UniProt_SwissProt BLAST: Single locus

Species:

Saccharomyces cerevisiae S288C

Locus:

YER061C

Length:

442

Number of sequences:

5887

Description:

YER061C CEM1 SGDID:S000000863, Chr V from 279626-278298, Genome Release 64-1-1, reverse complement, Verified ORF, "Mitochondrial beta-keto-acyl synthase with possible role in fatty acid synthesis; required for mitochondrial respiration"

rec.	Subject	Hit Length	Description	Align.Len	E value	Bit score	% ident.	% pos.	GO associations
61	P16539	409	KAS2_STRGA Tetracenomycin C polyketide putati...	453	6e-26	112	27	43
									GO:0016746; F:transferase activity, transferring acyl groups; IEA:UniProtKB-KW.
									GO:0017000; P:antibiotic biosynthetic process; IEA:UniProtKB-KW.
62	P96202	2188	PPSC_MYCTU Phthiocerol synthesis polyketide s...	450	8e-26	114	25	42	GO:0005829; C:cytosol; IDA:MTBBASE.::GO:0005886; C:plasma membrane; IDA:MTBBASE.::GO:0034081; C:polyketide synthase complex; ISS:UniProtKB.
									GO:0004315; F:3-oxoacyl-[acyl-carrier-protein synthase activity; IEA:EC.::GO:0000036; F:acyl carrier activity; IEA:InterPro.::GO:0048037; F:cofactor binding; IEA:InterPro.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.::GO:0031177; F:phosphopantetheine binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0071770; P:DIM/DIP cell wall layer assembly; IDA:MTBBASE.::GO:0006633; P:fatty acid biosynthetic process; IDA:MTBBASE.::GO:0097041; P:phenolic phthiocerol biosynthetic process; ISS:UniProtKB.::GO:0097040; P:phthiocerol biosynthetic process; ISS:UniProtKB.]
63	Q7TXL8	2188	PPSC_MYCBO Phthiocerol/phenolphthiocerol synt...	450	8e-26	114	25	42	GO:0034081; C:polyketide synthase complex; IMP:UniProtKB.
									GO:0004315; F:3-oxoacyl-[acyl-carrier-protein synthase activity; IEA:EC.::GO:0000036; F:acyl carrier activity; IEA:InterPro.::GO:0048037; F:cofactor binding; IEA:InterPro.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.::GO:0031177; F:phosphopantetheine binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0071766; P:Actinobacterium-type cell wall biogenesis; IMP:UniProtKB.::GO:0006631; P:fatty acid metabolic process; IEA:UniProtKB-KW.::GO:0097041; P:phenolic phthiocerol biosynthetic process; IMP:UniProtKB.::GO:0097040; P:phthiocerol biosynthetic process; IMP:UniProtKB.]
64	Q07017	3519	OL56_STRAT Oleandomycin polyketide synthase, ...	236	5e-24	109	28	47
									GO:0000036; F:acyl carrier activity; IEA:InterPro.::GO:0048037; F:cofactor binding; IEA:InterPro.::GO:0016788; F:hydrolase activity, acting on ester bonds; IEA:InterPro.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:InterPro.::GO:0031177; F:phosphopantetheine binding; IEA:InterPro.::GO:0016746; F:transferase activity, transferring acyl groups; IEA:UniProtKB-KW.
									GO:0017000; P:antibiotic biosynthetic process; IEA:UniProtKB-KW.
65	P96203	1827	PPSD_MYCTU Phthiocerol synthesis polyketide s...	397	1e-25	114	27	45	GO:0005886; C:plasma membrane; IDA:MTBBASE.::GO:0034081; C:polyketide synthase complex; ISS:UniProtKB.
									GO:0004315; F:3-oxoacyl-[acyl-carrier-protein synthase activity; IEA:EC.::GO:0000036; F:acyl carrier activity; IEA:InterPro.::GO:0048037; F:cofactor binding; IEA:InterPro.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.::GO:0031177; F:phosphopantetheine binding; IEA:InterPro.
									GO:0071770; P:DIM/DIP cell wall layer assembly; IDA:MTBBASE.::GO:0006633; P:fatty acid biosynthetic process; IDA:MTBBASE.::GO:0097041; P:phenolic phthiocerol biosynthetic process; ISS:UniProtKB.::GO:0097040; P:phthiocerol biosynthetic process; ISS:UniProtKB.]
66	Q7TXL7	1827	PPSD_MYCBO Phthiocerol/phenolphthiocerol synt...	397	2e-25	114	27	45	GO:0034081; C:polyketide synthase complex; ISS:UniProtKB.
									GO:0004315; F:3-oxoacyl-[acyl-carrier-protein synthase activity; IEA:EC.::GO:0000036; F:acyl carrier activity; IEA:InterPro.::GO:0048037; F:cofactor binding; IEA:InterPro.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.::GO:0031177; F:phosphopantetheine binding; IEA:InterPro.
									GO:0071766; P:Actinobacterium-type cell wall biogenesis; ISS:UniProtKB.::GO:0006631; P:fatty acid metabolic process; IEA:UniProtKB-KW.::GO:0097041; P:phenolic phthiocerol biosynthetic process; ISS:UniProtKB.::GO:0097040; P:phthiocerol biosynthetic process; ISS:UniProtKB.]
67	B0G138	2779	PKS21_DICDI Probable polyketide synthase 21 O...	361	9e-25	111	28	45
									GO:0000036; F:acyl carrier activity; IEA:InterPro.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:InterPro.::GO:0016747; F:transferase activity, transferring acyl groups other than amino-acyl groups; IEA:InterPro.
									GO:0009058; P:biosynthetic process; IEA:InterPro.
68	Q54T36	2778	PKS19_DICDI Probable polyketide synthase 19 O...	361	9e-25	111	28	45
									GO:0000036; F:acyl carrier activity; IEA:InterPro.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:InterPro.::GO:0016747; F:transferase activity, transferring acyl groups other than amino-acyl groups; IEA:InterPro.
									GO:0009058; P:biosynthetic process; IEA:InterPro.
69	Q55E72	3147	PKS1_DICDI Probable polyketide synthase 1 OS=...	483	9e-24	108	26	41	GO:0005622; C:intracellular; IC:dictyBase.
									GO:0000036; F:acyl carrier activity; IEA:InterPro.::GO:0048037; F:cofactor binding; IEA:InterPro.::GO:0016210; F:naringenin-chalcone synthase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:InterPro.
									GO:0009813; P:flavonoid biosynthetic process; IEA:UniProtKB-KW.::GO:0030639; P:polyketide biosynthetic process; IDA:dictyBase.::GO:0019505; P:resorcinol metabolic process; IDA:dictyBase.
70	P22367	1774	MSAS_PENPA 6-methylsalicylic acid synthase OS...	442	4e-23	106	25	44
									GO:0050641; F:6-methylsalicylic acid synthase activity; IEA:EC.::GO:0000036; F:acyl carrier activity; IEA:InterPro.::GO:0048037; F:cofactor binding; IEA:InterPro.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0031177; F:phosphopantetheine binding; IEA:InterPro.
									GO:0017000; P:antibiotic biosynthetic process; IEA:UniProtKB-KW.
71	Q869W9	2603	PKS16_DICDI Probable polyketide synthase 16 O...	356	1e-22	104	26	41
									GO:0000036; F:acyl carrier activity; IEA:InterPro.::GO:0048037; F:cofactor binding; IEA:InterPro.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:InterPro.::GO:0016747; F:transferase activity, transferring acyl groups other than amino-acyl groups; IEA:InterPro.
									GO:0009058; P:biosynthetic process; IEA:InterPro.::GO:0019953; P:sexual reproduction; IEP:dictyBase.
72	O31782	5488	PKSN_BACSU Polyketide synthase PksN OS=Bacill...	278	1e-16	86.7	26	45	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0000036; F:acyl carrier activity; IEA:InterPro.::GO:0048037; F:cofactor binding; IEA:InterPro.::GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0031177; F:phosphopantetheine binding; IEA:InterPro.::GO:0016746; F:transferase activity, transferring acyl groups; IEA:UniProtKB-KW.
									GO:0009058; P:biosynthetic process; IEA:InterPro.
73	Q12397	2211	STCA_EMENI Putative sterigmatocystin biosynth...	359	6e-22	102	26	42
									GO:0000036; F:acyl carrier activity; IEA:InterPro.::GO:0048037; F:cofactor binding; IEA:InterPro.::GO:0016788; F:hydrolase activity, acting on ester bonds; IEA:InterPro.::GO:0016746; F:transferase activity, transferring acyl groups; IEA:UniProtKB-KW.
									GO:0009058; P:biosynthetic process; IEA:InterPro.
74	Q869X2	2604	PKS17_DICDI Probable polyketide synthase 17 O...	356	2e-21	100	25	40
									GO:0000036; F:acyl carrier activity; IEA:InterPro.::GO:0048037; F:cofactor binding; IEA:InterPro.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:InterPro.::GO:0016747; F:transferase activity, transferring acyl groups other than amino-acyl groups; IEA:InterPro.
									GO:0009058; P:biosynthetic process; IEA:InterPro.
75	Q12053	2109	PKSL1_ASPPA Aflatoxin biosynthesis polyketide...	355	3e-21	100	26	42
									GO:0000036; F:acyl carrier activity; IEA:InterPro.::GO:0048037; F:cofactor binding; IEA:InterPro.::GO:0016788; F:hydrolase activity, acting on ester bonds; IEA:InterPro.::GO:0016746; F:transferase activity, transferring acyl groups; IEA:UniProtKB-KW.
									GO:0009058; P:biosynthetic process; IEA:InterPro.
76	Q02062	407	KASB_STRCO Actinorhodin polyketide putative b...	444	4e-21	98.2	25	43
									GO:0016746; F:transferase activity, transferring acyl groups; IEA:UniProtKB-KW.
									GO:0017000; P:antibiotic biosynthetic process; IEA:UniProtKB-KW.
77	Q02251	2111	MCAS_MYCBO Mycocerosic acid synthase OS=Mycob...	444	6e-21	99.8	26	42	GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
									GO:0000036; F:acyl carrier activity; IEA:InterPro.::GO:0048037; F:cofactor binding; IEA:InterPro.::GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.::GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0050111; F:mycocerosate synthase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.::GO:0031177; F:phosphopantetheine binding; IEA:InterPro.::GO:0008270; F:zinc ion binding; IEA:InterPro.
									GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.
78	Q03149	2157	WA_EMENI Conidial yellow pigment biosynthesis...	357	2e-20	98.2	26	41
									GO:0000036; F:acyl carrier activity; IEA:InterPro.::GO:0048037; F:cofactor binding; IEA:InterPro.::GO:0016788; F:hydrolase activity, acting on ester bonds; IEA:InterPro.::GO:0031177; F:phosphopantetheine binding; IEA:InterPro.::GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
									GO:0009058; P:biosynthetic process; IEA:InterPro.::GO:0048315; P:conidium formation; IEA:UniProtKB-KW.::GO:0030435; P:sporulation resulting in formation of a cellular spore; IEA:UniProtKB-KW.
79	P40806	5043	PKSJ_BACSU Polyketide synthase PksJ OS=Bacill...	442	0.000000000000001	83.6	25	41	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0000036; F:acyl carrier activity; IEA:InterPro.::GO:0048037; F:cofactor binding; IEA:InterPro.::GO:0016874; F:ligase activity; IEA:UniProtKB-KW.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0031177; F:phosphopantetheine binding; IEA:InterPro.::GO:0016746; F:transferase activity, transferring acyl groups; IEA:UniProtKB-KW.
									GO:0017000; P:antibiotic biosynthetic process; IEA:UniProtKB-KW.
80	O31784	2543	PKSR_BACSU Polyketide synthase PksR OS=Bacill...	457	2e-18	91.7	23	42	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0000036; F:acyl carrier activity; IEA:InterPro.::GO:0048037; F:cofactor binding; IEA:InterPro.::GO:0016788; F:hydrolase activity, acting on ester bonds; IEA:InterPro.::GO:0031177; F:phosphopantetheine binding; IEA:InterPro.::GO:0016747; F:transferase activity, transferring acyl groups other than amino-acyl groups; IEA:InterPro.
									GO:0009058; P:biosynthetic process; IEA:InterPro.
81	Q71SP7	2513	FAS_BOVIN Fatty acid synthase OS=Bos taurus (...	444	7e-20	96.7	25	42	GO:0042470; C:melanosome; IEA:UniProtKB-SubCell.
									GO:0004317; F:3-hydroxypalmitoyl-[acyl-carrier-protein dehydratase activity; IEA:EC.::GO:0004316; F:3-oxoacyl-[acyl-carrier-protein reductase (NADPH) activity; IEA:EC.::GO:0004315; F:3-oxoacyl-[acyl-carrier-protein synthase activity; IEA:EC.::GO:0004313; F:[acyl-carrier-protein S-acetyltransferase activity; IEA:EC.::GO:0004314; F:[acyl-carrier-protein S-malonyltransferase activity; IEA:EC.::GO:0000036; F:acyl carrier activity; IEA:InterPro.::GO:0048037; F:cofactor binding; IEA:InterPro.::GO:0004319; F:enoyl-[acyl-carrier-protein reductase (NADPH, B-specific) activity; IEA:EC.::GO:0016295; F:myristoyl-[acyl-carrier-protein hydrolase activity; IEA:EC.]::GO:0000166; F:nucleotide binding; IEA:InterPro.]::GO:0004320; F:oleoyl-[acyl-carrier-protein] hydrolase activity; IEA:EC.]::GO:0016296; F:palmitoyl-[acyl-carrier-protein] hydrolase activity; IEA:EC.]::GO:0031177; F:phosphopantetheine binding; IEA:InterPro.]::GO:0008270; F:zinc ion binding; IEA:InterPro.]
									GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.]
82	P40872	4262	PKSM_BACSU Polyketide synthase PksM OS=Bacill...	456	5e-18	90.9	24	39	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0000036; F:acyl carrier activity; IEA:InterPro.::GO:0048037; F:cofactor binding; IEA:InterPro.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0031177; F:phosphopantetheine binding; IEA:InterPro.::GO:0016747; F:transferase activity, transferring acyl groups other than amino-acyl groups; IEA:InterPro.
									GO:0017000; P:antibiotic biosynthetic process; IEA:UniProtKB-KW.
83	Q05470	4538	PKSL_BACSU Polyketide synthase PksL OS=Bacill...	283	0.000000000003	72.8	27	45	GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
									GO:0000036; F:acyl carrier activity; IEA:InterPro.::GO:0048037; F:cofactor binding; IEA:InterPro.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:InterPro.::GO:0031177; F:phosphopantetheine binding; IEA:InterPro.::GO:0016746; F:transferase activity, transferring acyl groups; IEA:UniProtKB-KW.
									GO:0017000; P:antibiotic biosynthetic process; IEA:UniProtKB-KW.
84	Q7TXL6	1488	PPSE_MYCBO Phthiocerol/phenolphthiocerol synt...	280	2e-18	91.7	30	47
									GO:0004315; F:3-oxoacyl-[acyl-carrier-protein synthase activity; IEA:EC.::GO:0000036; F:acyl carrier activity; IEA:InterPro.::GO:0048037; F:cofactor binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
									GO:0071766; P:Actinobacterium-type cell wall biogenesis; IMP:UniProtKB.::GO:0006631; P:fatty acid metabolic process; IEA:UniProtKB-KW.::GO:0008610; P:lipid biosynthetic process; IMP:UniProtKB.]
85	P96204	1488	PPSE_MYCTU Phthiocerol synthesis polyketide s...	280	2e-18	91.7	30	47	GO:0005618; C:cell wall; IDA:MTBBASE.::GO:0005886; C:plasma membrane; IDA:MTBBASE.
									GO:0004315; F:3-oxoacyl-[acyl-carrier-protein synthase activity; IDA:MTBBASE.::GO:0000036; F:acyl carrier activity; IEA:InterPro.::GO:0048037; F:cofactor binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:UniProtKB-KW.
									GO:0071770; P:DIM/DIP cell wall layer assembly; IDA:MTBBASE.::GO:0006633; P:fatty acid biosynthetic process; IDA:MTBBASE.]
86	P49327	2511	FAS_HUMAN Fatty acid synthase OS=Homo sapiens...	443	4e-18	91.3	24	41	GO:0005829; C:cytosol; TAS:Reactome.::GO:0005794; C:Golgi apparatus; IDA:HPA.::GO:0042470; C:melanosome; IEA:UniProtKB-SubCell.::GO:0005886; C:plasma membrane; IDA:HPA.
									GO:0004317; F:3-hydroxypalmitoyl-[acyl-carrier-protein dehydratase activity; IEA:EC.::GO:0004316; F:3-oxoacyl-[acyl-carrier-protein reductase (NADPH) activity; IEA:EC.::GO:0004315; F:3-oxoacyl-[acyl-carrier-protein synthase activity; IEA:EC.::GO:0004313; F:[acyl-carrier-protein S-acetyltransferase activity; IEA:EC.::GO:0004314; F:[acyl-carrier-protein S-malonyltransferase activity; IEA:EC.::GO:0000036; F:acyl carrier activity; IEA:InterPro.::GO:0048037; F:cofactor binding; IEA:InterPro.::GO:0004319; F:enoyl-[acyl-carrier-protein reductase (NADPH, B-specific) activity; IEA:EC.::GO:0016295; F:myristoyl-[acyl-carrier-protein hydrolase activity; IEA:EC.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0004320; F:oleoyl-[acyl-carrier-protein hydrolase activity; IEA:EC.::GO:0016296; F:palmitoyl-[acyl-carrier-protein hydrolase activity; IEA:EC.::GO:0031177; F:phosphopantetheine binding; IEA:InterPro.]::GO:0005515; F:protein binding; IPI:UniProtKB.]::GO:0008270; F:zinc ion binding; IEA:InterPro.]
									GO:0006112; P:energy reserve metabolic process; TAS:Reactome.]::GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.]::GO:0035338; P:long-chain fatty-acyl-CoA biosynthetic process; TAS:Reactome.]::GO:0015939; P:pantothenate metabolic process; TAS:Reactome.]::GO:0031325; P:positive regulation of cellular metabolic process; TAS:Reactome.]::GO:0019432; P:triglyceride biosynthetic process; TAS:Reactome.]
87	B0G103	2485	PKS10_DICDI Probable polyketide synthase 10 O...	286	5e-18	90.9	27	45
									GO:0000036; F:acyl carrier activity; IEA:InterPro.::GO:0048037; F:cofactor binding; IEA:InterPro.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
									GO:0009058; P:biosynthetic process; IEA:InterPro.
88	Q54IX3	2531	PKS26_DICDI Probable polyketide synthase 26 O...	360	5e-18	90.9	26	41
									GO:0000036; F:acyl carrier activity; IEA:InterPro.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:InterPro.::GO:0016747; F:transferase activity, transferring acyl groups other than amino-acyl groups; IEA:InterPro.
									GO:0009058; P:biosynthetic process; IEA:InterPro.
89	Q559A9	2551	PKS13_DICDI Probable polyketide synthase 13 O...	405	1e-17	89.7	26	41
									GO:0000036; F:acyl carrier activity; IEA:InterPro.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:InterPro.::GO:0016740; F:transferase activity; IEA:UniProtKB-KW.
									GO:0009058; P:biosynthetic process; IEA:InterPro.
90	Q54KU3	2380	PKS25_DICDI Probable polyketide synthase 25 O...	398	1e-17	89.7	26	44
									GO:0000036; F:acyl carrier activity; IEA:InterPro.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:InterPro.::GO:0016747; F:transferase activity, transferring acyl groups other than amino-acyl groups; IEA:InterPro.
									GO:0009058; P:biosynthetic process; IEA:InterPro.
91	Q54B49	3092	PKS45_DICDI Probable polyketide synthase 45 O...	290	2e-17	89.4	27	42	GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
									GO:0000036; F:acyl carrier activity; IEA:InterPro.::GO:0048037; F:cofactor binding; IEA:InterPro.::GO:0000166; F:nucleotide binding; IEA:InterPro.::GO:0016491; F:oxidoreductase activity; IEA:InterPro.::GO:0016747; F:transferase activity, transferring acyl groups other than amino-acyl groups; IEA:InterPro.
									GO:0009058; P:biosynthetic process; IEA:InterPro.

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