Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YER089C
Length:
464
Number of sequences:
5887
Description:
YER089C PTC2 SGDID:S000000891, Chr V from 337340-335946, Genome Release 64-1-1, reverse complement, Verified ORF, "Type 2C protein phosphatase (PP2C); dephosphorylates Hog1p to limit maximal osmostress induced kinase activity; dephosphorylates Ire1p to downregulate the unfolded protein response; dephosphorylates Cdc28p; inactivates the DNA damage checkpoint"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
1P39966    464   PP2C2_YEAST Protein phosphatase 2C homolog 2 ...4640     961     100     100GO:0005737; C:cytoplasm; IDA:SGD.::GO:0005634; C:nucleus; IDA:SGD.::GO:0008287; C:protein serine/threonine phosphatase complex; IEA:InterPro.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004722; F:protein serine/threonine phosphatase activity; IDA:SGD.
GO:0000077; P:DNA damage checkpoint; IGI:SGD.::GO:0030968; P:endoplasmic reticulum unfolded protein response; IMP:SGD.::GO:0000173; P:inactivation of MAPK activity involved in osmosensory signaling pathway; IMP:SGD.::GO:0006470; P:protein dephosphorylation; IDA:SGD.::GO:0000079; P:regulation of cyclin-dependent protein kinase activity; IMP:SGD.
2P34221    468   PP2C3_YEAST Protein phosphatase 2C homolog 3 ...4490     555     63     79GO:0005737; C:cytoplasm; IDA:SGD.::GO:0005634; C:nucleus; IDA:SGD.::GO:0008287; C:protein serine/threonine phosphatase complex; IEA:InterPro.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004722; F:protein serine/threonine phosphatase activity; IDA:SGD.
GO:0000173; P:inactivation of MAPK activity involved in osmosensory signaling pathway; IGI:SGD.::GO:0006470; P:protein dephosphorylation; IDA:SGD.::GO:0000079; P:regulation of cyclin-dependent protein kinase activity; IMP:SGD.
3Q09173    414   PP2C3_SCHPO Protein phosphatase 2C homolog 3 ...3097e-99     309     50     68GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.::GO:0008287; C:protein serine/threonine phosphatase complex; IEA:InterPro.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004722; F:protein serine/threonine phosphatase activity; IDA:PomBase.
GO:0000173; P:inactivation of MAPK activity involved in osmosensory signaling pathway; IMP:PomBase.::GO:0006470; P:protein dephosphorylation; IDA:PomBase.
4Q09172    370   PP2C2_SCHPO Protein phosphatase 2C homolog 2 ...3266e-98     305     49     65GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.::GO:0008287; C:protein serine/threonine phosphatase complex; IEA:InterPro.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004722; F:protein serine/threonine phosphatase activity; IDA:PomBase.
GO:0071470; P:cellular response to osmotic stress; IMP:PomBase.::GO:0030968; P:endoplasmic reticulum unfolded protein response; ISS:PomBase.::GO:0000173; P:inactivation of MAPK activity involved in osmosensory signaling pathway; IMP:PomBase.::GO:0006470; P:protein dephosphorylation; IDA:PomBase.
5P49596    356   PP2C2_CAEEL Probable protein phosphatase 2C T...3155e-80     258     44     61GO:0008287; C:protein serine/threonine phosphatase complex; IEA:InterPro.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004722; F:protein serine/threonine phosphatase activity; IEA:InterPro.
GO:0006470; P:protein dephosphorylation; IEA:InterPro.
6Q6ETK3    362   P2C11_ORYSJ Probable protein phosphatase 2C 1...3403e-65     220     39     54GO:0008287; C:protein serine/threonine phosphatase complex; IEA:InterPro.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004722; F:protein serine/threonine phosphatase activity; IEA:InterPro.
GO:0006470; P:protein dephosphorylation; IEA:InterPro.
7Q67UP9    368   P2C58_ORYSJ Probable protein phosphatase 2C 5...3401e-63     216     39     54GO:0008287; C:protein serine/threonine phosphatase complex; IEA:InterPro.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004722; F:protein serine/threonine phosphatase activity; IEA:InterPro.
GO:0006470; P:protein dephosphorylation; IEA:InterPro.
8O81716    355   P2C21_ARATH Probable protein phosphatase 2C 2...3411e-61     210     38     54GO:0005886; C:plasma membrane; IDA:TAIR.::GO:0008287; C:protein serine/threonine phosphatase complex; IEA:InterPro.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004722; F:protein serine/threonine phosphatase activity; IEA:InterPro.
GO:0006470; P:protein dephosphorylation; IEA:InterPro.::GO:0009737; P:response to abscisic acid stimulus; IDA:TAIR.
9Q9SZ53    357   P2C60_ARATH Probable protein phosphatase 2C 6...3404e-60     206     37     52GO:0005886; C:plasma membrane; IDA:TAIR.::GO:0008287; C:protein serine/threonine phosphatase complex; IEA:InterPro.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004722; F:protein serine/threonine phosphatase activity; IEA:InterPro.
GO:0006470; P:protein dephosphorylation; IEA:InterPro.
10P49444    300   PP2C1_PARTE Protein phosphatase 2C 1 OS=Param...3097e-60     204     37     55GO:0016020; C:membrane; IEA:UniProtKB-SubCell.::GO:0008287; C:protein serine/threonine phosphatase complex; IEA:InterPro.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004722; F:protein serine/threonine phosphatase activity; IEA:InterPro.
GO:0006470; P:protein dephosphorylation; IEA:InterPro.
11A0BLX0    300   PP2C2_PARTE Probable protein phosphatase 2C 2...3098e-60     204     38     55GO:0016020; C:membrane; IEA:UniProtKB-SubCell.::GO:0008287; C:protein serine/threonine phosphatase complex; IEA:InterPro.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004722; F:protein serine/threonine phosphatase activity; IEA:InterPro.
GO:0006470; P:protein dephosphorylation; IEA:InterPro.
12Q653S3    362   P2C70_ORYSJ Probable protein phosphatase 2C 7...3452e-59     205     35     52GO:0008287; C:protein serine/threonine phosphatase complex; IEA:InterPro.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004722; F:protein serine/threonine phosphatase activity; IEA:InterPro.
GO:0006470; P:protein dephosphorylation; IEA:InterPro.
13A0BQL0    300   PP2C3_PARTE Probable protein phosphatase 2C 3...3093e-59     202     38     55GO:0016020; C:membrane; IEA:UniProtKB-SubCell.::GO:0008287; C:protein serine/threonine phosphatase complex; IEA:InterPro.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004722; F:protein serine/threonine phosphatase activity; IEA:InterPro.
GO:0006470; P:protein dephosphorylation; IEA:InterPro.
14A0DSB3    295   PP2C6_PARTE Probable protein phosphatase 2C 6...3051e-57     198     36     56GO:0016020; C:membrane; IEA:UniProtKB-SubCell.::GO:0008287; C:protein serine/threonine phosphatase complex; IEA:InterPro.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004722; F:protein serine/threonine phosphatase activity; IEA:InterPro.
GO:0006470; P:protein dephosphorylation; IEA:InterPro.
15A0CUB5    295   PP2C5_PARTE Probable protein phosphatase 2C 5...3052e-57     197     35     56GO:0016020; C:membrane; IEA:UniProtKB-SubCell.::GO:0008287; C:protein serine/threonine phosphatase complex; IEA:InterPro.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004722; F:protein serine/threonine phosphatase activity; IEA:InterPro.
GO:0006470; P:protein dephosphorylation; IEA:InterPro.
16Q7XU84    352   P2C42_ORYSJ Probable protein phosphatase 2C 4...3286e-57     198     38     52GO:0008287; C:protein serine/threonine phosphatase complex; IEA:InterPro.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004722; F:protein serine/threonine phosphatase activity; IEA:InterPro.
GO:0006470; P:protein dephosphorylation; IEA:InterPro.
17A0DTY1    301   PP2C4_PARTE Probable protein phosphatase 2C 4...3078e-57     196     38     56GO:0016020; C:membrane; IEA:UniProtKB-SubCell.::GO:0008287; C:protein serine/threonine phosphatase complex; IEA:InterPro.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004722; F:protein serine/threonine phosphatase activity; IEA:InterPro.
GO:0006470; P:protein dephosphorylation; IEA:InterPro.
18P35815    390   PPM1B_RAT Protein phosphatase 1B OS=Rattus no...3062e-47     173     34     52GO:0008287; C:protein serine/threonine phosphatase complex; IEA:InterPro.
GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0030145; F:manganese ion binding; IEA:InterPro.::GO:0004722; F:protein serine/threonine phosphatase activity; IEA:InterPro.
GO:0006470; P:protein dephosphorylation; IEA:InterPro.
19P49443    382   PPM1A_MOUSE Protein phosphatase 1A OS=Mus mus...3013e-47     172     32     53GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0008287; C:protein serine/threonine phosphatase complex; IEA:InterPro.
GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0030145; F:manganese ion binding; IEA:InterPro.::GO:0070412; F:R-SMAD binding; ISS:UniProtKB.
GO:0006470; P:protein dephosphorylation; IDA:MGI.
20P36993    390   PPM1B_MOUSE Protein phosphatase 1B OS=Mus mus...3063e-47     173     34     53GO:0008287; C:protein serine/threonine phosphatase complex; IEA:InterPro.
GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0030145; F:manganese ion binding; IEA:InterPro.::GO:0004722; F:protein serine/threonine phosphatase activity; IEA:InterPro.
GO:0006470; P:protein dephosphorylation; IEA:InterPro.
21P20650    382   PPM1A_RAT Protein phosphatase 1A OS=Rattus no...3013e-47     172     32     53GO:0005624; C:membrane fraction; IDA:UniProtKB.::GO:0043005; C:neuron projection; IDA:UniProtKB.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0008287; C:protein serine/threonine phosphatase complex; IEA:InterPro.
GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0030145; F:manganese ion binding; IEA:InterPro.::GO:0008022; F:protein C-terminus binding; IPI:UniProtKB.::GO:0070412; F:R-SMAD binding; ISS:UniProtKB.
22P35813    382   PPM1A_HUMAN Protein phosphatase 1A OS=Homo sa...3014e-47     172     32     53GO:0005829; C:cytosol; TAS:Reactome.::GO:0005634; C:nucleus; IDA:UniProtKB.::GO:0008287; C:protein serine/threonine phosphatase complex; IEA:InterPro.
GO:0033192; F:calmodulin-dependent protein phosphatase activity; IDA:UniProtKB.::GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0030145; F:manganese ion binding; IEA:InterPro.::GO:0070412; F:R-SMAD binding; IPI:UniProtKB.::GO:0004871; F:signal transducer activity; IMP:UniProtKB.
GO:0007050; P:cell cycle arrest; TAS:Reactome.::GO:0008286; P:insulin receptor signaling pathway; TAS:Reactome.::GO:0010991; P:negative regulation of SMAD protein complex assembly; IDA:UniProtKB.::GO:0030512; P:negative regulation of transforming growth factor beta receptor signaling pathway; IDA:UniProtKB.::GO:0035970; P:peptidyl-threonine dephosphorylation; IDA:UniProtKB.::GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB cascade; IMP:UniProtKB.::GO:0045893; P:positive regulation of transcription, DNA-dependent; IDA:BHF-UCL.::GO:0030177; P:positive regulation of Wnt receptor signaling pathway; IDA:BHF-UCL.::GO:0016055; P:Wnt receptor signaling pathway; IDA:BHF-UCL.
23P35814    382   PPM1A_RABIT Protein phosphatase 1A OS=Oryctol...3014e-47     172     32     53GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0008287; C:protein serine/threonine phosphatase complex; IEA:InterPro.
GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0030145; F:manganese ion binding; IEA:InterPro.::GO:0070412; F:R-SMAD binding; ISS:UniProtKB.::GO:0004871; F:signal transducer activity; ISS:AgBase.
GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB cascade; ISS:AgBase.::GO:0006470; P:protein dephosphorylation; ISS:AgBase.
24O62829    382   PPM1A_BOVIN Protein phosphatase 1A OS=Bos tau...3014e-47     172     32     53GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0008287; C:protein serine/threonine phosphatase complex; IEA:InterPro.
GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0030145; F:manganese ion binding; IEA:InterPro.::GO:0004722; F:protein serine/threonine phosphatase activity; IEA:InterPro.::GO:0070412; F:R-SMAD binding; ISS:UniProtKB.::GO:0004871; F:signal transducer activity; ISS:AgBase.
GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB cascade; ISS:AgBase.::GO:0006470; P:protein dephosphorylation; ISS:AgBase.
25O75688    479   PPM1B_HUMAN Protein phosphatase 1B OS=Homo sa...3066e-47     174     34     51GO:0005829; C:cytosol; TAS:Reactome.::GO:0008287; C:protein serine/threonine phosphatase complex; IEA:InterPro.
GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0030145; F:manganese ion binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004722; F:protein serine/threonine phosphatase activity; IDA:UniProtKB.
GO:0019221; P:cytokine-mediated signaling pathway; TAS:Reactome.::GO:0035970; P:peptidyl-threonine dephosphorylation; IDA:UniProtKB.::GO:0006470; P:protein dephosphorylation; IEA:InterPro.
26O62830    484   PPM1B_BOVIN Protein phosphatase 1B OS=Bos tau...3068e-47     174     34     51GO:0008287; C:protein serine/threonine phosphatase complex; IEA:InterPro.
GO:0000287; F:magnesium ion binding; IEA:InterPro.::GO:0030145; F:manganese ion binding; IEA:InterPro.::GO:0004722; F:protein serine/threonine phosphatase activity; IEA:InterPro.
GO:0006470; P:protein dephosphorylation; IEA:InterPro.
27P38089    393   PP2C4_YEAST Protein phosphatase 2C homolog 4 ...3915e-43     161     29     47GO:0005737; C:cytoplasm; IDA:SGD.::GO:0008287; C:protein serine/threonine phosphatase complex; IEA:InterPro.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004722; F:protein serine/threonine phosphatase activity; IDA:SGD.
GO:0006470; P:protein dephosphorylation; IDA:SGD.
28A3A8W2    340   P2C21_ORYSJ Probable protein phosphatase 2C 2...3084e-42     157     33     49GO:0008287; C:protein serine/threonine phosphatase complex; IEA:InterPro.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004722; F:protein serine/threonine phosphatase activity; IEA:InterPro.
GO:0006470; P:protein dephosphorylation; IEA:InterPro.
29Q7K4Q5    662   Y0417_DROME Probable protein phosphatase CG10...1113e-16     85.1     40     59GO:0008287; C:protein serine/threonine phosphatase complex; IEA:InterPro.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004722; F:protein serine/threonine phosphatase activity; NAS:FlyBase.
GO:0006470; P:protein dephosphorylation; NAS:FlyBase.
30P49595    491   PP2C1_CAEEL Probable protein phosphatase 2C F...1150.000000000008     70.9     31     56GO:0008287; C:protein serine/threonine phosphatase complex; IEA:InterPro.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004722; F:protein serine/threonine phosphatase activity; IEA:InterPro.
GO:0006470; P:protein dephosphorylation; IEA:InterPro.
31Q4R4V2    547   PPM1G_MACFA Protein phosphatase 1G OS=Macaca ...1182e-18     91.3     40     60GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0008287; C:protein serine/threonine phosphatase complex; IEA:InterPro.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004722; F:protein serine/threonine phosphatase activity; IEA:InterPro.
GO:0006470; P:protein dephosphorylation; IEA:InterPro.
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