Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YER075C
Length:
928
Number of sequences:
5887
Description:
YER075C PTP3 SGDID:S000000877, Chr V from 311199-308413, Genome Release 64-1-1, reverse complement, Verified ORF, "Phosphotyrosine-specific protein phosphatase involved in the inactivation of mitogen-activated protein kinase (MAPK) during osmolarity sensing; dephosporylates Hog1p MAPK and regulates its localization; localized to the cytoplasm"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
121P35233    416   PTN2_RAT Tyrosine-protein phosphatase non-rec...1170.05     40.8     26     41GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.::GO:0031965; C:nuclear membrane; IEA:UniProtKB-SubCell.
GO:0003677; F:DNA binding; TAS:RGD.::GO:0004726; F:non-membrane spanning protein tyrosine phosphatase activity; IDA:RGD.
122Q06180    406   PTN2_MOUSE Tyrosine-protein phosphatase non-r...1170.12     39.7     26     41GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0008286; P:insulin receptor signaling pathway; IMP:MGI.
123P27574    550   PYP1_SCHPO Tyrosine-protein phosphatase 1 OS=...460.005     44.3     37     74GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IDA:PomBase.
GO:0004725; F:protein tyrosine phosphatase activity; TAS:PomBase.
GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0045930; P:negative regulation of mitotic cell cycle; IMP:PomBase.::GO:0032873; P:negative regulation of stress-activated MAPK cascade; TAS:PomBase.::GO:0045014; P:negative regulation of transcription by glucose; IMP:PomBase.
124O88902    1499   PTN23_RAT Tyrosine-protein phosphatase non-re...1430.0002     48.9     24     41GO:0005929; C:cilium; IEA:UniProtKB-KW.::GO:0016023; C:cytoplasmic membrane-bounded vesicle; IEA:UniProtKB-SubCell.::GO:0005768; C:endosome; ISS:UniProtKB.::GO:0005932; C:microtubule basal body; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.
GO:0060271; P:cilium morphogenesis; ISS:UniProtKB.
125P17706    415   PTN2_HUMAN Tyrosine-protein phosphatase non-r...1170.12     39.7     26     41GO:0005783; C:endoplasmic reticulum; IDA:UniProtKB.::GO:0005654; C:nucleoplasm; TAS:Reactome.
GO:0005515; F:protein binding; IPI:IntAct.::GO:0004725; F:protein tyrosine phosphatase activity; IEA:InterPro.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW.
GO:0060333; P:interferon-gamma-mediated signaling pathway; TAS:Reactome.::GO:0060334; P:regulation of interferon-gamma-mediated signaling pathway; TAS:Reactome.
126P35821    432   PTN1_MOUSE Tyrosine-protein phosphatase non-r...1380.001     45.8     27     43GO:0005829; C:cytosol; TAS:Reactome.::GO:0005769; C:early endosome; ISS:UniProtKB.::GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
GO:0004725; F:protein tyrosine phosphatase activity; ISS:UniProtKB.
GO:0031532; P:actin cytoskeleton reorganization; ISS:UniProtKB.::GO:0030968; P:endoplasmic reticulum unfolded protein response; ISS:UniProtKB.::GO:0008286; P:insulin receptor signaling pathway; IMP:MGI.::GO:0030100; P:regulation of endocytosis; ISS:UniProtKB.
127P20417    432   PTN1_RAT Tyrosine-protein phosphatase non-rec...1370.0008     46.6     26     43GO:0031225; C:anchored to membrane; NAS:RGD.::GO:0031410; C:cytoplasmic vesicle; IDA:RGD.::GO:0005829; C:cytosol; IDA:RGD.::GO:0005769; C:early endosome; ISS:UniProtKB.::GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.::GO:0005626; C:insoluble fraction; IDA:RGD.
GO:0005158; F:insulin receptor binding; IDA:RGD.::GO:0004725; F:protein tyrosine phosphatase activity; IDA:RGD.
GO:0031532; P:actin cytoskeleton reorganization; ISS:UniProtKB.::GO:0030968; P:endoplasmic reticulum unfolded protein response; ISS:UniProtKB.::GO:0030100; P:regulation of endocytosis; ISS:UniProtKB.::GO:0046626; P:regulation of insulin receptor signaling pathway; IMP:RGD.
128P18031    435   PTN1_HUMAN Tyrosine-protein phosphatase non-r...1370.0006     47     26     43GO:0005829; C:cytosol; TAS:Reactome.::GO:0005769; C:early endosome; IDA:UniProtKB.::GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
GO:0046875; F:ephrin receptor binding; IPI:UniProtKB.::GO:0019901; F:protein kinase binding; IPI:UniProtKB.::GO:0004725; F:protein tyrosine phosphatase activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IDA:UniProtKB.
GO:0031532; P:actin cytoskeleton reorganization; IMP:UniProtKB.::GO:0030968; P:endoplasmic reticulum unfolded protein response; IDA:UniProtKB.::GO:0060333; P:interferon-gamma-mediated signaling pathway; TAS:Reactome.::GO:0060397; P:JAK-STAT cascade involved in growth hormone signaling pathway; TAS:Reactome.::GO:0046627; P:negative regulation of insulin receptor signaling pathway; NAS:BHF-UCL.::GO:0030168; P:platelet activation; TAS:Reactome.::GO:0030100; P:regulation of endocytosis; IDA:UniProtKB.::GO:0060334; P:regulation of interferon-gamma-mediated signaling pathway; TAS:Reactome.::GO:0060338; P:regulation of type I interferon-mediated signaling pathway; TAS:Reactome.::GO:0060337; P:type I interferon-mediated signaling pathway; TAS:Reactome.
129Q6YI48    1434   PTPRU_CHICK Receptor-type tyrosine-protein ph...790.24     38.9     30     43GO:0030054; C:cell junction; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW.
GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.::GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.
130B3DK56    1444   PTPRU_DANRE Receptor-type tyrosine-protein ph...790.77     37.4     30     49GO:0030054; C:cell junction; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW.
GO:0007155; P:cell adhesion; IEA:UniProtKB-KW.::GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0001757; P:somite specification; IMP:ZFIN.
131Q92729    1446   PTPRU_HUMAN Receptor-type tyrosine-protein ph...800.23     39.3     30     48GO:0005911; C:cell-cell junction; IDA:UniProtKB.::GO:0005887; C:integral to plasma membrane; NAS:UniProtKB.
GO:0008013; F:beta-catenin binding; IPI:UniProtKB.::GO:0005001; F:transmembrane receptor protein tyrosine phosphatase activity; NAS:UniProtKB.
GO:0060070; P:canonical Wnt receptor signaling pathway; IDA:UniProtKB.::GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0030336; P:negative regulation of cell migration; IDA:UniProtKB.::GO:0008285; P:negative regulation of cell proliferation; IDA:UniProtKB.::GO:0034394; P:protein localization at cell surface; IDA:UniProtKB.::GO:0007185; P:transmembrane receptor protein tyrosine phosphatase signaling pathway; NAS:UniProtKB.
132B1AUH1    1446   PTPRU_MOUSE Receptor-type tyrosine-protein ph...800.26     38.9     30     48GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.::GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
GO:0008013; F:beta-catenin binding; IPI:MGI.::GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.::GO:0004872; F:receptor activity; IEA:UniProtKB-KW.
GO:0030154; P:cell differentiation; IEA:UniProtKB-KW.::GO:0034109; P:homotypic cell-cell adhesion; IDA:MGI.
133Q9BY84    665   DUS16_HUMAN Dual specificity protein phosphat...1440.002     45.4     31     52GO:0016023; C:cytoplasmic membrane-bounded vesicle; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; TAS:UniProtKB.
GO:0017017; F:MAP kinase tyrosine/serine/threonine phosphatase activity; IBA:RefGenome.::GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.
GO:0045204; P:MAPK export from nucleus; TAS:UniProtKB.::GO:0045209; P:MAPK phosphatase export from nucleus, leptomycin B sensitive; TAS:UniProtKB.
134Q05922    318   DUS2_MOUSE Dual specificity protein phosphata...1390.024     41.6     29     43GO:0005654; C:nucleoplasm; IBA:RefGenome.
GO:0017017; F:MAP kinase tyrosine/serine/threonine phosphatase activity; IBA:RefGenome.::GO:0051019; F:mitogen-activated protein kinase binding; IPI:MGI.::GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.
GO:0001706; P:endoderm formation; IBA:RefGenome.::GO:0042981; P:regulation of apoptotic process; IBA:RefGenome.
135Q62767    395   DUS4_RAT Dual specificity protein phosphatase...1290.029     41.6     29     48GO:0005654; C:nucleoplasm; IBA:RefGenome.::GO:0005625; C:soluble fraction; IDA:RGD.
GO:0017017; F:MAP kinase tyrosine/serine/threonine phosphatase activity; IDA:RGD.::GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.::GO:0008330; F:protein tyrosine/threonine phosphatase activity; IDA:RGD.
GO:0001706; P:endoderm formation; IBA:RefGenome.::GO:0010033; P:response to organic substance; IEP:RGD.
136Q8BFV3    398   DUS4_MOUSE Dual specificity protein phosphata...1290.03     41.6     29     48GO:0005654; C:nucleoplasm; IBA:RefGenome.
GO:0017017; F:MAP kinase tyrosine/serine/threonine phosphatase activity; IBA:RefGenome.::GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.
GO:0001706; P:endoderm formation; IBA:RefGenome.
137Q13115    394   DUS4_HUMAN Dual specificity protein phosphata...1250.041     41.2     29     49GO:0005654; C:nucleoplasm; TAS:Reactome.
GO:0017017; F:MAP kinase tyrosine/serine/threonine phosphatase activity; IBA:RefGenome.::GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.::GO:0008330; F:protein tyrosine/threonine phosphatase activity; TAS:ProtInc.
GO:0001706; P:endoderm formation; IBA:RefGenome.::GO:0045087; P:innate immune response; TAS:Reactome.::GO:0002755; P:MyD88-dependent toll-like receptor signaling pathway; TAS:Reactome.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0051403; P:stress-activated MAPK cascade; TAS:Reactome.::GO:0008063; P:Toll signaling pathway; TAS:Reactome.::GO:0034130; P:toll-like receptor 1 signaling pathway; TAS:Reactome.::GO:0034134; P:toll-like receptor 2 signaling pathway; TAS:Reactome.::GO:0034138; P:toll-like receptor 3 signaling pathway; TAS:Reactome.::GO:0034142; P:toll-like receptor 4 signaling pathway; TAS:Reactome.::GO:0035666; P:TRIF-dependent toll-like receptor signaling pathway; TAS:Reactome.
138Q5I142    261   PTPH5_MDBVW Tyrosine phosphatase-like protein...1550.053     40     26     45
GO:0004725; F:protein tyrosine phosphatase activity; IEA:InterPro.
139Q5I127    132   PTPN2_MDBVW Tyrosine phosphatase-like protein...410.073     38.1     39     59
GO:0004725; F:protein tyrosine phosphatase activity; IEA:InterPro.
140Q9PW71    375   DUS4_CHICK Dual specificity protein phosphata...1550.11     39.7     23     43GO:0005654; C:nucleoplasm; IBA:RefGenome.
GO:0017017; F:MAP kinase tyrosine/serine/threonine phosphatase activity; IBA:RefGenome.::GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.
GO:0001706; P:endoderm formation; IBA:RefGenome.
141Q16829    419   DUS7_HUMAN Dual specificity protein phosphata...1400.17     39.3     23     41GO:0005829; C:cytosol; IDA:UniProtKB.::GO:0005654; C:nucleoplasm; TAS:Reactome.
GO:0017017; F:MAP kinase tyrosine/serine/threonine phosphatase activity; IDA:UniProtKB.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.
GO:0045087; P:innate immune response; TAS:Reactome.::GO:0002755; P:MyD88-dependent toll-like receptor signaling pathway; TAS:Reactome.::GO:0048011; P:nerve growth factor receptor signaling pathway; TAS:Reactome.::GO:0051403; P:stress-activated MAPK cascade; TAS:Reactome.::GO:0008063; P:Toll signaling pathway; TAS:Reactome.::GO:0034130; P:toll-like receptor 1 signaling pathway; TAS:Reactome.::GO:0034134; P:toll-like receptor 2 signaling pathway; TAS:Reactome.::GO:0034138; P:toll-like receptor 3 signaling pathway; TAS:Reactome.::GO:0034142; P:toll-like receptor 4 signaling pathway; TAS:Reactome.::GO:0035666; P:TRIF-dependent toll-like receptor signaling pathway; TAS:Reactome.
142Q91Z46    422   DUS7_MOUSE Dual specificity protein phosphata...1400.18     38.9     23     41GO:0005829; C:cytosol; IBA:RefGenome.
GO:0017017; F:MAP kinase tyrosine/serine/threonine phosphatase activity; IBA:RefGenome.::GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.
143Q9UNH5    594   CC14A_HUMAN Dual specificity protein phosphat...1330.41     38.1     26     41GO:0005813; C:centrosome; IDA:UniProtKB.::GO:0005634; C:nucleus; IDA:HPA.::GO:0005819; C:spindle; IEA:UniProtKB-SubCell.
GO:0005515; F:protein binding; IPI:HGNC.::GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.::GO:0008138; F:protein tyrosine/serine/threonine phosphatase activity; IEA:InterPro.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0008283; P:cell proliferation; TAS:ProtInc.
144P37421    348   RFAF_SALTY ADP-heptose--LPS heptosyltransfera...850.42     37.7     28     52
GO:0016757; F:transferase activity, transferring glycosyl groups; IEA:UniProtKB-KW.
GO:0009103; P:lipopolysaccharide biosynthetic process; IEA:UniProtKB-KW.
145Q5I137    299   PTPJ4_MDBVW Probable tyrosine phosphatase pro...980.59     37     28     41
GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.
146P37692    348   RFAF_ECOLI ADP-heptose--LPS heptosyltransfera...860.87     36.6     27     51
GO:0016757; F:transferase activity, transferring glycosyl groups; IDA:EcoCyc.
GO:0009244; P:lipopolysaccharide core region biosynthetic process; IDA:EcoCyc.
147Q9JLY7    198   DUS14_MOUSE Dual specificity protein phosphat...1202.1     35     25     46GO:0005737; C:cytoplasm; ISS:MGI.::GO:0005634; C:nucleus; ISS:MGI.
GO:0017017; F:MAP kinase tyrosine/serine/threonine phosphatase activity; IEA:InterPro.::GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.
148P74873    543   SPTP_SALTY Secreted effector protein sptP OS=...722.3     35.4     36     50GO:0005615; C:extracellular space; IEA:InterPro.::GO:0030430; C:host cell cytoplasm; IEA:UniProtKB-SubCell.
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.
GO:0009405; P:pathogenesis; IEA:UniProtKB-KW.
149Q5PEA9    543   SPTP_SALPA Secreted effector protein sptP OS=...722.8     35.4     36     50GO:0005615; C:extracellular space; IEA:InterPro.::GO:0030430; C:host cell cytoplasm; IEA:UniProtKB-SubCell.
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.
GO:0009405; P:pathogenesis; IEA:UniProtKB-KW.
150P74851    543   SPTP_SALTI Secreted effector protein sptP OS=...723.3     35     36     50GO:0005615; C:extracellular space; IEA:InterPro.::GO:0030430; C:host cell cytoplasm; IEA:UniProtKB-SubCell.
GO:0005096; F:GTPase activator activity; IEA:UniProtKB-KW.::GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.
GO:0009405; P:pathogenesis; IEA:UniProtKB-KW.
151Q9VVW5    411   DUSK3_DROME Dual specificity protein phosphat...403.5     35     35     70GO:0005829; C:cytosol; IBA:RefGenome.
GO:0017017; F:MAP kinase tyrosine/serine/threonine phosphatase activity; IBA:RefGenome.::GO:0004725; F:protein tyrosine phosphatase activity; IEA:EC.
GO:0016337; P:cell-cell adhesion; IMP:FlyBase.::GO:0007474; P:imaginal disc-derived wing vein specification; IMP:FlyBase.::GO:0035160; P:maintenance of epithelial integrity, open tracheal system; IMP:FlyBase.::GO:0002385; P:mucosal immune response; IMP:FlyBase.::GO:0007428; P:primary branching, open tracheal system; IMP:FlyBase.::GO:0042127; P:regulation of cell proliferation; IGI:FlyBase.
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