Fungal Genome Collection
University of Nebraska Lincoln
School of Biological Sciences and Center for Plant Science Innovation
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UniProt_SwissProt BLAST: Single locus
Species:
Saccharomyces cerevisiae S288C
Locus:
YER065C
Length:
557
Number of sequences:
5887
Description:
YER065C ICL1 SGDID:S000000867, Chr V from 286914-285241, Genome Release 64-1-1, reverse complement, Verified ORF, "Isocitrate lyase, catalyzes the formation of succinate and glyoxylate from isocitrate, a key reaction of the glyoxylate cycle; expression of ICL1 is induced by growth on ethanol and repressed by growth on glucose"
rec.SubjectHit LengthDescriptionAlign.LenE valueBit score% ident.  % pos.GO associations
31P49296    576   ACEA_CUCSA Isocitrate lyase OS=Cucumis sativu...5470     564     50     69GO:0009514; C:glyoxysome; IEA:UniProtKB-SubCell.
GO:0004451; F:isocitrate lyase activity; IEA:EC.
GO:0006097; P:glyoxylate cycle; IEA:UniProtKB-KW.::GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW.
32Q12031    575   ACEB_YEAST Mitochondrial 2-methylisocitrate l...5433e-146     440     42     60GO:0005759; C:mitochondrial matrix; IDA:SGD.
GO:0004451; F:isocitrate lyase activity; IEA:InterPro.::GO:0046421; F:methylisocitrate lyase activity; IDA:SGD.
GO:0019541; P:propionate metabolic process; IDA:SGD.::GO:0006567; P:threonine catabolic process; IEP:SGD.
33Q9P6J1    518   ACEB_SCHPO Mitochondrial 2-methylisocitrate l...5084e-93     301     35     54GO:0005829; C:cytosol; IDA:PomBase.::GO:0005759; C:mitochondrial matrix; ISS:PomBase.
GO:0004451; F:isocitrate lyase activity; IEA:InterPro.::GO:0046421; F:methylisocitrate lyase activity; ISS:PomBase.
GO:0019541; P:propionate metabolic process; ISS:PomBase.::GO:0006567; P:threonine catabolic process; ISS:PomBase.
34P46831    606   ACEA_MYCLE Isocitrate lyase OS=Mycobacterium ...5467e-85     281     33     48GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004451; F:isocitrate lyase activity; IEA:EC.
GO:0006097; P:glyoxylate cycle; IEA:UniProtKB-KW.::GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW.
35Q9K9H0    427   ACEA_BACHD Isocitrate lyase OS=9153 / C-125)....1792e-31     129     40     58GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004451; F:isocitrate lyase activity; IEA:EC.
GO:0006097; P:glyoxylate cycle; IEA:UniProtKB-KW.::GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW.
36P0A9G6    434   ACEA_ECOLI Isocitrate lyase OS=Escherichia co...1786e-37     146     41     59GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004451; F:isocitrate lyase activity; IEA:EC.
GO:0006097; P:glyoxylate cycle; IEA:UniProtKB-KW.::GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW.
37P0A9G7    434   ACEA_ECOL6 Isocitrate lyase OS=Escherichia co...1786e-37     146     41     59GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004451; F:isocitrate lyase activity; IEA:EC.
GO:0006097; P:glyoxylate cycle; IEA:UniProtKB-KW.::GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW.
38P51066    434   ACEA_SALTY Isocitrate lyase OS=Salmonella typ...1783e-37     147     42     59GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004451; F:isocitrate lyase activity; IEA:EC.
GO:0006097; P:glyoxylate cycle; IEA:UniProtKB-KW.::GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW.
39P41554    429   ACEA_RHOFA Isocitrate lyase OS=Rhodococcus fa...1781e-34     139     40     59GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004451; F:isocitrate lyase activity; IEA:EC.
GO:0006097; P:glyoxylate cycle; IEA:UniProtKB-KW.::GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW.
40P0A5H3    428   ACEA_MYCTU Isocitrate lyase OS=Mycobacterium ...1773e-35     140     41     59GO:0005829; C:cytosol; IDA:MTBBASE.::GO:0005886; C:plasma membrane; IDA:MTBBASE.
GO:0004451; F:isocitrate lyase activity; IDA:MTBBASE.::GO:0046421; F:methylisocitrate lyase activity; IDA:MTBBASE.
GO:0071456; P:cellular response to hypoxia; IEP:MTBBASE.::GO:0006097; P:glyoxylate cycle; IDA:MTBBASE.::GO:0006102; P:isocitrate metabolic process; IDA:MTBBASE.::GO:0075141; P:maintenance of symbiont tolerance to host environment; IMP:MTBBASE.::GO:0009405; P:pathogenesis; IMP:MTBBASE.::GO:0010034; P:response to acetate; IDA:MTBBASE.::GO:0001101; P:response to acid; IEP:MTBBASE.::GO:0070542; P:response to fatty acid; IDA:MTBBASE.::GO:0052572; P:response to host immune response; IEP:MTBBASE.::GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW.
41P0A5H4    428   ACEA_MYCBO Isocitrate lyase OS=Mycobacterium ...1773e-35     140     41     59GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004451; F:isocitrate lyase activity; IEA:EC.
GO:0006097; P:glyoxylate cycle; IEA:UniProtKB-KW.::GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW.
42P42449    432   ACEA_CORGL Isocitrate lyase OS=LMG 3730 / NCI...1788e-37     145     41     60GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004451; F:isocitrate lyase activity; IEA:EC.
GO:0006097; P:glyoxylate cycle; IEA:UniProtKB-KW.::GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW.
43Q8RQN6    431   ACEA_COREF Isocitrate lyase OS=11189 / NBRC 1...1786e-37     145     42     60GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004451; F:isocitrate lyase activity; IEA:EC.
GO:0006097; P:glyoxylate cycle; IEA:UniProtKB-KW.::GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW.
44Q10663    968   GCP_CAEEL Bifunctional glyoxylate cycle prote...2557e-38     153     38     56
GO:0004451; F:isocitrate lyase activity; IEA:EC.::GO:0004474; F:malate synthase activity; IEA:EC.
GO:0008340; P:determination of adult lifespan; IMP:WormBase.::GO:0009790; P:embryo development; IPI:WormBase.::GO:0006097; P:glyoxylate cycle; IEA:UniProtKB-KW.::GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW.
45Q9I0K4    531   ACEA_PSEAE Isocitrate lyase OS=12228). GN=PA2...6022e-36     145     26     41GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004451; F:isocitrate lyase activity; IEA:EC.
GO:0006097; P:glyoxylate cycle; IEA:UniProtKB-KW.::GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW.
46O50078    540   ACEA_HYPME Isocitrate lyase OS=Hyphomicrobium...2180.00000001     61.2     25     38GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
GO:0004451; F:isocitrate lyase activity; IDA:UniProtKB.::GO:0000287; F:magnesium ion binding; IDA:UniProtKB.::GO:0046914; F:transition metal ion binding; IDA:UniProtKB.
GO:0006097; P:glyoxylate cycle; IDA:UniProtKB.::GO:0006099; P:tricarboxylic acid cycle; IDA:UniProtKB.
47P20699    58   ACEA_HELAN Isocitrate lyase OS=Helianthus ann...560.0000000000001     71.2     57     73GO:0009514; C:glyoxysome; IEA:UniProtKB-SubCell.
GO:0004451; F:isocitrate lyase activity; IEA:EC.
GO:0006097; P:glyoxylate cycle; IEA:UniProtKB-KW.::GO:0006099; P:tricarboxylic acid cycle; IEA:UniProtKB-KW.
48O49290    339   CPPM_ARATH Carboxyvinyl-carboxyphosphonate ph...870.00000000002     68.9     45     59GO:0009570; C:chloroplast stroma; IDA:TAIR.
GO:0008807; F:carboxyvinyl-carboxyphosphonate phosphorylmutase activity; IEA:EC.
49P54528    301   PRPB_BACSU Methylisocitrate lyase OS=Bacillus...1040.00000000007     67     34     53
GO:0046421; F:methylisocitrate lyase activity; IEA:EC.
GO:0019629; P:propionate catabolic process, 2-methylcitrate cycle; IEA:InterPro.
50P11435    295   CPPM_STRHY Carboxyvinyl-carboxyphosphonate ph...1170.000000004     61.6     30     50
GO:0008807; F:carboxyvinyl-carboxyphosphonate phosphorylmutase activity; IEA:EC.
GO:0017000; P:antibiotic biosynthetic process; IEA:UniProtKB-KW.
51P77541    296   PRPB_ECOLI Methylisocitrate lyase OS=Escheric...1060.00000002     59.7     35     53
GO:0046421; F:methylisocitrate lyase activity; IEA:EC.
GO:0019629; P:propionate catabolic process, 2-methylcitrate cycle; IEA:InterPro.
52Q9Z9T7    300   PRPB_BACHD Methylisocitrate lyase OS=9153 / C...1040.00000002     59.7     31     53
GO:0046421; F:methylisocitrate lyase activity; IEA:EC.
GO:0019629; P:propionate catabolic process, 2-methylcitrate cycle; IEA:InterPro.
53Q0QLE4    289   DML_EUBBA 2,3-dimethylmalate lyase OS=Eubacte...1050.00000004     58.5     33     52
GO:0047529; F:2,3-dimethylmalate lyase activity; IDA:UniProtKB.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
GO:0051187; P:cofactor catabolic process; IDA:UniProtKB.
54Q9KSC2    308   PRPB_VIBCH Methylisocitrate lyase OS=Vibrio c...950.00000005     58.5     33     57
GO:0046421; F:methylisocitrate lyase activity; IEA:EC.
GO:0019629; P:propionate catabolic process, 2-methylcitrate cycle; IEA:InterPro.
55Q9YFM7    308   PRPB_AERPE Methylisocitrate lyase OS=100138 /...1210.0000003     56.2     30     46
GO:0046421; F:methylisocitrate lyase activity; IEA:EC.
GO:0019629; P:propionate catabolic process, 2-methylcitrate cycle; IEA:InterPro.
56Q05957    318   PDP_DIACA Petal death protein OS=Dianthus car...1000.0000003     56.2     36     50
GO:0047776; F:citramalate lyase activity; IEA:EC.::GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.::GO:0030603; F:oxaloacetase activity; IEA:EC.::GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
57Q56062    295   PRPB_SALTY Methylisocitrate lyase OS=Salmonel...1060.000001     54.3     32     51
GO:0046421; F:methylisocitrate lyase activity; IEA:EC.
GO:0019629; P:propionate catabolic process, 2-methylcitrate cycle; IEA:InterPro.
58Q8NSL2    307   PRPB2_CORGL Probable methylisocitrate lyase 2...1040.00002     50.1     30     46
GO:0046421; F:methylisocitrate lyase activity; IEA:EC.
GO:0019629; P:propionate catabolic process, 2-methylcitrate cycle; IEA:InterPro.
59Q8NSH8    305   PRPB1_CORGL Probable methylisocitrate lyase 1...1030.0003     46.6     28     47
GO:0046421; F:methylisocitrate lyase activity; IEA:EC.
GO:0019629; P:propionate catabolic process, 2-methylcitrate cycle; IEA:InterPro.
60P33182    300   PEPM_TETPY Phosphoenolpyruvate phosphomutase ...850.028     40.4     31     48
GO:0050188; F:phosphoenolpyruvate mutase activity; IEA:EC.
61P29247    313   PEPM_STRHY Phosphoenolpyruvate phosphomutase ...850.073     39.3     29     42
GO:0050188; F:phosphoenolpyruvate mutase activity; IEA:EC.
GO:0017000; P:antibiotic biosynthetic process; IEA:UniProtKB-KW.
records
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