| rec. | Subject | Hit Length | Description | Align.Len | E value | Bit score | % ident. | % pos. | GO associations |
1 | P40042 | 185 | RRT13_YEAST Regulator of rDNA transcription p... | 185 | 3e-133 | 377 | 100 | 100 | | | | | | | | | | | | | | | | | | | | | GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.::GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. | 2 | P07834 | 779 | CDC4_YEAST Cell division control protein 4 OS... | 107 | 1.6 | 32.7 | 26 | 43 | GO:0016363; C:nuclear matrix; IDA:SGD.::GO:0043224; C:nuclear SCF ubiquitin ligase complex; IDA:SGD. | | | | | | | | | | GO:0043130; F:ubiquitin binding; IDA:SGD. | | | | | | | | | | GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0000082; P:G1/S transition of mitotic cell cycle; IMP:SGD.::GO:0000086; P:G2/M transition of mitotic cell cycle; IGI:SGD.::GO:0007126; P:meiosis; IMP:SGD.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0042787; P:protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IDA:SGD.::GO:0031146; P:SCF-dependent proteasomal ubiquitin-dependent protein catabolic process; IDA:SGD.::GO:0030435; P:sporulation resulting in formation of a cellular spore; IEA:UniProtKB-KW. | 3 | O14170 | 703 | POP2_SCHPO WD repeat-containing protein pop2 ... | 159 | 0.01 | 39.7 | 22 | 45 | GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.::GO:0005635; C:nuclear envelope; IDA:PomBase.::GO:0019005; C:SCF ubiquitin ligase complex; IDA:PomBase. | | | | | | | | | | GO:0030674; F:protein binding, bridging; IPI:PomBase. | | | | | | | | | | GO:0032876; P:negative regulation of DNA endoreduplication; IMP:PomBase.::GO:0007346; P:regulation of mitotic cell cycle; IC:PomBase.::GO:0006511; P:ubiquitin-dependent protein catabolic process; TAS:PomBase. | 4 | P87060 | 775 | POP1_SCHPO WD repeat-containing protein pop1 ... | 82 | 2.6 | 32.3 | 27 | 43 | GO:0005634; C:nucleus; IDA:PomBase.::GO:0019005; C:SCF ubiquitin ligase complex; IDA:PomBase. | | | | | | | | | | GO:0030674; F:protein binding, bridging; IPI:PomBase. | | | | | | | | | | GO:0006995; P:cellular response to nitrogen starvation; IGI:PomBase.::GO:0000747; P:conjugation with cellular fusion; IMP:PomBase.::GO:0008054; P:cyclin catabolic process; IMP:PomBase.::GO:0007346; P:regulation of mitotic cell cycle; IC:PomBase. | 5 | P53699 | 684 | CDC4_CANAX Cell division control protein 4 OS... | 103 | 2.8 | 32.3 | 24 | 40 | | | | | | | | | | | | | | | | | | | | | GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0030435; P:sporulation resulting in formation of a cellular spore; IEA:UniProtKB-KW. | 6 | Q969H0 | 707 | FBXW7_HUMAN F-box/WD repeat-containing protei... | 145 | 0.000008 | 48.9 | 26 | 46 | GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.::GO:0005654; C:nucleoplasm; TAS:Reactome.::GO:0043234; C:protein complex; IDA:UniProtKB.::GO:0019005; C:SCF ubiquitin ligase complex; IDA:UniProtKB. | | | | | | | | | | GO:0005515; F:protein binding; IPI:UniProtKB. | | | | | | | | | | GO:0034644; P:cellular response to UV; IDA:UniProtKB.::GO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW.::GO:0055088; P:lipid homeostasis; ISS:BHF-UCL.::GO:0032876; P:negative regulation of DNA endoreduplication; IMP:BHF-UCL.::GO:2000346; P:negative regulation of hepatocyte proliferation; ISS:BHF-UCL.::GO:0045746; P:negative regulation of Notch signaling pathway; ISS:BHF-UCL.::GO:2000639; P:negative regulation of SREBP-mediated signaling pathway; ISS:BHF-UCL.::GO:0010868; P:negative regulation of triglyceride biosynthetic process; ISS:BHF-UCL.::GO:0007219; P:Notch signaling pathway; TAS:Reactome.::GO:0045741; P:positive regulation of epidermal growth factor-activated receptor activity; IDA:BHF-UCL.::GO:0070374; P:positive regulation of ERK1 and ERK2 cascade; IMP:BHF-UCL.::GO:2000060; P:positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process; IDA:BHF-UCL.::GO:0050821; P:protein stabilization; IDA:BHF-UCL.::GO:0016567; P:protein ubiquitination; IDA:UniProtKB.::GO:0010883; P:regulation of lipid storage; ISS:BHF-UCL.::GO:0032880; P:regulation of protein localization; ISS:BHF-UCL.::GO:0006974; P:response to DNA damage stimulus; IDA:UniProtKB.::GO:0031146; P:SCF-dependent proteasomal ubiquitin-dependent protein catabolic process; IDA:UniProtKB.::GO:0007062; P:sister chromatid cohesion; IMP:BHF-UCL.::GO:0001944; P:vasculature development; TAS:BHF-UCL. | 7 | Q8VBV4 | 629 | FBXW7_MOUSE F-box/WD repeat-containing protei... | 145 | 0.000008 | 48.5 | 26 | 46 | GO:0005783; C:endoplasmic reticulum; IDA:MGI.::GO:0005794; C:Golgi apparatus; IDA:MGI.::GO:0005634; C:nucleus; IDA:BHF-UCL.::GO:0048471; C:perinuclear region of cytoplasm; IDA:BHF-UCL.::GO:0019005; C:SCF ubiquitin ligase complex; ISS:UniProtKB. | | | | | | | | | | GO:0005515; F:protein binding; IPI:MGI.::GO:0003700; F:sequence-specific DNA binding transcription factor activity; IDA:MGI. | | | | | | | | | | GO:0007219; P:Notch signaling pathway; IDA:MGI.::GO:0016567; P:protein ubiquitination; ISS:UniProtKB.::GO:0031146; P:SCF-dependent proteasomal ubiquitin-dependent protein catabolic process; ISS:UniProtKB. | 8 | Q61FW2 | 589 | SEL10_CAEBR F-box/WD repeat-containing protei... | 153 | 0.005 | 40.4 | 24 | 44 | | | | | | | | | | | | | | | | | | | | | | 9 | Q93794 | 587 | SEL10_CAEEL F-box/WD repeat-containing protei... | 158 | 0.0004 | 43.9 | 22 | 46 | GO:0030424; C:axon; IDA:UniProtKB.::GO:0005737; C:cytoplasm; IDA:WormBase. | | | | | | | | | | GO:0005515; F:protein binding; IPI:UniProtKB. | | | | | | | | | | GO:0046660; P:female sex differentiation; IMP:UniProtKB.::GO:0045746; P:negative regulation of Notch signaling pathway; IGI:UniProtKB. | 10 | Q8YTC2 | 1258 | Y2800_NOSS1 Uncharacterized WD repeat-contain... | 201 | 0.001 | 42.7 | 24 | 43 | | | | | | | | | | | GO:0043531; F:ADP binding; IEA:InterPro. | | | | | | | | | | GO:0006952; P:defense response; IEA:InterPro. | 11 | Q09990 | 665 | LIN23_CAEEL F-box/WD repeat-containing protei... | 161 | 0.2 | 35.8 | 24 | 45 | GO:0005737; C:cytoplasm; NAS:UniProtKB.::GO:0005634; C:nucleus; IDA:WormBase. | | | | | | | | | | GO:0046983; F:protein dimerization activity; IEA:InterPro. | | | | | | | | | | GO:0010171; P:body morphogenesis; IMP:WormBase.::GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0008340; P:determination of adult lifespan; IMP:WormBase.::GO:0009792; P:embryo development ending in birth or egg hatching; IMP:WormBase.::GO:0040007; P:growth; IMP:WormBase.::GO:0040035; P:hermaphrodite genitalia development; IMP:WormBase.::GO:0040011; P:locomotion; IMP:WormBase.::GO:0008285; P:negative regulation of cell proliferation; IMP:UniProtKB.::GO:0040015; P:negative regulation of multicellular organism growth; IMP:WormBase.::GO:0002119; P:nematode larval development; IMP:WormBase.::GO:0048812; P:neuron projection morphogenesis; IMP:WormBase.::GO:0040010; P:positive regulation of growth rate; IMP:WormBase.::GO:0006898; P:receptor-mediated endocytosis; IMP:WormBase. | 12 | O61585 | 690 | KTNB1_STRPU Katanin p80 WD40-containing subun... | 186 | 0.0000000002 | 62.8 | 30 | 47 | GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell.::GO:0000922; C:spindle pole; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW. | 13 | Q9Y297 | 605 | FBW1A_HUMAN F-box/WD repeat-containing protei... | 112 | 0.28 | 35 | 27 | 47 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0019005; C:SCF ubiquitin ligase complex; IDA:UniProtKB. | | | | | | | | | | GO:0046983; F:protein dimerization activity; IEA:InterPro. | | | | | | | | | | GO:0031145; P:anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process; TAS:Reactome.::GO:0044419; P:interspecies interaction between organisms; IEA:UniProtKB-KW.::GO:0043433; P:negative regulation of sequence-specific DNA binding transcription factor activity; TAS:BHF-UCL.::GO:0045879; P:negative regulation of smoothened signaling pathway; TAS:BHF-UCL.::GO:0045892; P:negative regulation of transcription, DNA-dependent; IMP:UniProtKB.::GO:0045862; P:positive regulation of proteolysis; IMP:UniProtKB.::GO:0051437; P:positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle; TAS:Reactome.::GO:0031648; P:protein destabilization; IMP:UniProtKB.::GO:0016032; P:viral reproduction; TAS:Reactome.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW. | 14 | Q3ULA2 | 605 | FBW1A_MOUSE F-box/WD repeat-containing protei... | 88 | 0.52 | 34.3 | 27 | 42 | GO:0005829; C:cytosol; TAS:Reactome.::GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0019005; C:SCF ubiquitin ligase complex; ISS:UniProtKB. | | | | | | | | | | GO:0008013; F:beta-catenin binding; IDA:BHF-UCL.::GO:0046983; F:protein dimerization activity; IEA:InterPro.::GO:0045309; F:protein phosphorylated amino acid binding; IDA:BHF-UCL.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:BHF-UCL. | | | | | | | | | | GO:0060444; P:branching involved in mammary gland duct morphogenesis; IMP:MGI.::GO:0071407; P:cellular response to organic cyclic compound; IDA:MGI.::GO:0033598; P:mammary gland epithelial cell proliferation; IMP:MGI.::GO:0045892; P:negative regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0042753; P:positive regulation of circadian rhythm; IMP:UniProtKB.::GO:0045862; P:positive regulation of proteolysis; ISS:UniProtKB.::GO:0045893; P:positive regulation of transcription, DNA-dependent; IMP:UniProtKB.::GO:0006470; P:protein dephosphorylation; IDA:UniProtKB.::GO:0031648; P:protein destabilization; ISS:UniProtKB.::GO:0000209; P:protein polyubiquitination; IDA:BHF-UCL.::GO:0051726; P:regulation of cell cycle; IMP:MGI.::GO:0043122; P:regulation of I-kappaB kinase/NF-kappaB cascade; IMP:MGI.::GO:0061136; P:regulation of proteasomal protein catabolic process; IDA:MGI.::GO:0006511; P:ubiquitin-dependent protein catabolic process; ISS:UniProtKB.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW. | 15 | Q4V8C4 | 328 | WDR5B_RAT WD repeat-containing protein 5B OS=... | 168 | 0.000000001 | 59.3 | 29 | 44 | | | | | | | | | | | | | | | | | | | | | | 16 | P90648 | 732 | MHCKB_DICDI Myosin heavy chain kinase B OS=Di... | 104 | 0.011 | 39.3 | 34 | 44 | GO:0005826; C:actomyosin contractile ring; IDA:dictyBase. | | | | | | | | | | GO:0005524; F:ATP binding; IC:dictyBase.::GO:0016905; F:myosin heavy chain kinase activity; IDA:dictyBase.::GO:0045159; F:myosin II binding; IPI:dictyBase. | | | | | | | | | | GO:0000910; P:cytokinesis; IMP:dictyBase.::GO:0031037; P:myosin II filament disassembly; IMP:dictyBase.::GO:0018107; P:peptidyl-threonine phosphorylation; IDA:dictyBase.::GO:0046777; P:protein autophosphorylation; IDA:dictyBase. | 17 | Q9UKB1 | 542 | FBW1B_HUMAN F-box/WD repeat-containing protei... | 167 | 0.038 | 37.7 | 25 | 44 | GO:0005813; C:centrosome; IDA:UniProtKB.::GO:0005829; C:cytosol; ISS:UniProtKB.::GO:0005634; C:nucleus; ISS:UniProtKB.::GO:0019005; C:SCF ubiquitin ligase complex; IDA:UniProtKB. | | | | | | | | | | GO:0046983; F:protein dimerization activity; IEA:InterPro.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB. | | | | | | | | | | GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0045892; P:negative regulation of transcription, DNA-dependent; IMP:UniProtKB.::GO:0042753; P:positive regulation of circadian rhythm; ISS:UniProtKB.::GO:0045862; P:positive regulation of proteolysis; IMP:UniProtKB.::GO:0045893; P:positive regulation of transcription, DNA-dependent; ISS:UniProtKB.::GO:0006470; P:protein dephosphorylation; ISS:UniProtKB.::GO:0031648; P:protein destabilization; IMP:UniProtKB.::GO:0000209; P:protein polyubiquitination; IDA:UniProtKB.::GO:0048511; P:rhythmic process; IEA:UniProtKB-KW.::GO:0031146; P:SCF-dependent proteasomal ubiquitin-dependent protein catabolic process; IDA:UniProtKB.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW. | 18 | Q5SRY7 | 542 | FBW1B_MOUSE F-box/WD repeat-containing protei... | 167 | 0.066 | 37 | 25 | 44 | GO:0005829; C:cytosol; IDA:UniProtKB.::GO:0005634; C:nucleus; IDA:UniProtKB.::GO:0019005; C:SCF ubiquitin ligase complex; IDA:UniProtKB. | | | | | | | | | | GO:0046983; F:protein dimerization activity; IEA:InterPro.::GO:0004842; F:ubiquitin-protein ligase activity; IDA:UniProtKB. | | | | | | | | | | GO:0007049; P:cell cycle; IEA:UniProtKB-KW.::GO:0042347; P:negative regulation of NF-kappaB import into nucleus; IMP:UniProtKB.::GO:0042753; P:positive regulation of circadian rhythm; IMP:UniProtKB.::GO:0045862; P:positive regulation of proteolysis; ISS:UniProtKB.::GO:0045893; P:positive regulation of transcription, DNA-dependent; IMP:UniProtKB.::GO:0006470; P:protein dephosphorylation; IDA:UniProtKB.::GO:0031648; P:protein destabilization; ISS:UniProtKB.::GO:0000209; P:protein polyubiquitination; IDA:UniProtKB.::GO:0048511; P:rhythmic process; IEA:UniProtKB-KW.::GO:0031146; P:SCF-dependent proteasomal ubiquitin-dependent protein catabolic process; IMP:UniProtKB.::GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW. | 19 | Q7S8R5 | 645 | MDV1_NEUCR Mitochondrial division protein 1 O... | 78 | 1 | 33.5 | 28 | 51 | GO:0005741; C:mitochondrial outer membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | | 20 | P53622 | 1201 | COPA_YEAST Coatomer subunit alpha OS=Saccharo... | 33 | 0.99 | 33.5 | 39 | 61 | GO:0030126; C:COPI vesicle coat; IMP:SGD. | | | | | | | | | | GO:0005198; F:structural molecule activity; IEA:InterPro.::GO:0043130; F:ubiquitin binding; IDA:SGD. | | | | | | | | | | GO:0006888; P:ER to Golgi vesicle-mediated transport; IMP:SGD.::GO:0006886; P:intracellular protein transport; IEA:InterPro.::GO:0006890; P:retrograde vesicle-mediated transport, Golgi to ER; IMP:SGD. | 21 | Q91854 | 518 | TRCB_XENLA Beta-TrCP OS=Xenopus laevis (Afric... | 112 | 0.22 | 35.4 | 27 | 46 | | | | | | | | | | | GO:0046983; F:protein dimerization activity; IEA:InterPro. | | | | | | | | | | GO:0016055; P:Wnt receptor signaling pathway; IEA:UniProtKB-KW. | 22 | Q9D7H2 | 328 | WDR5B_MOUSE WD repeat-containing protein 5B O... | 101 | 0.002 | 41.6 | 26 | 44 | | | | | | | | | | | | | | | | | | | | | | 23 | Q2H139 | 657 | MDV1_CHAGB Mitochondrial division protein 1 O... | 152 | 0.0004 | 43.9 | 29 | 43 | GO:0005741; C:mitochondrial outer membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | | 24 | Q758R7 | 715 | MDV1_ASHGO Mitochondrial division protein 1 O... | 204 | 0.69 | 33.9 | 24 | 37 | GO:0005741; C:mitochondrial outer membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | | 25 | Q9VZF4 | 1326 | FBXW7_DROME F-box/WD repeat-containing protei... | 140 | 0.00006 | 46.2 | 26 | 44 | GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.::GO:0019005; C:SCF ubiquitin ligase complex; NAS:FlyBase. | | | | | | | | | | GO:0030332; F:cyclin binding; TAS:FlyBase. | | | | | | | | | | GO:0007411; P:axon guidance; IMP:FlyBase.::GO:0008054; P:cyclin catabolic process; TAS:FlyBase.::GO:0042023; P:DNA endoreduplication; IMP:FlyBase.::GO:0060253; P:negative regulation of glial cell proliferation; IGI:FlyBase.::GO:0045926; P:negative regulation of growth; IMP:FlyBase.::GO:0007096; P:regulation of exit from mitosis; TAS:FlyBase.::GO:0007088; P:regulation of mitosis; IMP:FlyBase.::GO:0030162; P:regulation of proteolysis; TAS:FlyBase. | 26 | Q6CB13 | 565 | MDV1_YARLI Mitochondrial division protein 1 O... | 185 | 0.42 | 34.7 | 26 | 36 | GO:0005741; C:mitochondrial outer membrane; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | | 27 | A0CH87 | 403 | LIS12_PARTE Lissencephaly-1 homolog 2 OS=Para... | 115 | 0.032 | 38.1 | 30 | 50 | GO:0005874; C:microtubule; IEA:UniProtKB-KW.::GO:0005815; C:microtubule organizing center; IEA:UniProtKB-SubCell. | | | | | | | | | | | | | | | | | | | | GO:0051301; P:cell division; IEA:UniProtKB-KW.::GO:0007067; P:mitosis; IEA:UniProtKB-KW.::GO:0006810; P:transport; IEA:UniProtKB-KW. | 28 | Q8CIE6 | 1224 | COPA_MOUSE Coatomer subunit alpha OS=Mus musc... | 143 | 0.037 | 38.1 | 22 | 38 | GO:0030126; C:COPI vesicle coat; IEA:InterPro.::GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005179; F:hormone activity; IEA:UniProtKB-KW.::GO:0005198; F:structural molecule activity; IEA:InterPro. | | | | | | | | | | GO:0006886; P:intracellular protein transport; IEA:InterPro.::GO:0016192; P:vesicle-mediated transport; IEA:UniProtKB-KW. | 29 | Q27954 | 1224 | COPA_BOVIN Coatomer subunit alpha OS=Bos taur... | 143 | 0.037 | 38.1 | 22 | 38 | GO:0030126; C:COPI vesicle coat; IDA:UniProtKB.::GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell. | | | | | | | | | | GO:0005179; F:hormone activity; IEA:UniProtKB-KW.::GO:0005198; F:structural molecule activity; IEA:InterPro. | | | | | | | | | | GO:0006891; P:intra-Golgi vesicle-mediated transport; TAS:UniProtKB.::GO:0006886; P:intracellular protein transport; IEA:InterPro.::GO:0006890; P:retrograde vesicle-mediated transport, Golgi to ER; TAS:UniProtKB. | 30 | Q8YRI1 | 1526 | YY46_NOSS1 Uncharacterized WD repeat-containi... | 145 | 0.005 | 40.4 | 25 | 44 | | | | | | | | | | | | | | | | | | | | | | 31 | Q9P7I3 | 651 | MDV1_SCHPO Mitochondrial division protein 1 O... | 121 | 0.59 | 34.3 | 28 | 45 | GO:0030015; C:CCR4-NOT core complex; NAS:PomBase.::GO:0005741; C:mitochondrial outer membrane; ISS:PomBase. | | | | | | | | | | GO:0051020; F:GTPase binding; NAS:PomBase. | | | | | | | | | | GO:0000266; P:mitochondrial fission; ISS:PomBase.::GO:0000002; P:mitochondrial genome maintenance; ISS:PomBase.::GO:0006355; P:regulation of transcription, DNA-dependent; ISS:PomBase.::GO:0006354; P:transcription elongation, DNA-dependent; IC:PomBase. |
