterPro.
28	Q7VL55	316	KPRS_HAEDU Ribose-phosphate pyrophosphokinase...	313	3e-90	278	47	66	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016301; F:kinase activity; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0004749; F:ribose phosphate diphosphokinase activity; IEA:EC.
									GO:0009116; P:nucleoside metabolic process; IEA:InterPro.::GO:0009156; P:ribonucleoside monophosphate biosynthetic process; IEA:InterPro.
29	P87171	341	KPR5_SCHPO Ribose-phosphate pyrophosphokinase...	337	3e-90	279	45	64	GO:0005737; C:cytoplasm; ISS:PomBase.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016301; F:kinase activity; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0004749; F:ribose phosphate diphosphokinase activity; ISS:PomBase.
									GO:0006015; P:5-phosphoribose 1-diphosphate biosynthetic process; ISS:PomBase.::GO:0009116; P:nucleoside metabolic process; IEA:InterPro.::GO:0006163; P:purine nucleotide metabolic process; NAS:PomBase.::GO:0009156; P:ribonucleoside monophosphate biosynthetic process; IEA:InterPro.
30	P44328	315	KPRS_HAEIN Ribose-phosphate pyrophosphokinase...	313	8e-90	277	47	66	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016301; F:kinase activity; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0004749; F:ribose phosphate diphosphokinase activity; IEA:EC.
									GO:0009116; P:nucleoside metabolic process; IEA:InterPro.::GO:0009156; P:ribonucleoside monophosphate biosynthetic process; IEA:InterPro.
31	Q8XHJ4	319	KPRS_CLOPE Ribose-phosphate pyrophosphokinase...	315	3e-89	276	48	64	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0016301; F:kinase activity; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0004749; F:ribose phosphate diphosphokinase activity; IEA:EC.
									GO:0009116; P:nucleoside metabolic process; IEA:InterPro.::GO:0009156; P:ribonucleoside monophosphate biosynthetic process; IEA:InterPro.

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