Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YER068W
Length:
587
Number of sequences:
5887
Description:
YER068W MOT2 SGDID:S000000870, Chr V from 293050-294813, Genome Release 64-1-1, Verified ORF, "Subunit of the CCR4-NOT complex, which has roles in transcription regulation, mRNA degradation, and post-transcriptional modifications; with Ubc4p, ubiquitinates nascent polypeptide-associated complex subunits and histone demethyase Jhd2p"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
1P34909    587   NOT4_YEAST General negative regulator of tran...5870     1226     100     100GO:0030015; C:CCR4-NOT core complex; IPI:SGD.::GO:0005737; C:cytoplasm; IDA:SGD.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.::GO:0043565; F:sequence-specific DNA binding; IDA:SGD.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:SGD.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0031087; P:deadenylation-independent decapping of nuclear-transcribed mRNA; IMP:SGD.::GO:0032968; P:positive regulation of transcription elongation from RNA polymerase II promoter; IDA:SGD.::GO:0000209; P:protein polyubiquitination; IDA:SGD.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
2O95628    575   CNOT4_HUMAN CCR4-NOT transcription complex su...2451e-64     228     45     64GO:0005829; C:cytosol; TAS:Reactome.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0000289; P:nuclear-transcribed mRNA poly(A) tail shortening; TAS:Reactome.::GO:0051865; P:protein autoubiquitination; IDA:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
3Q8BT14    575   CNOT4_MOUSE CCR4-NOT transcription complex su...2451e-64     227     45     64GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0051865; P:protein autoubiquitination; ISS:UniProtKB.::GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
4Q09818    489   YAC4_SCHPO Putative general negative regulato...2522e-62     219     53     71GO:0030015; C:CCR4-NOT core complex; NAS:PomBase.::GO:0005829; C:cytosol; IDA:PomBase.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:PomBase.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0000289; P:nuclear-transcribed mRNA poly(A) tail shortening; ISS:PomBase.::GO:0006357; P:regulation of transcription from RNA polymerase II promoter; ISS:PomBase.::GO:0006368; P:transcription elongation from RNA polymerase II promoter; ISS:PomBase.
5Q5D7J2    497   TRIM5_PAPAN Tripartite motif-containing prote...930.048     40     33     43GO:0000932; C:cytoplasmic mRNA processing body; IEA:UniProtKB-SubCell.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
6Q8BZT2    735   SH3R2_MOUSE Putative E3 ubiquitin-protein lig...470.058     40     40     55
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008157; F:protein phosphatase 1 binding; ISS:UniProtKB.::GO:0004864; F:protein phosphatase inhibitor activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0010923; P:negative regulation of phosphatase activity; ISS:UniProtKB.
7Q498M5    735   SH3R2_RAT Putative E3 ubiquitin-protein ligas...470.058     40     40     55
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008157; F:protein phosphatase 1 binding; ISS:UniProtKB.::GO:0004864; F:protein phosphatase inhibitor activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0010923; P:negative regulation of phosphatase activity; ISS:UniProtKB.
8Q587N7    515   TRIM5_CHLAE Tripartite motif-containing prote...930.075     39.7     31     40GO:0000932; C:cytoplasmic mRNA processing body; IEA:UniProtKB-SubCell.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
9Q5C8U4    515   TRIM5_CERPY Tripartite motif-containing prote...880.081     39.7     32     41GO:0000932; C:cytoplasmic mRNA processing body; IEA:UniProtKB-SubCell.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
10Q5D7I3    495   TRIM5_ERYPA Tripartite motif-containing prote...930.094     39.3     31     40GO:0000932; C:cytoplasmic mRNA processing body; IEA:UniProtKB-SubCell.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
11Q8IWT3    2517   CUL9_HUMAN Cullin-9 OS=Homo sapiens (Human). ...810.11     39.3     33     48GO:0031461; C:cullin-RING ubiquitin ligase complex; IEA:InterPro.::GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0031625; F:ubiquitin protein ligase binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro.
12Q8TEC5    729   SH3R2_HUMAN Putative E3 ubiquitin-protein lig...470.11     39.3     38     55
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008157; F:protein phosphatase 1 binding; IDA:UniProtKB.::GO:0004864; F:protein phosphatase inhibitor activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0010923; P:negative regulation of phosphatase activity; IDA:UniProtKB.
13Q5C8U3    515   TRIM5_CERTA Tripartite motif-containing prote...880.12     38.9     32     40GO:0000932; C:cytoplasmic mRNA processing body; IEA:UniProtKB-SubCell.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
14P32849    1169   RAD5_YEAST DNA repair protein RAD5 OS=Sacchar...540.13     38.9     37     52GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0000790; C:nuclear chromatin; IDA:SGD.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0008094; F:DNA-dependent ATPase activity; IDA:SGD.::GO:0000400; F:four-way junction DNA binding; IDA:SGD.::GO:0009378; F:four-way junction helicase activity; IDA:SGD.::GO:0000403; F:Y-form DNA binding; IDA:SGD.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006302; P:double-strand break repair; IMP:SGD.::GO:0010994; P:free ubiquitin chain polymerization; IDA:SGD.::GO:0006301; P:postreplication repair; IDA:SGD.::GO:0000209; P:protein polyubiquitination; IDA:SGD.
15Q3ZEE5    493   TRIM5_HYLLA Tripartite motif-containing prote...860.25     37.7     31     42GO:0000932; C:cytoplasmic mRNA processing body; IEA:UniProtKB-SubCell.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
16Q5C8U1    494   TRIM5_SAGLB Tripartite motif-containing prote...870.28     37.7     33     41GO:0000932; C:cytoplasmic mRNA processing body; IEA:UniProtKB-SubCell.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
17Q9FNI6    1029   SM3L2_ARATH Putative SWI/SNF-related matrix-a...540.36     37.7     30     54GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; IEA:InterPro.::GO:0004386; F:helicase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0009294; P:DNA mediated transformation; IMP:TAIR.::GO:0000724; P:double-strand break repair via homologous recombination; IMP:TAIR.
18Q7YRV4    469   RO52_BOVIN E3 ubiquitin-protein ligase TRIM21...590.42     37     32     47GO:0000932; C:cytoplasmic mRNA processing body; IEA:UniProtKB-SubCell.::GO:0005634; C:nucleus; ISS:UniProtKB.
GO:0003677; F:DNA binding; IEA:UniProtKB-KW.::GO:0003723; F:RNA binding; IEA:UniProtKB-KW.::GO:0004842; F:ubiquitin-protein ligase activity; ISS:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0032088; P:negative regulation of NF-kappaB transcription factor activity; ISS:UniProtKB.::GO:0090086; P:negative regulation of protein deubiquitination; ISS:UniProtKB.::GO:0045787; P:positive regulation of cell cycle; ISS:UniProtKB.::GO:0051865; P:protein autoubiquitination; ISS:UniProtKB.::GO:0031648; P:protein destabilization; ISS:UniProtKB.::GO:0006513; P:protein monoubiquitination; ISS:UniProtKB.::GO:0000209; P:protein polyubiquitination; ISS:UniProtKB.
19Q14527    1009   HLTF_HUMAN Helicase-like transcription factor...790.46     37.4     24     47GO:0005634; C:nucleus; IDA:HPA.
GO:0005524; F:ATP binding; IEA:UniProtKB-KW.::GO:0003677; F:DNA binding; TAS:ProtInc.::GO:0004386; F:helicase activity; IEA:UniProtKB-KW.::GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:UniProtKB.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0016568; P:chromatin modification; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW.
20Q3UWZ0    467   TRI75_MOUSE Tripartite motif-containing prote...590.47     37     29     47GO:0005622; C:intracellular; IEA:InterPro.
GO:0008270; F:zinc ion binding; IEA:InterPro.
21Q8NHY2    731   RFWD2_HUMAN E3 ubiquitin-protein ligase RFWD2...780.49     37     31     50GO:0005813; C:centrosome; IDA:HPA.::GO:0005829; C:cytosol; TAS:Reactome.::GO:0005925; C:focal adhesion; IDA:HPA.::GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:IntAct.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0006977; P:DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest; TAS:Reactome.
22Q9DED4    166   CIRBB_XENLA Cold-inducible RNA-binding protei...690.49     35.8     32     57GO:0005737; C:cytoplasm; IDA:UniProtKB.::GO:0005654; C:nucleoplasm; IEA:UniProtKB-SubCell.
GO:0019899; F:enzyme binding; IPI:UniProtKB.::GO:0003730; F:mRNA 3'-UTR binding; ISS:UniProtKB.::GO:0000166; F:nucleotide binding; IEA:InterPro.
GO:0016477; P:cell migration; IMP:UniProtKB.::GO:0007369; P:gastrulation; IMP:UniProtKB.::GO:0048255; P:mRNA stabilization; IMP:UniProtKB.::GO:0060212; P:negative regulation of nuclear-transcribed mRNA poly(A) tail shortening; IMP:UniProtKB.::GO:0022008; P:neurogenesis; IMP:UniProtKB.::GO:0045727; P:positive regulation of translation; ISS:UniProtKB.::GO:0048793; P:pronephros development; ISS:UniProtKB.::GO:0009409; P:response to cold; ISS:UniProtKB.
23O93235    166   CIRBA_XENLA Cold-inducible RNA-binding protei...690.53     35.8     32     57GO:0010494; C:cytoplasmic stress granule; ISS:UniProtKB.::GO:0005654; C:nucleoplasm; IEA:UniProtKB-SubCell.
GO:0019899; F:enzyme binding; ISS:UniProtKB.::GO:0003730; F:mRNA 3'-UTR binding; ISS:UniProtKB.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0070181; F:SSU rRNA binding; ISS:UniProtKB.::GO:0030371; F:translation repressor activity; ISS:UniProtKB.
GO:0016477; P:cell migration; IMP:UniProtKB.::GO:0007369; P:gastrulation; IMP:UniProtKB.::GO:0072004; P:kidney field specification; IMP:UniProtKB.::GO:0048255; P:mRNA stabilization; ISS:UniProtKB.::GO:0060212; P:negative regulation of nuclear-transcribed mRNA poly(A) tail shortening; ISS:UniProtKB.::GO:0022008; P:neurogenesis; IMP:UniProtKB.::GO:0045727; P:positive regulation of translation; ISS:UniProtKB.::GO:0048793; P:pronephros development; IMP:UniProtKB.::GO:0009409; P:response to cold; IEP:UniProtKB.::GO:0009411; P:response to UV; ISS:UniProtKB.::GO:0034063; P:stress granule assembly; ISS:UniProtKB.
24Q9R1A8    733   RFWD2_MOUSE E3 ubiquitin-protein ligase RFWD2...780.56     37     31     50GO:0016607; C:nuclear speck; IEA:UniProtKB-SubCell.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0005515; F:protein binding; IPI:BHF-UCL.::GO:0008270; F:zinc ion binding; IEA:InterPro.
25P38748    585   ETP1_YEAST RING finger protein ETP1 OS=Saccha...470.58     37     38     47GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0008139; F:nuclear localization sequence binding; IDA:SGD.::GO:0043130; F:ubiquitin binding; IDA:SGD.::GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0045471; P:response to ethanol; IMP:SGD.
26Q1ACD5    494   TRIM5_SAGOE Tripartite motif-containing prote...660.59     36.6     35     45GO:0000932; C:cytoplasmic mRNA processing body; IEA:UniProtKB-SubCell.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
27Q9SZL9    1111   CSLD4_ARATH Cellulose synthase-like protein D...370.63     37     32     59GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.::GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
GO:0016760; F:cellulose synthase (UDP-forming) activity; IEA:InterPro.
GO:0007047; P:cellular cell wall organization; IEA:UniProtKB-KW.::GO:0030244; P:cellulose biosynthetic process; IEA:InterPro.::GO:0009846; P:pollen germination; IMP:TAIR.
28Q1ACD7    494   TRIM5_NOMLE Tripartite motif-containing prote...870.74     36.2     32     43GO:0000932; C:cytoplasmic mRNA processing body; IEA:UniProtKB-SubCell.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
29Q1ACD6    494   TRIM5_HYLSY Tripartite motif-containing prote...870.76     36.2     32     43GO:0000932; C:cytoplasmic mRNA processing body; IEA:UniProtKB-SubCell.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
30Q5C8T6    493   TRIM5_GORGO Tripartite motif-containing prote...660.8     36.2     32     44GO:0000932; C:cytoplasmic mRNA processing body; IEA:UniProtKB-SubCell.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
31Q5D7I1    547   TRIM5_ATEGE Tripartite motif-containing prote...920.8     36.2     30     40GO:0000932; C:cytoplasmic mRNA processing body; IEA:UniProtKB-SubCell.
GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0008270; F:zinc ion binding; IEA:InterPro.
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