rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
61 | Q0VCQ1 | 445 | CTBP2_BOVIN C-terminal-binding protein 2 OS=B... | 344 | 4e-31 | 127 | 31 | 46 | GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0045202; C:synapse; IEA:UniProtKB-SubCell.::GO:0017053; C:transcriptional repressor complex; ISS:UniProtKB. | | | | | | | | | | GO:0051287; F:NAD binding; IEA:InterPro.::GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro. | | | | | | | | | | GO:0045892; P:negative regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0050872; P:white fat cell differentiation; ISS:UniProtKB. | 62 | A6TFG7 | 323 | GHRB_KLEP7 Glyoxylate/hydroxypyruvate reducta... | 261 | 7e-31 | 125 | 32 | 51 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0030267; F:glyoxylate reductase (NADP) activity; IEA:EC.::GO:0016618; F:hydroxypyruvate reductase activity; IEA:EC.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | | 63 | Q59642 | 331 | LDHD_PEDAC D-lactate dehydrogenase OS=Pedioco... | 289 | 8e-31 | 125 | 28 | 52 | | | | | | | | | | | GO:0008720; F:D-lactate dehydrogenase activity; IEA:EC.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | | 64 | P44501 | 331 | DDH_HAEIN 2-hydroxyacid dehydrogenase homolog... | 235 | 8e-31 | 125 | 34 | 51 | | | | | | | | | | | GO:0051287; F:NAD binding; IEA:InterPro.::GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro. | | | | | | | | | | | 65 | Q9Z2F5 | 430 | CTBP1_RAT C-terminal-binding protein 1 OS=Rat... | 271 | 1e-30 | 126 | 34 | 49 | GO:0005829; C:cytosol; IDA:RGD.::GO:0017053; C:transcriptional repressor complex; ISS:UniProtKB. | | | | | | | | | | GO:0051287; F:NAD binding; IDA:UniProtKB.::GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro.::GO:0042803; F:protein homodimerization activity; IPI:UniProtKB.::GO:0003714; F:transcription corepressor activity; TAS:RGD.::GO:0016746; F:transferase activity, transferring acyl groups; TAS:RGD. | | | | | | | | | | GO:0006944; P:cellular membrane fusion; TAS:RGD.::GO:0007030; P:Golgi organization; IMP:RGD.::GO:0045892; P:negative regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0050872; P:white fat cell differentiation; ISS:UniProtKB. | 66 | Q13363 | 440 | CTBP1_HUMAN C-terminal-binding protein 1 OS=H... | 271 | 1e-30 | 126 | 34 | 49 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IDA:HPA.::GO:0017053; C:transcriptional repressor complex; ISS:UniProtKB. | | | | | | | | | | GO:0051287; F:NAD binding; ISS:UniProtKB.::GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro.::GO:0008022; F:protein C-terminus binding; TAS:ProtInc.::GO:0019904; F:protein domain specific binding; IPI:UniProtKB.::GO:0001106; F:RNA polymerase II transcription corepressor activity; IDA:BHF-UCL.::GO:0008134; F:transcription factor binding; IPI:UniProtKB. | | | | | | | | | | GO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW.::GO:0008285; P:negative regulation of cell proliferation; TAS:ProtInc.::GO:0090241; P:negative regulation of histone H4 acetylation; IMP:BHF-UCL.::GO:0031065; P:positive regulation of histone deacetylation; IMP:BHF-UCL.::GO:0006468; P:protein phosphorylation; TAS:ProtInc.::GO:0051726; P:regulation of cell cycle; IMP:BHF-UCL.::GO:0034401; P:regulation of transcription by chromatin organization; IMP:BHF-UCL.::GO:0019079; P:viral genome replication; TAS:ProtInc.::GO:0050872; P:white fat cell differentiation; ISS:UniProtKB. | 67 | O88712 | 441 | CTBP1_MOUSE C-terminal-binding protein 1 OS=M... | 271 | 1e-30 | 126 | 34 | 49 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005667; C:transcription factor complex; IDA:MGI.::GO:0017053; C:transcriptional repressor complex; IDA:UniProtKB. | | | | | | | | | | GO:0051287; F:NAD binding; ISS:UniProtKB.::GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:MGI.::GO:0008134; F:transcription factor binding; IPI:UniProtKB. | | | | | | | | | | GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IMP:MGI.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0050872; P:white fat cell differentiation; IDA:UniProtKB. | 68 | Q9UYR1 | 335 | GYAR_PYRAB Glyoxylate reductase OS=Pyrococcus... | 322 | 2e-30 | 124 | 34 | 52 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0047964; F:glyoxylate reductase activity; IEA:HAMAP.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | | 69 | A1JT62 | 326 | GHRB_YERE8 Glyoxylate/hydroxypyruvate reducta... | 290 | 3e-30 | 123 | 31 | 49 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0030267; F:glyoxylate reductase (NADP) activity; IEA:EC.::GO:0016618; F:hydroxypyruvate reductase activity; IEA:EC.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | | 70 | Q9P7Q1 | 332 | DDH2_SCHPO 2-hydroxyacid dehydrogenase homolo... | 233 | 5e-30 | 123 | 32 | 52 | GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase. | | | | | | | | | | GO:0051287; F:NAD binding; IEA:InterPro.::GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro. | | | | | | | | | | | 71 | P56545 | 445 | CTBP2_HUMAN C-terminal-binding protein 2 OS=H... | 344 | 5e-30 | 124 | 31 | 46 | GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0045202; C:synapse; IEA:UniProtKB-SubCell.::GO:0017053; C:transcriptional repressor complex; ISS:UniProtKB. | | | | | | | | | | GO:0051287; F:NAD binding; IEA:InterPro.::GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct. | | | | | | | | | | GO:0008285; P:negative regulation of cell proliferation; TAS:ProtInc.::GO:0045892; P:negative regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0019079; P:viral genome replication; TAS:ProtInc.::GO:0050872; P:white fat cell differentiation; ISS:UniProtKB. | 72 | Q1CD80 | 326 | GHRB_YERPN Glyoxylate/hydroxypyruvate reducta... | 304 | 6e-30 | 122 | 31 | 49 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0030267; F:glyoxylate reductase (NADP) activity; IEA:EC.::GO:0016618; F:hydroxypyruvate reductase activity; IEA:EC.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | | 73 | A4W577 | 324 | GHRB_ENT38 Glyoxylate/hydroxypyruvate reducta... | 275 | 7e-30 | 122 | 30 | 51 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0030267; F:glyoxylate reductase (NADP) activity; IEA:EC.::GO:0016618; F:hydroxypyruvate reductase activity; IEA:EC.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | | 74 | Q663W4 | 326 | GHRB_YERPS Glyoxylate/hydroxypyruvate reducta... | 304 | 7e-30 | 122 | 31 | 49 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0030267; F:glyoxylate reductase (NADP) activity; IEA:EC.::GO:0016618; F:hydroxypyruvate reductase activity; IEA:EC.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | | 75 | A4TGN1 | 326 | GHRB_YERPP Glyoxylate/hydroxypyruvate reducta... | 304 | 7e-30 | 122 | 31 | 49 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0030267; F:glyoxylate reductase (NADP) activity; IEA:EC.::GO:0016618; F:hydroxypyruvate reductase activity; IEA:EC.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | | 76 | A9R4G6 | 326 | GHRB_YERPG Glyoxylate/hydroxypyruvate reducta... | 304 | 7e-30 | 122 | 31 | 49 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0030267; F:glyoxylate reductase (NADP) activity; IEA:EC.::GO:0016618; F:hydroxypyruvate reductase activity; IEA:EC.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | | 77 | Q0W9V5 | 326 | GHRB_YERPE Glyoxylate/hydroxypyruvate reducta... | 304 | 7e-30 | 122 | 31 | 49 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0030267; F:glyoxylate reductase (NADP) activity; IEA:EC.::GO:0016618; F:hydroxypyruvate reductase activity; IEA:EC.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | | 78 | B2K7F1 | 326 | GHRB_YERPB Glyoxylate/hydroxypyruvate reducta... | 304 | 7e-30 | 122 | 31 | 49 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0030267; F:glyoxylate reductase (NADP) activity; IEA:EC.::GO:0016618; F:hydroxypyruvate reductase activity; IEA:EC.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | | 79 | Q1C3K4 | 326 | GHRB_YERPA Glyoxylate/hydroxypyruvate reducta... | 304 | 7e-30 | 122 | 31 | 49 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0030267; F:glyoxylate reductase (NADP) activity; IEA:EC.::GO:0016618; F:hydroxypyruvate reductase activity; IEA:EC.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | | 80 | A7FPA2 | 326 | GHRB_YERP3 Glyoxylate/hydroxypyruvate reducta... | 304 | 7e-30 | 122 | 31 | 49 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0030267; F:glyoxylate reductase (NADP) activity; IEA:EC.::GO:0016618; F:hydroxypyruvate reductase activity; IEA:EC.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | | 81 | Q9EQH5 | 445 | CTBP2_RAT C-terminal-binding protein 2 OS=Rat... | 344 | 9e-30 | 124 | 30 | 46 | GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0045202; C:synapse; IEA:UniProtKB-SubCell.::GO:0017053; C:transcriptional repressor complex; ISS:UniProtKB. | | | | | | | | | | GO:0051287; F:NAD binding; IEA:InterPro.::GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro. | | | | | | | | | | GO:0045892; P:negative regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0050872; P:white fat cell differentiation; ISS:UniProtKB. | 82 | P56546 | 445 | CTBP2_MOUSE C-terminal-binding protein 2 OS=M... | 344 | 1e-29 | 124 | 30 | 46 | GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0045202; C:synapse; IEA:UniProtKB-SubCell.::GO:0017053; C:transcriptional repressor complex; IDA:UniProtKB. | | | | | | | | | | GO:0051287; F:NAD binding; IEA:InterPro.::GO:0016616; F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor; IEA:InterPro.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0003714; F:transcription corepressor activity; IDA:MGI. | | | | | | | | | | GO:0045892; P:negative regulation of transcription, DNA-dependent; IDA:UniProtKB.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0050872; P:white fat cell differentiation; IDA:UniProtKB. | 83 | B1LJB3 | 324 | GHRB_ECOSM Glyoxylate/hydroxypyruvate reducta... | 256 | 1e-29 | 122 | 32 | 50 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0030267; F:glyoxylate reductase (NADP) activity; IEA:EC.::GO:0016618; F:hydroxypyruvate reductase activity; IEA:EC.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | | 84 | Q54UF7 | 340 | LDHD_DICDI Putative D-lactate dehydrogenase O... | 323 | 1e-29 | 122 | 29 | 47 | GO:0045335; C:phagocytic vesicle; IDA:dictyBase. | | | | | | | | | | GO:0008720; F:D-lactate dehydrogenase activity; ISS:dictyBase.::GO:0051287; F:NAD binding; ISS:dictyBase. | | | | | | | | | | GO:0019652; P:lactate fermentation to propionate and acetate; ISS:dictyBase. | 85 | P37666 | 324 | GHRB_ECOLI Glyoxylate/hydroxypyruvate reducta... | 256 | 1e-29 | 121 | 32 | 50 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0008873; F:gluconate 2-dehydrogenase activity; IEA:EC.::GO:0030267; F:glyoxylate reductase (NADP) activity; IEA:EC.::GO:0016618; F:hydroxypyruvate reductase activity; IEA:EC.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | GO:0019521; P:D-gluconate metabolic process; IEA:UniProtKB-KW. | 86 | Q8FCF1 | 324 | GHRB_ECOL6 Glyoxylate/hydroxypyruvate reducta... | 256 | 1e-29 | 121 | 32 | 50 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0030267; F:glyoxylate reductase (NADP) activity; IEA:EC.::GO:0016618; F:hydroxypyruvate reductase activity; IEA:EC.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | | 87 | B1X8G8 | 324 | GHRB_ECODH Glyoxylate/hydroxypyruvate reducta... | 256 | 1e-29 | 121 | 32 | 50 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0030267; F:glyoxylate reductase (NADP) activity; IEA:EC.::GO:0016618; F:hydroxypyruvate reductase activity; IEA:EC.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | | 88 | C4ZXE2 | 324 | GHRB_ECOBW Glyoxylate/hydroxypyruvate reducta... | 256 | 1e-29 | 121 | 32 | 50 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0030267; F:glyoxylate reductase (NADP) activity; IEA:EC.::GO:0016618; F:hydroxypyruvate reductase activity; IEA:EC.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | | 89 | B2U573 | 324 | GHRB_SHIB3 Glyoxylate/hydroxypyruvate reducta... | 256 | 2e-29 | 121 | 32 | 50 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0030267; F:glyoxylate reductase (NADP) activity; IEA:EC.::GO:0016618; F:hydroxypyruvate reductase activity; IEA:EC.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | | 90 | Q1R543 | 324 | GHRB_ECOUT Glyoxylate/hydroxypyruvate reducta... | 256 | 2e-29 | 121 | 32 | 50 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0030267; F:glyoxylate reductase (NADP) activity; IEA:EC.::GO:0016618; F:hydroxypyruvate reductase activity; IEA:EC.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | | 91 | B6I3C3 | 324 | GHRB_ECOSE Glyoxylate/hydroxypyruvate reducta... | 256 | 2e-29 | 121 | 32 | 50 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0030267; F:glyoxylate reductase (NADP) activity; IEA:EC.::GO:0016618; F:hydroxypyruvate reductase activity; IEA:EC.::GO:0051287; F:NAD binding; IEA:InterPro. | | | | | | | | | | |