Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YER089C
Length:
464
Number of sequences:
5887
Description:
YER089C PTC2 SGDID:S000000891, Chr V from 337340-335946, Genome Release 64-1-1, reverse complement, Verified ORF, "Type 2C protein phosphatase (PP2C); dephosphorylates Hog1p to limit maximal osmostress induced kinase activity; dephosphorylates Ire1p to downregulate the unfolded protein response; dephosphorylates Cdc28p; inactivates the DNA damage checkpoint"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
181Q10S32    399   P2C28_ORYSJ Probable protein phosphatase 2C 2...2670.000000003     62.4     25     41GO:0008287; C:protein serine/threonine phosphatase complex; IEA:InterPro.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004722; F:protein serine/threonine phosphatase activity; IEA:InterPro.
GO:0006470; P:protein dephosphorylation; IEA:InterPro.
182Q6K6N7    518   P2C14_ORYSJ Probable protein phosphatase 2C 1...2810.000000003     62.8     27     44
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004721; F:phosphoprotein phosphatase activity; IEA:UniProtKB-KW.
183Q8H063    392   P2C29_ORYSJ Probable protein phosphatase 2C 2...2510.000000003     62.4     25     39GO:0008287; C:protein serine/threonine phosphatase complex; IEA:InterPro.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004722; F:protein serine/threonine phosphatase activity; IEA:InterPro.
GO:0006470; P:protein dephosphorylation; IEA:InterPro.
184Q9SL76    1094   P2C19_ARATH Protein phosphatase 2C and cyclic...2560.000000003     63.2     26     45GO:0005952; C:cAMP-dependent protein kinase complex; IEA:InterPro.::GO:0005886; C:plasma membrane; IDA:TAIR.::GO:0008287; C:protein serine/threonine phosphatase complex; IEA:InterPro.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008603; F:cAMP-dependent protein kinase regulator activity; IEA:InterPro.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.::GO:0004722; F:protein serine/threonine phosphatase activity; IEA:InterPro.
GO:0006470; P:protein dephosphorylation; IEA:InterPro.::GO:0001932; P:regulation of protein phosphorylation; IEA:InterPro.
185Q9SUF4    212   P2C53_ARATH Putative protein phosphatase 2C 5...1970.000000004     60.1     28     44
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004721; F:phosphoprotein phosphatase activity; IEA:UniProtKB-KW.
186Q84JD5    393   P2C68_ARATH Probable protein phosphatase 2C 6...2400.000000007     61.2     26     40GO:0008287; C:protein serine/threonine phosphatase complex; IEA:InterPro.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004722; F:protein serine/threonine phosphatase activity; IEA:InterPro.
GO:0006470; P:protein dephosphorylation; IEA:InterPro.
187Q7XTC7    461   P2C40_ORYSJ Probable protein phosphatase 2C 4...2050.00000001     60.5     28     44
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004721; F:phosphoprotein phosphatase activity; IEA:UniProtKB-KW.
188Q6Z8B9    389   P2C12_ORYSJ Probable protein phosphatase 2C 1...1740.00000001     60.1     30     47
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004721; F:phosphoprotein phosphatase activity; IEA:UniProtKB-KW.
189Q0JMD4    485   P2C03_ORYSJ Probable protein phosphatase 2C 3...2120.00000004     58.9     28     43
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004721; F:phosphoprotein phosphatase activity; IEA:UniProtKB-KW.
190P23466    1839   CYAA_LACKL Adenylate cyclase OS=Lachancea klu...2530.00000004     59.7     26     44
GO:0004016; F:adenylate cyclase activity; IEA:EC.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0035556; P:intracellular signal transduction; IEA:InterPro.
191Q01513    2145   CYAA_PODAS Adenylate cyclase OS=Podospora ans...2640.00000005     59.3     24     42
GO:0004016; F:adenylate cyclase activity; IEA:EC.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.
GO:0035556; P:intracellular signal transduction; IEA:InterPro.
192O81760    380   P2C63_ARATH Probable protein phosphatase 2C 6...2310.00000007     58.2     26     42GO:0008287; C:protein serine/threonine phosphatase complex; IEA:InterPro.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004722; F:protein serine/threonine phosphatase activity; IEA:InterPro.
GO:0006470; P:protein dephosphorylation; IEA:InterPro.
193Q12511    572   PP2C5_YEAST Protein phosphatase 2C homolog 5 ...2590.00000007     58.5     26     40GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0031966; C:mitochondrial membrane; IEA:UniProtKB-SubCell.::GO:0008287; C:protein serine/threonine phosphatase complex; IEA:InterPro.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004722; F:protein serine/threonine phosphatase activity; IDA:SGD.
GO:0043085; P:positive regulation of catalytic activity; IMP:SGD.::GO:0006470; P:protein dephosphorylation; IDA:SGD.
194Q67J17    422   P2C69_ORYSJ Probable protein phosphatase 2C 6...2080.0000001     57.4     27     46
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004721; F:phosphoprotein phosphatase activity; IEA:UniProtKB-KW.
195P49606    2493   CYAA_USTMA Adenylate cyclase OS=Ustilago mayd...2350.0000001     58.2     28     43
GO:0004016; F:adenylate cyclase activity; IEA:EC.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0035556; P:intracellular signal transduction; IEA:InterPro.
196Q94H98    380   P2C34_ORYSJ Probable protein phosphatase 2C 3...3300.0000002     56.6     24     39GO:0008287; C:protein serine/threonine phosphatase complex; IEA:InterPro.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004722; F:protein serine/threonine phosphatase activity; IEA:InterPro.
GO:0006470; P:protein dephosphorylation; IEA:InterPro.
197Q5MFV5    380   P2C34_ORYSI Probable protein phosphatase 2C 3...3300.0000002     56.6     24     39GO:0008287; C:protein serine/threonine phosphatase complex; IEA:InterPro.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004722; F:protein serine/threonine phosphatase activity; IEA:InterPro.
GO:0006470; P:protein dephosphorylation; IEA:InterPro.
198Q3EAZ3    245   P2C45_ARATH Putative protein phosphatase 2C-l...1930.0000004     54.7     26     40
GO:0003824; F:catalytic activity; IEA:InterPro.
199P35816    538   PDP1_BOVIN [Pyruvate dehydrogenase [acetyl-tr...2020.000002     53.5     30     43GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell.::GO:0008287; C:protein serine/threonine phosphatase complex; IEA:InterPro.
GO:0004741; F:[pyruvate dehydrogenase (lipoamide) phosphatase activity; IEA:EC.::GO:0005509; F:calcium ion binding; IDA:UniProtKB.::GO:0000287; F:magnesium ion binding; NAS:UniProtKB.::GO:0004722; F:protein serine/threonine phosphatase activity; IEA:InterPro.
GO:0006470; P:protein dephosphorylation; IEA:InterPro.]
200O88483    538   PDP1_RAT [Pyruvate dehydrogenase [acetyl-tran...2020.000002     53.5     30     43GO:0005759; C:mitochondrial matrix; TAS:RGD.::GO:0008287; C:protein serine/threonine phosphatase complex; IEA:InterPro.
GO:0004741; F:[pyruvate dehydrogenase (lipoamide) phosphatase activity; IDA:RGD.::GO:0005509; F:calcium ion binding; ISS:UniProtKB.::GO:0000287; F:magnesium ion binding; IDA:RGD.::GO:0004724; F:magnesium-dependent protein serine/threonine phosphatase activity; IDA:RGD.::GO:0032403; F:protein complex binding; IMP:RGD.
GO:0043085; P:positive regulation of catalytic activity; IC:RGD.::GO:0006470; P:protein dephosphorylation; IDA:RGD.]
201Q5RA52    537   PDP1_PONAB [Pyruvate dehydrogenase [acetyl-tr...2020.000003     53.5     30     43GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell.::GO:0008287; C:protein serine/threonine phosphatase complex; IEA:InterPro.
GO:0004741; F:[pyruvate dehydrogenase (lipoamide) phosphatase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004722; F:protein serine/threonine phosphatase activity; IEA:InterPro.
GO:0006470; P:protein dephosphorylation; IEA:InterPro.]
202Q9P0J1    537   PDP1_HUMAN [Pyruvate dehydrogenase [acetyl-tr...2020.000003     53.5     30     43GO:0005759; C:mitochondrial matrix; TAS:Reactome.::GO:0008287; C:protein serine/threonine phosphatase complex; IEA:InterPro.
GO:0004741; F:[pyruvate dehydrogenase (lipoamide) phosphatase activity; IEA:EC.
GO:0035970; P:peptidyl-threonine dephosphorylation; IDA:UniProtKB.::GO:0006090; P:pyruvate metabolic process; TAS:Reactome.::GO:0010510; P:regulation of acetyl-CoA biosynthetic process from pyruvate; TAS:Reactome.]
203Q3UV70    538   PDP1_MOUSE [Pyruvate dehydrogenase [acetyl-tr...2020.000003     53.5     30     43GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell.::GO:0008287; C:protein serine/threonine phosphatase complex; IEA:InterPro.
GO:0004741; F:[pyruvate dehydrogenase (lipoamide) phosphatase activity; IEA:EC.::GO:0005509; F:calcium ion binding; ISS:UniProtKB.::GO:0004722; F:protein serine/threonine phosphatase activity; IEA:InterPro.
GO:0006470; P:protein dephosphorylation; IEA:InterPro.]
204Q9WTR8    1696   PHLP1_RAT PH domain leucine-rich repeat prote...2030.000008     52.4     26     42GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.::GO:0005624; C:membrane fraction; IDA:RGD.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0004722; F:protein serine/threonine phosphatase activity; IDA:RGD.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0007623; P:circadian rhythm; IEP:RGD.::GO:0006470; P:protein dephosphorylation; IDA:RGD.
205P08678    2026   CYAA_YEAST Adenylate cyclase OS=Saccharomyces...1860.00003     50.8     24     43GO:0005739; C:mitochondrion; IDA:SGD.::GO:0005886; C:plasma membrane; IDA:SGD.
GO:0004016; F:adenylate cyclase activity; IDA:SGD.::GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0000287; F:magnesium ion binding; IEA:InterPro.
GO:0035556; P:intracellular signal transduction; IEA:InterPro.
206Q8CHE4    1687   PHLP1_MOUSE PH domain leucine-rich repeat-con...2460.00003     50.4     26     41GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0004721; F:phosphoprotein phosphatase activity; IEA:UniProtKB-KW.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
207Q9LUS8    493   P2C40_ARATH Probable protein phosphatase 2C 4...1530.00005     49.3     29     47
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0004721; F:phosphoprotein phosphatase activity; IEA:UniProtKB-KW.
208O60346    1717   PHLP1_HUMAN PH domain leucine-rich repeat-con...2570.00009     48.9     26     39GO:0005829; C:cytosol; TAS:Reactome.::GO:0016020; C:membrane; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0005543; F:phospholipid binding; IEA:InterPro.::GO:0004722; F:protein serine/threonine phosphatase activity; TAS:Reactome.
GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.::GO:0007173; P:epidermal growth factor receptor signaling pathway; TAS:Reactome.::GO:0008543; P:fibroblast growth factor receptor signaling pathway; TAS:Reactome.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0048015; P:phosphatidylinositol-mediated signaling; TAS:Reactome.
209O88484    530   PDP2_RAT [Pyruvate dehydrogenase [acetyl-tran...2010.0002     47.8     28     42GO:0019910; C:mitochondrial pyruvate dehydrogenase (lipoamide) phosphatase complex; TAS:RGD.::GO:0008287; C:protein serine/threonine phosphatase complex; IEA:InterPro.
GO:0004741; F:[pyruvate dehydrogenase (lipoamide) phosphatase activity; IDA:RGD.::GO:0000287; F:magnesium ion binding; IC:RGD.::GO:0004724; F:magnesium-dependent protein serine/threonine phosphatase activity; IDA:RGD.
GO:0009758; P:carbohydrate utilization; TAS:RGD.::GO:0035970; P:peptidyl-threonine dephosphorylation; IDA:UniProtKB.]
210Q0D629    223   P2C63_ORYSJ Putative protein phosphatase 2C 6...1190.0002     46.2     32     44
GO:0004721; F:phosphoprotein phosphatase activity; IEA:UniProtKB-KW.
211Q9P2J9    529   PDP2_HUMAN [Pyruvate dehydrogenase [acetyl-tr...1500.0004     46.6     29     43GO:0005759; C:mitochondrial matrix; TAS:Reactome.::GO:0008287; C:protein serine/threonine phosphatase complex; IEA:InterPro.
GO:0004741; F:[pyruvate dehydrogenase (lipoamide) phosphatase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0006090; P:pyruvate metabolic process; TAS:Reactome.::GO:0010510; P:regulation of acetyl-CoA biosynthetic process from pyruvate; TAS:Reactome.]
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