Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YER075C
Length:
928
Number of sequences:
5887
Description:
YER075C PTP3 SGDID:S000000877, Chr V from 311199-308413, Genome Release 64-1-1, reverse complement, Verified ORF, "Phosphotyrosine-specific protein phosphatase involved in the inactivation of mitogen-activated protein kinase (MAPK) during osmolarity sensing; dephosporylates Hog1p MAPK and regulates its localization; localized to the cytoplasm"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
1P40048    928   PTP3_YEAST Tyrosine-protein phosphatase 3 OS=...9280     1908     100     100GO:0005737; C:cytoplasm; IDA:SGD.::GO:0005634; C:nucleus; IDA:SGD.
GO:0004725; F:protein tyrosine phosphatase activity; IDA:SGD.
GO:0071511; P:inactivation of MAPK activity involved in conjugation with cellular fusion; IMP:SGD.::GO:0000173; P:inactivation of MAPK activity involved in osmosensory signaling pathway; IMP:SGD.::GO:0032880; P:regulation of protein localization; IMP:SGD.::GO:0043937; P:regulation of sporulation; IGI:SGD.
2P29461    750   PTP2_YEAST Tyrosine-protein phosphatase 2 OS=...5345e-27     121     27     41GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IDA:SGD.
GO:0004725; F:protein tyrosine phosphatase activity; IDA:SGD.
GO:0000200; P:inactivation of MAPK activity involved in cell wall biogenesis; IMP:SGD.::GO:0000173; P:inactivation of MAPK activity involved in osmosensory signaling pathway; IGI:SGD.::GO:0032880; P:regulation of protein localization; IMP:SGD.::GO:0043937; P:regulation of sporulation; IGI:SGD.
3P23471    2315   PTPRZ_HUMAN Receptor-type tyrosine-protein ph...1170.54     38.1     30     44GO:0005887; C:integral to plasma membrane; TAS:ProtInc.
GO:0008330; F:protein tyrosine/threonine phosphatase activity; NAS:UniProtKB.::GO:0005001; F:transmembrane receptor protein tyrosine phosphatase activity; TAS:ProtInc.
GO:0007417; P:central nervous system development; TAS:ProtInc.
4Q62656    2316   PTPRZ_RAT Receptor-type tyrosine-protein phos...1170.54     38.1     30     44GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.
5P29350    595   PTN6_HUMAN Tyrosine-protein phosphatase non-r...3471e-17     91.3     26     37GO:0005829; C:cytosol; TAS:Reactome.::GO:0016020; C:membrane; TAS:ProtInc.::GO:0005634; C:nucleus; IDA:BHF-UCL.
GO:0019901; F:protein kinase binding; IPI:UniProtKB.::GO:0005001; F:transmembrane receptor protein tyrosine phosphatase activity; IDA:UniProtKB.
GO:0006915; P:apoptotic process; TAS:ProtInc.::GO:0007596; P:blood coagulation; TAS:Reactome.::GO:0030154; P:cell differentiation; IDA:UniProtKB.::GO:0008283; P:cell proliferation; IDA:UniProtKB.::GO:0007186; P:G-protein coupled receptor signaling pathway; TAS:ProtInc.::GO:0060333; P:interferon-gamma-mediated signaling pathway; TAS:Reactome.::GO:0060397; P:JAK-STAT cascade involved in growth hormone signaling pathway; TAS:Reactome.::GO:0050900; P:leukocyte migration; TAS:Reactome.::GO:0050732; P:negative regulation of peptidyl-tyrosine phosphorylation; IMP:BHF-UCL.::GO:0018108; P:peptidyl-tyrosine phosphorylation; IDA:UniProtKB.::GO:0008284; P:positive regulation of cell proliferation; IMP:BHF-UCL.::GO:0014068; P:positive regulation of phosphatidylinositol 3-kinase cascade; IMP:BHF-UCL.::GO:0070372; P:regulation of ERK1 and ERK2 cascade; IDA:UniProtKB.::GO:2000045; P:regulation of G1/S transition of mitotic cell cycle; IMP:BHF-UCL.::GO:0060334; P:regulation of interferon-gamma-mediated signaling pathway; TAS:Reactome.::GO:0060338; P:regulation of type I interferon-mediated signaling pathway; TAS:Reactome.::GO:0031295; P:T cell costimulation; TAS:Reactome.::GO:0060337; P:type I interferon-mediated signaling pathway; TAS:Reactome.
6P29351    595   PTN6_MOUSE Tyrosine-protein phosphatase non-r...3474e-17     89.7     26     38GO:0042105; C:alpha-beta T cell receptor complex; IDA:MGI.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0001784; F:phosphotyrosine binding; IPI:MGI.::GO:0042169; F:SH2 domain binding; IDA:MGI.::GO:0017124; F:SH3 domain binding; IDA:MGI.::GO:0005001; F:transmembrane receptor protein tyrosine phosphatase activity; ISS:UniProtKB.
GO:0050853; P:B cell receptor signaling pathway; IMP:MGI.::GO:0030154; P:cell differentiation; ISS:UniProtKB.::GO:0008283; P:cell proliferation; ISS:UniProtKB.::GO:0019221; P:cytokine-mediated signaling pathway; TAS:MGI.::GO:0035556; P:intracellular signal transduction; IDA:MGI.::GO:0042267; P:natural killer cell mediated cytotoxicity; IMP:MGI.::GO:0002924; P:negative regulation of humoral immune response mediated by circulating immunoglobulin; IMP:MGI.::GO:0043407; P:negative regulation of MAP kinase activity; IMP:MGI.::GO:0043409; P:negative regulation of MAPK cascade; IMP:MGI.::GO:0050732; P:negative regulation of peptidyl-tyrosine phosphorylation; IMP:MGI.::GO:0042130; P:negative regulation of T cell proliferation; IMP:MGI.::GO:0050860; P:negative regulation of T cell receptor signaling pathway; IMP:MGI.::GO:0045577; P:regulation of B cell differentiation; IMP:MGI.::GO:0070372; P:regulation of ERK1 and ERK2 cascade; ISS:UniProtKB.
7P81718    613   PTN6_RAT Tyrosine-protein phosphatase non-rec...3446e-17     89     28     39GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0046703; F:natural killer cell lectin-like receptor binding; IPI:RGD.::GO:0005001; F:transmembrane receptor protein tyrosine phosphatase activity; ISS:UniProtKB.
GO:0030154; P:cell differentiation; ISS:UniProtKB.::GO:0008283; P:cell proliferation; ISS:UniProtKB.::GO:0070372; P:regulation of ERK1 and ERK2 cascade; ISS:UniProtKB.::GO:0009611; P:response to wounding; IEP:RGD.
8P54637    990   PTP3_DICDI Tyrosine-protein phosphatase 3 OS=...3514e-16     87     25     41GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.
GO:0007243; P:intracellular protein kinase cascade; IMP:dictyBase.::GO:0034504; P:protein localization to nucleus; IMP:dictyBase.::GO:0006970; P:response to osmotic stress; IMP:dictyBase.::GO:0042501; P:serine phosphorylation of STAT protein; IMP:dictyBase.
9P23470    1445   PTPRG_HUMAN Receptor-type tyrosine-protein ph...1171.2     36.6     26     42GO:0005887; C:integral to plasma membrane; TAS:ProtInc.
GO:0042802; F:identical protein binding; IPI:UniProtKB.::GO:0005001; F:transmembrane receptor protein tyrosine phosphatase activity; TAS:ProtInc.
GO:0007169; P:transmembrane receptor protein tyrosine kinase signaling pathway; TAS:ProtInc.
10P34137    522   PTP1_DICDI Tyrosine-protein phosphatase 1 OS=...2945e-16     85.9     26     40GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.
11Q05909    1442   PTPRG_MOUSE Receptor-type tyrosine-protein ph...1171     37     26     42GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0042802; F:identical protein binding; ISS:UniProtKB.::GO:0004725; F:protein tyrosine phosphatase activity; ISS:UniProtKB.
12O82656    340   PTP1_ARATH Protein-tyrosine-phosphatase PTP1 ...1200.00006     50.1     26     46GO:0005737; C:cytoplasm; IDA:TAIR.::GO:0005634; C:nucleus; IDA:TAIR.::GO:0005886; C:plasma membrane; IDA:TAIR.
GO:0004725; F:protein tyrosine phosphatase activity; IEA:InterPro.
GO:0007243; P:intracellular protein kinase cascade; TAS:TAIR.
13Q63259    983   PTPRN_RAT Receptor-type tyrosine-protein phos...3410.00000000000001     82     24     38GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005624; C:membrane fraction; IDA:RGD.
GO:0051020; F:GTPase binding; IPI:RGD.::GO:0004725; F:protein tyrosine phosphatase activity; IEA:InterPro.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW.
GO:0019221; P:cytokine-mediated signaling pathway; IDA:RGD.::GO:0051591; P:response to cAMP; IEP:RGD.::GO:0043627; P:response to estrogen stimulus; IEP:RGD.::GO:0009749; P:response to glucose stimulus; IEP:RGD.::GO:0032868; P:response to insulin stimulus; IEP:RGD.::GO:0000302; P:response to reactive oxygen species; ISS:UniProtKB.::GO:0019932; P:second-messenger-mediated signaling; TAS:RGD.
14Q60673    979   PTPRN_MOUSE Receptor-type tyrosine-protein ph...3410.00000000000002     82     24     38GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005624; C:membrane fraction; TAS:MGI.::GO:0005886; C:plasma membrane; TAS:MGI.
GO:0004725; F:protein tyrosine phosphatase activity; TAS:MGI.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW.
GO:0000302; P:response to reactive oxygen species; ISS:UniProtKB.::GO:0007185; P:transmembrane receptor protein tyrosine phosphatase signaling pathway; TAS:MGI.
15Q63475    1004   PTPR2_RAT Receptor-type tyrosine-protein phos...790.0009     47     38     48GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005624; C:membrane fraction; IDA:RGD.::GO:0030141; C:secretory granule; IDA:RGD.::GO:0043195; C:terminal button; IDA:RGD.::GO:0030658; C:transport vesicle membrane; IEA:UniProtKB-SubCell.
GO:0005515; F:protein binding; IPI:RGD.::GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW.
GO:0034260; P:negative regulation of GTPase activity; IDA:RGD.
16Q62136    1176   PTN21_MOUSE Tyrosine-protein phosphatase non-...4000.000000000003     74.7     23     40GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.
GO:0005488; F:binding; IEA:InterPro.::GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.
17Q62728    1175   PTN21_RAT Tyrosine-protein phosphatase non-re...4000.000000000003     74.3     23     39GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.
GO:0005488; F:binding; IEA:InterPro.::GO:0004725; F:protein tyrosine phosphatase activity; IDA:RGD.
GO:0007010; P:cytoskeleton organization; NAS:RGD.
18Q9Y2R2    807   PTN22_HUMAN Tyrosine-protein phosphatase non-...1190.00000002     62     34     47GO:0009898; C:internal side of plasma membrane; IDA:UniProtKB.::GO:0005634; C:nucleus; IDA:UniProtKB.::GO:0048471; C:perinuclear region of cytoplasm; IDA:BHF-UCL.
GO:0019900; F:kinase binding; ISS:BHF-UCL.::GO:0004725; F:protein tyrosine phosphatase activity; IDA:UniProtKB.::GO:0017124; F:SH3 domain binding; ISS:BHF-UCL.
GO:0050868; P:negative regulation of T cell activation; IMP:BHF-UCL.::GO:0050860; P:negative regulation of T cell receptor signaling pathway; IDA:UniProtKB.::GO:0035644; P:phosphoanandamide dephosphorylation; ISS:BHF-UCL.::GO:0050855; P:regulation of B cell receptor signaling pathway; NAS:BHF-UCL.::GO:0045088; P:regulation of innate immune response; IC:BHF-UCL.::GO:0032817; P:regulation of natural killer cell proliferation; IDA:BHF-UCL.::GO:0030217; P:T cell differentiation; ISS:BHF-UCL.
19Q99952    460   PTN18_HUMAN Tyrosine-protein phosphatase non-...1390.00000000007     69.3     29     48GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0004726; F:non-membrane spanning protein tyrosine phosphatase activity; TAS:ProtInc.
20P80560    1001   PTPR2_MOUSE Receptor-type tyrosine-protein ph...790.001     47     38     48GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0030141; C:secretory granule; IDA:MGI.::GO:0030658; C:transport vesicle membrane; IEA:UniProtKB-SubCell.
GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW.
21Q92932    1015   PTPR2_HUMAN Receptor-type tyrosine-protein ph...790.0009     47     38     48GO:0005887; C:integral to plasma membrane; TAS:ProtInc.::GO:0030658; C:transport vesicle membrane; IEA:UniProtKB-SubCell.
GO:0005001; F:transmembrane receptor protein tyrosine phosphatase activity; TAS:ProtInc.
22O02695    1013   PTPR2_MACNE Receptor-type tyrosine-protein ph...790.0007     47.4     38     48GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0030658; C:transport vesicle membrane; IEA:UniProtKB-SubCell.
GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW.
23O55082    426   PTN20_MOUSE Tyrosine-protein phosphatase non-...1250.00002     51.6     29     43GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.
24P29352    802   PTN22_MOUSE Tyrosine-protein phosphatase non-...1190.0000002     58.5     34     46GO:0009898; C:internal side of plasma membrane; IDA:UniProtKB.::GO:0005634; C:nucleus; IDA:UniProtKB.::GO:0048471; C:perinuclear region of cytoplasm; ISS:BHF-UCL.
GO:0019900; F:kinase binding; IPI:BHF-UCL.::GO:0004725; F:protein tyrosine phosphatase activity; ISS:UniProtKB.::GO:0017124; F:SH3 domain binding; IPI:BHF-UCL.
GO:0050868; P:negative regulation of T cell activation; IMP:BHF-UCL.::GO:0050860; P:negative regulation of T cell receptor signaling pathway; ISS:UniProtKB.::GO:0035644; P:phosphoanandamide dephosphorylation; IDA:BHF-UCL.::GO:0032817; P:regulation of natural killer cell proliferation; ISS:BHF-UCL.::GO:0030217; P:T cell differentiation; IMP:MGI.::GO:0050852; P:T cell receptor signaling pathway; IMP:MGI.
25Q9WU22    926   PTN4_MOUSE Tyrosine-protein phosphatase non-r...1200.00000000007     70.1     33     49GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0008092; F:cytoskeletal protein binding; IEA:InterPro.::GO:0004726; F:non-membrane spanning protein tyrosine phosphatase activity; IDA:MGI.
26Q16825    1174   PTN21_HUMAN Tyrosine-protein phosphatase non-...4020.0000000001     69.3     23     39GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.::GO:0005856; C:cytoskeleton; TAS:ProtInc.
GO:0005488; F:binding; IEA:InterPro.::GO:0004725; F:protein tyrosine phosphatase activity; TAS:ProtInc.
27A1L1L3    421   PTN20_RAT Tyrosine-protein phosphatase non-re...1450.00004     50.4     26     39GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.
28Q4JDL3    420   PTN20_HUMAN Tyrosine-protein phosphatase non-...1330.0002     48.5     26     41GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.
29Q61152    453   PTN18_MOUSE Tyrosine-protein phosphatase non-...1630.00000004     60.5     27     42GO:0005737; C:cytoplasm; IDA:MGI.::GO:0005634; C:nucleus; IDA:MGI.
GO:0004726; F:non-membrane spanning protein tyrosine phosphatase activity; IDA:MGI.::GO:0005515; F:protein binding; IPI:MGI.
30P29074    926   PTN4_HUMAN Tyrosine-protein phosphatase non-r...1490.000003     55.1     27     46GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.::GO:0009898; C:internal side of plasma membrane; IDA:UniProtKB.
GO:0008092; F:cytoskeletal protein binding; IEA:InterPro.::GO:0004726; F:non-membrane spanning protein tyrosine phosphatase activity; TAS:ProtInc.
31Q05209    780   PTN12_HUMAN Tyrosine-protein phosphatase non-...1170.000000006     63.5     34     46GO:0030054; C:cell junction; IEA:UniProtKB-KW.::GO:0042995; C:cell projection; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IDA:HPA.::GO:0002102; C:podosome; IEA:UniProtKB-SubCell.::GO:0005625; C:soluble fraction; TAS:ProtInc.
GO:0004726; F:non-membrane spanning protein tyrosine phosphatase activity; TAS:ProtInc.::GO:0017124; F:SH3 domain binding; IPI:UniProtKB.
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