Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YER070W
Length:
888
Number of sequences:
5887
Description:
YER070W RNR1 SGDID:S000000872, Chr V from 298950-301616, Genome Release 64-1-1, Verified ORF, "Major isoform of the large subunit of ribonucleotide-diphosphate reductase; the RNR complex catalyzes rate-limiting step in dNTP synthesis, regulated by DNA replication and DNA damage checkpoint pathways via localization of small subunits"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
1P21524    888   RIR1_YEAST Ribonucleoside-diphosphate reducta...8880     1861     100     100GO:0005971; C:ribonucleoside-diphosphate reductase complex; IDA:SGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004748; F:ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor; ISS:UniProtKB.
GO:0009263; P:deoxyribonucleotide biosynthetic process; ISS:UniProtKB.::GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
2P21672    869   RIR3_YEAST Ribonucleoside-diphosphate reducta...8880     1532     80     90GO:0005739; C:mitochondrion; IDA:SGD.::GO:0005971; C:ribonucleoside-diphosphate reductase complex; TAS:SGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004748; F:ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor; IDA:SGD.
GO:0009263; P:deoxyribonucleotide biosynthetic process; IDA:SGD.::GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
3Q9UW15    929   RIR1_NEUCR Ribonucleoside-diphosphate reducta...9400     1232     63     77GO:0005971; C:ribonucleoside-diphosphate reductase complex; IEA:InterPro.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004748; F:ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor; ISS:UniProtKB.
GO:0009263; P:deoxyribonucleotide biosynthetic process; ISS:UniProtKB.::GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
4P36602    811   RIR1_SCHPO Ribonucleoside-diphosphate reducta...8890     1225     66     79GO:0005829; C:cytosol; IDA:PomBase.::GO:0005971; C:ribonucleoside-diphosphate reductase complex; TAS:PomBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:PomBase.::GO:0004748; F:ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor; ISS:UniProtKB.
GO:0006260; P:DNA replication; IEA:UniProtKB-KW.::GO:0009216; P:purine deoxyribonucleoside triphosphate biosynthetic process; IC:PomBase.::GO:0042278; P:purine nucleoside metabolic process; IC:PomBase.::GO:0009212; P:pyrimidine deoxyribonucleoside triphosphate biosynthetic process; IC:PomBase.::GO:0006213; P:pyrimidine nucleoside metabolic process; IC:PomBase.::GO:0090329; P:regulation of DNA-dependent DNA replication; IMP:PomBase.::GO:0007090; P:regulation of S phase of mitotic cell cycle; IMP:PomBase.
5Q03604    788   RIR1_CAEEL Ribonucleoside-diphosphate reducta...7580     1106     68     82GO:0005971; C:ribonucleoside-diphosphate reductase complex; IEA:InterPro.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004748; F:ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor; ISS:UniProtKB.
GO:0006915; P:apoptotic process; IMP:WormBase.::GO:0009263; P:deoxyribonucleotide biosynthetic process; ISS:UniProtKB.::GO:0006260; P:DNA replication; IEA:UniProtKB-KW.::GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0040007; P:growth; IMP:WormBase.::GO:0040035; P:hermaphrodite genitalia development; IMP:WormBase.::GO:0040011; P:locomotion; IMP:WormBase.::GO:0002119; P:nematode larval development; IMP:WormBase.::GO:0040017; P:positive regulation of locomotion; IMP:WormBase.
6P79732    794   RIR1_DANRE Ribonucleoside-diphosphate reducta...7600     1102     67     83GO:0005971; C:ribonucleoside-diphosphate reductase complex; IEA:InterPro.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004748; F:ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor; ISS:UniProtKB.
GO:0009263; P:deoxyribonucleotide biosynthetic process; ISS:UniProtKB.::GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
7P23921    792   RIR1_HUMAN Ribonucleoside-diphosphate reducta...7600     1099     67     84GO:0005829; C:cytosol; TAS:Reactome.::GO:0005654; C:nucleoplasm; TAS:Reactome.::GO:0005971; C:ribonucleoside-diphosphate reductase complex; NAS:UniProtKB.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004748; F:ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor; ISS:UniProtKB.
GO:0009263; P:deoxyribonucleotide biosynthetic process; ISS:UniProtKB.::GO:0006260; P:DNA replication; NAS:UniProtKB.::GO:0015949; P:nucleobase-containing small molecule interconversion; TAS:Reactome.
8P07742    792   RIR1_MOUSE Ribonucleoside-diphosphate reducta...7600     1096     67     83GO:0005971; C:ribonucleoside-diphosphate reductase complex; IEA:InterPro.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:MGI.::GO:0004748; F:ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor; IDA:UniProtKB.
GO:0009263; P:deoxyribonucleotide biosynthetic process; IDA:UniProtKB.::GO:0006260; P:DNA replication; IEA:UniProtKB-KW.::GO:0051290; P:protein heterotetramerization; IPI:UniProtKB.
9Q5R919    792   RIR1_PONAB Ribonucleoside-diphosphate reducta...7600     1095     67     83GO:0005971; C:ribonucleoside-diphosphate reductase complex; IEA:InterPro.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004748; F:ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor; ISS:UniProtKB.
GO:0009263; P:deoxyribonucleotide biosynthetic process; ISS:UniProtKB.::GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
10Q9SJ20    816   RIR1_ARATH Ribonucleoside-diphosphate reducta...7720     1093     64     81GO:0005971; C:ribonucleoside-diphosphate reductase complex; IEA:InterPro.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004748; F:ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor; ISS:UniProtKB.
GO:0009202; P:deoxyribonucleoside triphosphate biosynthetic process; IMP:TAIR.::GO:0006260; P:DNA replication; IMP:TAIR.::GO:0046686; P:response to cadmium ion; IEP:TAIR.
11P48591    812   RIR1_DROME Ribonucleoside-diphosphate reducta...7600     1090     65     82GO:0005971; C:ribonucleoside-diphosphate reductase complex; IEA:InterPro.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004748; F:ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor; ISS:UniProtKB.
GO:0006919; P:activation of cysteine-type endopeptidase activity involved in apoptotic process; IMP:FlyBase.::GO:0009263; P:deoxyribonucleotide biosynthetic process; ISS:UniProtKB.::GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
12P50648    806   RIR1_PLAF4 Ribonucleoside-diphosphate reducta...7680     1082     65     81GO:0005971; C:ribonucleoside-diphosphate reductase complex; IEA:InterPro.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004748; F:ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor; ISS:UniProtKB.
GO:0009263; P:deoxyribonucleotide biosynthetic process; ISS:UniProtKB.::GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
13Q54Q71    870   RIR1_DICDI Ribonucleoside-diphosphate reducta...7670     1046     63     80GO:0005971; C:ribonucleoside-diphosphate reductase complex; ISS:dictyBase.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:dictyBase.::GO:0004748; F:ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor; ISS:UniProtKB.
GO:0009186; P:deoxyribonucleoside diphosphate metabolic process; ISS:dictyBase.::GO:0009263; P:deoxyribonucleotide biosynthetic process; ISS:UniProtKB.::GO:0006260; P:DNA replication; ISS:dictyBase.
14P20503    771   RIR1_VACCC Ribonucleoside-diphosphate reducta...7590     1036     64     80GO:0005971; C:ribonucleoside-diphosphate reductase complex; IEA:InterPro.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004748; F:ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor; IEA:EC.
GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
15Q76RD8    771   RIR1_VACCA Ribonucleoside-diphosphate reducta...7590     1036     64     80GO:0005971; C:ribonucleoside-diphosphate reductase complex; IEA:InterPro.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004748; F:ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor; IEA:EC.
GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
16P12848    771   RIR1_VACCW Ribonucleoside-diphosphate reducta...7590     1035     64     80GO:0005971; C:ribonucleoside-diphosphate reductase complex; IEA:InterPro.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004748; F:ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor; IEA:EC.
GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
17O61065    803   RIR1_CRYPV Ribonucleoside-diphosphate reducta...7950     1031     61     77GO:0005971; C:ribonucleoside-diphosphate reductase complex; IEA:InterPro.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004748; F:ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor; ISS:UniProtKB.
GO:0009263; P:deoxyribonucleotide biosynthetic process; ISS:UniProtKB.::GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
18P32984    771   RIR1_VAR67 Ribonucleoside-diphosphate reducta...7590     1031     63     80GO:0005971; C:ribonucleoside-diphosphate reductase complex; IEA:InterPro.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004748; F:ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor; IEA:EC.
GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
19P50647    804   RIR1_PLAFG Ribonucleoside-diphosphate reducta...7680     1026     63     78GO:0005971; C:ribonucleoside-diphosphate reductase complex; IEA:InterPro.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004748; F:ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor; ISS:UniProtKB.
GO:0009263; P:deoxyribonucleotide biosynthetic process; ISS:UniProtKB.::GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
20O15909    838   RIR1_TRYBB Ribonucleoside-diphosphate reducta...7760     998     61     77GO:0005971; C:ribonucleoside-diphosphate reductase complex; IEA:InterPro.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004748; F:ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor; ISS:UniProtKB.
GO:0009263; P:deoxyribonucleotide biosynthetic process; ISS:UniProtKB.::GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
21Q8SR37    768   RIR1_ENCCU Ribonucleoside-diphosphate reducta...7750     855     51     72GO:0005971; C:ribonucleoside-diphosphate reductase complex; IEA:InterPro.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004748; F:ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor; ISS:UniProtKB.
GO:0009263; P:deoxyribonucleotide biosynthetic process; ISS:UniProtKB.::GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
22Q7T6Y8    881   RIR1_MIMIV Ribonucleoside-diphosphate reducta...8020     783     47     68GO:0005971; C:ribonucleoside-diphosphate reductase complex; IEA:InterPro.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004748; F:ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor; IEA:EC.
GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
23P42491    778   RIR1_ASFB7 Ribonucleoside-diphosphate reducta...7612e-163     503     40     58GO:0005971; C:ribonucleoside-diphosphate reductase complex; IEA:InterPro.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004748; F:ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor; IEA:EC.
GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
24P26685    779   RIR1_ASFM2 Ribonucleoside-diphosphate reducta...7656e-163     502     39     58GO:0005971; C:ribonucleoside-diphosphate reductase complex; IEA:InterPro.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004748; F:ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor; IEA:EC.
GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
25P0C8H8    778   RIR1_ASFP4 Ribonucleoside-diphosphate reducta...7631e-161     498     40     58GO:0005971; C:ribonucleoside-diphosphate reductase complex; IEA:InterPro.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004748; F:ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor; IEA:EC.
GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
26P0C8H9    778   RIR1_ASFWA Ribonucleoside-diphosphate reducta...7293e-161     497     41     59GO:0005971; C:ribonucleoside-diphosphate reductase complex; IEA:InterPro.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004748; F:ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor; IEA:EC.
GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
27P0C8H7    779   RIR1_ASFK5 Ribonucleoside-diphosphate reducta...7633e-161     497     39     57GO:0005971; C:ribonucleoside-diphosphate reductase complex; IEA:InterPro.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004748; F:ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor; IEA:EC.
GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
28Q9PL93    1047   RIR1_CHLMU Ribonucleoside-diphosphate reducta...7865e-156     491     38     55GO:0005971; C:ribonucleoside-diphosphate reductase complex; IEA:InterPro.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004748; F:ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor; IEA:EC.
GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
29O84834    1047   RIR1_CHLTR Ribonucleoside-diphosphate reducta...8437e-154     486     36     53GO:0005971; C:ribonucleoside-diphosphate reductase complex; IEA:InterPro.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004748; F:ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor; IEA:EC.
GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
30Q9Z6S5    1044   RIR1_CHLPN Ribonucleoside-diphosphate reducta...7855e-153     484     37     55GO:0005971; C:ribonucleoside-diphosphate reductase complex; IEA:InterPro.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0004748; F:ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor; IEA:EC.
GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
31Q6R7H4    835   RIR1_OSHVF Ribonucleoside-diphosphate reducta...7272e-137     436     35     55GO:0005971; C:ribonucleoside-diphosphate reductase complex; IEA:InterPro.
GO:0005524; F:ATP binding; IEA:InterPro.::GO:0004748; F:ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor; IEA:EC.
GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
records
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